iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118289

UUCD1 version

UUC-TaR-01058

Ensembl Protein ID

ENSTRUP00000003373.1

UniProt Accession

H2RTA6; H2RTA6_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000001468.1	ENSTRUT00000003392.1	ENSTRUP00000003373.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.70e-30	105.7	1	85

Active Site

Position(s)	Description	Evidence
42	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 41   pYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvllsiqsllaepnpesplneeaaellk 127
           +Y+g  ++l++efp  YP+++P+vkf+t++fhPnv+++G +Cl+ilk  +kWs+ ++v+s llsiqsll epn+espln+ aa+l++
   Q: 1    VYDGLWYRLSLEFPAGYPYQAPRVKFITPCFHPNVDDQGFICLDILK--DKWSALYDVRSLLLSIQSLLGEPNNESPLNAAAAKLWE 85
           599*******************************************9..**********************************9996 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

VYDGLWYRLS LEFPAGYPYQ APRVKFITPC FHPNVDDQGF ICLDILKDKW SALYDVRSLL 60
LSIQSLLGEP NNESPLNAAA AKLWED 86

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTATGATG GTCTCTGGTA CCGGCTGTCT CTGGAGTTTC CAGCTGGTTA CCCATATCAG 60
GCTCCTCGTG TGAAGTTCAT CACACCGTGC TTCCACCCCA ACGTTGACGA TCAGGGTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0000209--P:protein polyubiquitination
GO:0030071--P:regulation of mitotic metaphase/anaphase transition

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001924	Ailuropoda melanoleuca	75.00	3.00e-29	120.00
IUUC-Ame-011302	Astyanax mexicanus	83.72	2.00e-35	141.00
IUUC-Bta-013101	Bos taurus	76.74	9.00e-31	125.00
IUUC-Cfa-020588	Canis familiaris	76.74	9.00e-31	125.00
IUUC-Cpo-021384	Cavia porcellus	76.74	8.00e-31	126.00
IUUC-Csa-023437	Chlorocebus sabaeus	76.74	6.00e-31	126.00
IUUC-Cho-024330	Choloepus hoffmanni	76.74	1.00e-30	124.00
IUUC-Csv-025933	Ciona savignyi	73.81	3.00e-27	114.00
IUUC-Dre-027375	Danio rerio	80.23	2.00e-34	138.00
IUUC-Dno-029921	Dasypus novemcinctus	73.26	6.00e-30	123.00
IUUC-Dme-031942	Drosophila melanogaster	79.07	6.00e-31	126.00
IUUC-Eca-034073	Equus caballus	76.74	9.00e-31	126.00
IUUC-Eeu-034854	Erinaceus europaeus	76.74	1.00e-30	125.00
IUUC-Fca-035666	Felis catus	76.74	9.00e-31	126.00
IUUC-Fal-037652	Ficedula albicollis	72.94	1.00e-29	120.00
IUUC-Gmo-038894	Gadus morhua	84.88	4.00e-36	143.00
IUUC-Gac-041346	Gasterosteus aculeatus	86.05	1.00e-36	145.00
IUUC-Ggo-045594	Gorilla gorilla	73.86	4.00e-29	120.00
IUUC-Hsa-046216	Homo sapiens	75.58	2.00e-30	125.00
IUUC-Itr-048402	Ictidomys tridecemlineatus	76.74	9.00e-31	126.00
IUUC-Lch-049761	Latimeria chalumnae	74.42	2.00e-29	121.00
IUUC-Loc-052297	Lepisosteus oculatus	81.40	7.00e-36	144.00
IUUC-Laf-054468	Loxodonta africana	75.00	1.00e-29	122.00
IUUC-Mcc-055224	Macaca mulatta	76.74	3.00e-31	127.00
IUUC-Meu-056147	Macropus eugenii	76.74	6.00e-31	126.00
IUUC-Mga-059929	Meleagris gallopavo	75.64	2.00e-27	113.00
IUUC-Mmr-060747	Microcebus murinus	76.74	1.00e-30	125.00
IUUC-Mdo-062343	Monodelphis domestica	76.74	7.00e-31	126.00
IUUC-Mmu-063563	Mus musculus	76.74	1.00e-30	125.00
IUUC-Mpu-066541	Mustela putorius furo	75.58	4.00e-30	124.00
IUUC-Mlu-067388	Myotis lucifugus	75.00	3.00e-29	120.00
IUUC-Opr-070902	Ochotona princeps	77.91	3.00e-31	127.00
IUUC-Ont-071672	Oreochromis niloticus	87.21	2.00e-36	144.00
IUUC-Oan-073728	Ornithorhynchus anatinus	75.00	8.00e-24	101.00
IUUC-Ocu-074566	Oryctolagus cuniculus	76.74	1.00e-30	125.00
IUUC-Obr-076757	Oryza brachyantha	72.84	9.00e-27	110.00
IUUC-Ola-086807	Oryzias latipes	84.88	1.00e-36	145.00
IUUC-Oga-089033	Otolemur garnettii	74.42	2.00e-30	124.00
IUUC-Oar-089542	Ovis aries	75.00	3.00e-29	120.00
IUUC-Ptr-091069	Pan troglodytes	75.58	2.00e-30	125.00
IUUC-Pan-092533	Papio anubis	75.00	2.00e-29	122.00
IUUC-Psi-093206	Pelodiscus sinensis	77.91	3.00e-31	126.00
IUUC-Pma-094607	Petromyzon marinus	79.76	6.00e-30	123.00
IUUC-Pfo-096836	Poecilia formosa	86.05	1.00e-36	145.00
IUUC-Pab-098707	Pongo abelii	75.58	2.00e-30	125.00
IUUC-Pca-100661	Procavia capensis	76.74	7.00e-31	126.00
IUUC-Rno-105501	Rattus norvegicus	77.91	4.00e-31	127.00
IUUC-Sha-107205	Sarcophilus harrisii	76.74	1.00e-30	125.00
IUUC-Ssc-115625	Sus scrofa	76.74	9.00e-31	126.00
IUUC-Tni-120070	Tetraodon nigroviridis	93.02	1.00e-38	151.00
IUUC-Tur-126818	Triticum urartu	68.60	1.00e-27	114.00
IUUC-Ttr-128548	Tursiops truncatus	76.74	1.00e-30	125.00
IUUC-Xtr-132953	Xenopus tropicalis	77.01	3.00e-31	127.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence