iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133312

Ensembl Protein ID

ENSXMAP00000002704.1

UniProt Accession

M3ZKG2; M3ZKG2_XIPMA

Genbank Protein ID

ENSXMAP00000002704

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AGAJ01010182

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000002691.1	ENSXMAT00000002709.1	ENSXMAP00000002704.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.90e-94	316.9	1	316

Active Site

Position(s)	Description	Evidence
88	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
164	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 1    mnsqvkewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktif 89
           m++ + ew+ +esdPg+ft+l++ fg+k+  qvee++s++pen++ + +pv+gl++lFk+++ +e +          ++v+++ ++ if
   Q: 1    MSGSAGEWCLMESDPGVFTELIKGFGCKGA-QVEEIWSMEPENFENL-KPVHGLIFLFKWQPGEEPAG---------SIVQDSRLDHIF 78
           678889************************.****************.*******************9.........8899******** PP
   S: 90   fakqvigNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeaf 178
           fakqvi+N+Cat+A++svllnc++  + lG+tl +++e++++++  +k+lal+n++v++++hns+ar+++++ + + +++    +++af
   Q: 79   FAKQVINNACATQAIISVLLNCSHPDMLLGDTLTEFREFSQSFDGAMKGLALSNSEVIRQVHNSFARQQMFEFDAKSSAK----DEDAF 163
           **************************************************************************998777....79*** PP
   S: 179  hfvsyvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid........ 259
           hfvsyv++ngrlyeldgl++ P+dlg  ++++++ ++++ v+   +ri++++++eirfnl+aiv+dr++++++++  l+ +        
   Q: 164  HFVSYVPVNGRLYELDGLREGPIDLGT-CNQDDWISAVRPVI--EKRIQKYSEGEIRFNLMAIVSDRKMVYEKKIAELQAQlteeepmd 249
           **************************9.78999*********..******************************988877788888888 PP
   S: 260  .keLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveet 325
             +   +l+ i+se++k +  +++e++k k++ki++irR++ny  fi++++k+la+ ++l  lve+ 
   Q: 250  tDQNNTFLSSIQSEIAKCQLLIEEENQKLKRYKIENIRRKHNYLPFIMELLKTLAEYQQLIPLVEKA 316
           8344589*********************************************************984 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MSGSAGEWCL MESDPGVFTE LIKGFGCKGA QVEEIWSMEP ENFENLKPVH GLIFLFKWQP 60
GEEPAGSIVQ DSRLDHIFFA KQVINNACAT QAIISVLLNC SHPDMLLGDT LTEFREFSQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGCGTACC CAGCGCTCAC ATTGCACCGC ATAGAAGTGA GGTCACTGTG CTACAATTAA 60
TTAGCCTAGC TAGCGTGTGC ACCGCTAAGC TATAATAATT TGATAAATAT ATATGTTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37
IPR033837--UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0031011--C:Ino80 complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

xma:102219308

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	46.55	2.00e-83	302.00
IUUC-Aml-001866	Ailuropoda melanoleuca	89.46	6.00e-172	596.00
IUUC-Atr-002966	Amborella trichopoda	46.55	4.00e-81	295.00
IUUC-Apl-003306	Anas platyrhynchos	81.01	7.00e-168	583.00
IUUC-Aca-004763	Anolis carolinensis	90.71	2.00e-173	601.00
IUUC-Aly-005581	Arabidopsis lyrata	48.01	5.00e-80	291.00
IUUC-Ath-007283	Arabidopsis thaliana	47.71	4.00e-82	297.00
IUUC-Ago-007999	Ashbya gossypii	33.12	8.00e-32	130.00
IUUC-Acl-008231	Aspergillus clavatus	43.75	5.00e-53	201.00
IUUC-Afl-008557	Aspergillus flavus	38.03	5.00e-55	207.00
IUUC-Afu-008988	Aspergillus fumigatus	44.77	7.00e-54	204.00
IUUC-Ani-009420	Aspergillus nidulans	37.31	9.00e-54	203.00
IUUC-Ang-009859	Aspergillus niger	41.11	3.00e-49	188.00
IUUC-Aor-010145	Aspergillus oryzae	38.03	5.00e-55	207.00
IUUC-Ate-010347	Aspergillus terreus	42.29	7.00e-53	201.00
IUUC-Ame-010791	Astyanax mexicanus	93.01	0.00e+00	640.00
IUUC-Bgr-012298	Blumeria graminis	37.70	6.00e-50	191.00
IUUC-Bta-013251	Bos taurus	88.50	6.00e-169	586.00
IUUC-Bci-013786	Botrytis cinerea	37.17	3.00e-56	211.00
IUUC-Bdi-014132	Brachypodium distachyon	49.07	2.00e-81	295.00
IUUC-Bol-015611	Brassica oleracea	48.77	3.00e-83	301.00
IUUC-Bra-017769	Brassica rapa	48.77	5.00e-83	301.00
IUUC-Cel-018604	Caenorhabditis elegans	47.35	1.00e-81	296.00
IUUC-Cja-019768	Callithrix jacchus	81.23	4.00e-165	573.00
IUUC-Cfa-020207	Canis familiaris	89.46	6.00e-172	596.00
IUUC-Cpo-021925	Cavia porcellus	85.30	1.00e-162	565.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	44.31	5.00e-74	271.00
IUUC-Csa-023958	Chlorocebus sabaeus	88.82	3.00e-169	587.00
IUUC-Cho-024928	Choloepus hoffmanni	85.71	4.00e-37	148.00
IUUC-Cin-025771	Ciona intestinalis	55.28	7.00e-102	363.00
IUUC-Csv-026149	Ciona savignyi	57.68	8.00e-105	373.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	37.87	2.00e-51	196.00
IUUC-Cne-026955	Cryptococcus neoformans	35.99	1.00e-51	196.00
IUUC-Cme-027104	Cyanidioschyzon merolae	33.15	1.00e-49	190.00
IUUC-Dre-027409	Danio rerio	93.92	0.00e+00	645.00
IUUC-Dno-028921	Dasypus novemcinctus	89.14	3.00e-171	593.00
IUUC-Dse-031170	Dothistroma septosporum	37.66	3.00e-55	208.00
IUUC-Dme-031677	Drosophila melanogaster	58.79	4.00e-113	400.00
IUUC-Ete-032707	Echinops telfairi	62.07	1.00e-107	382.00
IUUC-Eca-033776	Equus caballus	89.58	1.00e-156	545.00
IUUC-Eeu-035305	Erinaceus europaeus	70.74	9.00e-76	276.00
IUUC-Fca-035846	Felis catus	82.35	2.00e-166	578.00
IUUC-Fal-037597	Ficedula albicollis	89.58	2.00e-151	528.00
IUUC-Fox-037670	Fusarium oxysporum	48.05	1.00e-52	200.00
IUUC-Fso-038243	Fusarium solani	48.48	7.00e-53	200.00
IUUC-Gmo-038499	Gadus morhua	89.46	1.00e-169	588.00
IUUC-Ggr-039975	Gaeumannomyces graminis	41.70	4.00e-47	181.00
IUUC-Gga-040904	Gallus gallus	89.43	8.00e-180	622.00
IUUC-Gac-042058	Gasterosteus aculeatus	94.89	0.00e+00	625.00
IUUC-Gma-043763	Glycine max	49.26	6.00e-86	310.00
IUUC-Ggo-044699	Gorilla gorilla	83.06	3.00e-154	537.00
IUUC-Hsa-046227	Homo sapiens	89.14	1.00e-171	595.00
IUUC-Hvu-047359	Hordeum vulgare	48.01	6.00e-82	297.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	80.81	4.00e-165	573.00
IUUC-Lch-049829	Latimeria chalumnae	90.10	2.00e-171	595.00
IUUC-Lpe-050899	Leersia perrieri	48.26	2.00e-78	285.00
IUUC-Loc-052264	Lepisosteus oculatus	93.31	6.00e-175	606.00
IUUC-Lma-053110	Leptosphaeria maculans	37.91	7.00e-47	181.00
IUUC-Laf-053639	Loxodonta africana	89.46	6.00e-172	596.00
IUUC-Mcc-055506	Macaca mulatta	88.82	3.00e-169	587.00
IUUC-Mor-057001	Magnaporthe oryzae	44.73	1.00e-52	199.00
IUUC-Mpo-057608	Magnaporthe poae	41.62	4.00e-32	130.00
IUUC-Mtr-057731	Medicago truncatula	49.85	3.00e-86	311.00
IUUC-Mla-059016	Melampsora laricipopulina	42.29	7.00e-42	163.00
IUUC-Mga-060178	Meleagris gallopavo	89.80	6.00e-166	576.00
IUUC-Mvi-060353	Microbotryum violaceum	39.10	4.00e-54	204.00
IUUC-Mmr-060738	Microcebus murinus	89.46	4.00e-172	597.00
IUUC-Mdo-062266	Monodelphis domestica	90.20	6.00e-113	399.00
IUUC-Mmu-063619	Mus musculus	87.54	1.00e-168	585.00
IUUC-Mac-065301	Musa acuminata	50.79	1.00e-88	319.00
IUUC-Mpu-066058	Mustela putorius furo	89.14	3.00e-171	594.00
IUUC-Mlu-067292	Myotis lucifugus	87.86	1.00e-167	581.00
IUUC-Nfi-068275	Neosartorya fischeri	38.26	2.00e-55	209.00
IUUC-Ncr-068713	Neurospora crassa	38.80	5.00e-58	218.00
IUUC-Nle-069013	Nomascus leucogenys	88.50	9.00e-169	586.00
IUUC-Opr-070628	Ochotona princeps	77.94	9.00e-155	539.00
IUUC-Ont-072688	Oreochromis niloticus	96.51	0.00e+00	632.00
IUUC-Oan-073004	Ornithorhynchus anatinus	87.80	4.00e-131	460.00
IUUC-Ocu-074303	Oryctolagus cuniculus	89.14	3.00e-171	595.00
IUUC-Oba-075002	Oryza barthii	48.80	3.00e-82	298.00
IUUC-Obr-076392	Oryza brachyantha	48.90	2.00e-79	289.00
IUUC-Ogl-077271	Oryza glaberrima	48.80	3.00e-82	298.00
IUUC-Ogu-078493	Oryza glumaepatula	48.80	4.00e-83	301.00
IUUC-Oin-080084	Oryza indica	48.80	4.00e-83	301.00
IUUC-Olo-080803	Oryza longistaminata	48.49	1.00e-82	299.00
IUUC-Ome-081146	Oryza meridionalis	47.89	2.00e-81	296.00
IUUC-Oni-082146	Oryza nivara	48.80	4.00e-83	301.00
IUUC-Opu-083633	Oryza punctata	48.90	3.00e-78	285.00
IUUC-Oru-084789	Oryza rufipogon	48.80	4.00e-83	301.00
IUUC-Osa-086196	Oryza sativa	48.80	4.00e-83	301.00
IUUC-Ola-087126	Oryzias latipes	94.89	8.00e-176	608.00
IUUC-Olu-087665	Ostreococcus lucimarinus	40.28	3.00e-67	248.00
IUUC-Oga-089140	Otolemur garnettii	81.76	2.00e-166	578.00
IUUC-Oar-090296	Ovis aries	88.18	2.00e-169	588.00
IUUC-Ptr-090566	Pan troglodytes	89.14	1.00e-171	595.00
IUUC-Pan-092052	Papio anubis	88.82	4.00e-169	587.00
IUUC-Psi-093723	Pelodiscus sinensis	90.28	5.00e-158	549.00
IUUC-Pma-094568	Petromyzon marinus	61.46	2.00e-107	381.00
IUUC-Pno-095120	Phaeosphaeria nodorum	44.16	6.00e-48	184.00
IUUC-Ppa-095761	Physcomitrella patens	46.49	8.00e-84	303.00
IUUC-Pfo-096210	Poecilia formosa	99.68	0.00e+00	649.00
IUUC-Pab-098463	Pongo abelii	89.14	3.00e-171	594.00
IUUC-Pop-099423	Populus trichocarpa	48.66	2.00e-85	308.00
IUUC-Pca-100108	Procavia capensis	87.80	3.00e-131	461.00
IUUC-Ppe-101176	Prunus persica	50.60	1.00e-84	306.00
IUUC-Pva-102629	Pteropus vampyrus	87.02	2.00e-136	478.00
IUUC-Pgr-103419	Puccinia graminis	44.13	3.00e-54	205.00
IUUC-Pte-104207	Pyrenophora teres	41.42	2.00e-30	124.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	37.70	7.00e-54	204.00
IUUC-Rno-105579	Rattus norvegicus	78.02	3.00e-148	517.00
IUUC-Sha-106894	Sarcophilus harrisii	86.59	1.00e-144	505.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	39.66	2.00e-58	218.00
IUUC-Spo-108371	Schizosaccharomyces pombe	40.12	7.00e-60	223.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	37.32	5.00e-47	181.00
IUUC-Smo-109396	Selaginella moellendorffii	51.38	1.00e-87	315.00
IUUC-Sit-110630	Setaria italica	50.15	1.00e-86	312.00
IUUC-Sly-110972	Solanum lycopersicum	49.20	7.00e-81	293.00
IUUC-Stu-112185	Solanum tuberosum	48.80	3.00e-89	321.00
IUUC-Sar-113294	Sorex araneus	73.79	1.00e-149	522.00
IUUC-Sbi-113951	Sorghum bicolor	50.46	9.00e-87	313.00
IUUC-Ssc-115501	Sus scrofa	87.88	7.00e-159	552.00
IUUC-Tgu-117152	Taeniopygia guttata	89.24	2.00e-151	528.00
IUUC-Tru-118388	Takifugu rubripes	93.29	4.00e-178	617.00
IUUC-Tsy-119109	Tarsius syrichta	89.46	5.00e-172	596.00
IUUC-Tni-120048	Tetraodon nigroviridis	93.61	3.00e-179	620.00
IUUC-Tca-121750	Theobroma cacao	49.70	3.00e-89	321.00
IUUC-Tre-122130	Trichoderma reesei	39.33	5.00e-55	207.00
IUUC-Tvi-122284	Trichoderma virens	39.80	1.00e-51	196.00
IUUC-Tae-124082	Triticum aestivum	47.56	5.00e-82	297.00
IUUC-Tur-126366	Triticum urartu	42.69	2.00e-65	243.00
IUUC-Tme-127187	Tuber melanosporum	38.62	3.00e-59	221.00
IUUC-Tbe-127619	Tupaia belangeri	80.49	3.00e-130	457.00
IUUC-Ttr-128867	Tursiops truncatus	80.00	1.00e-114	406.00
IUUC-Vda-129912	Verticillium dahliae	37.84	2.00e-53	202.00
IUUC-Vpa-130552	Vicugna pacos	90.43	7.00e-117	413.00
IUUC-Vvi-130881	Vitis vinifera	49.55	7.00e-84	303.00
IUUC-Xtr-131934	Xenopus tropicalis	83.59	2.00e-169	588.00
IUUC-Yli-134487	Yarrowia lipolytica	32.02	2.00e-45	176.00
IUUC-Zma-135462	Zea mays	43.69	2.00e-72	266.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence