iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049992

Ensembl Protein ID

ENSLACP00000015736.1

UniProt Accession

H3B1G5; H3B1G5_LATCH

Genbank Protein ID

ENSLACP00000015736

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01093133

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000013859.1	ENSLACT00000015846.1	ENSLACP00000015736.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.20e-189	631.0	440	906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 22   llvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeei 104
           +lvG+g++GcE+lKn++l+Gv      g+it++D d +e+snlnrqFLfr+++++k+K+ +aa+a  e+np+ ++ +   ++++ +e+i
   Q: 440  FLVGCGAIGCEMLKNFALLGVgsdsekGMITITDPDLIEKSNLNRQFLFRPHHIQKPKSFTAAAATLEINPSLRINSQLHKVCPATENI 528
           8**************************************************************************************** PP
   S: 105  v...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa 190
           +   F++k+dvV++aldn+earr+v+++ ++++ pl++sgt+G++G+++vi+++lte+y++++dpp+++iPfctlk++p+++eh i+wa
   Q: 529  YnddFYTKLDVVITALDNVEARRYVDSRSVSNQCPLLDSGTMGTKGHTEVIVPYLTESYNSHRDPPEEEIPFCTLKSFPAVIEHAIQWA 617
           ***************************************************************************************** PP
   S: 191  ............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtk 267
                       +l nk++++++++eevle+++s e++eg ++v  +l s+++  +e +++ia+ +f+k++++++ qll+sf+ d + +
   Q: 618  rdkfessfshkpSLYNKFWQTYPSAEEVLERIKSGESLEGSFQV-IKLLSRRPTYWEHCVQIARIKFEKYFKHKAVQLLHSFPLDTRLN 705
           ********************************************.999***************************************** PP
   S: 268  skspfwv.........................................................sfcsnaealqvpekvekdeevvkas 299
           ++s fw+                                                         +f + +++++++e+v+k+e  +   
   Q: 706  DGSLFWQspkrppspiefdindvlhfsfvvnaaklfantynipyteqdlskdvvfkivskvkipEFRPSEKRVETDESVKKPELSSVNC 794
           **************************************************************************999999987643333 PP
   S: 300  ap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaa 381
           ++      +l++++++ ++ k++++ + +sfekddds  ++d++taa+nlra++++i p +d+ ++k+iag+iipaiat +a+v+Gl+a
   Q: 795  EDervavDQLEKAIASGLSRKENLQLTIISFEKDDDSngHIDFITAASNLRAKMYSIDP-ADRLKTKRIAGKIIPAIATATAAVSGLVA 882
           336789999**************************************************.***************************** PP
   S: 382  qEviKvvsg.kfeplknfflfdae 404
           +E+iKvv g +fe+++n+f+++a+
   Q: 883  LELIKVVGGhPFEAYRNCFFNLAI 906
           *********99*********9876 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

KKQFLISITE DIMEIDDSLY SRQRYVLGDT AMHKMAQSHV FLSGMGGLGV EIAKNIVLAG 60
IKTLTIHDTK QCQTWDLGNN FFIHEDDVRN RKNRTEAILH HIAELNPYVH VKLSTVPLDE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAACAGT TTTTGATCAG CATAACAGAA GACATAATGG AAATTGATGA TTCTTTATAC 60
AGGTAGGAAT TCAACATTTG CTTTCATTTA TTGGAAGCGT TCTTTTTGTG GGGGGGGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	73.56	0.00e+00	1580.00
IUUC-Apl-004158	Anas platyrhynchos	76.18	0.00e+00	1583.00
IUUC-Aca-005349	Anolis carolinensis	74.61	0.00e+00	1597.00
IUUC-Bta-012696	Bos taurus	73.31	0.00e+00	1577.00
IUUC-Cja-019563	Callithrix jacchus	73.18	0.00e+00	1568.00
IUUC-Cfa-020951	Canis familiaris	73.80	0.00e+00	1583.00
IUUC-Cpo-022307	Cavia porcellus	70.28	0.00e+00	1504.00
IUUC-Csa-023647	Chlorocebus sabaeus	73.57	0.00e+00	1581.00
IUUC-Cho-024682	Choloepus hoffmanni	59.01	0.00e+00	711.00
IUUC-Dre-028022	Danio rerio	68.30	0.00e+00	1474.00
IUUC-Dno-029796	Dasypus novemcinctus	73.11	0.00e+00	1548.00
IUUC-Dor-030981	Dipodomys ordii	62.01	0.00e+00	1221.00
IUUC-Ete-032514	Echinops telfairi	62.88	0.00e+00	897.00
IUUC-Eca-033697	Equus caballus	73.31	0.00e+00	1580.00
IUUC-Eeu-035323	Erinaceus europaeus	66.98	0.00e+00	1060.00
IUUC-Fca-035858	Felis catus	73.31	0.00e+00	1581.00
IUUC-Fal-036848	Ficedula albicollis	75.00	0.00e+00	1585.00
IUUC-Gmo-039326	Gadus morhua	67.45	0.00e+00	1375.00
IUUC-Gga-040747	Gallus gallus	75.69	0.00e+00	1579.00
IUUC-Gac-041406	Gasterosteus aculeatus	67.48	0.00e+00	1378.00
IUUC-Ggo-044577	Gorilla gorilla	73.20	0.00e+00	1571.00
IUUC-Hsa-046007	Homo sapiens	73.18	0.00e+00	1563.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	76.55	0.00e+00	858.00
IUUC-Loc-051899	Lepisosteus oculatus	70.45	0.00e+00	1512.00
IUUC-Laf-054413	Loxodonta africana	72.62	0.00e+00	1478.00
IUUC-Mcc-054656	Macaca mulatta	73.47	0.00e+00	1574.00
IUUC-Meu-056463	Macropus eugenii	62.37	0.00e+00	1184.00
IUUC-Mga-059721	Meleagris gallopavo	74.64	0.00e+00	1488.00
IUUC-Mmr-060908	Microcebus murinus	70.44	0.00e+00	1508.00
IUUC-Mdo-062096	Monodelphis domestica	74.63	0.00e+00	1597.00
IUUC-Mmu-064114	Mus musculus	71.82	0.00e+00	1553.00
IUUC-Mpu-066017	Mustela putorius furo	74.39	0.00e+00	1594.00
IUUC-Mlu-068037	Myotis lucifugus	71.97	0.00e+00	1536.00
IUUC-Nle-069494	Nomascus leucogenys	73.08	0.00e+00	1565.00
IUUC-Ont-071592	Oreochromis niloticus	69.25	0.00e+00	1440.00
IUUC-Oan-073268	Ornithorhynchus anatinus	70.38	0.00e+00	1376.00
IUUC-Ocu-074296	Oryctolagus cuniculus	73.39	0.00e+00	1587.00
IUUC-Ola-086376	Oryzias latipes	68.37	0.00e+00	1379.00
IUUC-Oga-088186	Otolemur garnettii	73.03	0.00e+00	1551.00
IUUC-Oar-089307	Ovis aries	73.53	0.00e+00	1588.00
IUUC-Ptr-090609	Pan troglodytes	73.27	0.00e+00	1566.00
IUUC-Pan-092905	Papio anubis	72.97	0.00e+00	1497.00
IUUC-Psi-093489	Pelodiscus sinensis	76.08	0.00e+00	1602.00
IUUC-Pma-094203	Petromyzon marinus	65.73	8.00e-56	208.00
IUUC-Pfo-096670	Poecilia formosa	68.30	0.00e+00	1439.00
IUUC-Pab-098418	Pongo abelii	73.08	0.00e+00	1562.00
IUUC-Pca-100889	Procavia capensis	62.69	0.00e+00	1269.00
IUUC-Pva-103144	Pteropus vampyrus	65.46	0.00e+00	1389.00
IUUC-Rno-105612	Rattus norvegicus	71.53	0.00e+00	1548.00
IUUC-Sha-107388	Sarcophilus harrisii	75.02	0.00e+00	1598.00
IUUC-Sar-113128	Sorex araneus	72.64	0.00e+00	1543.00
IUUC-Ssc-116117	Sus scrofa	73.20	0.00e+00	1566.00
IUUC-Tgu-116565	Taeniopygia guttata	75.20	0.00e+00	1589.00
IUUC-Tru-118591	Takifugu rubripes	68.33	0.00e+00	1411.00
IUUC-Tsy-119436	Tarsius syrichta	64.98	0.00e+00	1326.00
IUUC-Tni-120880	Tetraodon nigroviridis	67.32	0.00e+00	1394.00
IUUC-Tbe-127714	Tupaia belangeri	63.59	0.00e+00	1105.00
IUUC-Ttr-129159	Tursiops truncatus	70.20	0.00e+00	1293.00
IUUC-Vpa-130716	Vicugna pacos	71.24	0.00e+00	1496.00
IUUC-Xtr-132947	Xenopus tropicalis	69.32	0.00e+00	1460.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence