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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063219
UUCD1 version UUC-MuM-00838
Ensembl Protein ID ENSMUSP00000016383.3
UniProt Accession Q9D4H7; LONF3_MOUSE
Genbank Protein ID BAB30284.1; CAC42191.1; AAI20689.1; AAI20691.1
Protein Name LON peptidase N-terminal domain and RING finger protein 3; RING finger protein 127
Genbank Nucleotide ID AK016522; AL450395; BC120688; BC120690
Gene Name Lonrf3; Rnf127
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000016239.11 ENSMUST00000016383.9 ENSMUSP00000016383.3
ENSMUSG00000016239.11 ENSMUST00000126147.1 ENSMUSP00000118175.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDiRefIndexPINA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 8.50e-10 39.7 458 525
E3 activity/RING/RING 1.30e-06 29.9 461 499
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqpl....teedlvPnltlrrliqawc 69
           ++ C++ + l+ +Pv++p+G+t+  +++e++l+++ k cP+++  l     +++   n  l +li  ++
   Q: 458  DLECSLCMRLFYEPVTTPCGHTFCLKCLERCLDHNAK-CPLCKDVLlqclPSRKYSKNVILEELIATFL 525
           678*********************************9.****987755547778888888888887776 PP
   

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+  f + p+++pCgH+f+++Cl++          +++CPlC+
   Q: 461  CSLCMRLFYE-PVTTPCGHTFCLKCLERC------LDHNAKCPLCK 499
           ****999977.***************999......9*********7 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MDSLQTAQMV SLSAELGSNN LELAEPEEPG TSAAAGQSAA HPEEVTPEGS QALGAQEPEQ 60
SLPLAVPTPL ECKVLLTQAD ALASEGHLRE ALEVYRQLSE RQQLVAEQLE QLVRCLADSV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063219|E3,U-box;E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTGGTAGGAG TCACGTGGTT GCGTTTTATA TAACGCTTCG CTGAGACAAG ACAGTTATTA 60
GGCAGCGCGG GGCAGCCGGC ATGGAGCTCG GGAGGCGAGG CAGACTCGCG CGCGCGGCGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063219|E3,U-box;E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51787--LON_N
PS50005--TPR
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF02190--LON_substr_bdg
PF13445--zf-RING_UBOX
SMART

SM00464--LON
SM00184--RING
SM00028--TPR
Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
KEGG mmu:74365
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001774 Ailuropoda melanoleuca 73.21 0.00e+00 957.00
IUUC-Apl-003916 Anas platyrhynchos 58.73 3.00e-177 614.00
IUUC-Ame-010750 Astyanax mexicanus 43.99 1.00e-158 553.00
IUUC-Bta-012872 Bos taurus 79.87 0.00e+00 1084.00
IUUC-Cja-018747 Callithrix jacchus 73.59 0.00e+00 949.00
IUUC-Cfa-020101 Canis familiaris 78.80 0.00e+00 1053.00
IUUC-Cpo-022041 Cavia porcellus 71.78 0.00e+00 973.00
IUUC-Csa-024034 Chlorocebus sabaeus 79.71 0.00e+00 1089.00
IUUC-Cin-025668 Ciona intestinalis 31.54 1.00e-83 304.00
IUUC-Csv-026364 Ciona savignyi 46.20 2.00e-79 289.00
IUUC-Dno-029518 Dasypus novemcinctus 72.19 0.00e+00 972.00
IUUC-Dor-031132 Dipodomys ordii 68.76 0.00e+00 981.00
IUUC-Dse-031331 Dothistroma septosporum 31.06 4.00e-37 149.00
IUUC-Eca-033382 Equus caballus 81.81 0.00e+00 1130.00
IUUC-Fca-035777 Felis catus 75.00 0.00e+00 699.00
IUUC-Fal-036730 Ficedula albicollis 59.06 0.00e+00 632.00
IUUC-Gmo-039110 Gadus morhua 48.68 1.00e-173 603.00
IUUC-Gga-041187 Gallus gallus 57.01 0.00e+00 798.00
IUUC-Gac-042201 Gasterosteus aculeatus 50.44 0.00e+00 646.00
IUUC-Ggo-045111 Gorilla gorilla 79.84 0.00e+00 1090.00
IUUC-Hsa-045695 Homo sapiens 79.84 0.00e+00 1088.00
IUUC-Lch-050429 Latimeria chalumnae 51.35 0.00e+00 718.00
IUUC-Loc-051922 Lepisosteus oculatus 45.48 2.00e-170 592.00
IUUC-Lma-053145 Leptosphaeria maculans 31.25 8.00e-40 158.00
IUUC-Laf-053434 Loxodonta africana 82.19 0.00e+00 855.00
IUUC-Mcc-055249 Macaca mulatta 75.55 0.00e+00 719.00
IUUC-Mga-060131 Meleagris gallopavo 60.97 2.00e-175 608.00
IUUC-Mmr-060749 Microcebus murinus 81.05 0.00e+00 1125.00
IUUC-Mdo-062261 Monodelphis domestica 55.03 0.00e+00 743.00
IUUC-Mpu-066222 Mustela putorius furo 73.31 0.00e+00 961.00
IUUC-Mlu-067769 Myotis lucifugus 75.69 0.00e+00 1034.00
IUUC-Nle-069738 Nomascus leucogenys 84.99 0.00e+00 921.00
IUUC-Ont-072029 Oreochromis niloticus 57.01 1.00e-171 596.00
IUUC-Oan-073179 Ornithorhynchus anatinus 60.62 5.00e-175 607.00
IUUC-Ocu-074884 Oryctolagus cuniculus 78.01 0.00e+00 1028.00
IUUC-Oga-089109 Otolemur garnettii 78.76 0.00e+00 1066.00
IUUC-Oar-089903 Ovis aries 79.74 0.00e+00 1090.00
IUUC-Ptr-091238 Pan troglodytes 79.27 0.00e+00 1075.00
IUUC-Pan-092379 Papio anubis 74.75 0.00e+00 1074.00
IUUC-Psi-093418 Pelodiscus sinensis 59.57 0.00e+00 699.00
IUUC-Pma-094231 Petromyzon marinus 63.24 7.00e-109 386.00
IUUC-Pno-094889 Phaeosphaeria nodorum 39.15 1.00e-40 160.00
IUUC-Pfo-097284 Poecilia formosa 49.50 4.00e-179 621.00
IUUC-Pab-098343 Pongo abelii 74.75 0.00e+00 1065.00
IUUC-Pca-100905 Procavia capensis 76.07 0.00e+00 923.00
IUUC-Pva-102242 Pteropus vampyrus 75.69 0.00e+00 1016.00
IUUC-Ptt-103898 Puccinia triticina 26.44 2.00e-29 124.00
IUUC-Pte-104214 Pyrenophora teres 31.90 4.00e-38 152.00
IUUC-Pyt-104565 Pyrenophora triticirepentis 32.21 4.00e-38 152.00
IUUC-Rno-105899 Rattus norvegicus 84.69 0.00e+00 1210.00
IUUC-Sha-107565 Sarcophilus harrisii 50.07 0.00e+00 664.00
IUUC-Sja-107742 Schizosaccharomyces japonicus 36.41 8.00e-31 128.00
IUUC-Sar-112999 Sorex araneus 60.39 0.00e+00 652.00
IUUC-Ssc-115705 Sus scrofa 81.58 0.00e+00 1102.00
IUUC-Tgu-116978 Taeniopygia guttata 63.19 0.00e+00 775.00
IUUC-Tsy-118988 Tarsius syrichta 86.80 0.00e+00 886.00
IUUC-Tni-119913 Tetraodon nigroviridis 46.84 2.00e-156 546.00
IUUC-Tca-121632 Theobroma cacao 34.88 5.00e-44 172.00
IUUC-Tbe-127563 Tupaia belangeri 66.50 3.00e-138 484.00
IUUC-Ttr-128875 Tursiops truncatus 80.24 0.00e+00 1036.00
IUUC-Vpa-130779 Vicugna pacos 93.73 5.00e-158 550.00
IUUC-Xtr-132508 Xenopus tropicalis 50.79 0.00e+00 696.00
Created Date 25-Jun-2017

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