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Tag Content
UUCD2 ID IUUC-Nle-069914
UUCD1 version UUC-NoL-00733
Ensembl Protein ID ENSNLEP00000017833.1
UniProt Accession G1RX56; G1RX56_NOMLE
Genbank Protein ID ENSNLEP00000017833
Protein Name tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4
Genbank Nucleotide ID ADFV01126112
Gene Name WDR4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSNLEG00000014641.1 ENSNLET00000018723.1 ENSNLEP00000017833.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.00e-07 31.1 186 225
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+ ++   +  +ll+s+s+Dgt+++W++r+g++l+
   Q: 186  GHTEFVSRISVvpTQpGLLLSSSGDGTLRLWEYRSGRQLH 225
           67777777776853369*******************9986 PP
   
Organism Nomascus leucogenys
Functional Description
(View)

Functional Description


     Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
 Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Protein Sequence
(Fasta)
MAGSVGLALC GQTLVVRGGS RFLATSTASS DDDSLFIYDC SAAEKKSQEN KGEDAPLDQG 60
SVAILASTFS KSGSYFALTD DSKRLILFRT KPWQCLSVRX XXXXXXXLTF IASEEKVLVA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Nle-069914|E3,WD_repeat|Nomascus leucogenys
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGTCACCGA CCGGTGCGGA CAGGAAGAGG CTCTGGGCTG GCACATGTGT ATGGCGGCGA 60
GGCGGGCGGG TACATGGCGG GCTCTGTGGG ACTGGCGTTG TGCGGTCAGA CACTGGTGGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Nle-069914|E3,WD_repeat|Nomascus leucogenys
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat
Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000556 Aegilops tauschii 32.52 2.00e-09 57.00
IUUC-Apl-003975 Anas platyrhynchos 58.11 7.00e-115 407.00
IUUC-Aca-005170 Anolis carolinensis 52.88 1.00e-98 353.00
IUUC-Aly-005769 Arabidopsis lyrata 29.22 2.00e-21 96.30
IUUC-Ath-006733 Arabidopsis thaliana 33.85 1.00e-20 94.00
IUUC-Acl-008151 Aspergillus clavatus 35.37 4.00e-16 79.30
IUUC-Afl-008518 Aspergillus flavus 34.25 7.00e-17 81.30
IUUC-Afu-009102 Aspergillus fumigatus 40.13 3.00e-14 73.20
IUUC-Ani-009442 Aspergillus nidulans 28.17 2.00e-13 70.90
IUUC-Aor-010133 Aspergillus oryzae 27.20 3.00e-18 86.70
IUUC-Ate-010465 Aspergillus terreus 37.29 3.00e-14 73.20
IUUC-Ame-010613 Astyanax mexicanus 44.83 4.00e-83 301.00
IUUC-Bgr-012067 Blumeria graminis 45.88 4.00e-18 85.90
IUUC-Bta-012788 Bos taurus 78.45 3.00e-176 610.00
IUUC-Bdi-014458 Brachypodium distachyon 30.65 3.00e-16 79.70
IUUC-Bol-015373 Brassica oleracea 34.78 6.00e-20 93.20
IUUC-Bra-016644 Brassica rapa 35.91 5.00e-20 93.60
IUUC-Cpo-021963 Cavia porcellus 78.04 2.00e-165 574.00
IUUC-Csa-024148 Chlorocebus sabaeus 94.66 0.00e+00 669.00
IUUC-Cne-026834 Cryptococcus neoformans 35.04 5.00e-16 79.00
IUUC-Dre-028427 Danio rerio 47.09 3.00e-86 311.00
IUUC-Dno-028881 Dasypus novemcinctus 69.38 2.00e-153 535.00
IUUC-Dor-030522 Dipodomys ordii 73.57 4.00e-159 553.00
IUUC-Dme-032136 Drosophila melanogaster 32.04 1.00e-23 104.00
IUUC-Fca-035833 Felis catus 73.72 1.00e-162 565.00
IUUC-Fal-037497 Ficedula albicollis 55.73 3.00e-113 401.00
IUUC-Gga-040547 Gallus gallus 56.91 5.00e-118 417.00
IUUC-Gac-041761 Gasterosteus aculeatus 42.29 2.00e-77 282.00
IUUC-Gma-043941 Glycine max 34.78 2.00e-22 99.80
IUUC-Ggo-045340 Gorilla gorilla 94.90 0.00e+00 725.00
IUUC-Hsa-046403 Homo sapiens 95.15 0.00e+00 727.00
IUUC-Hvu-047643 Hordeum vulgare 37.64 1.00e-16 80.90
IUUC-Itr-048103 Ictidomys tridecemlineatus 79.18 8.00e-174 602.00
IUUC-Kpa-049283 Komagataella pastoris 35.71 1.00e-16 80.50
IUUC-Lch-050682 Latimeria chalumnae 47.90 5.00e-101 360.00
IUUC-Lpe-050712 Leersia perrieri 29.92 4.00e-20 92.40
IUUC-Loc-052599 Lepisosteus oculatus 50.61 3.00e-110 391.00
IUUC-Laf-054390 Loxodonta africana 76.27 7.00e-171 593.00
IUUC-Mcc-054747 Macaca mulatta 94.17 0.00e+00 695.00
IUUC-Mtr-058600 Medicago truncatula 37.02 2.00e-21 96.30
IUUC-Mla-059129 Melampsora laricipopulina 25.52 4.00e-10 58.50
IUUC-Mga-059876 Meleagris gallopavo 55.64 1.00e-116 412.00
IUUC-Mvi-060359 Microbotryum violaceum 29.41 1.00e-11 64.70
IUUC-Mmr-061518 Microcebus murinus 81.36 0.00e+00 634.00
IUUC-Mac-065625 Musa acuminata 32.45 7.00e-17 81.60
IUUC-Nfi-068402 Neosartorya fischeri 38.56 8.00e-15 75.10
IUUC-Ont-071555 Oreochromis niloticus 40.21 5.00e-72 265.00
IUUC-Oan-072951 Ornithorhynchus anatinus 66.07 2.00e-145 508.00
IUUC-Ocu-074679 Oryctolagus cuniculus 80.38 2.00e-165 575.00
IUUC-Obr-076769 Oryza brachyantha 30.77 3.00e-20 92.80
IUUC-Ogl-077168 Oryza glaberrima 30.24 2.00e-21 97.10
IUUC-Oin-079207 Oryza indica 30.24 2.00e-21 97.10
IUUC-Opu-084031 Oryza punctata 30.41 1.00e-19 90.90
IUUC-Osa-085327 Oryza sativa 30.24 2.00e-21 97.10
IUUC-Ola-086716 Oryzias latipes 42.37 2.00e-72 266.00
IUUC-Olu-087708 Ostreococcus lucimarinus 26.60 2.00e-11 63.50
IUUC-Oar-090239 Ovis aries 79.52 6.00e-167 580.00
IUUC-Ptr-090851 Pan troglodytes 95.39 0.00e+00 728.00
IUUC-Pan-092558 Papio anubis 94.93 0.00e+00 669.00
IUUC-Psi-093792 Pelodiscus sinensis 58.15 3.00e-124 437.00
IUUC-Ppa-095757 Physcomitrella patens 38.82 1.00e-18 87.40
IUUC-Pfo-096465 Poecilia formosa 40.57 2.00e-79 288.00
IUUC-Pab-097722 Pongo abelii 94.90 0.00e+00 721.00
IUUC-Pop-098979 Populus trichocarpa 34.59 2.00e-18 86.70
IUUC-Pca-100753 Procavia capensis 74.74 2.00e-115 408.00
IUUC-Ppe-101515 Prunus persica 32.84 3.00e-17 82.80
IUUC-Sja-107780 Schizosaccharomyces japonicus 39.56 2.00e-11 63.20
IUUC-Spo-108251 Schizosaccharomyces pombe 37.89 3.00e-10 59.70
IUUC-Smo-108938 Selaginella moellendorffii 36.27 4.00e-21 95.90
IUUC-Sit-110020 Setaria italica 34.02 4.00e-19 89.00
IUUC-Sly-111543 Solanum lycopersicum 32.07 5.00e-19 89.00
IUUC-Stu-111925 Solanum tuberosum 32.61 2.00e-19 90.50
IUUC-Sbi-114061 Sorghum bicolor 30.74 3.00e-19 89.40
IUUC-Tgu-117321 Taeniopygia guttata 56.98 1.00e-106 379.00
IUUC-Tru-118454 Takifugu rubripes 42.78 6.00e-75 274.00
IUUC-Tni-119894 Tetraodon nigroviridis 42.08 4.00e-72 265.00
IUUC-Tca-121746 Theobroma cacao 34.03 7.00e-19 88.20
IUUC-Tae-124114 Triticum aestivum 37.08 4.00e-16 79.00
IUUC-Tur-126254 Triticum urartu 27.16 1.00e-11 63.50
IUUC-Tbe-127683 Tupaia belangeri 55.42 5.00e-58 218.00
IUUC-Ttr-129056 Tursiops truncatus 74.09 6.00e-156 543.00
IUUC-Vvi-131428 Vitis vinifera 34.72 1.00e-18 87.40
IUUC-Xma-133605 Xiphophorus maculatus 40.62 1.00e-79 290.00
Created Date 25-Jun-2017

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