iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000017609.1	ENSONIT00000022223.1	ENSONIP00000022204.1
ENSONIG00000017609.1	ENSONIT00000022224.1	ENSONIP00000022205.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.10e-23	82.9	31	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee...fs 85
           Gl N   +N+C++NS++Q+L+++  +r+ l +   + +        ++++ ++l+++f+++++s++++    +l +al+++ +    f+
   Q: 31   GLLNEpgQNSCFLNSAVQVLWQLDIFRRSLRQLSGHFCLG------DACIFCALKSIFSQFQQSRERVLPSDSLRNALAETFKDeqrFQ 113
           55555447************************77777765......47*************9999888888887777776543322399 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
                Da E+++ +l++++ ++ +                   +   +  ++++++ ++ F + l +q +c  c+ +s    pf++l  
   Q: 114  LGLMDDAAECFENILERIHLHIVS-------------------DTATDSCSSKSCITHQKFAMMLYEQFVCRCCGASSD-PHPFTELVH 182
           **********************22...................2345678999*******************9999885.569****** PP
   S: 175  pvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkve 254
            v+    +++            +d++ +  ++ + +g+ +   ++c ++ + ++   l ++Pe+ ++ + +    e+ +    + ++++
   Q: 183  YVSTTALCQQVdrmlgkserLRSDMFGELLQAANNTGDLRSCPSNCGQSIKIRRV--LMNCPEIVTIGFVWD--AEQSDLTDDVIRSLS 267
           ***8887766688888888544678888888888888888888888887754444..6688******99888..454455555555555 PP
   S: 255  fpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvlfYk 336
            p +L+l    ++ +++++++ +  L++++++       HY a+++++k + W+ fdD +V+e+  k+++v +++     ++ +lfY+
   Q: 268  -P-RLNLCGLFNRVTDENAKRSELHLVGMICFAS----KHYSAFAYHTKSSkWMFFDDATVKEIgsKWKDVASKCIrghFQPLLLFYT 349
           .3.6888886666677777799*********987....9********77767***********9766899999766888999999997 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAWVKMFKKP GGGLKKSYQP GSMLSLALTK GLLNEPGQNS CFLNSAVQVL WQLDIFRRSL 60
RQLSGHFCLG DACIFCALKS IFSQFQQSRE RVLPSDSLRN ALAETFKDEQ RFQLGLMDDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCCATGCA GGGATTGAAG ATTGCAATAC AGCAGCAGTG CACTTGAGGC TACACTAGGG 60
GCGGAGTTTG ACCTCTCAAG TCTCAAAACA TCACTAATCC GCGTCGGACA TTCTGGTACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cre-022697	Chlamydomonas reinhardtii	25.78	7.00e-19	91.30
IUUC-Dor-030249	Dipodomys ordii	74.54	1.00e-175	610.00
IUUC-Eeu-035319	Erinaceus europaeus	55.56	4.00e-115	409.00
IUUC-Gmo-038617	Gadus morhua	91.44	0.00e+00	704.00
IUUC-Gac-041327	Gasterosteus aculeatus	96.68	0.00e+00	741.00
IUUC-Mmr-061644	Microcebus murinus	73.90	1.00e-152	532.00
IUUC-Pfo-096167	Poecilia formosa	95.21	0.00e+00	746.00
IUUC-Sly-110975	Solanum lycopersicum	32.37	2.00e-41	165.00
IUUC-Tru-118240	Takifugu rubripes	86.13	0.00e+00	700.00
IUUC-Tni-119778	Tetraodon nigroviridis	90.43	0.00e+00	677.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence