iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117865

UUCD1 version

UUC-TaR-00169

Ensembl Protein ID

ENSTRUP00000009183.1

UniProt Accession

H2S9V7; H2S9V7_TAKRU

Protein Name

Katanin p80 WD40 repeat-containing subunit B1; p80 katanin

Gene Name

katnb1; LOC101068987; KATNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000003894.1	ENSTRUT00000009237.1	ENSTRUP00000009183.1
ENSTRUG00000003894.1	ENSTRUT00000009238.1	ENSTRUP00000009184.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.90e-48	159.4	145	180
UBD/Beta-Prp	9.20e-62	210.1	15	259

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gHt  v++laf +d + l+s+sdDgt+k+WDl +g+
   Q: 145  GHTQAVRSLAFsPDgKWLASASDDGTVKLWDLMQGK 180
           8***********999*****************9887 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
            +++h+s ++c++  +++++llatg+ d ++ +w v++ +++ sl gh+++v +v+fs +++ +vtgs+ + i+vwd+++ k+v tl+g
   Q: 15   KFEAHSSTVSCLALgKNSGRLLATGGHDCRVNLWAVSKANCIMSLTGHKSPVECVQFSMSEDQIVTGSQSGSIRVWDMEAAKIVKTLTG 103
           578899999999999************************************************************************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           h++s+ sl+f+p + +l+sGs d  i++wd + +  +    +gh+++v++++++pdg+ l+s+s+D+tv+lWdl +gk ++++t+ ht 
   Q: 104  HKSSISSLAFHPFQGFLASGSMDTNIKLWDFRRKGHVF-RYTGHTQAVRSLAFSPDGKWLASASDDGTVKLWDLMQGKTITEFTS-HTA 190
           *******************************9988887.8********************************************9.*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDg.siriW 249
           +v+ ++f++n   l+sgs d+tvklwdl++ +++ +++g t++v++v fsp+++ l+sg+ D   ++ W
   Q: 191  AVNIVQFNPNEYLLASGSSDRTVKLWDLEKFKMISSMEGNTTPVRCVCFSPDGDCLYSGATDCmRVFGW 259
           ************************************************************884145555 PP

Organism

Takifugu rubripes

Functional Description
(View)

Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.

Protein Sequence
(Fasta)

MAAANTTKIS WRLQKFEAHS STVSCLALGK NSGRLLATGG HDCRVNLWAV SKANCIMSLT 60
GHKSPVECVQ FSMSEDQIVT GSQSGSIRVW DMEAAKIVKT LTGHKSSISS LAFHPFQGFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGCTG CAAACACCAC CAAGATATCA TGGCGCCTGC GTGAGTCCTT ACACGGCTTT 60
ACATATGTGA TTGTACCAGA ATGCGGCGGT AACTGTGTCC CCTTCTGTTT GTCTGGACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0051013--P:microtubule severing
GO:0030901--P:midbrain development
GO:0007067--P:mitotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000954	Aegilops tauschii	43.52	5.00e-74	273.00
IUUC-Aml-002187	Ailuropoda melanoleuca	54.40	0.00e+00	703.00
IUUC-Atr-002899	Amborella trichopoda	49.66	1.00e-89	324.00
IUUC-Apl-003305	Anas platyrhynchos	59.32	0.00e+00	767.00
IUUC-Aca-004635	Anolis carolinensis	59.37	0.00e+00	733.00
IUUC-Aly-005711	Arabidopsis lyrata	49.50	6.00e-93	335.00
IUUC-Ath-007323	Arabidopsis thaliana	45.85	2.00e-93	337.00
IUUC-Ame-010870	Astyanax mexicanus	60.29	2.00e-102	365.00
IUUC-Bta-012527	Bos taurus	58.30	0.00e+00	753.00
IUUC-Bdi-014652	Brachypodium distachyon	49.33	5.00e-92	332.00
IUUC-Bol-015242	Brassica oleracea	46.75	2.00e-92	333.00
IUUC-Bra-017390	Brassica rapa	46.75	3.00e-92	333.00
IUUC-Cja-019706	Callithrix jacchus	56.59	0.00e+00	699.00
IUUC-Cfa-020139	Canis familiaris	55.02	6.00e-132	464.00
IUUC-Cpo-021710	Cavia porcellus	58.60	0.00e+00	733.00
IUUC-Cre-022746	Chlamydomonas reinhardtii	41.33	1.00e-68	254.00
IUUC-Csa-023546	Chlorocebus sabaeus	64.18	6.00e-134	471.00
IUUC-Cin-025156	Ciona intestinalis	36.04	1.00e-130	460.00
IUUC-Csv-025962	Ciona savignyi	42.86	2.00e-74	272.00
IUUC-Dre-028215	Danio rerio	64.47	0.00e+00	873.00
IUUC-Dno-029314	Dasypus novemcinctus	63.66	1.00e-143	503.00
IUUC-Dor-030482	Dipodomys ordii	58.86	0.00e+00	753.00
IUUC-Dme-032188	Drosophila melanogaster	36.50	1.00e-62	234.00
IUUC-Ete-032871	Echinops telfairi	31.36	2.00e-32	132.00
IUUC-Eca-034143	Equus caballus	58.31	0.00e+00	733.00
IUUC-Fca-035924	Felis catus	63.18	5.00e-142	498.00
IUUC-Fal-037387	Ficedula albicollis	59.80	0.00e+00	784.00
IUUC-Gmo-038692	Gadus morhua	65.18	1.00e-158	553.00
IUUC-Gga-040597	Gallus gallus	58.86	0.00e+00	796.00
IUUC-Gac-042004	Gasterosteus aculeatus	80.00	0.00e+00	708.00
IUUC-Gma-044134	Glycine max	50.50	7.00e-92	331.00
IUUC-Ggo-044761	Gorilla gorilla	64.18	1.00e-139	490.00
IUUC-Hsa-045698	Homo sapiens	64.18	7.00e-145	507.00
IUUC-Hvu-047649	Hordeum vulgare	48.67	2.00e-91	330.00
IUUC-Itr-048697	Ictidomys tridecemlineatus	59.20	0.00e+00	728.00
IUUC-Lch-049674	Latimeria chalumnae	53.27	0.00e+00	722.00
IUUC-Lpe-051554	Leersia perrieri	50.00	2.00e-93	337.00
IUUC-Loc-052623	Lepisosteus oculatus	65.58	0.00e+00	883.00
IUUC-Laf-054587	Loxodonta africana	61.82	1.00e-151	530.00
IUUC-Mcc-055851	Macaca mulatta	64.18	1.00e-139	490.00
IUUC-Meu-056704	Macropus eugenii	59.03	0.00e+00	800.00
IUUC-Mtr-058053	Medicago truncatula	50.17	5.00e-95	342.00
IUUC-Mga-059608	Meleagris gallopavo	59.39	0.00e+00	794.00
IUUC-Mmr-061154	Microcebus murinus	59.08	0.00e+00	734.00
IUUC-Mdo-062365	Monodelphis domestica	56.86	0.00e+00	744.00
IUUC-Mmu-063754	Mus musculus	59.34	0.00e+00	732.00
IUUC-Mac-064667	Musa acuminata	49.66	4.00e-90	325.00
IUUC-Mpu-066245	Mustela putorius furo	63.43	2.00e-143	503.00
IUUC-Mlu-067692	Myotis lucifugus	63.54	1.00e-140	493.00
IUUC-Nle-070051	Nomascus leucogenys	63.93	2.00e-138	486.00
IUUC-Opr-070855	Ochotona princeps	58.23	0.00e+00	736.00
IUUC-Ont-071883	Oreochromis niloticus	73.94	0.00e+00	1036.00
IUUC-Oan-073293	Ornithorhynchus anatinus	59.54	0.00e+00	700.00
IUUC-Ocu-074644	Oryctolagus cuniculus	59.08	0.00e+00	738.00
IUUC-Oba-075448	Oryza barthii	50.00	8.00e-93	335.00
IUUC-Obr-076385	Oryza brachyantha	49.67	1.00e-92	334.00
IUUC-Ogl-077427	Oryza glaberrima	50.00	6.00e-93	335.00
IUUC-Ogu-078062	Oryza glumaepatula	44.82	4.00e-84	306.00
IUUC-Oin-079811	Oryza indica	49.83	2.00e-90	327.00
IUUC-Olo-080245	Oryza longistaminata	49.83	2.00e-90	327.00
IUUC-Ome-081239	Oryza meridionalis	50.00	2.00e-90	327.00
IUUC-Oni-082640	Oryza nivara	50.00	8.00e-93	335.00
IUUC-Opu-083748	Oryza punctata	50.00	5.00e-93	335.00
IUUC-Oru-084609	Oryza rufipogon	50.00	8.00e-93	335.00
IUUC-Osa-085801	Oryza sativa	45.64	3.00e-85	310.00
IUUC-Ola-087483	Oryzias latipes	67.04	0.00e+00	781.00
IUUC-Oga-087964	Otolemur garnettii	58.66	0.00e+00	746.00
IUUC-Oar-089483	Ovis aries	57.10	0.00e+00	721.00
IUUC-Ptr-091387	Pan troglodytes	64.18	9.00e-145	507.00
IUUC-Pan-092623	Papio anubis	64.18	1.00e-139	490.00
IUUC-Psi-093830	Pelodiscus sinensis	60.37	0.00e+00	781.00
IUUC-Pma-094135	Petromyzon marinus	39.69	6.00e-32	130.00
IUUC-Ppa-095379	Physcomitrella patens	51.03	1.00e-86	314.00
IUUC-Pfo-096755	Poecilia formosa	71.63	0.00e+00	1023.00
IUUC-Pab-097564	Pongo abelii	64.18	2.00e-139	489.00
IUUC-Pop-099149	Populus trichocarpa	50.17	1.00e-94	341.00
IUUC-Pca-100357	Procavia capensis	70.00	8.00e-87	314.00
IUUC-Ppe-101237	Prunus persica	50.50	2.00e-94	340.00
IUUC-Pva-102397	Pteropus vampyrus	56.30	0.00e+00	681.00
IUUC-Rno-105349	Rattus norvegicus	59.57	0.00e+00	755.00
IUUC-Smo-109409	Selaginella moellendorffii	50.17	2.00e-88	320.00
IUUC-Sit-110360	Setaria italica	46.47	2.00e-92	333.00
IUUC-Sly-111307	Solanum lycopersicum	49.50	2.00e-89	323.00
IUUC-Stu-112462	Solanum tuberosum	49.15	3.00e-86	312.00
IUUC-Sar-112953	Sorex araneus	55.70	2.00e-71	263.00
IUUC-Sbi-114389	Sorghum bicolor	44.63	5.00e-84	305.00
IUUC-Ssc-115949	Sus scrofa	56.07	7.00e-154	536.00
IUUC-Tgu-117461	Taeniopygia guttata	58.97	0.00e+00	789.00
IUUC-Tsy-119036	Tarsius syrichta	65.35	1.00e-44	173.00
IUUC-Tni-120903	Tetraodon nigroviridis	83.52	0.00e+00	1157.00
IUUC-Tca-121185	Theobroma cacao	49.17	2.00e-92	334.00
IUUC-Tae-125307	Triticum aestivum	48.40	3.00e-92	333.00
IUUC-Tur-126181	Triticum urartu	44.75	8.00e-83	301.00
IUUC-Tbe-127518	Tupaia belangeri	64.50	4.00e-71	262.00
IUUC-Ttr-128172	Tursiops truncatus	58.45	0.00e+00	728.00
IUUC-Vvi-131489	Vitis vinifera	50.83	3.00e-95	342.00
IUUC-Xtr-132915	Xenopus tropicalis	56.54	0.00e+00	754.00
IUUC-Xma-134133	Xiphophorus maculatus	71.06	0.00e+00	1013.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence