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Tag Content
UUCD2 ID IUUC-Tgu-117277
UUCD1 version UUC-TaG-00970
Ensembl Protein ID ENSTGUP00000003278.1
UniProt Accession H0YYA0; H0YYA0_TAEGU
Genbank Protein ID ENSTGUP00000003278
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID ABQF01049698
Gene Name USP3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSTGUG00000003160.1 ENSTGUT00000003311.1 ENSTGUP00000003278.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.70e-100 336.3 129 480
UBD/ZnF/ZnF_UBP 4.30e-25 87.6 1 74
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalk 78
           tGl+NlgNtC+mN++LQ+Lsni+++ ++++e             +++ + +++ +++ +l+++++k + +lw+++++a+sp++l+ +++
   Q: 129  TGLRNLGNTCFMNAILQSLSNIQQFCCYFKElpavelrngktAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGNQTAFSPESLFYVVW 217
           7******************************888888777765555555555688889******************************* PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           k+ ++f+gy+qqDa+Ef+++lld+l+ el+   n    +   +++s+l + +++   +  +++++ +F+g l++++ cl c+++s +++
   Q: 218  KIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSVILQENSSL-SASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFD 305
           *****************************7644444444444443344.445688899999**************************** PP
   S: 168  pfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
           pfldlsl++p++  +k +         +l+dcL+sft  eel++ + y c kckkkq+++kk++++klP+vL+lhLkRf+++   + r+
   Q: 306  PFLDLSLDIPSQFRNKRTknqesgpmcTLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTA--YLRN 392
           **********66654444667899999****************************************************7755..799* PP
   S: 248  kinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlf 334
           k++++vefpl+ Ld++ ++ +pe++  e++ Y+L+avvvH+G +++sGHY+ay+ + +g+W++f+Ds+Vt ++ee+v +   ++aY+lf
   Q: 393  KVDTYVEFPLRgLDMKCYLLEPENSGPESCLYDLVAVVVHHGsGVGSGHYTAYAAH-EGRWFHFNDSTVTLTDEETVGK---AKAYILF 477
           ********************************************************.9*********************...******* PP
   S: 335  Ykr 337
           Y +
   Q: 478  YVE 480
           *76 PP
   

   UBD/ZnF/ZnF_UBP
   S: 5    vcdktenlWlcLtcgsvgCGRyvegHalkHyeetqhpl................vlslstlsvycYacddyvhr 62
           vc++++++W+cLtc+sv+CGRyv+gHa+kHye++q p+                ++++s++s+ycY+cdd+v++
   Q: 1    VCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPMtnhkktekqekvqhtvCMDCSSYSTYCYRCDDFVVN 74
           6***********************************************************************85 PP
   
Organism Taeniopygia guttata
Protein Sequence
(Fasta)
VCRSNKSPWV CLTCSSVHCG RYVNGHAKKH YEDAQIPMTN HKKTEKQEKV QHTVCMDCSS 60
YSTYCYRCDD FVVNDTKLGL VQKVREHLQN LENSAFTSDR HRKRKLLENS TLNSKLLKVN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Tgu-117277|DUB,USP;UBD,ZnF_UBP|Taeniopygia guttata
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTGTGCCGGT CAAATAAAAG TCCCTGGGTC TGTCTGACGT GTTCGAGTGT CCATTGTGGA 60
AGGTGGGTAC AGTGTTAGTG TGCAAATCTT TTGATCAGAC CTTTATCTTT CTCCATTGTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Tgu-117277|DUB,USP;UBD,ZnF_UBP|Taeniopygia guttata
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0070938--C:contractile ring
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0016578--P:histone deubiquitination
GO:0000278--P:mitotic cell cycle
GO:0031647--P:regulation of protein stability
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001537 Ailuropoda melanoleuca 94.69 0.00e+00 872.00
IUUC-Apl-003358 Anas platyrhynchos 97.35 0.00e+00 908.00
IUUC-Aca-004454 Anolis carolinensis 93.15 0.00e+00 808.00
IUUC-Ame-011544 Astyanax mexicanus 77.48 0.00e+00 688.00
IUUC-Bta-012738 Bos taurus 94.69 0.00e+00 853.00
IUUC-Cel-018186 Caenorhabditis elegans 36.52 4.00e-55 208.00
IUUC-Cja-018893 Callithrix jacchus 94.69 0.00e+00 866.00
IUUC-Cfa-020607 Canis familiaris 94.90 0.00e+00 854.00
IUUC-Cpo-021828 Cavia porcellus 93.27 0.00e+00 841.00
IUUC-Csa-023884 Chlorocebus sabaeus 95.53 0.00e+00 758.00
IUUC-Cho-024863 Choloepus hoffmanni 84.69 0.00e+00 731.00
IUUC-Dre-028452 Danio rerio 73.68 0.00e+00 697.00
IUUC-Dno-029531 Dasypus novemcinctus 94.29 0.00e+00 852.00
IUUC-Dor-030913 Dipodomys ordii 86.53 4.00e-174 603.00
IUUC-Ete-032611 Echinops telfairi 89.39 0.00e+00 805.00
IUUC-Eca-033622 Equus caballus 94.49 0.00e+00 852.00
IUUC-Eeu-035268 Erinaceus europaeus 89.98 0.00e+00 786.00
IUUC-Fca-035801 Felis catus 94.08 0.00e+00 883.00
IUUC-Fal-036749 Ficedula albicollis 98.57 0.00e+00 884.00
IUUC-Gmo-039598 Gadus morhua 78.38 0.00e+00 730.00
IUUC-Gga-040883 Gallus gallus 97.55 0.00e+00 875.00
IUUC-Gac-042235 Gasterosteus aculeatus 77.39 0.00e+00 703.00
IUUC-Ggo-044767 Gorilla gorilla 89.21 0.00e+00 817.00
IUUC-Hsa-046581 Homo sapiens 94.90 0.00e+00 889.00
IUUC-Itr-047898 Ictidomys tridecemlineatus 94.49 0.00e+00 851.00
IUUC-Lch-049732 Latimeria chalumnae 90.00 0.00e+00 848.00
IUUC-Loc-052371 Lepisosteus oculatus 88.78 0.00e+00 838.00
IUUC-Laf-054565 Loxodonta africana 94.29 0.00e+00 850.00
IUUC-Mcc-055522 Macaca mulatta 95.10 0.00e+00 891.00
IUUC-Meu-056754 Macropus eugenii 86.27 1.00e-159 556.00
IUUC-Mga-060095 Meleagris gallopavo 97.33 0.00e+00 650.00
IUUC-Mmr-060839 Microcebus murinus 94.69 0.00e+00 852.00
IUUC-Mdo-062339 Monodelphis domestica 96.55 0.00e+00 752.00
IUUC-Mmu-063638 Mus musculus 94.29 0.00e+00 832.00
IUUC-Mpu-066647 Mustela putorius furo 95.40 0.00e+00 745.00
IUUC-Mlu-067921 Myotis lucifugus 92.86 0.00e+00 865.00
IUUC-Nle-069752 Nomascus leucogenys 95.31 0.00e+00 892.00
IUUC-Opr-070636 Ochotona princeps 84.25 0.00e+00 717.00
IUUC-Ont-071638 Oreochromis niloticus 77.71 0.00e+00 706.00
IUUC-Oan-073417 Ornithorhynchus anatinus 89.80 0.00e+00 826.00
IUUC-Ocu-074620 Oryctolagus cuniculus 93.67 0.00e+00 849.00
IUUC-Ola-087281 Oryzias latipes 79.49 0.00e+00 635.00
IUUC-Olu-087697 Ostreococcus lucimarinus 40.33 5.00e-49 187.00
IUUC-Oga-088448 Otolemur garnettii 94.08 0.00e+00 881.00
IUUC-Oar-090132 Ovis aries 94.49 0.00e+00 852.00
IUUC-Ptr-090696 Pan troglodytes 94.90 0.00e+00 890.00
IUUC-Pan-092124 Papio anubis 94.90 0.00e+00 888.00
IUUC-Psi-093801 Pelodiscus sinensis 96.09 0.00e+00 747.00
IUUC-Pma-094472 Petromyzon marinus 73.13 7.00e-95 339.00
IUUC-Pfo-096330 Poecilia formosa 79.55 0.00e+00 731.00
IUUC-Pab-098191 Pongo abelii 95.10 0.00e+00 891.00
IUUC-Pca-100341 Procavia capensis 92.98 0.00e+00 648.00
IUUC-Pva-103177 Pteropus vampyrus 94.08 0.00e+00 840.00
IUUC-Rno-105048 Rattus norvegicus 92.89 0.00e+00 815.00
IUUC-Sha-107429 Sarcophilus harrisii 96.73 0.00e+00 867.00
IUUC-Sar-113024 Sorex araneus 92.32 0.00e+00 793.00
IUUC-Ssc-115749 Sus scrofa 92.88 7.00e-148 515.00
IUUC-Tru-117844 Takifugu rubripes 78.00 0.00e+00 727.00
IUUC-Tsy-119456 Tarsius syrichta 92.02 0.00e+00 846.00
IUUC-Tni-120251 Tetraodon nigroviridis 75.71 0.00e+00 747.00
IUUC-Tbe-127423 Tupaia belangeri 88.78 0.00e+00 775.00
IUUC-Ttr-128401 Tursiops truncatus 87.93 0.00e+00 771.00
IUUC-Vpa-130549 Vicugna pacos 84.43 4.00e-160 556.00
IUUC-Xtr-131892 Xenopus tropicalis 83.57 0.00e+00 753.00
Created Date 25-Jun-2017

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