iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066699

Ensembl Protein ID

ENSMPUP00000007820.1

UniProt Accession

M3Y913; M3Y913_MUSPF

Genbank Protein ID

ENSMPUP00000007820

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01039104

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000007878.1	ENSMPUT00000007945.1	ENSMPUP00000007820.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-86	290.2	47	363

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           tGl+NlgNtCYmN +LQcL +i++l e++l+ k+  +l+     ++  e++++++ +++ +w ++++ vsp+ + +al+++ + f +  
   Q: 47   TGLRNLGNTCYMNTILQCLGSISPLVEYFLSgKYITALQ-----KECSEVATAFAYVMTDMWLGDSECVSPEIFRSALGNLYPAFMKKT 130
           7******************************44444444.....5677***************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           qqDaqEfl ++l++l+e+l     k++++ ++++k +      +k  ++++s+i++lF+gql  + +cl+c++ + ++e f+ lslp+p
   Q: 131  QQDAQEFLIYVLNELHEAL-----KKYHRRRSSEKGSI-PRCCRKVITSESSIITQLFEGQLNYSFMCLKCESCTFKNEVFTVLSLPIP 213
           *******************.....44666655554444.4557999******************************************* PP
   S: 178  gkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfc 265
           ++ e+   slqdcL+ f+++++l  +n+++c+ c+ kqe+  + +++k P+++i+hLkRf  +  + +++k+ + +++pl+ Ldl+p+ 
   Q: 214  SEYEC---SLQDCLQCFFQQDTLAWNNQIHCSFCETKQETAVRASISKAPKIIIFHLKRF--DILGTMKRKLRTDIHYPLTnLDLTPYI 297
           *****...****************************************************..55668999******************* PP
   S: 266  tspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           +   +k   + kY+L+avv+H G l++GHY+a++kn+  + W+ fdD++V+e++ ++v++   +taY+lfY 
   Q: 298  CPVFRK---HPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQaWYSFDDTRVSEIPDTSVQT---ATAYLLFYS 363
           *95544...89*************************98888*******************...********6 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

LTTMTSRRPL PADDFSIYYV LAECTDHYDN CPVNEAEENQ PHFQGVTGLR NLGNTCYMNT 60
ILQCLGSISP LVEYFLSGKY ITALQKECSE VATAFAYVMT DMWLGDSECV SPEIFRSALG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAGGGGA GAGGGAGAGA GAGAACCACA AGCAGCCTTC ACACTAGCAC GGAGCCCAAT 60
GCAGAACTCG ATCTCACAAC CCTGAGATCA TGACCTCAAC CAGATGCTCA GCCAGCCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	93.35	0.00e+00	740.00
IUUC-Aca-005256	Anolis carolinensis	48.70	2.00e-101	362.00
IUUC-Bta-012753	Bos taurus	84.99	0.00e+00	667.00
IUUC-Cfa-020054	Canis familiaris	89.52	3.00e-180	624.00
IUUC-Cpo-021375	Cavia porcellus	77.56	8.00e-166	576.00
IUUC-Csa-023902	Chlorocebus sabaeus	84.55	2.00e-107	381.00
IUUC-Cho-024755	Choloepus hoffmanni	75.15	2.00e-146	511.00
IUUC-Dor-030311	Dipodomys ordii	85.95	9.00e-94	336.00
IUUC-Ete-032570	Echinops telfairi	64.38	8.00e-105	373.00
IUUC-Eca-034343	Equus caballus	89.89	0.00e+00	712.00
IUUC-Eeu-034510	Erinaceus europaeus	88.40	3.00e-171	593.00
IUUC-Fca-035920	Felis catus	91.15	0.00e+00	714.00
IUUC-Fal-036903	Ficedula albicollis	56.25	2.00e-106	378.00
IUUC-Gac-042261	Gasterosteus aculeatus	42.43	8.00e-71	260.00
IUUC-Hsa-046665	Homo sapiens	82.51	2.00e-166	578.00
IUUC-Itr-048167	Ictidomys tridecemlineatus	90.35	0.00e+00	715.00
IUUC-Lch-049925	Latimeria chalumnae	53.47	3.00e-104	371.00
IUUC-Loc-051880	Lepisosteus oculatus	49.01	5.00e-81	295.00
IUUC-Laf-054494	Loxodonta africana	89.92	0.00e+00	697.00
IUUC-Mcc-055507	Macaca mulatta	88.57	0.00e+00	648.00
IUUC-Meu-055906	Macropus eugenii	74.77	2.00e-151	528.00
IUUC-Mmr-061564	Microcebus murinus	63.91	3.00e-111	394.00
IUUC-Mdo-061800	Monodelphis domestica	77.42	1.00e-175	608.00
IUUC-Mmu-063618	Mus musculus	82.57	0.00e+00	640.00
IUUC-Mlu-067672	Myotis lucifugus	87.70	0.00e+00	692.00
IUUC-Opr-070949	Ochotona princeps	82.86	6.00e-155	539.00
IUUC-Oan-073725	Ornithorhynchus anatinus	64.25	9.00e-144	503.00
IUUC-Ocu-074021	Oryctolagus cuniculus	91.13	0.00e+00	723.00
IUUC-Oga-088258	Otolemur garnettii	87.00	8.00e-170	589.00
IUUC-Oar-089881	Ovis aries	88.20	0.00e+00	698.00
IUUC-Ptr-090988	Pan troglodytes	82.69	2.00e-161	561.00
IUUC-Pan-091773	Papio anubis	88.17	0.00e+00	682.00
IUUC-Psi-093243	Pelodiscus sinensis	72.96	5.00e-139	486.00
IUUC-Pab-097713	Pongo abelii	84.14	3.00e-178	617.00
IUUC-Pca-100226	Procavia capensis	68.34	2.00e-134	471.00
IUUC-Pva-103172	Pteropus vampyrus	89.64	0.00e+00	639.00
IUUC-Rno-105950	Rattus norvegicus	83.91	0.00e+00	653.00
IUUC-Sha-107026	Sarcophilus harrisii	75.54	1.00e-169	588.00
IUUC-Ssc-116383	Sus scrofa	91.76	0.00e+00	727.00
IUUC-Tgu-116511	Taeniopygia guttata	54.90	2.00e-98	352.00
IUUC-Tbe-127808	Tupaia belangeri	82.48	1.00e-62	233.00
IUUC-Ttr-129046	Tursiops truncatus	86.09	1.00e-174	605.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence