iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Dme-031635

UUCD1 version

UUC-DrM-00576

Ensembl Protein ID

FBpp0076859

UniProt Accession

Q9VRL1; Q9VRL1_DROME

Genbank Protein ID

AAF50784.1; AAL25423.1; AHN57965.1; ANY27675.1

Protein Name

GEO06356p1; LD28904p; Ubiquitin-conjugating enzyme variant 1A, isoform A; Ubiquitin-conjugating enzyme variant 1A, isoform C

Genbank Nucleotide ID

AE014296; AY060384; AE014296; KX531865

Gene Name

Uev1A; DmelCG10640; DmUEV; dUEV1A; dUEV1a; dUev1A; UEV; UEV1A; UEV1a; Uev1a; uev1a; CG10640; Dmel_CG

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0035601	FBtr0077155	FBpp0076859

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UEV	1.50e-56	190.3	4	145
E2/UBC	1.50e-18	66.9	33	131

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E2/UEV

   S: 4    eselkvvvprnfrlleeleegekglgdgtvsygldDgddilllsltgtIigpertayegrIyqlklfvgkkYPekPPtvrfsskinmaevndsnGvvd 101
           +s + vvvprnfrlleel +g+kg+gdgt+s+gl+ +dd++l+ + g+Iigp+rt  e+r+y+lk+++g++YP +PPt rf +k+n++++n++nGvvd
   Q: 4    TSSTGVVVPRNFRLLEELDQGQKGVGDGTISWGLENDDDMTLTYWIGMIIGPPRTPFENRMYSLKIECGERYPDEPPTLRFITKVNINCINQNNGVVD 101
           56789********************************************************************************************* PP
   S: 102  pralpvLanWkreysievvlvqlkkellskenrklqqPpeGnlf 145
           +r++ +La+W+rey i+++l+++++ +  ken kl+qPpeG++f
   Q: 102  HRSVQMLARWSREYNIKTMLQEIRRIMTMKENLKLAQPPEGSCF 145
           ******************************************97 PP

E2/UBC

   S: 17   isakpvdesd..ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsvesvllsiqsllae 111
           is ++++++d  lt w  +i+Gp++tp+e+++++l+ie+ e+YP +PP+++f+tk+   ++++n G v    ++   +Ws  +++++ l +i ++++ 
   Q: 33   ISWGLENDDDmtLTYWIGMIIGPPRTPFENRMYSLKIECGERYPDEPPTLRFITKVNINCINQNnGVVDHRSVQMLARWSREYNIKTMLQEIRRIMTM 130
           45555555555599*****************************************9999999887999766666678*****************9964 PP
   S: 112  p 112
            
   Q: 131  K 131
           3 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MANTSSTGVV VPRNFRLLEE LDQGQKGVGD GTISWGLEND DDMTLTYWIG MIIGPPRTPF 60
ENRMYSLKIE CGERYPDEPP TLRFITKVNI NCINQNNGVV DHRSVQMLAR WSREYNIKTM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGGTCACA TCGCACTGGA AACGCGTTAG CACACTTTTA CGGTATTTTA GCACTTAGCA 60
TTAACCACAA TGGCGAATAC ATCAAGTACC GGCGTTGGTA AGAAATAAAA TTGATAAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0035370--C:UBC13-UEV1A complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0031625--F:ubiquitin protein ligase binding
GO:0061057--P:peptidoglycan recognition protein signaling pathway
GO:0006301--P:postreplication repair
GO:0070534--P:protein K63-linked ubiquitination
GO:0000209--P:protein polyubiquitination

KEGG

dme:Dmel_CG10640

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000636	Aegilops tauschii	49.25	4.00e-35	140.00
IUUC-Aml-001242	Ailuropoda melanoleuca	67.86	9.00e-53	199.00
IUUC-Atr-003005	Amborella trichopoda	46.48	6.00e-37	145.00
IUUC-Apl-003600	Anas platyrhynchos	68.12	1.00e-52	197.00
IUUC-Aca-005104	Anolis carolinensis	66.90	2.00e-57	213.00
IUUC-Aly-005402	Arabidopsis lyrata	48.95	4.00e-38	149.00
IUUC-Ath-006915	Arabidopsis thaliana	47.52	2.00e-37	147.00
IUUC-Ago-007810	Ashbya gossypii	48.89	2.00e-33	133.00
IUUC-Acl-008375	Aspergillus clavatus	51.45	2.00e-32	130.00
IUUC-Afl-008598	Aspergillus flavus	49.63	7.00e-32	128.00
IUUC-Afu-008838	Aspergillus fumigatus	51.85	6.00e-34	135.00
IUUC-Ani-009325	Aspergillus nidulans	49.29	3.00e-34	136.00
IUUC-Ang-009631	Aspergillus niger	49.63	1.00e-32	130.00
IUUC-Aor-010051	Aspergillus oryzae	49.63	7.00e-32	128.00
IUUC-Ate-010471	Aspergillus terreus	48.54	3.00e-28	115.00
IUUC-Ame-010710	Astyanax mexicanus	64.14	5.00e-57	212.00
IUUC-Bgr-012010	Blumeria graminis	49.63	5.00e-33	132.00
IUUC-Bta-013403	Bos taurus	66.90	8.00e-55	204.00
IUUC-Bci-013649	Botrytis cinerea	48.89	2.00e-28	117.00
IUUC-Bdi-014826	Brachypodium distachyon	47.22	2.00e-38	150.00
IUUC-Bol-015323	Brassica oleracea	49.30	1.00e-39	154.00
IUUC-Bra-018041	Brassica rapa	49.30	1.00e-39	154.00
IUUC-Cel-018398	Caenorhabditis elegans	63.77	2.00e-45	172.00
IUUC-Cja-019316	Callithrix jacchus	66.90	8.00e-55	204.00
IUUC-Cfa-021118	Canis familiaris	66.90	1.00e-52	197.00
IUUC-Cpo-021317	Cavia porcellus	66.67	4.00e-56	209.00
IUUC-Cre-022629	Chlamydomonas reinhardtii	50.36	2.00e-38	149.00
IUUC-Csa-024275	Chlorocebus sabaeus	67.86	9.00e-53	199.00
IUUC-Cho-025024	Choloepus hoffmanni	56.82	8.00e-30	120.00
IUUC-Cin-025219	Ciona intestinalis	47.66	4.00e-26	108.00
IUUC-Cgl-026596	Colletotrichum gloeosporioides	50.72	8.00e-34	134.00
IUUC-Cne-026817	Cryptococcus neoformans	46.67	9.00e-38	148.00
IUUC-Cme-027257	Cyanidioschyzon merolae	51.82	2.00e-25	107.00
IUUC-Dre-028019	Danio rerio	64.83	2.00e-57	213.00
IUUC-Dno-029762	Dasypus novemcinctus	67.63	6.00e-53	198.00
IUUC-Dor-030185	Dipodomys ordii	82.69	1.00e-21	95.10
IUUC-Dse-031272	Dothistroma septosporum	52.17	2.00e-33	133.00
IUUC-Ete-033017	Echinops telfairi	62.86	2.00e-49	188.00
IUUC-Eca-034422	Equus caballus	65.28	3.00e-52	196.00
IUUC-Eeu-035327	Erinaceus europaeus	67.86	4.00e-53	201.00
IUUC-Fca-035746	Felis catus	66.67	3.00e-56	209.00
IUUC-Fal-037350	Ficedula albicollis	64.83	4.00e-53	199.00
IUUC-Fox-037803	Fusarium oxysporum	51.85	6.00e-35	138.00
IUUC-Fso-038147	Fusarium solani	51.11	1.00e-33	134.00
IUUC-Gmo-039237	Gadus morhua	63.45	4.00e-55	205.00
IUUC-Ggr-039839	Gaeumannomyces graminis	40.94	2.00e-23	100.00
IUUC-Gga-040746	Gallus gallus	66.43	3.00e-52	196.00
IUUC-Gac-041936	Gasterosteus aculeatus	63.38	5.00e-47	178.00
IUUC-Gma-043467	Glycine max	52.45	1.00e-38	151.00
IUUC-Ggo-044696	Gorilla gorilla	67.14	1.00e-57	214.00
IUUC-Hsa-045659	Homo sapiens	66.90	8.00e-55	204.00
IUUC-Hvu-047307	Hordeum vulgare	47.22	6.00e-39	152.00
IUUC-Itr-048139	Ictidomys tridecemlineatus	68.12	1.00e-52	197.00
IUUC-Kpa-049337	Komagataella pastoris	47.06	2.00e-31	127.00
IUUC-Lch-050494	Latimeria chalumnae	65.00	6.00e-56	208.00
IUUC-Lpe-050874	Leersia perrieri	48.51	4.00e-37	145.00
IUUC-Loc-052012	Lepisosteus oculatus	66.20	3.00e-57	212.00
IUUC-Lma-053194	Leptosphaeria maculans	50.00	9.00e-34	134.00
IUUC-Laf-054176	Loxodonta africana	66.90	8.00e-55	204.00
IUUC-Mcc-055788	Macaca mulatta	67.86	9.00e-53	199.00
IUUC-Meu-056842	Macropus eugenii	52.27	5.00e-21	94.40
IUUC-Mor-056915	Magnaporthe oryzae	33.55	2.00e-19	87.40
IUUC-Mpo-057437	Magnaporthe poae	40.94	2.00e-23	100.00
IUUC-Mtr-058655	Medicago truncatula	51.06	4.00e-37	145.00
IUUC-Mla-058919	Melampsora laricipopulina	51.80	1.00e-31	127.00
IUUC-Mga-059951	Meleagris gallopavo	64.83	7.00e-53	198.00
IUUC-Mvi-060260	Microbotryum violaceum	49.63	9.00e-33	131.00
IUUC-Mmr-061751	Microcebus murinus	65.00	2.00e-55	206.00
IUUC-Mdo-062503	Monodelphis domestica	68.57	4.00e-53	199.00
IUUC-Mmu-063294	Mus musculus	67.14	6.00e-58	215.00
IUUC-Mac-065220	Musa acuminata	46.21	1.00e-38	150.00
IUUC-Mpu-065775	Mustela putorius furo	66.90	8.00e-55	204.00
IUUC-Mlu-067702	Myotis lucifugus	66.67	3.00e-56	209.00
IUUC-Nfi-068400	Neosartorya fischeri	50.54	2.00e-26	109.00
IUUC-Ncr-068946	Neurospora crassa	42.28	5.00e-32	129.00
IUUC-Nle-069245	Nomascus leucogenys	66.90	8.00e-55	204.00
IUUC-Opr-070859	Ochotona princeps	62.79	9.00e-46	176.00
IUUC-Ont-072098	Oreochromis niloticus	64.79	4.00e-48	182.00
IUUC-Oan-073215	Ornithorhynchus anatinus	64.58	3.00e-49	186.00
IUUC-Ocu-073859	Oryctolagus cuniculus	67.14	1.00e-57	214.00
IUUC-Oba-075005	Oryza barthii	47.76	2.00e-36	144.00
IUUC-Obr-076228	Oryza brachyantha	49.64	5.00e-39	152.00
IUUC-Ogl-077309	Oryza glaberrima	48.20	1.00e-38	150.00
IUUC-Ogu-078374	Oryza glumaepatula	47.76	2.00e-36	144.00
IUUC-Oin-079314	Oryza indica	48.20	1.00e-38	150.00
IUUC-Olo-080528	Oryza longistaminata	47.26	2.00e-37	146.00
IUUC-Ome-081761	Oryza meridionalis	47.76	8.00e-37	145.00
IUUC-Oni-082956	Oryza nivara	48.20	1.00e-38	150.00
IUUC-Opu-083148	Oryza punctata	47.76	2.00e-36	144.00
IUUC-Oru-084710	Oryza rufipogon	48.20	1.00e-38	150.00
IUUC-Osa-085558	Oryza sativa	48.20	1.00e-38	150.00
IUUC-Ola-087529	Oryzias latipes	65.54	8.00e-49	184.00
IUUC-Olu-087815	Ostreococcus lucimarinus	37.84	3.00e-18	83.20
IUUC-Oga-087972	Otolemur garnettii	68.12	1.00e-52	197.00
IUUC-Oar-090166	Ovis aries	67.86	6.00e-53	200.00
IUUC-Ptr-090866	Pan troglodytes	66.90	8.00e-55	204.00
IUUC-Pan-091955	Papio anubis	67.14	1.00e-57	214.00
IUUC-Psi-093138	Pelodiscus sinensis	65.96	2.00e-51	193.00
IUUC-Pma-094142	Petromyzon marinus	69.39	5.00e-17	77.80
IUUC-Pno-095070	Phaeosphaeria nodorum	50.72	5.00e-34	135.00
IUUC-Ppa-095557	Physcomitrella patens	48.23	3.00e-36	142.00
IUUC-Pfo-096483	Poecilia formosa	64.79	3.00e-48	182.00
IUUC-Pab-098403	Pongo abelii	67.86	8.00e-53	199.00
IUUC-Pop-099786	Populus trichocarpa	47.18	1.00e-38	150.00
IUUC-Pca-100723	Procavia capensis	67.86	7.00e-53	200.00
IUUC-Ppe-101725	Prunus persica	51.43	9.00e-39	151.00
IUUC-Pva-102989	Pteropus vampyrus	67.14	1.00e-57	214.00
IUUC-Pgr-103617	Puccinia graminis	52.52	2.00e-31	127.00
IUUC-Ptt-104008	Puccinia triticina	47.06	6.00e-17	79.00
IUUC-Pte-104176	Pyrenophora teres	50.00	4.00e-34	135.00
IUUC-Pyt-104517	Pyrenophora triticirepentis	50.00	4.00e-34	135.00
IUUC-Rno-106065	Rattus norvegicus	64.83	1.00e-52	197.00
IUUC-Sce-106349	Saccharomyces cerevisiae	48.89	5.00e-30	122.00
IUUC-Sha-107363	Sarcophilus harrisii	66.21	9.00e-54	201.00
IUUC-Sja-107722	Schizosaccharomyces japonicus	48.89	1.00e-29	121.00
IUUC-Spo-108027	Schizosaccharomyces pombe	45.93	2.00e-28	117.00
IUUC-Ssl-108493	Sclerotinia sclerotiorum	48.23	9.00e-30	121.00
IUUC-Smo-109381	Selaginella moellendorffii	43.80	3.00e-37	146.00
IUUC-Sit-110302	Setaria italica	46.53	2.00e-38	150.00
IUUC-Sly-111205	Solanum lycopersicum	47.18	2.00e-38	150.00
IUUC-Stu-112459	Solanum tuberosum	46.48	5.00e-38	148.00
IUUC-Sar-113197	Sorex araneus	73.63	2.00e-38	151.00
IUUC-Sbi-114210	Sorghum bicolor	46.53	2.00e-38	150.00
IUUC-Sre-114909	Sporisorium reilianum	45.19	2.00e-30	123.00
IUUC-Ssc-115939	Sus scrofa	66.90	8.00e-55	204.00
IUUC-Tgu-117289	Taeniopygia guttata	67.86	4.00e-53	199.00
IUUC-Tru-118526	Takifugu rubripes	65.69	5.00e-42	162.00
IUUC-Tsy-119103	Tarsius syrichta	73.40	8.00e-40	155.00
IUUC-Tni-120169	Tetraodon nigroviridis	64.54	5.00e-43	165.00
IUUC-Tca-121025	Theobroma cacao	51.43	9.00e-39	152.00
IUUC-Tre-121971	Trichoderma reesei	51.85	1.00e-35	140.00
IUUC-Tvi-122622	Trichoderma virens	51.85	2.00e-35	140.00
IUUC-Tae-123682	Triticum aestivum	47.22	8.00e-39	151.00
IUUC-Tur-126083	Triticum urartu	48.53	2.00e-37	146.00
IUUC-Tme-127171	Tuber melanosporum	46.67	4.00e-29	119.00
IUUC-Tbe-128105	Tupaia belangeri	67.15	4.00e-55	207.00
IUUC-Ttr-128790	Tursiops truncatus	67.86	6.00e-53	200.00
IUUC-Uma-129419	Ustilago maydis	46.67	3.00e-31	126.00
IUUC-Vda-129776	Verticillium dahliae	51.82	1.00e-33	134.00
IUUC-Vpa-130575	Vicugna pacos	67.88	2.00e-51	195.00
IUUC-Vvi-130831	Vitis vinifera	51.43	1.00e-39	154.00
IUUC-Xtr-132359	Xenopus tropicalis	66.21	1.00e-53	200.00
IUUC-Xma-133222	Xiphophorus maculatus	64.79	5.00e-48	182.00
IUUC-Yli-134591	Yarrowia lipolytica	49.50	8.00e-28	114.00
IUUC-Zma-135558	Zea mays	47.01	8.00e-36	141.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence