iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tbe-127586

UUCD1 version

UUC-TuB-00181

Ensembl Protein ID

ENSTBEP00000004262.1

UniProt Accession

A0A077B6F0; A0A077B6F0_TUPBE

Genbank Protein ID

AIL01925.1

Protein Name

TRIM5-2 alpha isoform

Genbank Nucleotide ID

KJ697758

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTBEG00000004960.1	ENSTBET00000004951.1	ENSTBEP00000004262.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.70e-10	39.0	16	66

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw.....pglknssskefrCPlCr 46
           C+iCl+ f d p+ + CgH f+++C+   w     +   ++ + +f+CP Cr
   Q: 16   CSICLDYFID-PVMTTCGHNFCRECIqLSWekakgKKGRRKRKSSFSCPECR 66
           **********.999************888899999777888**********8 PP

Organism

Tupaia belangeri

Protein Sequence
(Fasta)

MDAVELARKL QEEATCSICL DYFIDPVMTT CGHNFCRECI QLSWEKAKGK KGRRKRKSSF 60
SCPECREMSP QRNLRPNRLL TKVAEMARQH PGLQKRDLCQ VHQEPLKLFC EEDQIPICVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGATGCT GTGGAACTTG CGAGAAAGCT GCAAGAGGAG GCCACATGTT CCATCTGCCT 60
TGATTATTTC ATAGACCCGG TTATGACAAC CTGTGGCCAC AATTTCTGCC GTGAGTGCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0479--Metal-binding
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR010908--Longin_dom
IPR003877--SPRY_dom
IPR032917--TRIM5
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0051607--P:defense response to virus
GO:0045087--P:innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007781	Ashbya gossypii	40.98	1.00e-08	53.90
IUUC-Ame-011061	Astyanax mexicanus	31.17	4.00e-60	225.00
IUUC-Bta-013369	Bos taurus	78.66	0.00e+00	759.00
IUUC-Cja-019509	Callithrix jacchus	77.41	0.00e+00	698.00
IUUC-Cfa-020311	Canis familiaris	78.62	0.00e+00	736.00
IUUC-Cpo-021862	Cavia porcellus	78.41	0.00e+00	700.00
IUUC-Csa-023705	Chlorocebus sabaeus	76.54	1.00e-91	328.00
IUUC-Cho-024594	Choloepus hoffmanni	73.56	8.00e-118	415.00
IUUC-Dre-028792	Danio rerio	31.93	8.00e-59	221.00
IUUC-Dno-029337	Dasypus novemcinctus	80.13	0.00e+00	761.00
IUUC-Dor-030385	Dipodomys ordii	67.06	2.00e-71	262.00
IUUC-Ete-032497	Echinops telfairi	71.91	8.00e-162	562.00
IUUC-Eeu-034725	Erinaceus europaeus	67.88	3.00e-157	547.00
IUUC-Fca-036296	Felis catus	80.29	0.00e+00	752.00
IUUC-Gmo-038505	Gadus morhua	33.05	1.00e-59	223.00
IUUC-Ggo-044516	Gorilla gorilla	81.13	0.00e+00	738.00
IUUC-Hsa-046085	Homo sapiens	81.13	0.00e+00	709.00
IUUC-Itr-048579	Ictidomys tridecemlineatus	83.86	0.00e+00	780.00
IUUC-Loc-052206	Lepisosteus oculatus	32.98	4.00e-64	238.00
IUUC-Mcc-055376	Macaca mulatta	81.76	0.00e+00	712.00
IUUC-Mmr-061341	Microcebus murinus	81.59	0.00e+00	727.00
IUUC-Mmu-064039	Mus musculus	80.92	0.00e+00	773.00
IUUC-Nle-069350	Nomascus leucogenys	80.08	0.00e+00	704.00
IUUC-Opr-071165	Ochotona princeps	74.21	0.00e+00	662.00
IUUC-Ont-071285	Oreochromis niloticus	32.33	5.00e-65	241.00
IUUC-Ola-086677	Oryzias latipes	30.60	2.00e-58	219.00
IUUC-Oga-088905	Otolemur garnettii	81.00	0.00e+00	712.00
IUUC-Ptr-090539	Pan troglodytes	80.08	0.00e+00	695.00
IUUC-Pan-091818	Papio anubis	81.97	0.00e+00	717.00
IUUC-Pfo-097045	Poecilia formosa	31.15	5.00e-60	224.00
IUUC-Pca-101074	Procavia capensis	76.00	5.00e-103	367.00
IUUC-Pva-102309	Pteropus vampyrus	77.81	9.00e-135	472.00
IUUC-Rno-104939	Rattus norvegicus	80.50	0.00e+00	734.00
IUUC-Ssc-115951	Sus scrofa	82.85	0.00e+00	794.00
IUUC-Tru-117532	Takifugu rubripes	29.76	2.00e-56	212.00
IUUC-Tsy-119187	Tarsius syrichta	88.14	9.00e-103	366.00
IUUC-Ttr-129241	Tursiops truncatus	77.52	0.00e+00	719.00
IUUC-Vpa-130125	Vicugna pacos	82.97	4.00e-91	328.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence