iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062128

UUCD1 version

UUC-MoD-00267

Ensembl Protein ID

ENSMODP00000008768.3

UniProt Accession

F6UEY0; F6UEY0_MONDO

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Gene Name

DCUN1D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000007070.3	ENSMODT00000008941.3	ENSMODP00000008768.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	1.10e-83	280.1	87	278

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkd 90
           s +++eelf+rYkd++e++i++eg+e+fc+dl+vdp++++vLvlawk++aat+c+f+r+ef++g++a+++dsi+++++++++l +e+k+
   Q: 87   SLQRMEELFRRYKDEREEAILEEGMERFCNDLCVDPTEFKVLVLAWKFQAATMCKFTRKEFFEGCKAISADSIDGICARFPSLLNEAKQ 175
           6799************************************************************************************* PP
   S: 91   eqkfkdiYrfafnfakd..kgqksldldtaialwkLllaerefklldawlkfLeee..kkksiskDtWnllLefskviakdlsnYdeeg 175
           e+kfkd+Yrf+f+f++d  +gq+sl++++aialwkL+++++++++ld+wl+fL+e+  + k+is+DtWn++L+f++vi +dlsnY+e++
   Q: 176  EDKFKDLYRFTFQFGLDseEGQRSLHREIAIALWKLVFTQNNPPVLDQWLHFLTENpsGVKGISRDTWNMFLNFTQVIGPDLSNYSEDE 264
           ***************998899**********************************98899***************************** PP
   S: 176  aWPvliDefveylk 189
           aWP+l+D+fve+++
   Q: 265  AWPSLFDTFVEWEM 278
           ************85 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MGQCVTKCKN PSSTLGSKNG DRDPSGKSHS KRSGGHRDDH TPTCGKPGGD ILVNGTKKAE 60
ATSESCQFPT SSGDARRDPE SSTEESSLQR MEELFRRYKD EREEAILEEG MERFCNDLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCCCTTGG TTCTGCTCAG TAGGGTCAGA GTTCCTGCTA GTGCTGCAGA CACCCAGCAT 60
GTGCTGACCT GGTGACAGCC ATAGTTACCA TAATTAGTGA TTAGATATCA CTCAAGAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0005737--C:cytoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0030308--P:negative regulation of cell growth
GO:0043065--P:positive regulation of apoptotic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation
GO:0010332--P:response to gamma radiation
GO:0009314--P:response to radiation
GO:0010225--P:response to UV-C

KEGG

mdo:100026409

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001689	Ailuropoda melanoleuca	87.17	8.00e-155	539.00
IUUC-Apl-003497	Anas platyrhynchos	85.53	1.00e-148	518.00
IUUC-Aca-004961	Anolis carolinensis	82.55	1.00e-148	518.00
IUUC-Aor-009902	Aspergillus oryzae	33.57	9.00e-12	62.40
IUUC-Ame-011413	Astyanax mexicanus	68.59	3.00e-104	371.00
IUUC-Bta-013338	Bos taurus	87.50	2.00e-155	541.00
IUUC-Cja-019458	Callithrix jacchus	86.84	2.00e-154	538.00
IUUC-Cfa-020160	Canis familiaris	87.50	2.00e-155	541.00
IUUC-Cpo-021835	Cavia porcellus	86.84	2.00e-144	504.00
IUUC-Csa-023328	Chlorocebus sabaeus	87.17	5.00e-155	540.00
IUUC-Cho-024888	Choloepus hoffmanni	86.09	1.00e-152	531.00
IUUC-Cin-025134	Ciona intestinalis	53.96	2.00e-61	229.00
IUUC-Csv-025904	Ciona savignyi	52.03	2.00e-33	134.00
IUUC-Dre-027780	Danio rerio	65.11	2.00e-97	348.00
IUUC-Dno-028866	Dasypus novemcinctus	86.84	3.00e-153	534.00
IUUC-Dor-030387	Dipodomys ordii	85.86	3.00e-151	527.00
IUUC-Dme-032081	Drosophila melanogaster	50.00	7.00e-50	191.00
IUUC-Eca-033857	Equus caballus	86.51	2.00e-154	537.00
IUUC-Eeu-034825	Erinaceus europaeus	80.59	4.00e-139	487.00
IUUC-Fca-036130	Felis catus	87.50	1.00e-155	541.00
IUUC-Fal-037296	Ficedula albicollis	84.54	1.00e-145	508.00
IUUC-Gmo-039626	Gadus morhua	64.77	3.00e-97	347.00
IUUC-Ggr-039959	Gaeumannomyces graminis	25.96	9.00e-15	75.50
IUUC-Gga-040741	Gallus gallus	85.20	6.00e-146	509.00
IUUC-Gac-042271	Gasterosteus aculeatus	66.79	8.00e-93	333.00
IUUC-Ggo-044727	Gorilla gorilla	87.17	5.00e-155	540.00
IUUC-Hsa-046288	Homo sapiens	86.84	2.00e-154	538.00
IUUC-Itr-049054	Ictidomys tridecemlineatus	86.51	3.00e-159	554.00
IUUC-Lch-050289	Latimeria chalumnae	79.34	4.00e-133	467.00
IUUC-Loc-052455	Lepisosteus oculatus	71.94	8.00e-108	383.00
IUUC-Laf-054369	Loxodonta africana	85.86	6.00e-147	513.00
IUUC-Mcc-055413	Macaca mulatta	69.81	4.00e-109	387.00
IUUC-Meu-056535	Macropus eugenii	98.03	2.00e-169	587.00
IUUC-Mga-059290	Meleagris gallopavo	84.87	1.00e-146	512.00
IUUC-Mmr-060689	Microcebus murinus	87.17	3.00e-155	540.00
IUUC-Mmu-064396	Mus musculus	86.18	3.00e-159	553.00
IUUC-Mpu-065926	Mustela putorius furo	87.17	8.00e-155	539.00
IUUC-Mlu-067044	Myotis lucifugus	87.17	1.00e-160	558.00
IUUC-Nle-069346	Nomascus leucogenys	87.17	5.00e-155	540.00
IUUC-Opr-070682	Ochotona princeps	86.51	9.00e-143	499.00
IUUC-Ont-071772	Oreochromis niloticus	69.18	6.00e-102	363.00
IUUC-Oan-072765	Ornithorhynchus anatinus	85.86	5.00e-149	520.00
IUUC-Ocu-074272	Oryctolagus cuniculus	90.74	3.00e-111	394.00
IUUC-Ola-087561	Oryzias latipes	66.67	1.00e-104	372.00
IUUC-Oga-088440	Otolemur garnettii	72.63	2.00e-115	408.00
IUUC-Oar-089403	Ovis aries	87.17	2.00e-155	541.00
IUUC-Ptr-091384	Pan troglodytes	87.17	5.00e-155	540.00
IUUC-Pan-092650	Papio anubis	87.17	5.00e-155	540.00
IUUC-Psi-093806	Pelodiscus sinensis	85.20	5.00e-139	486.00
IUUC-Pma-094196	Petromyzon marinus	50.47	2.00e-85	308.00
IUUC-Pfo-096584	Poecilia formosa	70.00	8.00e-106	376.00
IUUC-Pab-098605	Pongo abelii	87.17	5.00e-155	540.00
IUUC-Pca-100933	Procavia capensis	71.05	3.00e-107	380.00
IUUC-Pva-102172	Pteropus vampyrus	83.39	2.00e-151	528.00
IUUC-Rno-105406	Rattus norvegicus	86.18	3.00e-159	553.00
IUUC-Sha-106531	Sarcophilus harrisii	98.36	8.00e-171	592.00
IUUC-Sar-113051	Sorex araneus	70.72	4.00e-109	387.00
IUUC-Ssc-115555	Sus scrofa	86.84	6.00e-155	539.00
IUUC-Tgu-117178	Taeniopygia guttata	85.20	8.00e-148	516.00
IUUC-Tru-117876	Takifugu rubripes	67.83	5.00e-105	373.00
IUUC-Tsy-118790	Tarsius syrichta	87.34	2.00e-126	444.00
IUUC-Tni-119673	Tetraodon nigroviridis	68.99	2.00e-106	379.00
IUUC-Tbe-127429	Tupaia belangeri	87.50	9.00e-156	542.00
IUUC-Ttr-128467	Tursiops truncatus	87.17	2.00e-155	541.00
IUUC-Vpa-130376	Vicugna pacos	62.18	1.00e-90	325.00
IUUC-Xtr-132134	Xenopus tropicalis	76.07	2.00e-123	435.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence