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Tag Content
UUCD2 ID IUUC-Fca-036359
UUCD1 version UUC-FeC-00780
Ensembl Protein ID ENSFCAP00000002195.3
UniProt Accession M3VYE7; M3VYE7_FELCA
Genbank Protein ID ENSFCAP00000002195
Protein Name Uncharacterized protein
Genbank Nucleotide ID AANG02009018
Gene Name USP37
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFCAG00000002380.3 ENSFCAT00000002380.3 ENSFCAP00000002195.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.10e-87 294.4 342 951
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +G++NlgNtCYmN++LQ+L+++++++++ll+   + ++++  k p ++l++ +++l+ +    +s++k+   +++++a++++ae+fsgy
   Q: 342  QGFSNLGNTCYMNAILQSLFSLQSFANDLLK---QGIPWK--KIPLNALIRRFAHLLVKKDicNSETKKDLLKKVKNAISATAERFSGY 425
           69*****************************...*****9..679999999999999776567************************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +q+Da+Efl+++ldql+e+++k  nk++++e    ++++sd+   + ++ +++++ ++++++++++i+c++c+++  ++e+f+dls+++
   Q: 426  MQNDAHEFLSQCLDQLKEDMEK-LNKTWKTEPVPGEETSSDI---SATRVYTCPVITNLEFEVQHSIICKACGEIIPKREQFNDLSIDL 510
           ********************55.8888888877777777777...7999**************************************** PP
   S: 177  pgkeetkke.slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
           p++++  ++ s+qd+L+ f+++eele    y+cekc +k+ a  ++k+++lP++LilhLkR+sf+ + + ++ki ++v +p+ L+ls++
   Q: 511  PRRKKPLPPrSIQDSLDLFFRAEELE----YSCEKCGGKC-ALVRHKFNRLPRILILHLKRYSFNVTLSLNNKIGQQVFIPRYLTLSSH 594
           *999886545***************9....*********9.89999******************************************* PP
   S: 265  cts...................................................................................... 267
           ct+                                                                                      
   Q: 595  CTEstkppftlgwsahtaisrplkasqmvnscitspstpsknftfkskcslalcldsdsedelkrsvalsqrlcevsgceqqqedlekd 683
           ***9****************************999999999999999999999999999999999999999999999999999998888 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 684  skscriepdkselensgfdgmseeellaavleiskreaspslshedddkptsspdtgfaeddiqempenqdpvetekpktlaepdpasf 772
           88888888888888888888888888888888888888888888888887777777777777777777777777777777777777777 PP
   S: 268  ...............peekqke................................................................... 274
                          p     e                                                                   
   Q: 773  teitkdcdenkenktP-----Egsqgevdwlqqydmerereeqelqqalaqslqeqeaweqkedddlkratelslqefnnsfldslgsd 856
           6666666655555550.....05555555555555555555555666666666666677777777777777777777888888888888 PP
   S: 275  ..............................kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaY 331
                                         +++Y+Li+vv+H G ++ssGHY+++v++ k++ W++++D +V++++e++v++++++++Y
   Q: 857  edsgnedvldmeyteaeaeelkrnaetgnlPHSYRLISVVSHIGsTSSSGHYISDVYDIKKQaWFTYNDLEVSKIQEASVQSDRDRSGY 945
           888888888888888888888899999999****************************99999************************** PP
   S: 332  vlfYkr 337
           ++fY++
   Q: 946  IFFYMH 951
           ****98 PP
   
Organism Felis catus
Protein Sequence
(Fasta)
MSPLKIHGPI RIRSMQTGIT KWKEGSFEIV EKENKVSLVV HYNTGGIPRI FQLSHNIKNV 60
VLRPSGAKQS RLMLTLQDNS FLSIDKVPSK DAEEMRLFLD AVHQNRLHTA MKPQGSGSFG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Fca-036359|DUB,USP|Felis catus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTGAGGTGAT GGCTTCCGGA GAACGGGCAT AGCTGCAGAA TATGAGTAGT TCCCCAAGAA 60
GAGTGCATTG CCTTTGGCAC AAGGATCAGA ATAAAGGTGA ATTGTTATTA CATAGGGTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Fca-036359|DUB,USP|Felis catus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR003903--UIM_dom
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
PF16674--UCH_N
PF02809--UIM
SMART

SM00726--UIM
Gene Ontology

GO:0005634--C:nucleus
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0006275--P:regulation of DNA replication
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG fca:101087769
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001400 Ailuropoda melanoleuca 97.35 0.00e+00 1786.00
IUUC-Apl-004033 Anas platyrhynchos 77.78 0.00e+00 1445.00
IUUC-Aca-005370 Anolis carolinensis 70.58 0.00e+00 1330.00
IUUC-Ame-011884 Astyanax mexicanus 57.84 0.00e+00 982.00
IUUC-Bta-012725 Bos taurus 95.20 0.00e+00 1721.00
IUUC-Cja-019939 Callithrix jacchus 94.90 0.00e+00 1683.00
IUUC-Cfa-020835 Canis familiaris 97.35 0.00e+00 1831.00
IUUC-Cpo-022067 Cavia porcellus 93.54 0.00e+00 1565.00
IUUC-Cre-022867 Chlamydomonas reinhardtii 29.22 6.00e-24 105.00
IUUC-Csa-023085 Chlorocebus sabaeus 95.00 0.00e+00 1746.00
IUUC-Cho-024390 Choloepus hoffmanni 87.11 3.00e-167 582.00
IUUC-Cin-025496 Ciona intestinalis 37.65 8.00e-44 171.00
IUUC-Csv-025812 Ciona savignyi 36.61 8.00e-42 165.00
IUUC-Dre-028255 Danio rerio 57.00 0.00e+00 944.00
IUUC-Dno-028986 Dasypus novemcinctus 94.40 0.00e+00 1702.00
IUUC-Dor-031062 Dipodomys ordii 79.65 0.00e+00 879.00
IUUC-Ete-032359 Echinops telfairi 83.33 0.00e+00 828.00
IUUC-Eca-033964 Equus caballus 95.82 0.00e+00 1761.00
IUUC-Eeu-034492 Erinaceus europaeus 86.03 0.00e+00 830.00
IUUC-Fal-037640 Ficedula albicollis 78.28 0.00e+00 1418.00
IUUC-Gmo-039600 Gadus morhua 54.44 0.00e+00 935.00
IUUC-Gga-040126 Gallus gallus 77.78 0.00e+00 1378.00
IUUC-Gac-041557 Gasterosteus aculeatus 54.05 0.00e+00 912.00
IUUC-Ggo-045571 Gorilla gorilla 89.56 0.00e+00 1508.00
IUUC-Hsa-046043 Homo sapiens 93.99 0.00e+00 1699.00
IUUC-Itr-048207 Ictidomys tridecemlineatus 93.26 0.00e+00 1693.00
IUUC-Lch-050357 Latimeria chalumnae 64.47 0.00e+00 1050.00
IUUC-Loc-052849 Lepisosteus oculatus 61.30 0.00e+00 1009.00
IUUC-Laf-054570 Loxodonta africana 93.48 0.00e+00 1672.00
IUUC-Mcc-054989 Macaca mulatta 94.85 0.00e+00 1611.00
IUUC-Meu-056273 Macropus eugenii 64.53 5.00e-171 595.00
IUUC-Mga-059814 Meleagris gallopavo 76.06 0.00e+00 1380.00
IUUC-Mmr-061726 Microcebus murinus 94.08 0.00e+00 1731.00
IUUC-Mdo-062974 Monodelphis domestica 84.92 0.00e+00 1572.00
IUUC-Mmu-064069 Mus musculus 90.00 0.00e+00 1610.00
IUUC-Mpu-066008 Mustela putorius furo 96.74 0.00e+00 1743.00
IUUC-Nle-069259 Nomascus leucogenys 95.00 0.00e+00 1702.00
IUUC-Opr-070882 Ochotona princeps 78.42 5.00e-140 492.00
IUUC-Ont-072441 Oreochromis niloticus 55.61 0.00e+00 935.00
IUUC-Oan-073151 Ornithorhynchus anatinus 77.70 3.00e-121 427.00
IUUC-Ocu-074879 Oryctolagus cuniculus 93.27 0.00e+00 1690.00
IUUC-Ola-087007 Oryzias latipes 53.50 0.00e+00 891.00
IUUC-Oga-088385 Otolemur garnettii 93.10 0.00e+00 1711.00
IUUC-Oar-090305 Ovis aries 95.20 0.00e+00 1752.00
IUUC-Ptr-091299 Pan troglodytes 94.69 0.00e+00 1704.00
IUUC-Pan-091996 Papio anubis 95.07 0.00e+00 1692.00
IUUC-Psi-093176 Pelodiscus sinensis 78.73 0.00e+00 1449.00
IUUC-Pma-094331 Petromyzon marinus 48.41 0.00e+00 762.00
IUUC-Pfo-096503 Poecilia formosa 55.79 0.00e+00 923.00
IUUC-Pab-098543 Pongo abelii 93.12 0.00e+00 904.00
IUUC-Pca-101099 Procavia capensis 87.95 0.00e+00 1316.00
IUUC-Pva-103163 Pteropus vampyrus 88.98 0.00e+00 1620.00
IUUC-Rno-105766 Rattus norvegicus 90.41 0.00e+00 1617.00
IUUC-Sha-106610 Sarcophilus harrisii 81.47 0.00e+00 1477.00
IUUC-Sar-113256 Sorex araneus 90.91 1.00e-113 404.00
IUUC-Ssc-116353 Sus scrofa 95.21 0.00e+00 1703.00
IUUC-Tgu-116971 Taeniopygia guttata 78.18 0.00e+00 1388.00
IUUC-Tru-117932 Takifugu rubripes 44.13 0.00e+00 642.00
IUUC-Tsy-119185 Tarsius syrichta 89.17 0.00e+00 1115.00
IUUC-Tni-119842 Tetraodon nigroviridis 59.81 2.00e-110 392.00
IUUC-Tbe-127281 Tupaia belangeri 82.98 0.00e+00 655.00
IUUC-Ttr-128177 Tursiops truncatus 96.14 0.00e+00 1358.00
IUUC-Vpa-130031 Vicugna pacos 95.81 0.00e+00 1792.00
IUUC-Xtr-132949 Xenopus tropicalis 65.66 0.00e+00 1166.00
Created Date 25-Jun-2017

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