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Tag Content
UUCD2 ID IUUC-Nle-069285
UUCD1 version UUC-NoL-00392
Ensembl Protein ID ENSNLEP00000009017.1
UniProt Accession G1R745; G1R745_NOMLE
Genbank Protein ID ENSNLEP00000009017
Protein Name Uncharacterized protein
Genbank Nucleotide ID ADFV01057085
Gene Name CBL
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSNLEG00000007392.2 ENSNLET00000009441.2 ENSNLEP00000009017.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 1.90e-07 31.5 381 420
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl  w    + +s  + CP Cr
   Q: 381  CKICAENDKD-VKIEPCGHLMCTSCLTSW----Q-ESEGQGCPFCR 420
           99********.******************....5.555555****8 PP
   
Organism Nomascus leucogenys
Protein Sequence
(Fasta)
MAGNVKKSSG AGGGGGSGGS GSGGLIGLMK DAFQPHHHHH HHLSPHPPGT VDKKMVEKCW 60
KLMDKVVRLC QNPKLALKNS PPYILDLLPD TYQHLRTILS RYEGKMETLG ENEYFRVFME 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Nle-069285|E3,RING|Nomascus leucogenys
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATCGCTCGCA GTCGAGCCGA GCCGGCGGAA CCCGCCTGGG CTCCGACCCT GCCCAGGCCA 60
TGGCCGGCAA CGTGAAGAAG AGCTCTGGGG CCGGGGGCGG CGGCGGCTCC GGGGGCTCGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Nle-069285|E3,RING|Nomascus leucogenys
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR009060--UBA-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3
PF00627--UBA
SMART

SM00184--RING
SM00165--UBA
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0043066--P:negative regulation of apoptotic process
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0048260--P:positive regulation of receptor-mediated endocytosis
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002357 Ailuropoda melanoleuca 89.07 0.00e+00 1411.00
IUUC-Apl-004041 Anas platyrhynchos 82.42 0.00e+00 1293.00
IUUC-Aca-004899 Anolis carolinensis 79.67 0.00e+00 1217.00
IUUC-Ame-011919 Astyanax mexicanus 83.47 0.00e+00 674.00
IUUC-Bta-012759 Bos taurus 89.59 0.00e+00 1438.00
IUUC-Cel-018674 Caenorhabditis elegans 54.90 5.00e-133 468.00
IUUC-Cja-019207 Callithrix jacchus 94.40 0.00e+00 1523.00
IUUC-Cfa-020897 Canis familiaris 90.31 0.00e+00 1434.00
IUUC-Cpo-021453 Cavia porcellus 88.50 0.00e+00 1420.00
IUUC-Csa-023136 Chlorocebus sabaeus 95.38 0.00e+00 1523.00
IUUC-Cho-024282 Choloepus hoffmanni 82.93 0.00e+00 1170.00
IUUC-Cin-025574 Ciona intestinalis 71.54 3.00e-177 614.00
IUUC-Csv-025938 Ciona savignyi 69.87 1.00e-172 598.00
IUUC-Dre-027644 Danio rerio 66.74 0.00e+00 971.00
IUUC-Dno-030025 Dasypus novemcinctus 90.28 0.00e+00 1391.00
IUUC-Dor-031040 Dipodomys ordii 73.67 2.00e-175 609.00
IUUC-Dme-032213 Drosophila melanogaster 74.81 0.00e+00 642.00
IUUC-Ete-033118 Echinops telfairi 84.35 3.00e-135 475.00
IUUC-Eca-033900 Equus caballus 91.46 0.00e+00 1420.00
IUUC-Eeu-035142 Erinaceus europaeus 85.74 0.00e+00 956.00
IUUC-Fca-035455 Felis catus 91.31 0.00e+00 1462.00
IUUC-Fal-037182 Ficedula albicollis 95.02 0.00e+00 901.00
IUUC-Gmo-038698 Gadus morhua 87.30 0.00e+00 868.00
IUUC-Gga-040438 Gallus gallus 81.58 0.00e+00 1322.00
IUUC-Gac-042166 Gasterosteus aculeatus 80.43 0.00e+00 871.00
IUUC-Ggo-045618 Gorilla gorilla 96.26 0.00e+00 1545.00
IUUC-Hsa-046177 Homo sapiens 96.37 0.00e+00 1532.00
IUUC-Itr-048795 Ictidomys tridecemlineatus 96.65 0.00e+00 956.00
IUUC-Lch-050095 Latimeria chalumnae 83.15 0.00e+00 961.00
IUUC-Loc-052570 Lepisosteus oculatus 69.98 0.00e+00 1059.00
IUUC-Laf-054008 Loxodonta africana 88.18 0.00e+00 1439.00
IUUC-Mcc-054676 Macaca mulatta 95.27 0.00e+00 1521.00
IUUC-Meu-056045 Macropus eugenii 57.62 7.00e-156 544.00
IUUC-Mga-059239 Meleagris gallopavo 80.51 0.00e+00 1324.00
IUUC-Mmr-060907 Microcebus murinus 93.50 0.00e+00 1515.00
IUUC-Mdo-062595 Monodelphis domestica 85.50 0.00e+00 1320.00
IUUC-Mmu-063725 Mus musculus 88.67 0.00e+00 1484.00
IUUC-Mpu-066771 Mustela putorius furo 90.05 0.00e+00 1439.00
IUUC-Mlu-067206 Myotis lucifugus 73.95 0.00e+00 1025.00
IUUC-Opr-071026 Ochotona princeps 89.36 0.00e+00 1397.00
IUUC-Ont-071954 Oreochromis niloticus 67.78 0.00e+00 982.00
IUUC-Oan-073165 Ornithorhynchus anatinus 72.53 0.00e+00 741.00
IUUC-Ocu-074657 Oryctolagus cuniculus 89.33 0.00e+00 1362.00
IUUC-Ola-087165 Oryzias latipes 65.32 0.00e+00 988.00
IUUC-Oga-088198 Otolemur garnettii 81.26 0.00e+00 1239.00
IUUC-Oar-090258 Ovis aries 88.90 0.00e+00 1370.00
IUUC-Ptr-090710 Pan troglodytes 96.37 0.00e+00 1532.00
IUUC-Pan-092785 Papio anubis 95.27 0.00e+00 1521.00
IUUC-Psi-093317 Pelodiscus sinensis 72.28 0.00e+00 739.00
IUUC-Pma-094249 Petromyzon marinus 73.61 1.00e-122 432.00
IUUC-Pfo-096990 Poecilia formosa 90.16 0.00e+00 817.00
IUUC-Pab-098526 Pongo abelii 95.70 0.00e+00 1526.00
IUUC-Pca-100844 Procavia capensis 58.22 4.00e-155 542.00
IUUC-Pva-102352 Pteropus vampyrus 97.28 0.00e+00 894.00
IUUC-Rno-105876 Rattus norvegicus 88.45 0.00e+00 1460.00
IUUC-Sha-107588 Sarcophilus harrisii 83.40 0.00e+00 1144.00
IUUC-Sar-112959 Sorex araneus 88.24 0.00e+00 1395.00
IUUC-Ssc-115261 Sus scrofa 90.31 0.00e+00 1447.00
IUUC-Tgu-116580 Taeniopygia guttata 79.58 0.00e+00 1240.00
IUUC-Tru-118731 Takifugu rubripes 79.20 0.00e+00 897.00
IUUC-Tsy-118982 Tarsius syrichta 82.66 0.00e+00 991.00
IUUC-Tni-120725 Tetraodon nigroviridis 67.35 0.00e+00 967.00
IUUC-Tbe-128018 Tupaia belangeri 95.56 0.00e+00 1108.00
IUUC-Ttr-128927 Tursiops truncatus 91.66 0.00e+00 1494.00
IUUC-Vpa-130369 Vicugna pacos 90.90 0.00e+00 1355.00
IUUC-Xtr-132474 Xenopus tropicalis 71.40 0.00e+00 1083.00
Created Date 25-Jun-2017

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