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Tag Content
UUCD2 ID IUUC-Mlu-067921
UUCD1 version UUC-MyL-01164
Ensembl Protein ID ENSMLUP00000013936.2
UniProt Accession G1PS05; G1PS05_MYOLU
Genbank Protein ID ENSMLUP00000013936
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AAPE02026419
Gene Name USP3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000015294.2 ENSMLUT00000015299.2 ENSMLUP00000013936.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 5.90e-95 318.3 132 483
UBD/ZnF/ZnF_UBP 5.20e-26 90.7 4 77
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalk 78
           tGl+NlgNtC+mN++LQ+Lsni+++ ++++e             +++ + +++ +++ +l+++++k + +lw+++++a+sp++l+ +++
   Q: 132  TGLRNLGNTCFMNAILQSLSNIEQFCCYFKElpavelrngktAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVW 220
           7******************************888888777765555555555688889******************************* PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkk....eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs 163
           k+ ++f+gy+qqDa+Ef+++lld+l+ el+      + +p+ +e+     ++ + +++   +  +++++ +F+g l++++ cl c+++s
   Q: 221  KIMPNFRGYQQQDAHEFMRYLLDHLHLELQGgfngVSCSPILQEN-----STLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTES 304
           *****************************6644433333333332.....223445678899999************************ PP
   S: 164  sreepfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeq 243
            +++pfldlsl++p++  +k +         sl+dcL+sft  eel++ + y c kckkkq+++kk++++klP+vL+lhLkRf+++   
   Q: 305  RKFDPFLDLSLDIPSQFRNKRSknqengpvcSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTA-- 391
           **************66655444667899999****************************************************7755.. PP
   S: 244  ksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgsta 330
           + r+k++++vefpl+ Ld++ ++ +pe++  e++ Y+L avv      ++sGHY+ay+ + +g+W++f+Ds+Vt ++e++v++   ++a
   Q: 392  YLRNKVDTYVEFPLRgLDMKCYLLEPENSGPENCLYDLAAVVLRNNiRVGSGHYTAYATH-EGRWFHFNDSTVTLTEEDTVVK---AKA 476
           799*********************************************************.9*********************...*** PP
   S: 331  YvlfYkr 337
           Y+lfY +
   Q: 477  YILFYVE 483
           *****76 PP
   

   UBD/ZnF/ZnF_UBP
   S: 5    vcdktenlWlcLtcgsvgCGRyvegHalkHyeetqhpl................vlslstlsvycYacddyvhr 62
           vc++++++W+cLtc+sv+CGRyv+gHa+kHye++q+pl                ++++s++s+ycY+cdd+v++
   Q: 4    VCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQVPLtnhkksekqdkaqhtvCMDCSSYSTYCYRCDDFVVN 77
           6***********************************************************************85 PP
   
Organism Myotis lucifugus
Protein Sequence
(Fasta)
FLLVCRSNKS PWVCLTCSSV HCGRYVNGHA KKHYEDAQVP LTNHKKSEKQ DKAQHTVCMD 60
CSSYSTYCYR CDDFVVNDTK LGLVQKVREH LQNLENSAFT ADRHRKRKLL ENSSLNSKLL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mlu-067921|DUB,USP;UBD,ZnF_UBP|Myotis lucifugus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTTTATTAG TGTGCCGATC CAACAAAAGC CCCTGGGTCT GTTTGACTTG TTCAAGTGTC 60
CACTGTGGAA GGTAGGTGAC ATTCTTATTA CTTTGCTTCC CTACTTGCAT TCTTCAGTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mlu-067921|DUB,USP;UBD,ZnF_UBP|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0070938--C:contractile ring
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0016578--P:histone deubiquitination
GO:0000278--P:mitotic cell cycle
GO:0031647--P:regulation of protein stability
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001537 Ailuropoda melanoleuca 97.14 0.00e+00 892.00
IUUC-Apl-003358 Anas platyrhynchos 93.70 0.00e+00 896.00
IUUC-Aca-004454 Anolis carolinensis 91.49 0.00e+00 803.00
IUUC-Ame-011544 Astyanax mexicanus 75.36 0.00e+00 687.00
IUUC-Bta-012738 Bos taurus 96.73 0.00e+00 875.00
IUUC-Cel-018186 Caenorhabditis elegans 35.96 7.00e-52 198.00
IUUC-Cja-018893 Callithrix jacchus 96.33 0.00e+00 884.00
IUUC-Cfa-020607 Canis familiaris 97.35 0.00e+00 877.00
IUUC-Cpo-021828 Cavia porcellus 94.49 0.00e+00 855.00
IUUC-Csa-023884 Chlorocebus sabaeus 96.71 0.00e+00 773.00
IUUC-Cho-024863 Choloepus hoffmanni 86.94 0.00e+00 755.00
IUUC-Dre-028452 Danio rerio 72.67 0.00e+00 702.00
IUUC-Dno-029531 Dasypus novemcinctus 95.74 0.00e+00 874.00
IUUC-Dor-030913 Dipodomys ordii 88.92 4.00e-176 610.00
IUUC-Ete-032611 Echinops telfairi 91.63 0.00e+00 814.00
IUUC-Eca-033622 Equus caballus 97.56 0.00e+00 883.00
IUUC-Eeu-035268 Erinaceus europaeus 91.82 0.00e+00 804.00
IUUC-Fca-035801 Felis catus 96.55 0.00e+00 911.00
IUUC-Fal-036749 Ficedula albicollis 93.06 0.00e+00 847.00
IUUC-Gmo-039598 Gadus morhua 76.51 0.00e+00 723.00
IUUC-Gga-040883 Gallus gallus 93.90 0.00e+00 863.00
IUUC-Gac-042235 Gasterosteus aculeatus 76.17 0.00e+00 703.00
IUUC-Ggo-044767 Gorilla gorilla 91.04 0.00e+00 837.00
IUUC-Hsa-046581 Homo sapiens 96.53 0.00e+00 905.00
IUUC-Itr-047898 Ictidomys tridecemlineatus 96.94 0.00e+00 875.00
IUUC-Lch-049732 Latimeria chalumnae 90.00 0.00e+00 860.00
IUUC-Loc-052371 Lepisosteus oculatus 88.16 0.00e+00 848.00
IUUC-Laf-054565 Loxodonta africana 96.94 0.00e+00 874.00
IUUC-Mcc-055522 Macaca mulatta 97.14 0.00e+00 911.00
IUUC-Meu-056754 Macropus eugenii 85.67 1.00e-157 549.00
IUUC-Mga-060095 Meleagris gallopavo 94.66 0.00e+00 637.00
IUUC-Mmr-060839 Microcebus murinus 96.94 0.00e+00 874.00
IUUC-Mdo-062339 Monodelphis domestica 96.09 0.00e+00 755.00
IUUC-Mmu-063638 Mus musculus 94.90 0.00e+00 841.00
IUUC-Mpu-066647 Mustela putorius furo 97.01 0.00e+00 761.00
IUUC-Nle-069752 Nomascus leucogenys 96.94 0.00e+00 910.00
IUUC-Opr-070636 Ochotona princeps 84.46 0.00e+00 723.00
IUUC-Ont-071638 Oreochromis niloticus 75.79 0.00e+00 701.00
IUUC-Oan-073417 Ornithorhynchus anatinus 88.57 0.00e+00 825.00
IUUC-Ocu-074620 Oryctolagus cuniculus 94.69 0.00e+00 857.00
IUUC-Ola-087281 Oryzias latipes 77.65 0.00e+00 629.00
IUUC-Olu-087697 Ostreococcus lucimarinus 39.09 3.00e-46 178.00
IUUC-Oga-088448 Otolemur garnettii 95.92 0.00e+00 900.00
IUUC-Oar-090132 Ovis aries 96.53 0.00e+00 874.00
IUUC-Ptr-090696 Pan troglodytes 96.75 0.00e+00 911.00
IUUC-Pan-092124 Papio anubis 96.73 0.00e+00 905.00
IUUC-Psi-093801 Pelodiscus sinensis 94.71 0.00e+00 746.00
IUUC-Pma-094300 Petromyzon marinus 68.91 6.00e-98 350.00
IUUC-Pfo-096330 Poecilia formosa 77.80 0.00e+00 734.00
IUUC-Pab-098191 Pongo abelii 97.14 0.00e+00 911.00
IUUC-Pca-100341 Procavia capensis 96.63 0.00e+00 661.00
IUUC-Pva-103177 Pteropus vampyrus 96.73 0.00e+00 863.00
IUUC-Rno-105048 Rattus norvegicus 93.50 0.00e+00 825.00
IUUC-Sha-107429 Sarcophilus harrisii 95.52 0.00e+00 868.00
IUUC-Sar-113024 Sorex araneus 94.67 0.00e+00 815.00
IUUC-Ssc-115749 Sus scrofa 96.80 3.00e-151 527.00
IUUC-Tgu-117277 Taeniopygia guttata 92.86 0.00e+00 881.00
IUUC-Tru-117844 Takifugu rubripes 78.00 0.00e+00 734.00
IUUC-Tsy-119456 Tarsius syrichta 93.87 0.00e+00 864.00
IUUC-Tni-120251 Tetraodon nigroviridis 75.51 0.00e+00 750.00
IUUC-Tbe-127423 Tupaia belangeri 89.59 0.00e+00 785.00
IUUC-Ttr-128401 Tursiops truncatus 90.18 0.00e+00 794.00
IUUC-Vpa-130549 Vicugna pacos 87.43 9.00e-163 565.00
IUUC-Xtr-131892 Xenopus tropicalis 82.57 0.00e+00 749.00
Created Date 25-Jun-2017

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