iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037205

Ensembl Protein ID

ENSFALP00000004560.1

UniProt Accession

U3JP56; U3JP56_FICAL

Genbank Protein ID

ENSFALP00000004560

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021771

Gene Name

ARHGEF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000004384.1	ENSFALT00000004584.1	ENSFALP00000004560.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.00e-15	57.1	10	64

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL++ kGd+++v     +++gW++g  +l+gk G fP+n+v++++
   Q: 10   VVRAKFNFQQTNEDELSFSKGDIIHVT--RVEEGGWWEG--TLNGKTGWFPSNYVREIK 64
           68999*********************7..999*******..8**************997 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MTDNGNHQLV VRAKFNFQQT NEDELSFSKG DIIHVTRVEE GGWWEGTLNG KTGWFPSNYV 60
REIKSNEKPV SPKSGTLKSP PKGFDTSAIN KSYYNVVLQN ILETENEYAK ELQTMLSNYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTTTGATG CAAATGACCT GTATCAGGGA CAGAATTTCA GCAAAGTTCT TAGCTCTCTT 60
GTGGCTTTAA ATAAGGTGAC TGCAGGTAAG TAGAATGCCC TGTCTTGTGC TGGCTTACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00169--PH
PF00621--RhoGEF
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0000322--C:storage vacuole
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0048041--P:focal adhesion assembly
GO:0007030--P:Golgi organization
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0030032--P:lamellipodium assembly
GO:0043065--P:positive regulation of apoptotic process
GO:0010763--P:positive regulation of fibroblast migration
GO:0060124--P:positive regulation of growth hormone secretion
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0032092--P:positive regulation of protein binding
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:1904424--P:regulation of GTP binding
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001259	Ailuropoda melanoleuca	93.16	0.00e+00	1023.00
IUUC-Aca-004591	Anolis carolinensis	95.32	0.00e+00	1150.00
IUUC-Ame-010759	Astyanax mexicanus	77.40	0.00e+00	1068.00
IUUC-Bgr-012305	Blumeria graminis	41.43	2.00e-11	64.70
IUUC-Bta-013328	Bos taurus	92.91	0.00e+00	1217.00
IUUC-Cja-018742	Callithrix jacchus	93.81	0.00e+00	1034.00
IUUC-Cfa-020756	Canis familiaris	92.25	0.00e+00	978.00
IUUC-Cpo-021284	Cavia porcellus	92.06	0.00e+00	1147.00
IUUC-Csa-023162	Chlorocebus sabaeus	94.61	0.00e+00	1215.00
IUUC-Cho-024736	Choloepus hoffmanni	70.14	9.00e-132	463.00
IUUC-Cin-025535	Ciona intestinalis	40.90	2.00e-95	342.00
IUUC-Cne-026866	Cryptococcus neoformans	56.86	2.00e-13	72.00
IUUC-Dre-028646	Danio rerio	77.48	0.00e+00	1079.00
IUUC-Dno-029461	Dasypus novemcinctus	95.89	0.00e+00	1223.00
IUUC-Dor-030623	Dipodomys ordii	81.11	0.00e+00	851.00
IUUC-Dme-032219	Drosophila melanogaster	46.77	1.00e-104	374.00
IUUC-Ete-032236	Echinops telfairi	77.27	0.00e+00	656.00
IUUC-Eca-034137	Equus caballus	94.75	0.00e+00	1204.00
IUUC-Fca-035742	Felis catus	92.25	0.00e+00	947.00
IUUC-Fox-037757	Fusarium oxysporum	40.28	3.00e-12	67.80
IUUC-Fso-038433	Fusarium solani	40.28	3.00e-12	67.80
IUUC-Gmo-039475	Gadus morhua	68.65	0.00e+00	877.00
IUUC-Gga-040539	Gallus gallus	81.99	0.00e+00	1028.00
IUUC-Gac-042615	Gasterosteus aculeatus	64.02	0.00e+00	796.00
IUUC-Ggo-044470	Gorilla gorilla	88.84	0.00e+00	1134.00
IUUC-Hsa-046398	Homo sapiens	93.81	0.00e+00	1035.00
IUUC-Kpa-049278	Komagataella pastoris	27.20	3.00e-18	87.00
IUUC-Loc-052146	Lepisosteus oculatus	88.51	0.00e+00	1189.00
IUUC-Lma-053273	Leptosphaeria maculans	40.32	4.00e-11	63.90
IUUC-Laf-053891	Loxodonta africana	94.33	0.00e+00	1255.00
IUUC-Mcc-055483	Macaca mulatta	93.65	0.00e+00	1035.00
IUUC-Mga-059410	Meleagris gallopavo	98.16	0.00e+00	1246.00
IUUC-Mmr-060758	Microcebus murinus	93.65	0.00e+00	982.00
IUUC-Mdo-061900	Monodelphis domestica	79.72	0.00e+00	1007.00
IUUC-Mmu-063849	Mus musculus	91.53	0.00e+00	973.00
IUUC-Mpu-065876	Mustela putorius furo	91.53	0.00e+00	967.00
IUUC-Mlu-067970	Myotis lucifugus	94.89	0.00e+00	1208.00
IUUC-Ncr-068791	Neurospora crassa	47.37	5.00e-12	67.00
IUUC-Nle-069685	Nomascus leucogenys	75.46	0.00e+00	1018.00
IUUC-Opr-071132	Ochotona princeps	64.66	0.00e+00	647.00
IUUC-Ont-071815	Oreochromis niloticus	76.49	0.00e+00	1060.00
IUUC-Oan-073057	Ornithorhynchus anatinus	95.46	0.00e+00	1238.00
IUUC-Ola-086663	Oryzias latipes	74.79	0.00e+00	978.00
IUUC-Oga-088103	Otolemur garnettii	93.19	0.00e+00	1148.00
IUUC-Ptr-091162	Pan troglodytes	93.65	0.00e+00	1033.00
IUUC-Pan-092093	Papio anubis	82.91	0.00e+00	1068.00
IUUC-Pma-094261	Petromyzon marinus	66.46	2.00e-125	441.00
IUUC-Pfo-096932	Poecilia formosa	65.73	0.00e+00	877.00
IUUC-Pab-097641	Pongo abelii	93.33	0.00e+00	982.00
IUUC-Pva-102819	Pteropus vampyrus	89.90	0.00e+00	962.00
IUUC-Pte-104123	Pyrenophora teres	42.86	5.00e-11	63.50
IUUC-Rno-106099	Rattus norvegicus	92.34	0.00e+00	1145.00
IUUC-Sha-106845	Sarcophilus harrisii	79.57	0.00e+00	1006.00
IUUC-Sly-111123	Solanum lycopersicum	44.23	1.00e-09	56.60
IUUC-Stu-112434	Solanum tuberosum	44.23	2.00e-09	56.60
IUUC-Ssc-116036	Sus scrofa	91.17	0.00e+00	952.00
IUUC-Tgu-117498	Taeniopygia guttata	100.00	0.00e+00	1272.00
IUUC-Tru-118278	Takifugu rubripes	74.40	0.00e+00	996.00
IUUC-Tsy-118990	Tarsius syrichta	89.71	0.00e+00	798.00
IUUC-Tni-120394	Tetraodon nigroviridis	65.01	0.00e+00	856.00
IUUC-Tre-121917	Trichoderma reesei	45.61	4.00e-12	67.40
IUUC-Tvi-122534	Trichoderma virens	45.61	4.00e-12	67.40
IUUC-Ttr-128922	Tursiops truncatus	88.27	0.00e+00	935.00
IUUC-Xtr-132012	Xenopus tropicalis	86.97	0.00e+00	1078.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence