iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022476

Ensembl Protein ID

ENSCPOP00000020791.1

UniProt Accession

H0WCS0; H0WCS0_CAVPO

Genbank Protein ID

ENSCPOP00000020791

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02051217

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000023584.1	ENSCPOT00000021594.1	ENSCPOP00000020791.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-26	91.2	552	582
UBD/Beta-Prp	1.90e-43	148.8	331	616

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 8    claf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           ++ f +d ++ ++Gs+Dg +++WD++tg+l++
   Q: 552  AV-FsPDrRYALVGSWDGALYIWDVDTGKLEC 582
           33.59999*********************987 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v+f p++sllatg++d+ i +w++  g l   ++++g  + +t+v+++p+g+  + +   +++++w +   +   tl+gh
   Q: 331  DAHLSEVNAVCFGPNSSLLATGGADRLIHLWNAVGGRLeaNQTFEGAGGSITSVDMDPSGSQVLAATYNQAAQLWKVGEAQSKETLSGH 419
           789999********************************888899*****************9999999********************* PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++  ++ +      +++
   Q: 420  KDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TINVLS---YCNDVVCGDHIIISGHNDQKIRFWDSRGPCCTQVIP--VQGR 502
           ************************************9.666655...4555555556****************9999999995..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+s+s+d t+k+ dl+ +++      + +++ +d++k   fsp+  + ++gs Dg ++iWd+++g+l  tl +++  
   Q: 503  VTSLSLSHDQLHLLSCSRDDTLKVIDLRLSNIrqvfrADGFKCGSDWTK-AVFSPDRRYALVGSWDGALYIWDVDTGKLECTLWGPHCA 590
           ****************************777733333455555557766.7899*********************************77 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            +   +++++++++v++++  kv +w
   Q: 591  AVNAVAWCYSGSHVVSVDQGRKVALW 616
           7777778***********99999988 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

GPSVPGAPAA LWKRHIVRQL RQRDRTQKAL FQELVPAYNH LLEKAELLAM FSEKLQLERS 60
NVTSVLHEGS WEESRADSDG VCSPANLKVK WQEEEEALQL VCGEMAYQVV EKSAALATQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGACCGAGCG TCCCGGGCGC CCCCGCCGCC CTCTGGAAAC GCCACATCGT GCGACAGCTG 60
CGGCAGCGGG ATCGCACGCA AAAGGCTCTC TTCCAGGAGC TGGTACCAGC ATGTGAGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	66.24	0.00e+00	738.00
IUUC-Ame-011152	Astyanax mexicanus	41.06	5.00e-117	414.00
IUUC-Bta-013118	Bos taurus	80.68	0.00e+00	882.00
IUUC-Cja-020002	Callithrix jacchus	82.55	0.00e+00	901.00
IUUC-Cfa-020878	Canis familiaris	79.34	0.00e+00	879.00
IUUC-Csa-024134	Chlorocebus sabaeus	82.36	0.00e+00	898.00
IUUC-Cho-024853	Choloepus hoffmanni	67.64	2.00e-178	618.00
IUUC-Dre-027949	Danio rerio	41.42	3.00e-127	448.00
IUUC-Dno-029683	Dasypus novemcinctus	82.58	0.00e+00	778.00
IUUC-Dor-030897	Dipodomys ordii	76.62	0.00e+00	891.00
IUUC-Ete-032957	Echinops telfairi	92.00	1.00e-128	453.00
IUUC-Eca-033303	Equus caballus	89.78	2.00e-162	565.00
IUUC-Eeu-035336	Erinaceus europaeus	71.22	9.00e-148	516.00
IUUC-Fca-036232	Felis catus	82.54	0.00e+00	957.00
IUUC-Gmo-038880	Gadus morhua	49.65	8.00e-68	251.00
IUUC-Ggo-045130	Gorilla gorilla	88.16	0.00e+00	679.00
IUUC-Hsa-046359	Homo sapiens	84.13	0.00e+00	865.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	81.48	0.00e+00	912.00
IUUC-Lch-050669	Latimeria chalumnae	53.17	1.00e-92	332.00
IUUC-Loc-052789	Lepisosteus oculatus	42.58	4.00e-118	418.00
IUUC-Laf-053699	Loxodonta africana	81.72	0.00e+00	889.00
IUUC-Mcc-055657	Macaca mulatta	78.25	0.00e+00	804.00
IUUC-Meu-056639	Macropus eugenii	48.63	9.00e-113	400.00
IUUC-Mmr-061314	Microcebus murinus	74.96	0.00e+00	781.00
IUUC-Mdo-061841	Monodelphis domestica	64.34	0.00e+00	708.00
IUUC-Mmu-064065	Mus musculus	81.38	0.00e+00	916.00
IUUC-Mpu-066742	Mustela putorius furo	81.05	0.00e+00	874.00
IUUC-Mlu-067019	Myotis lucifugus	85.07	0.00e+00	652.00
IUUC-Nle-069037	Nomascus leucogenys	84.30	0.00e+00	911.00
IUUC-Opr-071039	Ochotona princeps	78.41	0.00e+00	872.00
IUUC-Oan-073431	Ornithorhynchus anatinus	71.60	1.00e-137	482.00
IUUC-Ocu-074772	Oryctolagus cuniculus	81.30	0.00e+00	815.00
IUUC-Ola-086964	Oryzias latipes	51.22	9.00e-80	290.00
IUUC-Oga-088188	Otolemur garnettii	81.69	0.00e+00	868.00
IUUC-Oar-090231	Ovis aries	75.65	0.00e+00	870.00
IUUC-Ptr-091434	Pan troglodytes	81.65	0.00e+00	836.00
IUUC-Pan-091868	Papio anubis	83.28	0.00e+00	888.00
IUUC-Psi-093652	Pelodiscus sinensis	62.18	2.00e-157	548.00
IUUC-Pfo-096960	Poecilia formosa	40.98	4.00e-99	355.00
IUUC-Pab-097776	Pongo abelii	83.47	0.00e+00	844.00
IUUC-Pca-100220	Procavia capensis	62.84	5.00e-167	581.00
IUUC-Pva-103135	Pteropus vampyrus	82.33	0.00e+00	842.00
IUUC-Rno-105529	Rattus norvegicus	80.71	0.00e+00	954.00
IUUC-Sha-107062	Sarcophilus harrisii	64.02	0.00e+00	731.00
IUUC-Sar-113109	Sorex araneus	65.86	1.00e-132	466.00
IUUC-Ssc-115271	Sus scrofa	81.39	0.00e+00	860.00
IUUC-Ttr-128267	Tursiops truncatus	79.87	0.00e+00	847.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence