iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013483

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02049086

Gene Name

SOCS7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000008535.1	ENSBTAT00000011251.1	ENSBTAP00000011251.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.70e-14	53.6	502	549

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           +++ +++s++ SLqhLCR++Ir++++++++   + LPLPk L++Y++++ y
   Q: 502  LYPVSRFSNVKSLQHLCRFRIRQLVRIDHI---PDLPLPKPLISYIRKFYY 549
           567899*********************998...*************99976 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MVFRNVGRPP EEEDAEAAQE PGPSELLCPR HRCALDPKAL PPGLALERTW GPAAGLEAQL 60
AALGLGQPAG PGVKTVGGGC CPCPCPPQPP PPQPQPPAAA PQAGEDPTET SDALLVLEGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGTTCC GCAACGTGGG TCGGCCGCCG GAGGAGGAGG ACGCGGAGGC GGCCCAGGAG 60
CCGGGACCCT CGGAACTGCT CTGTCCCCGG CACCGCTGTG CCCTGGACCC CAAGGCCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028423--SOCS7
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0045444--P:fat cell differentiation
GO:0008286--P:insulin receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0021819--P:layer formation in cerebral cortex
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination
GO:0021942--P:radial glia guided migration of Purkinje cell

KEGG

bta:540586

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001668	Ailuropoda melanoleuca	92.19	0.00e+00	655.00
IUUC-Apl-003277	Anas platyrhynchos	91.78	5.00e-73	265.00
IUUC-Aca-004639	Anolis carolinensis	98.88	1.00e-107	381.00
IUUC-Ame-011301	Astyanax mexicanus	70.67	2.00e-130	458.00
IUUC-Cel-018643	Caenorhabditis elegans	30.30	2.00e-11	62.00
IUUC-Cja-019765	Callithrix jacchus	99.69	1.00e-162	565.00
IUUC-Cfa-020109	Canis familiaris	94.04	0.00e+00	659.00
IUUC-Cpo-021555	Cavia porcellus	95.50	1.00e-176	612.00
IUUC-Csa-023580	Chlorocebus sabaeus	96.22	0.00e+00	707.00
IUUC-Cho-024431	Choloepus hoffmanni	100.00	9.00e-71	260.00
IUUC-Dre-028183	Danio rerio	70.92	4.00e-139	488.00
IUUC-Dno-028858	Dasypus novemcinctus	96.19	0.00e+00	749.00
IUUC-Dor-031071	Dipodomys ordii	79.31	3.00e-113	400.00
IUUC-Dme-031876	Drosophila melanogaster	43.65	2.00e-43	171.00
IUUC-Ete-032928	Echinops telfairi	71.17	3.00e-101	362.00
IUUC-Eca-033250	Equus caballus	93.94	2.00e-176	611.00
IUUC-Eeu-034946	Erinaceus europaeus	88.42	7.00e-55	207.00
IUUC-Fca-036589	Felis catus	96.64	0.00e+00	653.00
IUUC-Fal-037316	Ficedula albicollis	92.61	9.00e-111	392.00
IUUC-Gmo-038552	Gadus morhua	91.26	1.00e-53	201.00
IUUC-Gga-041248	Gallus gallus	96.24	1.00e-106	378.00
IUUC-Gac-041469	Gasterosteus aculeatus	83.47	1.00e-56	211.00
IUUC-Ggo-045282	Gorilla gorilla	99.37	9.00e-162	562.00
IUUC-Hsa-045926	Homo sapiens	96.39	0.00e+00	709.00
IUUC-Itr-048411	Ictidomys tridecemlineatus	95.54	4.00e-168	584.00
IUUC-Lch-049768	Latimeria chalumnae	72.69	8.00e-159	553.00
IUUC-Loc-051949	Lepisosteus oculatus	74.55	2.00e-128	452.00
IUUC-Laf-053410	Loxodonta africana	94.43	0.00e+00	699.00
IUUC-Mcc-054605	Macaca mulatta	89.63	0.00e+00	679.00
IUUC-Meu-056773	Macropus eugenii	79.94	1.00e-105	375.00
IUUC-Mmr-060927	Microcebus murinus	98.08	0.00e+00	715.00
IUUC-Mdo-061892	Monodelphis domestica	88.49	1.00e-178	619.00
IUUC-Mmu-064246	Mus musculus	93.79	0.00e+00	705.00
IUUC-Mpu-065995	Mustela putorius furo	96.62	0.00e+00	641.00
IUUC-Mlu-067526	Myotis lucifugus	92.21	0.00e+00	735.00
IUUC-Nle-069317	Nomascus leucogenys	89.59	4.00e-168	584.00
IUUC-Ont-072258	Oreochromis niloticus	55.01	6.00e-119	421.00
IUUC-Oan-073703	Ornithorhynchus anatinus	80.49	1.00e-36	143.00
IUUC-Ocu-074577	Oryctolagus cuniculus	91.10	0.00e+00	745.00
IUUC-Oga-088426	Otolemur garnettii	96.54	0.00e+00	708.00
IUUC-Oar-089407	Ovis aries	99.37	0.00e+00	688.00
IUUC-Ptr-091327	Pan troglodytes	98.68	0.00e+00	630.00
IUUC-Pan-092064	Papio anubis	98.94	0.00e+00	643.00
IUUC-Psi-093834	Pelodiscus sinensis	94.06	1.00e-152	532.00
IUUC-Pfo-097100	Poecilia formosa	63.13	4.00e-115	409.00
IUUC-Pab-097695	Pongo abelii	88.08	0.00e+00	695.00
IUUC-Pca-100569	Procavia capensis	90.16	2.00e-169	588.00
IUUC-Pva-102784	Pteropus vampyrus	95.68	0.00e+00	702.00
IUUC-Ptt-103775	Puccinia triticina	38.46	1.50e+00	28.50
IUUC-Rno-105485	Rattus norvegicus	94.65	0.00e+00	708.00
IUUC-Sha-106720	Sarcophilus harrisii	93.68	9.00e-172	596.00
IUUC-Sar-112975	Sorex araneus	84.33	3.00e-127	447.00
IUUC-Ssc-116369	Sus scrofa	96.56	0.00e+00	729.00
IUUC-Tgu-116867	Taeniopygia guttata	86.94	3.00e-124	437.00
IUUC-Tru-117562	Takifugu rubripes	81.57	3.00e-101	362.00
IUUC-Tsy-118999	Tarsius syrichta	93.42	4.00e-145	507.00
IUUC-Tni-120793	Tetraodon nigroviridis	60.45	6.00e-131	461.00
IUUC-Tbe-127671	Tupaia belangeri	98.62	2.00e-127	448.00
IUUC-Ttr-128491	Tursiops truncatus	80.51	2.00e-136	479.00
IUUC-Vpa-130104	Vicugna pacos	91.28	9.00e-179	619.00
IUUC-Xtr-132507	Xenopus tropicalis	81.72	5.00e-144	504.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence