iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Olu-087665

Ensembl Protein ID

ABO96298

UniProt Accession

A4RXI6; A4RXI6_OSTLU

Genbank Protein ID

ABO96298.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

CP000585

Gene Name

OSTLU_12545

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OSTLU_12545	ABO96298	ABO96298

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.20e-64	217.4	2	294

Active Site

Position(s)	Description	Evidence
83	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
158	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsv 107
           +w+ +esdPg+f +lv++ g +++  + elysLd + l+   ep++gl++lFk+   + ss            vde+  + +ffa qvi N+Cat+A+lsv
   Q: 2    DWCLIESDPGVFGELVHRIGARGV-AFTELYSLDVDELRRN-EPIYGLIFLFKWRGGHSSSA---------VEVDENPPQDLFFASQVIHNACATQAVLSV 91
           7***********************.************9998.**************999998.........4589************************** PP
   S: 108  llncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPldlgkkke 208
           lln e++ ++lG+tl+ l+e+t  +++e k+  ++n++ ++ +hns+ar+e+  +++r     +q ++++fhfv+yv+ +g ++eldgl+  P+++g+ ++
   Q: 92   LLNAEQE-VELGETLQTLREFTLDFDAETKGMSISNSDIIRDAHNSFARPEPIVLQSRP----AQEDDDVFHFVAYVPRGGSVFELDGLQRGPINHGSFGD 187
           ******9.6********************************************999998....5558*******************************887 PP
   S: 209  teelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkidkeLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifi 309
              + d +   +    +i    s+ei+fnl+a+ +d r+++ +rl      +eL +  +    e+++ + +l+ e+ k  ++  d+irR++ny   ++ ++
   Q: 188  GH-WLDVAVPAI--QRKIASFASNEIKFNLMAVTKDPRIAISQRL------EELRSSSTGAADEIAHLQRELEVEEAKVAEWRNDNIRRRHNYIPLVFALL 279
           65.555555555..59*****************************......8999999******************************************* PP
   S: 310  kdlaregilrklvee 324
           k  a  + l +  e+
   Q: 280  KEVAAAKKLTEALEQ 294
           **9999988888777 PP

Organism

Ostreococcus lucimarinus

Protein Sequence
(Fasta)

MDWCLIESDP GVFGELVHRI GARGVAFTEL YSLDVDELRR NEPIYGLIFL FKWRGGHSSS 60
AVEVDENPPQ DLFFASQVIH NACATQAVLS VLLNAEQEVE LGETLQTLRE FTLDFDAETK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACTGGT GCCTCATCGA GAGCGATCCC GGGGTCTTCG GCGAGCTGGT CCATCGAATC 60
GGCGCGCGTG GCGTCGCATT CACAGAACTC TACTCGCTAG ACGTTGATGA ACTTCGTCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

olu:OSTLU_12545

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	45.12	3.00e-79	286.00
IUUC-Aml-001866	Ailuropoda melanoleuca	41.25	2.00e-72	263.00
IUUC-Atr-002966	Amborella trichopoda	41.84	6.00e-68	248.00
IUUC-Apl-003306	Anas platyrhynchos	37.94	8.00e-67	244.00
IUUC-Aca-004763	Anolis carolinensis	41.25	2.00e-72	263.00
IUUC-Aly-005581	Arabidopsis lyrata	43.54	8.00e-70	254.00
IUUC-Ath-007283	Arabidopsis thaliana	44.08	1.00e-72	263.00
IUUC-Ago-007999	Ashbya gossypii	33.11	5.00e-33	132.00
IUUC-Acl-008231	Aspergillus clavatus	38.32	5.00e-54	202.00
IUUC-Afl-008557	Aspergillus flavus	39.02	2.00e-54	203.00
IUUC-Afu-008988	Aspergillus fumigatus	37.46	3.00e-52	196.00
IUUC-Ani-009420	Aspergillus nidulans	40.13	2.00e-56	209.00
IUUC-Ang-009859	Aspergillus niger	35.49	3.00e-48	183.00
IUUC-Aor-010145	Aspergillus oryzae	39.02	2.00e-54	203.00
IUUC-Ate-010347	Aspergillus terreus	35.45	2.00e-51	193.00
IUUC-Ame-010791	Astyanax mexicanus	39.62	1.00e-73	267.00
IUUC-Bgr-012298	Blumeria graminis	39.46	2.00e-51	193.00
IUUC-Bta-013251	Bos taurus	41.72	7.00e-73	264.00
IUUC-Bci-013786	Botrytis cinerea	41.40	1.00e-61	227.00
IUUC-Bdi-014132	Brachypodium distachyon	45.68	2.00e-73	266.00
IUUC-Bol-015611	Brassica oleracea	45.85	3.00e-74	269.00
IUUC-Bra-017769	Brassica rapa	45.85	6.00e-74	268.00
IUUC-Cel-018604	Caenorhabditis elegans	40.13	4.00e-64	235.00
IUUC-Cja-019768	Callithrix jacchus	37.46	8.00e-67	244.00
IUUC-Cfa-020207	Canis familiaris	41.25	2.00e-72	263.00
IUUC-Cpo-021925	Cavia porcellus	41.12	1.00e-69	253.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	43.93	2.00e-68	249.00
IUUC-Csa-023958	Chlorocebus sabaeus	41.72	1.00e-72	264.00
IUUC-Cho-024928	Choloepus hoffmanni	53.95	9.00e-19	85.10
IUUC-Cin-025771	Ciona intestinalis	38.18	1.00e-64	237.00
IUUC-Csv-026149	Ciona savignyi	40.32	1.00e-65	240.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	38.81	3.00e-53	199.00
IUUC-Cne-026955	Cryptococcus neoformans	37.11	6.00e-53	198.00
IUUC-Cme-027104	Cyanidioschyzon merolae	37.43	1.00e-51	194.00
IUUC-Dre-027409	Danio rerio	39.31	4.00e-72	262.00
IUUC-Dno-028921	Dasypus novemcinctus	41.25	8.00e-72	261.00
IUUC-Dor-030891	Dipodomys ordii	42.16	6.00e-31	126.00
IUUC-Dse-031170	Dothistroma septosporum	41.20	5.00e-56	208.00
IUUC-Dme-031677	Drosophila melanogaster	43.18	1.00e-72	264.00
IUUC-Ete-032646	Echinops telfairi	39.74	1.00e-36	145.00
IUUC-Eca-033776	Equus caballus	39.79	2.00e-63	233.00
IUUC-Eeu-035305	Erinaceus europaeus	41.99	1.00e-38	150.00
IUUC-Fca-035846	Felis catus	37.88	7.00e-68	248.00
IUUC-Fal-037597	Ficedula albicollis	39.08	6.00e-63	231.00
IUUC-Fox-037670	Fusarium oxysporum	40.21	5.00e-52	195.00
IUUC-Fso-038243	Fusarium solani	39.12	3.00e-52	196.00
IUUC-Gmo-038499	Gadus morhua	38.28	6.00e-65	238.00
IUUC-Ggr-039975	Gaeumannomyces graminis	37.58	4.00e-50	189.00
IUUC-Gga-040904	Gallus gallus	41.82	3.00e-76	276.00
IUUC-Gac-042058	Gasterosteus aculeatus	39.93	2.00e-70	256.00
IUUC-Gma-043030	Glycine max	43.75	7.00e-74	268.00
IUUC-Ggo-044699	Gorilla gorilla	39.53	3.00e-65	239.00
IUUC-Hsa-046227	Homo sapiens	41.58	6.00e-73	265.00
IUUC-Hvu-047359	Hordeum vulgare	45.12	2.00e-78	283.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	37.72	2.00e-67	247.00
IUUC-Lch-049829	Latimeria chalumnae	41.58	2.00e-72	263.00
IUUC-Lpe-050899	Leersia perrieri	46.08	3.00e-71	259.00
IUUC-Loc-052264	Lepisosteus oculatus	39.80	9.00e-70	254.00
IUUC-Lma-053110	Leptosphaeria maculans	42.21	1.00e-54	204.00
IUUC-Laf-053639	Loxodonta africana	41.25	2.00e-72	263.00
IUUC-Mcc-055506	Macaca mulatta	41.72	1.00e-72	264.00
IUUC-Meu-056267	Macropus eugenii	40.96	1.00e-41	162.00
IUUC-Mor-057001	Magnaporthe oryzae	39.18	2.00e-51	193.00
IUUC-Mpo-057608	Magnaporthe poae	43.09	6.00e-34	134.00
IUUC-Mtr-057731	Medicago truncatula	44.21	3.00e-77	279.00
IUUC-Mla-059016	Melampsora laricipopulina	39.39	6.00e-41	157.00
IUUC-Mga-060178	Meleagris gallopavo	40.47	2.00e-67	246.00
IUUC-Mvi-060353	Microbotryum violaceum	38.96	2.00e-55	206.00
IUUC-Mmr-060738	Microcebus murinus	41.58	8.00e-73	264.00
IUUC-Mdo-062266	Monodelphis domestica	46.53	8.00e-56	207.00
IUUC-Mmu-063619	Mus musculus	41.25	2.00e-72	263.00
IUUC-Mac-065301	Musa acuminata	48.06	7.00e-81	291.00
IUUC-Mpu-066058	Mustela putorius furo	41.25	2.00e-72	263.00
IUUC-Mlu-067292	Myotis lucifugus	41.72	1.00e-72	263.00
IUUC-Nfi-068275	Neosartorya fischeri	39.13	9.00e-55	204.00
IUUC-Ncr-068713	Neurospora crassa	40.99	7.00e-60	221.00
IUUC-Nle-069013	Nomascus leucogenys	41.72	6.00e-72	262.00
IUUC-Opr-070628	Ochotona princeps	35.67	8.00e-60	221.00
IUUC-Ont-072688	Oreochromis niloticus	40.33	2.00e-69	253.00
IUUC-Oan-073004	Ornithorhynchus anatinus	43.06	4.00e-55	205.00
IUUC-Ocu-074303	Oryctolagus cuniculus	41.25	2.00e-71	260.00
IUUC-Oba-075002	Oryza barthii	45.06	1.00e-74	270.00
IUUC-Obr-076392	Oryza brachyantha	45.14	3.00e-73	266.00
IUUC-Ogl-077271	Oryza glaberrima	45.06	1.00e-74	270.00
IUUC-Ogu-078493	Oryza glumaepatula	45.06	2.00e-74	270.00
IUUC-Oin-080084	Oryza indica	45.06	2.00e-74	270.00
IUUC-Olo-080803	Oryza longistaminata	44.75	5.00e-74	268.00
IUUC-Ome-081146	Oryza meridionalis	44.44	1.00e-73	267.00
IUUC-Oni-082146	Oryza nivara	45.06	2.00e-74	270.00
IUUC-Opu-083633	Oryza punctata	44.83	2.00e-72	263.00
IUUC-Oru-084789	Oryza rufipogon	45.06	2.00e-74	270.00
IUUC-Osa-086196	Oryza sativa	45.06	2.00e-74	270.00
IUUC-Ola-087126	Oryzias latipes	39.93	8.00e-71	258.00
IUUC-Oga-089140	Otolemur garnettii	38.18	1.00e-68	250.00
IUUC-Oar-090296	Ovis aries	41.53	2.00e-71	259.00
IUUC-Ptr-090566	Pan troglodytes	41.58	6.00e-73	265.00
IUUC-Pan-092052	Papio anubis	41.72	1.00e-72	264.00
IUUC-Psi-093723	Pelodiscus sinensis	39.44	2.00e-63	233.00
IUUC-Pma-094568	Petromyzon marinus	44.95	9.00e-54	201.00
IUUC-Pno-095120	Phaeosphaeria nodorum	39.30	9.00e-56	207.00
IUUC-Ppa-095761	Physcomitrella patens	42.61	1.00e-71	260.00
IUUC-Pfo-096210	Poecilia formosa	39.93	1.00e-70	257.00
IUUC-Pab-098463	Pongo abelii	41.58	2.00e-72	263.00
IUUC-Pop-099109	Populus trichocarpa	42.43	9.00e-73	264.00
IUUC-Pca-100108	Procavia capensis	44.68	1.00e-61	227.00
IUUC-Ppe-101176	Prunus persica	43.98	2.00e-74	269.00
IUUC-Pva-102629	Pteropus vampyrus	45.49	9.00e-63	231.00
IUUC-Pgr-103419	Puccinia graminis	38.82	4.00e-52	195.00
IUUC-Pte-104207	Pyrenophora teres	48.17	7.00e-37	144.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	41.78	5.00e-60	222.00
IUUC-Rno-105579	Rattus norvegicus	35.53	4.00e-60	222.00
IUUC-Sha-106894	Sarcophilus harrisii	41.22	1.00e-59	220.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	41.64	3.00e-62	229.00
IUUC-Spo-108371	Schizosaccharomyces pombe	41.23	2.00e-63	233.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	39.77	6.00e-51	191.00
IUUC-Smo-109396	Selaginella moellendorffii	44.95	4.00e-75	272.00
IUUC-Sit-110630	Setaria italica	45.71	5.00e-74	268.00
IUUC-Sly-110972	Solanum lycopersicum	43.45	1.00e-69	254.00
IUUC-Stu-112185	Solanum tuberosum	45.18	1.00e-79	287.00
IUUC-Sar-113294	Sorex araneus	36.12	2.00e-61	227.00
IUUC-Sbi-113951	Sorghum bicolor	46.01	8.00e-75	271.00
IUUC-Ssc-115501	Sus scrofa	39.59	1.00e-65	240.00
IUUC-Tgu-117152	Taeniopygia guttata	39.08	6.00e-63	231.00
IUUC-Tru-118388	Takifugu rubripes	39.93	4.00e-70	255.00
IUUC-Tsy-119109	Tarsius syrichta	41.58	1.00e-72	264.00
IUUC-Tni-120048	Tetraodon nigroviridis	39.93	3.00e-70	256.00
IUUC-Tca-121750	Theobroma cacao	42.73	8.00e-79	284.00
IUUC-Tre-122130	Trichoderma reesei	40.50	4.00e-53	199.00
IUUC-Tvi-122284	Trichoderma virens	40.07	4.00e-52	196.00
IUUC-Tae-124082	Triticum aestivum	44.82	1.00e-78	284.00
IUUC-Tur-126366	Triticum urartu	37.93	3.00e-53	200.00
IUUC-Tme-127187	Tuber melanosporum	40.07	1.00e-61	227.00
IUUC-Tbe-127619	Tupaia belangeri	35.34	4.00e-46	175.00
IUUC-Ttr-128867	Tursiops truncatus	38.33	1.00e-49	187.00
IUUC-Vda-129912	Verticillium dahliae	39.93	8.00e-54	201.00
IUUC-Vpa-130552	Vicugna pacos	47.03	3.00e-56	209.00
IUUC-Vvi-130881	Vitis vinifera	44.28	2.00e-75	273.00
IUUC-Xtr-131934	Xenopus tropicalis	40.89	6.00e-74	268.00
IUUC-Xma-133312	Xiphophorus maculatus	39.93	1.00e-70	257.00
IUUC-Yli-134487	Yarrowia lipolytica	36.77	3.00e-55	206.00
IUUC-Zma-135462	Zea mays	38.96	4.00e-60	222.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence