iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092614

Ensembl Protein ID

ENSPANP00000006596.1

UniProt Accession

A0A096N2Q2; A0A096N2Q2_PAPAN

Genbank Protein ID

ENSPANP00000006596

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01012882

Gene Name

UBE2D4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000008000.1	ENSPANT00000006515.1	ENSPANP00000006596.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.00e-55	187.4	5	139
UBD/UBC-like/UBD_UBC	8.30e-82	272.2	6	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R + el++l++dpp+++sa+pv + dl++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+tki+hPn+++nG++Cl+il+  
   Q: 5    RWEAELTDLQRDPPAQCSAGPVGD-DLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR-- 90
           56789*******************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal+v++vllsi+sll++pnp++pl  e+a+++k++re+y++ +r
   Q: 91   SQWSPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAR 139
           *********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 2    ikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqws 90
            + el dl+rd++aq+sa++v+ddlf+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+tkiyhpninsngsicldilrsqws
   Q: 6    WEAELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQWS 94
           5789************************************************************************************* PP
   S: 91   aaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           +alt+skvlls+csll+d++pddplv+eia+ yk+d+eky+r arewt
   Q: 95   PALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAREWT 142
           ***********************************************8 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

FYLRRWEAEL TDLQRDPPAQ CSAGPVGDDL FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTACCTGA GGAGGTGGGA GGCTAGGCTT GGAGGTAAGG CAGAGCTACG TGTGACTGAC 60
TTCTTGCCTG CCCTCTTCCA GCTGTGTACC TTGAGTAGGT AACTTCATCT CTTTACAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008709	Aspergillus flavus	81.88	1.00e-68	254.00
IUUC-Cja-019014	Callithrix jacchus	99.28	6.00e-81	292.00
IUUC-Cpo-021897	Cavia porcellus	96.53	5.00e-81	292.00
IUUC-Csa-023377	Chlorocebus sabaeus	97.20	9.00e-81	292.00
IUUC-Dre-028686	Danio rerio	96.55	3.00e-82	296.00
IUUC-Dor-030323	Dipodomys ordii	96.55	3.00e-82	296.00
IUUC-Eca-033231	Equus caballus	100.00	7.00e-81	291.00
IUUC-Ggo-045361	Gorilla gorilla	97.24	1.00e-82	297.00
IUUC-Hsa-045934	Homo sapiens	97.24	1.00e-82	297.00
IUUC-Loc-052838	Lepisosteus oculatus	97.24	1.00e-82	297.00
IUUC-Mcc-055421	Macaca mulatta	97.24	1.00e-82	297.00
IUUC-Mmr-061446	Microcebus murinus	97.12	4.00e-79	286.00
IUUC-Mdo-062413	Monodelphis domestica	99.28	2.00e-80	290.00
IUUC-Nle-069715	Nomascus leucogenys	97.24	1.00e-82	297.00
IUUC-Ont-072562	Oreochromis niloticus	93.79	2.00e-80	290.00
IUUC-Oan-073026	Ornithorhynchus anatinus	100.00	7.00e-81	292.00
IUUC-Ocu-073914	Oryctolagus cuniculus	97.84	1.00e-79	287.00
IUUC-Ola-087515	Oryzias latipes	94.48	8.00e-81	291.00
IUUC-Pfo-096867	Poecilia formosa	94.48	8.00e-81	291.00
IUUC-Pab-098760	Pongo abelii	96.55	6.00e-82	295.00
IUUC-Ssc-115391	Sus scrofa	97.24	1.00e-82	297.00
IUUC-Tsy-118832	Tarsius syrichta	94.48	1.00e-79	287.00
IUUC-Tbe-128122	Tupaia belangeri	96.77	8.00e-61	224.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence