iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068050

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AAPE02012057

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000003442.2	ENSMLUT00000003438.2	ENSMLUP00000003128.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	2.60e-60	204.6	2	214

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 21   lvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsvll 109
           +++++g++ ++q+ ++y++dpe l+++++pv+++lllF+i+ek+e +r+++   ++++++++d+ ++++f+kq+i+N+C+t++l+++++
   Q: 2    FLKQLGLHPKWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEE--EEKIKSQGQDVKSSVYFMKQTISNACGTIGLIHAIA 88
           789*********************************************766..5589******************************** PP
   S: 110  ncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglk 197
           n++dk+ ++ G+tl++++e++ ++spe++a+ l+n ++ + ++ s   +++  +  + d      +k  +hf+++v+++g+lyeldg+k
   Q: 89   NNKDKMhFESGSTLKKFLEESVSMSPEERARYLENYDAFKTAQKSNMIKGQVIKAPNID------EKVDLHFIALVHVDGHLYELDGRK 171
           *************************************9999999886666655443433......6789******************** PP
   S: 198  pfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           pfP+++g++++++ l+d+++v+++f+er    + de+rfn++a++a+
   Q: 172  PFPINHGETSDETLLEDAIEVCKKFMER----DPDELRFNAIALSAA 214
           ****************************....***********9875 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

QFLKQLGLHP KWQFVDVYGM DPELLSMVPR PVCAVLLLFP ITEKYEVFRT EEEEKIKSQG 60
QDVKSSVYFM KQTISNACGT IGLIHAIANN KDKMHFESGS TLKKFLEESV SMSPEERARY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTTTCTCA AACAATTAGG CCTGCATCCT AAATGGCAAT TTGTCGATGT ATATGGAATG 60
GATCCTGAAC TCCTTAGCAT GGTACCAAGA CCAGTGTGTG CAGTATTACT TCTCTTCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Mmr-061284	Microcebus murinus	65.22	7.00e-93	333.00
IUUC-Opr-070652	Ochotona princeps	62.00	9.00e-77	279.00
IUUC-Pyt-104587	Pyrenophora triticirepentis	34.91	7.00e-31	127.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence