iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090527

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03102159

Gene Name

RFWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000008348.4	ENSPTRT00000015393.4	ENSPTRP00000014254.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.60e-09	35.6	495	533

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtgvllk 37
           H   +++laf s   +ll+s+s D+tik+ +l t+++++
   Q: 495  HGKQIRGLAFsSYlrGLLLSASLDNTIKLTSLETNTVVQ 533
           8889******8445599***********98888877766 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAHEAMEYDL QVQLNHAEQQ PAPAGMASSQ GGPALLQPVP ADVVSSQGVP SILQPAPAEV 60
ISSQATPPLL QPAPQLSVDL TEVEVLGEDN VENINPRTSE QHRQGSDANH TIPASSLHST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGTGGCAGT TGGCGTAGGT GCATTCGGAG TTAGGCCGAG GTAACTACCG AGTCTTCGGC 60
GGGCTCGCGA GCCCGGCCGC GGCCTACTGG TTTCAGGTGA GGAGGGGTGT TGCTTCTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0035861--C:site of double-strand break
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:2000001--P:regulation of DNA damage checkpoint
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000929	Aegilops tauschii	22.88	5.00e-13	69.30
IUUC-Aml-001188	Ailuropoda melanoleuca	78.72	0.00e+00	1134.00
IUUC-Atr-003034	Amborella trichopoda	26.86	6.00e-17	81.30
IUUC-Apl-003182	Anas platyrhynchos	61.58	0.00e+00	713.00
IUUC-Aca-004619	Anolis carolinensis	69.03	0.00e+00	730.00
IUUC-Aly-006391	Arabidopsis lyrata	28.98	5.00e-29	122.00
IUUC-Ath-007300	Arabidopsis thaliana	28.62	4.00e-28	119.00
IUUC-Ame-010890	Astyanax mexicanus	59.72	0.00e+00	627.00
IUUC-Bta-013051	Bos taurus	72.90	0.00e+00	1040.00
IUUC-Bdi-014519	Brachypodium distachyon	26.52	5.00e-18	85.90
IUUC-Bol-015271	Brassica oleracea	29.54	3.00e-28	120.00
IUUC-Bra-017931	Brassica rapa	29.23	7.00e-28	118.00
IUUC-Cja-019240	Callithrix jacchus	88.00	0.00e+00	1263.00
IUUC-Cfa-021010	Canis familiaris	76.83	0.00e+00	1123.00
IUUC-Cpo-022308	Cavia porcellus	72.82	0.00e+00	968.00
IUUC-Csa-023501	Chlorocebus sabaeus	96.38	0.00e+00	1472.00
IUUC-Cho-024900	Choloepus hoffmanni	69.50	0.00e+00	989.00
IUUC-Cin-025403	Ciona intestinalis	36.80	2.00e-93	337.00
IUUC-Csv-025819	Ciona savignyi	37.11	1.00e-44	172.00
IUUC-Cme-027123	Cyanidioschyzon merolae	25.20	7.00e-18	85.50
IUUC-Dre-028354	Danio rerio	57.23	6.00e-165	574.00
IUUC-Dno-029400	Dasypus novemcinctus	73.03	0.00e+00	1050.00
IUUC-Dor-030320	Dipodomys ordii	73.38	0.00e+00	835.00
IUUC-Dme-031949	Drosophila melanogaster	27.00	7.00e-43	168.00
IUUC-Ete-032691	Echinops telfairi	56.96	1.00e-139	490.00
IUUC-Eca-034320	Equus caballus	80.57	0.00e+00	1220.00
IUUC-Fca-035732	Felis catus	77.79	0.00e+00	1082.00
IUUC-Fal-036648	Ficedula albicollis	69.90	0.00e+00	723.00
IUUC-Gmo-038609	Gadus morhua	56.90	6.00e-141	493.00
IUUC-Gga-040522	Gallus gallus	70.00	3.00e-105	375.00
IUUC-Gac-042318	Gasterosteus aculeatus	55.53	4.00e-134	471.00
IUUC-Gma-043184	Glycine max	26.33	1.00e-23	105.00
IUUC-Ggo-044464	Gorilla gorilla	98.84	0.00e+00	1490.00
IUUC-Hsa-045991	Homo sapiens	99.10	0.00e+00	1485.00
IUUC-Hvu-047705	Hordeum vulgare	23.93	1.00e-25	110.00
IUUC-Itr-047977	Ictidomys tridecemlineatus	79.77	0.00e+00	1162.00
IUUC-Lch-050112	Latimeria chalumnae	64.47	0.00e+00	663.00
IUUC-Lpe-051605	Leersia perrieri	27.10	1.00e-15	77.80
IUUC-Loc-052241	Lepisosteus oculatus	63.89	0.00e+00	643.00
IUUC-Laf-054559	Loxodonta africana	74.85	0.00e+00	948.00
IUUC-Mcc-055093	Macaca mulatta	95.74	0.00e+00	1441.00
IUUC-Meu-056417	Macropus eugenii	65.23	0.00e+00	676.00
IUUC-Mtr-058533	Medicago truncatula	25.00	5.00e-29	122.00
IUUC-Mga-059498	Meleagris gallopavo	60.94	0.00e+00	708.00
IUUC-Mmr-061782	Microcebus murinus	76.05	0.00e+00	1127.00
IUUC-Mdo-062053	Monodelphis domestica	71.92	0.00e+00	753.00
IUUC-Mmu-063352	Mus musculus	66.32	0.00e+00	978.00
IUUC-Mac-064582	Musa acuminata	25.75	1.00e-18	88.20
IUUC-Mpu-066087	Mustela putorius furo	76.61	0.00e+00	1130.00
IUUC-Mlu-068147	Myotis lucifugus	75.27	0.00e+00	1032.00
IUUC-Nle-069503	Nomascus leucogenys	94.06	0.00e+00	1402.00
IUUC-Opr-070479	Ochotona princeps	68.04	0.00e+00	983.00
IUUC-Ont-071700	Oreochromis niloticus	58.45	3.00e-171	595.00
IUUC-Oan-073702	Ornithorhynchus anatinus	74.19	0.00e+00	773.00
IUUC-Ocu-074886	Oryctolagus cuniculus	74.78	0.00e+00	1109.00
IUUC-Oba-075729	Oryza barthii	28.16	2.00e-22	100.00
IUUC-Obr-076562	Oryza brachyantha	26.20	2.00e-18	87.00
IUUC-Ogl-077615	Oryza glaberrima	28.16	2.00e-22	100.00
IUUC-Ogu-078921	Oryza glumaepatula	27.83	5.00e-22	99.40
IUUC-Oin-079250	Oryza indica	26.98	8.00e-16	78.60
IUUC-Olo-080758	Oryza longistaminata	26.06	2.00e-20	93.60
IUUC-Ome-081707	Oryza meridionalis	27.62	1.00e-17	84.70
IUUC-Oni-083006	Oryza nivara	25.09	9.00e-22	98.20
IUUC-Opu-083650	Oryza punctata	26.84	9.00e-22	98.60
IUUC-Oru-084924	Oryza rufipogon	27.63	3.00e-22	99.80
IUUC-Osa-085820	Oryza sativa	27.83	9.00e-22	98.20
IUUC-Ola-087229	Oryzias latipes	57.86	5.00e-139	487.00
IUUC-Oga-088243	Otolemur garnettii	73.37	0.00e+00	1037.00
IUUC-Oar-089461	Ovis aries	75.42	0.00e+00	1127.00
IUUC-Pan-092431	Papio anubis	95.87	0.00e+00	1372.00
IUUC-Psi-093156	Pelodiscus sinensis	55.08	0.00e+00	762.00
IUUC-Pno-094897	Phaeosphaeria nodorum	24.58	9.00e-07	47.80
IUUC-Ppa-095305	Physcomitrella patens	42.74	3.00e-18	87.40
IUUC-Pfo-097065	Poecilia formosa	57.09	6.00e-164	570.00
IUUC-Pab-098272	Pongo abelii	98.19	0.00e+00	1504.00
IUUC-Pop-099827	Populus trichocarpa	30.29	4.00e-31	129.00
IUUC-Pca-100713	Procavia capensis	63.45	0.00e+00	905.00
IUUC-Ppe-102103	Prunus persica	24.34	7.00e-30	125.00
IUUC-Pva-103133	Pteropus vampyrus	83.86	0.00e+00	732.00
IUUC-Sha-107628	Sarcophilus harrisii	56.98	0.00e+00	802.00
IUUC-Sit-109781	Setaria italica	29.07	5.00e-23	102.00
IUUC-Sly-111779	Solanum lycopersicum	31.73	3.00e-31	129.00
IUUC-Stu-112817	Solanum tuberosum	41.74	7.00e-17	80.90
IUUC-Sar-113124	Sorex araneus	63.09	0.00e+00	682.00
IUUC-Sbi-114107	Sorghum bicolor	24.95	5.00e-25	109.00
IUUC-Ssc-115850	Sus scrofa	76.69	0.00e+00	1109.00
IUUC-Tgu-117295	Taeniopygia guttata	69.55	0.00e+00	735.00
IUUC-Tru-117539	Takifugu rubripes	55.68	5.00e-167	580.00
IUUC-Tsy-118805	Tarsius syrichta	71.96	1.00e-113	404.00
IUUC-Tni-120274	Tetraodon nigroviridis	58.30	2.00e-167	581.00
IUUC-Tca-121162	Theobroma cacao	30.96	4.00e-28	119.00
IUUC-Tae-124822	Triticum aestivum	24.39	2.00e-26	114.00
IUUC-Tur-126162	Triticum urartu	25.00	6.00e-15	76.30
IUUC-Tbe-127884	Tupaia belangeri	72.69	3.00e-82	299.00
IUUC-Ttr-128665	Tursiops truncatus	71.98	0.00e+00	982.00
IUUC-Vpa-130385	Vicugna pacos	79.92	0.00e+00	1130.00
IUUC-Vvi-131464	Vitis vinifera	29.10	5.00e-23	102.00
IUUC-Xtr-132015	Xenopus tropicalis	61.12	0.00e+00	706.00
IUUC-Xma-133109	Xiphophorus maculatus	57.52	7.00e-164	570.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence