iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000006352.1	ENSOART00000006907.1	ENSOARP00000006803.1
ENSOARG00000006352.1	ENSOART00000006909.1	ENSOARP00000006805.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.20e-59	192.9	162	200
UBD/Beta-Prp	2.90e-81	273.1	34	246

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H ++v+c +f +d +l+vs+sdD+t+k+WD ++  +++s
   Q: 162  HINWVRCAKFsPDgRLIVSASDDKTVKLWDKTSRECVHS 200
           999********999******************9999886 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           kgh++  +t+v+fs ++++la+gs+d+++ vw +++++   ++ gh+++vt+v+fsp+g +l++gs+D+t+++w ++      ++++h+
   Q: 34   KGHRD-AVTSVDFSLNTKQLASGSMDSCLMVWHMKPQSRAYRFAGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHT 121
           45555.6666****************************************************************7775555567899** PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           ++v+s++f+ +g+++v++s+d+t++vw ++ ++ l   ls+h  +v+c++++pdg+l+vs+s+D+tv+lWd  + ++++   + h + v
   Q: 122  ATVRSVHFCSDGQSFVTASDDKTVKVWSTHRQKFLF-SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECVHSYCE-HGGFV 208
           ***************************999999999.********************************************98.***** PP
   S: 184  yslsfdsngkelvsgsldgtvklwdlqtgecvrtlngh 221
           + ++f+++g++++++++d+tvk+wd++t + ++ ++ h
   Q: 209  TYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLH 246
           ****************************9999988755 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

GSVLDLGKPL PHPGFTHLTL ALPQEDPSLE RHFKGHRDAV TSVDFSLNTK QLASGSMDSC 60
LMVWHMKPQS RAYRFAGHKD AVTCVNFSPS GHLLASGSRD KTVRIWVPNV KGESTVFRAH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCGCGC ACTGCCCGGT AAGTTTCTGT CAGCGGCGGC CGCCCGAGCT GTAGTCTCTC 60
CGCGGGGACA GTGGGACGCG GGGTTCCGAG CAGGTCCTCT CTGGCCCCAG ATTTCGGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000922--C:spindle pole
GO:0003431--P:growth plate cartilage chondrocyte development
GO:0007052--P:mitotic spindle organization
GO:1905515--P:non-motile cilium assembly
GO:0010825--P:positive regulation of centrosome duplication
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001513	Ailuropoda melanoleuca	94.40	0.00e+00	770.00
IUUC-Apl-003466	Anas platyrhynchos	80.00	0.00e+00	651.00
IUUC-Aca-004323	Anolis carolinensis	72.31	1.00e-180	625.00
IUUC-Bta-012484	Bos taurus	98.50	0.00e+00	823.00
IUUC-Cja-019067	Callithrix jacchus	91.36	0.00e+00	788.00
IUUC-Cfa-020439	Canis familiaris	94.26	0.00e+00	763.00
IUUC-Cpo-021403	Cavia porcellus	89.02	0.00e+00	767.00
IUUC-Cre-022724	Chlamydomonas reinhardtii	51.91	1.00e-113	402.00
IUUC-Csa-023479	Chlorocebus sabaeus	92.68	0.00e+00	688.00
IUUC-Cho-024354	Choloepus hoffmanni	88.18	2.00e-114	404.00
IUUC-Cin-025258	Ciona intestinalis	72.73	9.00e-144	503.00
IUUC-Csv-025955	Ciona savignyi	63.32	2.00e-144	504.00
IUUC-Dno-029467	Dasypus novemcinctus	78.40	3.00e-126	444.00
IUUC-Dor-030399	Dipodomys ordii	88.21	0.00e+00	739.00
IUUC-Dme-032182	Drosophila melanogaster	46.67	1.00e-80	293.00
IUUC-Eca-034425	Equus caballus	93.65	0.00e+00	791.00
IUUC-Eeu-034607	Erinaceus europaeus	79.85	0.00e+00	625.00
IUUC-Fca-035627	Felis catus	95.01	0.00e+00	764.00
IUUC-Fal-037381	Ficedula albicollis	76.05	0.00e+00	632.00
IUUC-Gmo-038489	Gadus morhua	67.59	4.00e-161	560.00
IUUC-Gga-040559	Gallus gallus	75.63	1.00e-178	618.00
IUUC-Gac-041453	Gasterosteus aculeatus	69.61	9.00e-169	586.00
IUUC-Ggo-044773	Gorilla gorilla	92.38	0.00e+00	746.00
IUUC-Hsa-045823	Homo sapiens	92.87	0.00e+00	751.00
IUUC-Itr-048560	Ictidomys tridecemlineatus	91.29	0.00e+00	758.00
IUUC-Lch-050558	Latimeria chalumnae	68.98	2.00e-175	608.00
IUUC-Loc-052836	Lepisosteus oculatus	69.52	2.00e-177	615.00
IUUC-Laf-053974	Loxodonta africana	83.86	0.00e+00	662.00
IUUC-Mcc-055494	Macaca mulatta	90.67	0.00e+00	753.00
IUUC-Meu-056646	Macropus eugenii	75.17	6.00e-129	453.00
IUUC-Mga-059295	Meleagris gallopavo	68.54	3.00e-174	604.00
IUUC-Mmr-061040	Microcebus murinus	93.52	0.00e+00	762.00
IUUC-Mdo-062519	Monodelphis domestica	79.19	3.00e-176	610.00
IUUC-Mmu-063759	Mus musculus	94.00	5.00e-172	597.00
IUUC-Mpu-066442	Mustela putorius furo	94.76	0.00e+00	763.00
IUUC-Mlu-068163	Myotis lucifugus	91.08	0.00e+00	759.00
IUUC-Nle-070160	Nomascus leucogenys	92.77	0.00e+00	747.00
IUUC-Opr-070192	Ochotona princeps	89.52	0.00e+00	671.00
IUUC-Ont-072539	Oreochromis niloticus	76.55	3.00e-150	525.00
IUUC-Oan-072834	Ornithorhynchus anatinus	61.59	1.00e-113	402.00
IUUC-Ocu-074624	Oryctolagus cuniculus	91.33	0.00e+00	690.00
IUUC-Ola-087268	Oryzias latipes	61.94	1.00e-159	556.00
IUUC-Oga-088964	Otolemur garnettii	86.06	0.00e+00	711.00
IUUC-Ptr-091164	Pan troglodytes	93.53	0.00e+00	752.00
IUUC-Pan-092805	Papio anubis	92.14	0.00e+00	683.00
IUUC-Psi-093359	Pelodiscus sinensis	86.13	3.00e-166	577.00
IUUC-Pma-094425	Petromyzon marinus	64.33	4.00e-166	577.00
IUUC-Ppa-095677	Physcomitrella patens	46.25	9.00e-82	296.00
IUUC-Pfo-096741	Poecilia formosa	73.99	5.00e-141	494.00
IUUC-Pab-098376	Pongo abelii	93.52	0.00e+00	767.00
IUUC-Pca-101122	Procavia capensis	88.45	0.00e+00	729.00
IUUC-Pva-103104	Pteropus vampyrus	73.57	5.00e-166	577.00
IUUC-Rno-105282	Rattus norvegicus	87.30	0.00e+00	651.00
IUUC-Sha-106840	Sarcophilus harrisii	82.50	1.00e-119	421.00
IUUC-Smo-108731	Selaginella moellendorffii	44.76	5.00e-79	287.00
IUUC-Sar-113262	Sorex araneus	64.59	5.00e-137	480.00
IUUC-Ssc-115392	Sus scrofa	93.50	0.00e+00	691.00
IUUC-Tgu-117340	Taeniopygia guttata	75.00	2.00e-176	611.00
IUUC-Tru-117577	Takifugu rubripes	72.52	2.00e-137	481.00
IUUC-Tsy-119404	Tarsius syrichta	85.79	0.00e+00	698.00
IUUC-Tni-120713	Tetraodon nigroviridis	70.38	2.00e-137	482.00
IUUC-Tbe-127788	Tupaia belangeri	72.85	2.00e-149	521.00
IUUC-Ttr-128608	Tursiops truncatus	90.02	0.00e+00	716.00
IUUC-Xtr-132720	Xenopus tropicalis	63.06	1.00e-159	555.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence