iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000075798.3	ENSDART00000158799.1	ENSDARP00000135358.1
ENSDARG00000075798.3	ENSDART00000109678.3	ENSDARP00000101307.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-75	255.7	445	920

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNS+LQ L++ +++r+ + +    +ln +      ++l+k+lq lf+ l ++++ a+spr++l++ + +   fs  +q
   Q: 445  TGLVNLGNTCYMNSILQILFMATDFRRHVMS---LQLNGS------NTLMKKLQLLFAFLAHTQRAAYSPRSFLDVSRPTW--FSAGSQ 522
           7******************************...677765......59****************************99554..99**** PP
   S: 90   qDaqEflaflldqleeelkk....eknkpkeeeeeedkselsde................aeekkkkknkslisdlFqgqlksqikcle 158
           qD++E+l+flld+l+ee k     +    + + + e  +++++                  +   + ++ +l++++F+g+l++ i+cl+
   Q: 523  QDCSEYLRFLLDRLHEEEKAlsalQ----TASPKPEPATTSPETlhnavsppisdvpshpDPAAAQGETGTLVERMFGGRLSTAIRCLQ 607
           ******************7755542....22222222223333355567788899999776666777777******************* PP
   S: 159  cdnvssreepfldlslpvpgkeetkke...............................................slqdcLesftkeeel 200
           c++ s++eepf+dlsl++  + ++ ++                                               s+ d+ + f ++e l
   Q: 608  CHSLSEKEEPFTDLSLAFCPSMSQ-PRgptnehkssstlgpcqgavnggseasegpvkegaasgmerpmveptiSVPDLVDYFLAPEIL 695
           ******************977744.336788999999**************************************************** PP
   S: 201  egenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke............... 274
           e+en y+ce+c ++q+aek +++   Pe+Lil L Rfs++ + ++r+ki ++v +pl+++l  + +s+++++++               
   Q: 696  ENENCYFCERCASLQRAEKAMRVVAAPEYLILTLLRFSYDATCHVRRKILDNVGIPLHMSLPLHQHSSSSSSNVaassstespdscenl 784
           ********************************************************987776555554444433567778888888888 PP
   S: 275  ..............................kkkYeLiavvvHsG.slssGHYvayvkn............................... 301
                                         ++ Y L++vv+HsG s++sGHY++y +n                               
   Q: 785  akklkpsqkeegiaesrmkskknnsdlqklSVPYVLSSVVMHSGmSSDSGHYYSYGRNvssddgcvahtspksldnssqsesstapqee 873
           888888888888888888888999999999************************************************99999999988 PP
   S: 302  ......ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                 ++ +W+lf+Ds+Vt ++ ++ ++ t+    +taYvl+Y+++
   Q: 874  tgradpKSADWFLFNDSRVTFTNFQSLQNVTSrfpkDTAYVLIYRKQ 920
           8777666666*******************999************986 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MDKILEALVS SSHPQNVKRA IVKKVMEAAE KEVTEEQCQA LYHLTTRLIL QGEDVFQRQI 60
GFQVQEAYAR YHRDEFARFF SKEFVLGLLQ QGYGSLDHRD PAILDFIHSS LRLLISCPAV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGATTTT GGACGCACCA AATGTGTGGG GTGCAAGTGT TGGGTCCTGA CATCATTCTC 60
GCGCGTTTTG ATGACGTTTG TGTGTTTCAA CAGCTGATTG AAAGAGGTCG CAGTTTAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

dre:563778

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	62.38	0.00e+00	1165.00
IUUC-Apl-003435	Anas platyrhynchos	60.31	0.00e+00	964.00
IUUC-Aca-004556	Anolis carolinensis	58.84	0.00e+00	1073.00
IUUC-Ame-010616	Astyanax mexicanus	76.73	0.00e+00	1536.00
IUUC-Bta-013544	Bos taurus	62.39	0.00e+00	1165.00
IUUC-Cja-018745	Callithrix jacchus	61.13	0.00e+00	1190.00
IUUC-Cfa-020434	Canis familiaris	62.30	0.00e+00	1159.00
IUUC-Cpo-021666	Cavia porcellus	61.36	0.00e+00	1134.00
IUUC-Csa-023965	Chlorocebus sabaeus	62.81	0.00e+00	1229.00
IUUC-Cho-024809	Choloepus hoffmanni	54.22	0.00e+00	749.00
IUUC-Cin-025604	Ciona intestinalis	37.39	1.00e-40	160.00
IUUC-Csv-026333	Ciona savignyi	42.31	1.00e-32	133.00
IUUC-Dno-029372	Dasypus novemcinctus	62.14	0.00e+00	1197.00
IUUC-Dor-030752	Dipodomys ordii	58.63	0.00e+00	727.00
IUUC-Dme-031871	Drosophila melanogaster	26.71	2.00e-65	244.00
IUUC-Ete-032588	Echinops telfairi	54.18	0.00e+00	699.00
IUUC-Eca-034416	Equus caballus	62.46	0.00e+00	1217.00
IUUC-Eeu-035132	Erinaceus europaeus	49.81	0.00e+00	861.00
IUUC-Fca-036137	Felis catus	62.24	0.00e+00	1207.00
IUUC-Fal-037297	Ficedula albicollis	59.74	0.00e+00	1122.00
IUUC-Gmo-038727	Gadus morhua	72.99	0.00e+00	1115.00
IUUC-Gga-041091	Gallus gallus	58.59	0.00e+00	1094.00
IUUC-Gac-042082	Gasterosteus aculeatus	70.21	0.00e+00	1266.00
IUUC-Ggo-045376	Gorilla gorilla	59.38	0.00e+00	1113.00
IUUC-Hsa-046444	Homo sapiens	62.90	0.00e+00	1229.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	62.31	0.00e+00	1216.00
IUUC-Lch-050500	Latimeria chalumnae	60.50	0.00e+00	1199.00
IUUC-Loc-052625	Lepisosteus oculatus	66.89	0.00e+00	1361.00
IUUC-Laf-053689	Loxodonta africana	61.85	0.00e+00	1199.00
IUUC-Mcc-055286	Macaca mulatta	62.49	0.00e+00	1219.00
IUUC-Meu-056906	Macropus eugenii	49.60	0.00e+00	632.00
IUUC-Mga-059905	Meleagris gallopavo	58.34	0.00e+00	946.00
IUUC-Mmr-061397	Microcebus murinus	62.71	0.00e+00	1181.00
IUUC-Mdo-062833	Monodelphis domestica	62.02	0.00e+00	1245.00
IUUC-Mmu-063157	Mus musculus	62.18	0.00e+00	1162.00
IUUC-Mpu-066434	Mustela putorius furo	62.62	0.00e+00	1218.00
IUUC-Mlu-068178	Myotis lucifugus	62.10	0.00e+00	1149.00
IUUC-Nle-070153	Nomascus leucogenys	62.15	0.00e+00	1164.00
IUUC-Opr-070454	Ochotona princeps	46.00	2.00e-72	267.00
IUUC-Ont-072330	Oreochromis niloticus	69.28	0.00e+00	1375.00
IUUC-Oan-072709	Ornithorhynchus anatinus	61.11	0.00e+00	935.00
IUUC-Ocu-074832	Oryctolagus cuniculus	62.82	0.00e+00	1185.00
IUUC-Ola-087003	Oryzias latipes	59.90	3.00e-56	211.00
IUUC-Oga-088517	Otolemur garnettii	61.73	0.00e+00	1167.00
IUUC-Oar-089472	Ovis aries	60.13	0.00e+00	1093.00
IUUC-Ptr-090996	Pan troglodytes	62.51	0.00e+00	1228.00
IUUC-Pan-091837	Papio anubis	61.46	0.00e+00	1185.00
IUUC-Psi-093236	Pelodiscus sinensis	61.36	0.00e+00	876.00
IUUC-Pma-094349	Petromyzon marinus	52.18	0.00e+00	947.00
IUUC-Pfo-097193	Poecilia formosa	68.40	0.00e+00	1280.00
IUUC-Pab-098710	Pongo abelii	62.49	0.00e+00	1244.00
IUUC-Pca-100794	Procavia capensis	55.66	0.00e+00	1014.00
IUUC-Pva-102722	Pteropus vampyrus	62.67	0.00e+00	1211.00
IUUC-Rno-105743	Rattus norvegicus	61.77	0.00e+00	1159.00
IUUC-Sha-106563	Sarcophilus harrisii	61.55	0.00e+00	1004.00
IUUC-Sar-113533	Sorex araneus	54.58	0.00e+00	996.00
IUUC-Ssc-116259	Sus scrofa	74.65	0.00e+00	785.00
IUUC-Tgu-117475	Taeniopygia guttata	59.75	0.00e+00	1018.00
IUUC-Tru-118623	Takifugu rubripes	66.76	0.00e+00	1248.00
IUUC-Tsy-119250	Tarsius syrichta	60.62	0.00e+00	891.00
IUUC-Tni-120441	Tetraodon nigroviridis	64.29	0.00e+00	1194.00
IUUC-Tbe-127936	Tupaia belangeri	52.87	0.00e+00	885.00
IUUC-Ttr-128483	Tursiops truncatus	52.51	0.00e+00	818.00
IUUC-Vpa-130303	Vicugna pacos	74.16	0.00e+00	835.00
IUUC-Xtr-132773	Xenopus tropicalis	61.03	0.00e+00	1174.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence