iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000000884.4	ENSCAFT00000046940.2	ENSCAFP00000039782.1
ENSCAFG00000000884.4	ENSCAFT00000001375.3	ENSCAFP00000001261.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-25	88.4	554	588
UBD/Beta-Prp	1.30e-44	152.9	514	822

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH + v+ +++ +d + l+s+s Dgt+++W+lr+ 
   Q: 554  GHDGAVSTVCWsHDsRWLLSASQDGTLRLWSLRRA 588
           8***********77799**************9875 PP

UBD/Beta-Prp

   S: 11   svitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk..gheds 96
           +  +cv++ + d+++la g +++ + v++++   +   +sgh+++v++v++s+d+ +l+++s+D+t+++w+l+  +    +     ++ 
   Q: 514  AAAHCVQYsAGDGQWLACGLANHLLLVFRADLSGTPTVFSGHDGAVSTVCWSHDSRWLLSASQDGTLRLWSLRRAELALCVGkdVFSKP 602
           56789***999*********************9999999**********************************8777776662245788 PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlkt 168
           v+s +f+   d++v  s+   +++ + + ++c  e                + +g++++++  +v+++   l+ +++ +rt+ ++dl+ 
   Q: 603  VRSAQFYY-VDTFVLLSSGPELQLLKYHIDTCKDEiqrykqksrckrvfrlPTTGRTEITSLSAVNDFYsYLVLTAGRNRTLEVFDLNA 690
           99999998.89999999999999955555555555559999***************************978888*************99 PP
   S: 169  gkllrtltgghtdsvysls......fdsng....kelvsgsldgtvklwdlqtgecvrtlnght..dnvksvrfspnderlvsgssDgs 245
           g+      + h ++v+ +       f+ ++    + +++ +    +klwdl+t +c r+++gh     ++ ++fsp + +++sg++D+ 
   Q: 691  GRSAAMTVEVHSRPVHQICqnkgssFTTQQheayNLFATTASGDGIKLWDLRTLRCERRFEGHPnhGYPCGIAFSPCGRYVASGAEDRH 779
           9999888777********966777666655999999***************************84467899****************** PP
   S: 246  iriWdlrsgdllktlqlhnssvisvav..lsfgdnvlvlgsed 286
            +++dl s+++ + l++h+++v+sva+    +++n + + se+
   Q: 780  AYMYDLGSSTFSHRLAGHKDTVTSVAFspAAPQQNRMRSYSEE 822
           ***************************6666668877777664 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MGEPRGIFCS AQGCVGDVII EQRLVESKEP ASHVPLACSA QYCAFPVDGN VLCLWNTKDP 60
SYQPLTLQGH HEPITAVAFG NTVSPLLICS ASQDYVIMWS LDECRQKVLQ GLSPRGVIMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGAGAAC CACGAGGGAT TTTCTGCTCT GCCCAGGGCT GTGTTGGTGA CGTGATCATA 60
GAACAGCGCC TGGTAGAGTC AAAGGAGCCT GCGTCCCACG TGCCGCTCGC TTGCAGCGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002258	Ailuropoda melanoleuca	80.31	0.00e+00	1140.00
IUUC-Aca-004807	Anolis carolinensis	56.83	0.00e+00	944.00
IUUC-Bta-013316	Bos taurus	65.69	0.00e+00	1038.00
IUUC-Cja-018825	Callithrix jacchus	64.89	0.00e+00	1091.00
IUUC-Cpo-022282	Cavia porcellus	60.22	0.00e+00	993.00
IUUC-Csa-023439	Chlorocebus sabaeus	66.71	0.00e+00	1028.00
IUUC-Cho-025046	Choloepus hoffmanni	56.02	0.00e+00	637.00
IUUC-Dre-028376	Danio rerio	41.82	4.00e-166	578.00
IUUC-Dno-029649	Dasypus novemcinctus	66.85	0.00e+00	912.00
IUUC-Dor-030824	Dipodomys ordii	55.98	0.00e+00	704.00
IUUC-Eca-033270	Equus caballus	70.73	0.00e+00	1188.00
IUUC-Fca-036149	Felis catus	75.12	0.00e+00	1255.00
IUUC-Fal-037410	Ficedula albicollis	53.63	0.00e+00	706.00
IUUC-Gmo-038923	Gadus morhua	37.67	7.00e-123	434.00
IUUC-Gga-040974	Gallus gallus	52.01	0.00e+00	817.00
IUUC-Gac-042310	Gasterosteus aculeatus	36.36	2.00e-106	380.00
IUUC-Ggo-044557	Gorilla gorilla	65.91	0.00e+00	1110.00
IUUC-Hsa-046312	Homo sapiens	66.31	0.00e+00	1118.00
IUUC-Itr-049033	Ictidomys tridecemlineatus	63.07	0.00e+00	1006.00
IUUC-Laf-054450	Loxodonta africana	63.29	0.00e+00	977.00
IUUC-Mcc-055807	Macaca mulatta	61.16	0.00e+00	868.00
IUUC-Meu-056116	Macropus eugenii	40.10	9.00e-69	254.00
IUUC-Mga-060088	Meleagris gallopavo	51.90	0.00e+00	718.00
IUUC-Mdo-062857	Monodelphis domestica	59.70	0.00e+00	976.00
IUUC-Mmu-063220	Mus musculus	61.87	0.00e+00	875.00
IUUC-Mpu-066921	Mustela putorius furo	74.85	0.00e+00	1188.00
IUUC-Mlu-067717	Myotis lucifugus	61.38	0.00e+00	796.00
IUUC-Nle-069061	Nomascus leucogenys	53.96	0.00e+00	857.00
IUUC-Opr-070612	Ochotona princeps	59.69	3.00e-83	303.00
IUUC-Ont-072187	Oreochromis niloticus	42.33	1.00e-165	577.00
IUUC-Oan-072701	Ornithorhynchus anatinus	54.25	2.00e-135	475.00
IUUC-Ocu-074602	Oryctolagus cuniculus	63.57	0.00e+00	1048.00
IUUC-Ola-086633	Oryzias latipes	36.98	2.00e-129	456.00
IUUC-Oga-088499	Otolemur garnettii	64.71	0.00e+00	1060.00
IUUC-Oar-089256	Ovis aries	65.12	0.00e+00	1019.00
IUUC-Ptr-091545	Pan troglodytes	61.03	0.00e+00	681.00
IUUC-Pan-092299	Papio anubis	65.76	0.00e+00	1086.00
IUUC-Psi-093010	Pelodiscus sinensis	55.96	0.00e+00	909.00
IUUC-Pab-097646	Pongo abelii	59.08	0.00e+00	657.00
IUUC-Pca-100720	Procavia capensis	53.61	7.00e-138	484.00
IUUC-Pva-102808	Pteropus vampyrus	58.72	0.00e+00	889.00
IUUC-Rno-105715	Rattus norvegicus	61.94	0.00e+00	984.00
IUUC-Sha-107546	Sarcophilus harrisii	56.33	0.00e+00	951.00
IUUC-Sar-113543	Sorex araneus	53.35	0.00e+00	811.00
IUUC-Ssc-116335	Sus scrofa	78.33	3.00e-53	201.00
IUUC-Tgu-117249	Taeniopygia guttata	52.70	0.00e+00	751.00
IUUC-Tsy-119238	Tarsius syrichta	62.99	0.00e+00	828.00
IUUC-Tni-120639	Tetraodon nigroviridis	36.24	2.00e-54	206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence