iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010673

Ensembl Protein ID

ENSAMXP00000002422.1

UniProt Accession

W5K4B1; W5K4B1_ASTMX

Genbank Protein ID

ENSAMXP00000002422

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01103958

Gene Name

USP53

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000002366.1	ENSAMXT00000002422.1	ENSAMXP00000002422.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.10e-24	85.6	31	347

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee...fs 85
           Gl N   +N+C++NS++Q+L+++  +r+ l +  ++ +  +       ++ ++l+ +f+++++s+++a    +l +al+++ +    f+
   Q: 31   GLLNEpgQNSCFLNSAIQVLWQLDIFRRSLRQLPTHYCLGD------SCIFCALKGIFSQFQHSRERALPSDNLRHALAETFKDeqrFQ 113
           55555447************************777777765......69*************999999999998888887654323399 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
                Da E+++ +l++++ ++                     +ae +  ++++++ ++ F ++l +q++c +c+ +s    pf++l  
   Q: 114  LGFMDDAAECFENILQRIHLHI-------------------VPDAETDACTSKSCITHQKFAMTLYEQCVCRSCGASSDPL-PFTELVH 182
           9999******************...................2235678899************************999665.9****** PP
   S: 175  pvpgkeetkke.......slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefp 256
            v+    +++          +d++ +  ++ +  g+ +   ++c ++    +++ +++ Pe+ ++ + +   se+ +  e + +++   
   Q: 183  YVSTTALCQQFferrderLRSDMFGELLQAASTIGDLRNCPSNCGQRI-KIRRVLMNS-PEIVTIGFVWD--SEQSDLTEDVIRSLGP- 266
           **9777665546777774446788888888888888877888888777.566666665.*******9999..6666777777777764. PP
   S: 257  leLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvlfYk 336
            +L+ls    + +++ ++k   +L++++++s      HY+++++++k + W+ fdD +V+ev  k+++v++++     ++ +lfY 
   Q: 267  -HLSLSGLFYRVTDEHAKKSDLQLVGMICYSS----RHYCSFAYHTKSSkWVFFDDATVKEVgtKWKDVVTKCIrghFQPLLLFYS 347
           .577776555555666679***********87....9********77767***********9767899999766888899999996 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MAWVKFFRRP GGNLGKAYQP GSMLSLAPTK GLLNEPGQNS CFLNSAIQVL WQLDIFRRSL 60
RQLPTHYCLG DSCIFCALKG IFSQFQHSRE RALPSDNLRH ALAETFKDEQ RFQLGFMDDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTGGACATT TATTCTATGC CCGATGTGCT CCTGTTTCAA CTTCTGAGAA ATGGATGACC 60
CTTTGAAAGG CATTTGGTTT CTGCTGCTGT TCCACACAAG TGCTTAAGCT GTACCCAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002136	Ailuropoda melanoleuca	71.86	0.00e+00	651.00
IUUC-Atr-002451	Amborella trichopoda	32.74	2.00e-42	168.00
IUUC-Aca-004689	Anolis carolinensis	71.46	0.00e+00	645.00
IUUC-Aly-005859	Arabidopsis lyrata	31.29	1.00e-41	165.00
IUUC-Bta-012434	Bos taurus	71.40	0.00e+00	654.00
IUUC-Cfa-020038	Canis familiaris	72.09	0.00e+00	654.00
IUUC-Cpo-021503	Cavia porcellus	71.16	0.00e+00	650.00
IUUC-Cho-024769	Choloepus hoffmanni	63.11	1.00e-157	550.00
IUUC-Dno-029317	Dasypus novemcinctus	71.53	0.00e+00	651.00
IUUC-Dor-030249	Dipodomys ordii	79.06	0.00e+00	635.00
IUUC-Eca-033216	Equus caballus	72.16	0.00e+00	653.00
IUUC-Eeu-035319	Erinaceus europaeus	59.50	5.00e-122	432.00
IUUC-Fca-036414	Felis catus	72.09	0.00e+00	657.00
IUUC-Gmo-039688	Gadus morhua	83.11	0.00e+00	630.00
IUUC-Gac-041515	Gasterosteus aculeatus	86.02	0.00e+00	676.00
IUUC-Gma-043273	Glycine max	31.99	1.00e-40	162.00
IUUC-Ggo-045573	Gorilla gorilla	70.47	0.00e+00	639.00
IUUC-Itr-048229	Ictidomys tridecemlineatus	69.61	0.00e+00	630.00
IUUC-Lch-049932	Latimeria chalumnae	71.66	0.00e+00	655.00
IUUC-Lpe-051572	Leersia perrieri	33.13	2.00e-41	165.00
IUUC-Loc-052180	Lepisosteus oculatus	55.77	0.00e+00	999.00
IUUC-Laf-054545	Loxodonta africana	71.69	0.00e+00	656.00
IUUC-Meu-056802	Macropus eugenii	63.45	3.00e-160	559.00
IUUC-Mtr-058682	Medicago truncatula	29.51	2.00e-35	145.00
IUUC-Mmr-061644	Microcebus murinus	78.61	1.00e-161	562.00
IUUC-Mdo-062636	Monodelphis domestica	70.28	0.00e+00	643.00
IUUC-Mmu-063910	Mus musculus	69.61	2.00e-179	623.00
IUUC-Mpu-065796	Mustela putorius furo	67.05	5.00e-172	598.00
IUUC-Nle-069276	Nomascus leucogenys	69.82	0.00e+00	632.00
IUUC-Ont-072449	Oreochromis niloticus	80.84	0.00e+00	676.00
IUUC-Oba-075174	Oryza barthii	31.45	1.00e-36	149.00
IUUC-Obr-076268	Oryza brachyantha	33.04	3.00e-43	171.00
IUUC-Ogu-078705	Oryza glumaepatula	31.45	9.00e-37	149.00
IUUC-Olo-080872	Oryza longistaminata	31.45	7.00e-37	150.00
IUUC-Ome-081864	Oryza meridionalis	31.45	2.00e-36	149.00
IUUC-Oni-082109	Oryza nivara	31.45	9.00e-37	149.00
IUUC-Oru-084310	Oryza rufipogon	31.45	1.00e-36	149.00
IUUC-Ola-087574	Oryzias latipes	74.81	2.00e-177	614.00
IUUC-Oar-089584	Ovis aries	71.16	0.00e+00	652.00
IUUC-Ptr-091610	Pan troglodytes	70.47	0.00e+00	639.00
IUUC-Pan-091828	Papio anubis	64.04	6.00e-161	561.00
IUUC-Ppa-095930	Physcomitrella patens	32.41	4.00e-41	164.00
IUUC-Pab-098190	Pongo abelii	79.34	0.00e+00	635.00
IUUC-Ppe-101918	Prunus persica	30.79	3.00e-41	164.00
IUUC-Pva-102372	Pteropus vampyrus	68.89	0.00e+00	632.00
IUUC-Sha-107092	Sarcophilus harrisii	71.03	0.00e+00	651.00
IUUC-Sly-110975	Solanum lycopersicum	30.81	5.00e-40	160.00
IUUC-Stu-112904	Solanum tuberosum	31.13	6.00e-38	154.00
IUUC-Sar-113376	Sorex araneus	83.60	3.00e-99	356.00
IUUC-Ssc-115969	Sus scrofa	71.16	0.00e+00	649.00
IUUC-Tru-117981	Takifugu rubripes	78.47	0.00e+00	665.00
IUUC-Tsy-119297	Tarsius syrichta	62.41	3.00e-152	533.00
IUUC-Tni-120116	Tetraodon nigroviridis	85.12	0.00e+00	668.00
IUUC-Tbe-127607	Tupaia belangeri	72.09	0.00e+00	654.00
IUUC-Vpa-130288	Vicugna pacos	64.19	3.00e-158	552.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence