iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125321

Ensembl Protein ID

TRIAE_CS42_6DS_TGACv1_542583_AA1724790.1

UniProt Accession

A0A1D6BC39; A0A1D6BC39_WHEAT

Protein Name

Coatomer subunit beta'

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_6DS_TGACv1_542583_AA1724790	TRIAE_CS42_6DS_TGACv1_542583_AA1724790.1	TRIAE_CS42_6DS_TGACv1_542583_AA1724790.1
TRIAE_CS42_6DS_TGACv1_542583_AA1724790	TRIAE_CS42_6DS_TGACv1_542583_AA1724790.3	TRIAE_CS42_6DS_TGACv1_542583_AA1724790.3
TRIAE_CS42_6DS_TGACv1_542583_AA1724790	TRIAE_CS42_6DS_TGACv1_542583_AA1724790.4	TRIAE_CS42_6DS_TGACv1_542583_AA1724790.4
TRIAE_CS42_6DS_TGACv1_542583_AA1724790	TRIAE_CS42_6DS_TGACv1_542583_AA1724790.7	TRIAE_CS42_6DS_TGACv1_542583_AA1724790.7
TRIAE_CS42_6DS_TGACv1_542583_AA1724790	TRIAE_CS42_6DS_TGACv1_542583_AA1724790.8	TRIAE_CS42_6DS_TGACv1_542583_AA1724790.8

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.00e-31	108.3	183	224
UBD/Beta-Prp	1.00e-64	221.3	14	288

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 183  GHSKGVNCVDYftgGDrPFLITGSDDQTAKVWDYQTKSCVQT 224
           8********966997789******************999986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtik 77
           +++++++ + +p +++++++ ++g++ +w+++t+++++s++  e +v++ kf+ ++++ v g++D++i+
   Q: 14   RSERVKSADLHPTEPWILSSLYSGSVCIWNYQTQTMVKSFEVTELPVRSAKFIARKQWVVAGADDMFIR 82
           5678899999*********************************************************** PP
   S: 78   vwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvh 146
           v++++t + v ++++h+d++++++++p++ +++s s+d  i++wd+++g+   ++++gh++ v+ v+++
   Q: 83   VYNYNTMDKVKVFEAHTDYIRCVAVHPTQPFVLSSSDDMLIKLWDWDKGWACTHIFEGHSHYVMQVTFN 151
           **************************************************9989*************** PP
   S: 147  pdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklwdlqtg 212
           p++ n ++s+slDrt+++W++ + +   tl g h + v++++     ++++l++gs+d+t k+wd+qt+
   Q: 152  PKDtNTFASASLDRTIKIWSIGSPDPNFTLDG-HSKGVNCVDyfTGGDRPFLITGSDDQTAKVWDYQTK 219
           *******************************9.*********7445566******************** PP
   S: 213  ecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlv 281
           +cv+tl+gh  nv+ v f+p+  ++++gs+Dg++r+W +++  l +tl++  ++v++  +++ ++++++
   Q: 220  SCVQTLEGHAHNVSAVCFHPELPIIITGSEDGTVRLWHSTTYRLENTLNYGLERVWALGYMKGSRRIVI 288
           ********************************************************9998665555553 PP

Organism

Triticum aestivum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLDIKRK LAQRSERVKS ADLHPTEPWI LSSLYSGSVC IWNYQTQTMV KSFEVTELPV 60
RSAKFIARKQ WVVAGADDMF IRVYNYNTMD KVKVFEAHTD YIRCVAVHPT QPFVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACACACGCA CACACACAAC CTTCAGATCC AATCGACCAT ACTACTGCCT CCGAGCGACC 60
GAGACCCCGT TTGCCATCAC CCACTTCCTC CTTCCCACCC TTCCTCCTTC GTTCACAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002154	Ailuropoda melanoleuca	61.39	0.00e+00	1100.00
IUUC-Cel-018387	Caenorhabditis elegans	54.89	0.00e+00	959.00
IUUC-Cja-019145	Callithrix jacchus	61.32	0.00e+00	1100.00
IUUC-Cfa-020564	Canis familiaris	61.44	0.00e+00	1102.00
IUUC-Cho-024454	Choloepus hoffmanni	59.02	0.00e+00	924.00
IUUC-Gga-041112	Gallus gallus	61.14	0.00e+00	1108.00
IUUC-Gac-041733	Gasterosteus aculeatus	59.76	0.00e+00	1056.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	60.66	0.00e+00	1100.00
IUUC-Mcc-054859	Macaca mulatta	61.32	0.00e+00	1100.00
IUUC-Mmr-061261	Microcebus murinus	61.44	0.00e+00	1102.00
IUUC-Mmu-063324	Mus musculus	61.44	0.00e+00	1103.00
IUUC-Opr-070334	Ochotona princeps	62.55	0.00e+00	995.00
IUUC-Ocu-074522	Oryctolagus cuniculus	61.44	0.00e+00	1098.00
IUUC-Oar-089842	Ovis aries	61.20	0.00e+00	1101.00
IUUC-Ptr-090501	Pan troglodytes	60.47	0.00e+00	1100.00
IUUC-Pan-092011	Papio anubis	61.32	0.00e+00	1100.00
IUUC-Psi-093308	Pelodiscus sinensis	60.66	0.00e+00	1103.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence