iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071966

Ensembl Protein ID

ENSONIP00000025418.1

UniProt Accession

I3KWC2; I3KWC2_ORENI

Genbank Protein ID

ENSONIP00000025418

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01030279

Gene Name

si:dkey-1f12.3; eml5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000020175.1	ENSONIT00000025439.1	ENSONIP00000025418.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-56	185.0	105	143
UBD/Beta-Prp	9.50e-126	419.4	723	939

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvll 36
           Ht ++ claf  +   lvs + D  +ti vWD+r+g++l
   Q: 105  HTHGIACLAFdLEgQCLVSVGLDskNTICVWDWRRGKVL 143
           99********8445779****9999**********9976 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrslsg.heaevtavkfspdgk..ilvtgseD..rtikvwdlstgkc 86
           ++gh+++ ++ ++ +p k+++atg  +rd++i +wd+++ k ++ l+g h+ +v a++fs +++   l++++ D  +ti +wd ++g+ 
   Q: 723  YMGHDDDILC-LALHPLKDFVATGqvGRDSSIHIWDTEMLKPMSVLKGfHQLGVCALDFSATADgkRLASVGLDdnHTIVLWDWRKGEK 810
           5778887777.9999********96669******************665***********988777******99999************ PP
   S: 87   vhtlkghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllr 173
           +++++g +d++  ++++p+  dkl++++ ++  + w+   g  +    + g++++ +c+v+  ++ +++sG+  + + +W  + ++l++
   Q: 811  LSAMRGSKDKIFVVKINPYLpDKLITAG-VKHMKFWHKAGGGLIGRkGNMGKTETMMCAVYGWSEEMVFSGTCTGDICIW--RDMFLMK 896
           ******************9978888887.99*****8888887766799*******************************..88***** PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
           t +  h+++v s+   +  k +v+g++dg v lwd   ++c++t+ 
   Q: 897  TVKA-HDGPVFSMHALE--KGFVTGGKDGIVALWDDTFERCLKTYA 939
           **98.********9888..67*********************9996 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MADRTAPNCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYNTR EHKQKFYLGH 60
NDDIISLALH PERVLVATGQ VGKEPYICVW DSYTVQTVSI LKDVHTHGIA CLAFDLEGQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCTTGTGGA ATAACAGTAC AGCTCCATCT TTGTAGGATT TGACAGGAGC TTTGACCCGA 60
CTCGAAGAGG ACCGCGAGCC CGGGGCTGAA GTACAAGTAG ACTAAATGAA AACACAAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR003143--Cyt_cd1_C
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	84.83	0.00e+00	3446.00
IUUC-Apl-003360	Anas platyrhynchos	86.76	0.00e+00	3425.00
IUUC-Ame-011681	Astyanax mexicanus	93.71	0.00e+00	3780.00
IUUC-Bta-012838	Bos taurus	84.01	0.00e+00	3457.00
IUUC-Cja-019068	Callithrix jacchus	84.40	0.00e+00	3467.00
IUUC-Cfa-020531	Canis familiaris	85.10	0.00e+00	3511.00
IUUC-Cpo-022304	Cavia porcellus	82.23	0.00e+00	3270.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	33.33	7.00e-99	357.00
IUUC-Csa-023621	Chlorocebus sabaeus	83.84	0.00e+00	3162.00
IUUC-Cho-024944	Choloepus hoffmanni	66.76	0.00e+00	1325.00
IUUC-Dre-028772	Danio rerio	93.11	0.00e+00	3759.00
IUUC-Dno-030063	Dasypus novemcinctus	83.79	0.00e+00	3440.00
IUUC-Dor-030980	Dipodomys ordii	77.06	0.00e+00	1454.00
IUUC-Ete-032554	Echinops telfairi	83.42	0.00e+00	959.00
IUUC-Eca-033909	Equus caballus	84.35	0.00e+00	3193.00
IUUC-Eeu-035180	Erinaceus europaeus	70.44	0.00e+00	1317.00
IUUC-Fal-037219	Ficedula albicollis	87.10	0.00e+00	3545.00
IUUC-Gmo-039146	Gadus morhua	90.54	0.00e+00	3638.00
IUUC-Gga-041095	Gallus gallus	86.94	0.00e+00	2568.00
IUUC-Gac-041341	Gasterosteus aculeatus	95.12	0.00e+00	3786.00
IUUC-Hsa-045997	Homo sapiens	84.30	0.00e+00	3462.00
IUUC-Lch-050306	Latimeria chalumnae	84.77	0.00e+00	3178.00
IUUC-Loc-052215	Lepisosteus oculatus	91.71	0.00e+00	3761.00
IUUC-Laf-054044	Loxodonta africana	83.37	0.00e+00	3437.00
IUUC-Mcc-054733	Macaca mulatta	84.20	0.00e+00	3459.00
IUUC-Meu-055977	Macropus eugenii	74.78	0.00e+00	1835.00
IUUC-Mga-059666	Meleagris gallopavo	85.38	0.00e+00	3354.00
IUUC-Mmr-060995	Microcebus murinus	84.69	0.00e+00	3459.00
IUUC-Mdo-062482	Monodelphis domestica	85.69	0.00e+00	3519.00
IUUC-Mmu-063533	Mus musculus	84.30	0.00e+00	3425.00
IUUC-Mpu-066704	Mustela putorius furo	84.86	0.00e+00	3484.00
IUUC-Mlu-067592	Myotis lucifugus	83.80	0.00e+00	3427.00
IUUC-Nle-069911	Nomascus leucogenys	84.54	0.00e+00	3465.00
IUUC-Ola-086738	Oryzias latipes	95.22	0.00e+00	3835.00
IUUC-Oga-088436	Otolemur garnettii	82.74	0.00e+00	3407.00
IUUC-Oar-090153	Ovis aries	84.74	0.00e+00	3353.00
IUUC-Ptr-091008	Pan troglodytes	84.01	0.00e+00	3440.00
IUUC-Pan-092404	Papio anubis	84.90	0.00e+00	3464.00
IUUC-Psi-093417	Pelodiscus sinensis	85.77	0.00e+00	3393.00
IUUC-Pfo-096073	Poecilia formosa	96.75	0.00e+00	3914.00
IUUC-Pab-097900	Pongo abelii	83.90	0.00e+00	3444.00
IUUC-Pca-100107	Procavia capensis	70.45	0.00e+00	2251.00
IUUC-Pva-102880	Pteropus vampyrus	81.56	0.00e+00	3186.00
IUUC-Rno-106084	Rattus norvegicus	84.30	0.00e+00	3477.00
IUUC-Sha-106974	Sarcophilus harrisii	85.48	0.00e+00	3502.00
IUUC-Sar-113401	Sorex araneus	76.16	0.00e+00	1654.00
IUUC-Ssc-116057	Sus scrofa	84.00	0.00e+00	3398.00
IUUC-Tru-118444	Takifugu rubripes	95.68	0.00e+00	3820.00
IUUC-Tsy-118941	Tarsius syrichta	74.45	0.00e+00	2538.00
IUUC-Tni-120683	Tetraodon nigroviridis	95.33	0.00e+00	3665.00
IUUC-Tbe-127467	Tupaia belangeri	77.78	0.00e+00	1646.00
IUUC-Ttr-129138	Tursiops truncatus	81.34	0.00e+00	3178.00
IUUC-Vpa-130083	Vicugna pacos	79.40	0.00e+00	3083.00
IUUC-Xtr-131835	Xenopus tropicalis	85.59	0.00e+00	3531.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence