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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046312
Ensembl Protein ID ENSP00000416289.1
UniProt Accession A2RRH5; A5PLM8; C9JGV0; Q5T066; WDR27_HUMAN
Genbank Protein ID CAI12313.1; AAI31634.1; AAI42983.1
Protein Name WD repeat-containing protein 27
Genbank Nucleotide ID AL031315; BC040606; BC142982
Gene Name WDR27
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000184465.15 ENST00000448612.5 ENSP00000416289.1
ENSG00000184465.15 ENST00000423258.5 ENSP00000397869.1
ENSG00000184465.15 ENST00000441385.2 ENSP00000411915.2
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
THPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmicroRNATRANSFACTargetScan
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDHINTInWeb_IM
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTM
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.10e-22 80.8 583 613
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH + v+++++ +d + l+s+++Dgt+++W+
   Q: 583  GHDGAVNAVCWsQDrRWLLSAARDGTLRMWS 613
           8***********99999*************8 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MENPQDIFSS NGGCLSDIVI EKYLVESKES VSHVQLACSM QDCAFPLDGT ELCIWNTKDP 60
SHQLLILRGH HQPITAMAFG NKVNPLLICS ASLDYVIMWN LDECREKVLQ GLVPRGTVMG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046312|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGAGGGGCGG CGGGCTAGTA ACCATAGCGG CTCGCGTGGG TCGGCTGGCA AGTAACCATA 60
GCGGCGAGCG TGGGGCGGAG TGTGGCTCGG TAGTCCTCTG CGTGCCCTCC TGGGAGCTGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046312|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005654--C:nucleoplasm
KEGG hsa:253769
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002258 Ailuropoda melanoleuca 63.05 0.00e+00 885.00
IUUC-Aca-004807 Anolis carolinensis 55.62 0.00e+00 926.00
IUUC-Bta-013316 Bos taurus 62.88 0.00e+00 1022.00
IUUC-Cja-018825 Callithrix jacchus 87.38 0.00e+00 1512.00
IUUC-Cfa-020895 Canis familiaris 66.31 0.00e+00 1122.00
IUUC-Cpo-022282 Cavia porcellus 61.46 0.00e+00 1049.00
IUUC-Csa-023439 Chlorocebus sabaeus 88.79 0.00e+00 1438.00
IUUC-Cho-025046 Choloepus hoffmanni 60.39 0.00e+00 700.00
IUUC-Dre-028376 Danio rerio 40.90 1.00e-163 570.00
IUUC-Dno-029649 Dasypus novemcinctus 69.80 0.00e+00 989.00
IUUC-Dor-030824 Dipodomys ordii 59.09 0.00e+00 758.00
IUUC-Eca-033270 Equus caballus 68.41 0.00e+00 1171.00
IUUC-Fca-036149 Felis catus 63.15 0.00e+00 1059.00
IUUC-Fal-037410 Ficedula albicollis 53.67 0.00e+00 719.00
IUUC-Gmo-038923 Gadus morhua 38.78 6.00e-126 444.00
IUUC-Gga-040974 Gallus gallus 49.59 0.00e+00 806.00
IUUC-Gac-042310 Gasterosteus aculeatus 37.52 8.00e-110 391.00
IUUC-Ggo-044557 Gorilla gorilla 96.93 0.00e+00 1665.00
IUUC-Itr-049033 Ictidomys tridecemlineatus 62.23 0.00e+00 1031.00
IUUC-Laf-054450 Loxodonta africana 64.89 0.00e+00 1009.00
IUUC-Mcc-055807 Macaca mulatta 85.77 0.00e+00 1285.00
IUUC-Meu-056116 Macropus eugenii 40.10 5.00e-76 279.00
IUUC-Mga-060088 Meleagris gallopavo 49.41 0.00e+00 697.00
IUUC-Mdo-062857 Monodelphis domestica 58.56 0.00e+00 1001.00
IUUC-Mmu-063220 Mus musculus 60.85 0.00e+00 900.00
IUUC-Mpu-066921 Mustela putorius furo 61.89 0.00e+00 992.00
IUUC-Mlu-067717 Myotis lucifugus 57.27 0.00e+00 746.00
IUUC-Nle-069061 Nomascus leucogenys 80.92 0.00e+00 1331.00
IUUC-Opr-070612 Ochotona princeps 61.24 3.00e-84 306.00
IUUC-Ont-072187 Oreochromis niloticus 42.49 9.00e-179 620.00
IUUC-Oan-072701 Ornithorhynchus anatinus 51.24 4.00e-130 458.00
IUUC-Ocu-074602 Oryctolagus cuniculus 64.57 0.00e+00 1074.00
IUUC-Ola-086633 Oryzias latipes 36.31 4.00e-126 445.00
IUUC-Oga-088499 Otolemur garnettii 67.48 0.00e+00 1131.00
IUUC-Oar-089256 Ovis aries 61.87 0.00e+00 1004.00
IUUC-Ptr-091545 Pan troglodytes 98.97 0.00e+00 1153.00
IUUC-Pan-092299 Papio anubis 86.74 0.00e+00 1508.00
IUUC-Psi-093010 Pelodiscus sinensis 55.78 0.00e+00 923.00
IUUC-Pab-097646 Pongo abelii 85.47 0.00e+00 1076.00
IUUC-Pca-100720 Procavia capensis 55.31 5.00e-149 521.00
IUUC-Pva-102808 Pteropus vampyrus 59.10 0.00e+00 890.00
IUUC-Rno-105715 Rattus norvegicus 63.27 0.00e+00 1013.00
IUUC-Sha-107546 Sarcophilus harrisii 55.45 0.00e+00 970.00
IUUC-Sar-113543 Sorex araneus 53.60 0.00e+00 816.00
IUUC-Ssc-116335 Sus scrofa 71.64 3.00e-51 195.00
IUUC-Tgu-117249 Taeniopygia guttata 49.53 0.00e+00 721.00
IUUC-Tsy-119238 Tarsius syrichta 65.91 0.00e+00 1101.00
IUUC-Tni-120639 Tetraodon nigroviridis 33.41 1.00e-52 200.00
Created Date 25-Jun-2017

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