iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000032244.2	ENSCAFT00000045869.2	ENSCAFP00000041429.1
ENSCAFG00000032244.2	ENSCAFT00000045225.1	ENSCAFP00000039450.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UEV	3.80e-67	224.9	19	157
E2/UBC	1.40e-19	70.5	44	150

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E2/UEV

   S: 7    lkvvvprnfrlleeleegekglgdgtvsygldDgddilllsltgtIigpertayegrIyqlklfvgkkYPekPPtvrfsskinmaevnd 95
           l v+vprnfrlleeleeg+kg+gdgtvs+gl+D++d++l+++tg+Iigp+rt ye+rIy+lk+++g+kYPe+PP+vrf++kinm++vn+
   Q: 19   LGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNS 107
           579************************************************************************************** PP
   S: 96   snGvvdpralpvLanWkreysievvlvqlkkellskenrklqqPpeGnlf 145
           snGvvdpra++vLa+W+++ysi+vvl++l++ ++sken+kl+qPpeG+++
   Q: 108  SNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCY 157
           ************************************************98 PP

E2/UBC

   S: 16   gisakpvdesd..ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.Gkv...ClsilkeeekWspalsv 98
           ++s +++d++d  lt+w  +i+Gp++t+Ye+++++l+ie+ ++YP  PP v+f+tki    v+++ G v    +s+l    kW+  +s+
   Q: 44   TVSWGLEDDEDmtLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSnGVVdprAISVL---AKWQNSYSI 129
           456667777776689*****************************************999999988798866668888...5******** PP
   S: 99   esvllsiqsll.aepnpespl 118
           + vl ++ +l+ ++ n++ p+
   Q: 130  KVVLQELRRLMmSKENMKLPQ 150
           *********996667777665 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

LVVFICSGPK LINILTFILG VKVPRNFRLL EELEEGQKGV GDGTVSWGLE DDEDMTLTRW 60
TGMIIGPPRT IYENRIYSLK IECGPKYPEA PPFVRFVTKI NMNGVNSSNG VVDPRAISVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGACAGCGA CGCAAGATGG CAGCCACCAC GGGCTCGGGT GAGCTGGGGC GCCGGGCCCG 60
GCTGGCCAAG GGGGCGCGGG CTTGGGCCGG GGACCGAGGA CCCGCAAAGG TCCCGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0035370--C:UBC13-UEV1A complex
GO:0000151--C:ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006301--P:postreplication repair
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000910	Aegilops tauschii	55.15	3.00e-39	153.00
IUUC-Aml-001242	Ailuropoda melanoleuca	100.00	2.00e-73	269.00
IUUC-Atr-003059	Amborella trichopoda	53.03	7.00e-38	149.00
IUUC-Apl-003600	Anas platyrhynchos	98.60	9.00e-74	268.00
IUUC-Aca-005104	Anolis carolinensis	98.58	9.00e-79	285.00
IUUC-Aly-005402	Arabidopsis lyrata	54.35	8.00e-39	152.00
IUUC-Ath-006915	Arabidopsis thaliana	54.48	8.00e-38	149.00
IUUC-Ago-007810	Ashbya gossypii	52.21	2.00e-34	137.00
IUUC-Acl-008375	Aspergillus clavatus	48.92	8.00e-33	132.00
IUUC-Afl-008598	Aspergillus flavus	50.74	2.00e-34	137.00
IUUC-Afu-008838	Aspergillus fumigatus	49.26	2.00e-34	137.00
IUUC-Aor-010051	Aspergillus oryzae	50.74	2.00e-34	137.00
IUUC-Ame-010710	Astyanax mexicanus	90.00	3.00e-73	266.00
IUUC-Bgr-012010	Blumeria graminis	50.71	4.00e-33	133.00
IUUC-Bta-013403	Bos taurus	100.00	1.00e-73	267.00
IUUC-Bci-013649	Botrytis cinerea	51.45	5.00e-33	132.00
IUUC-Bdi-014636	Brachypodium distachyon	53.73	5.00e-38	149.00
IUUC-Bol-015323	Brassica oleracea	54.01	1.00e-39	155.00
IUUC-Bra-018041	Brassica rapa	54.01	1.00e-39	155.00
IUUC-Cel-018398	Caenorhabditis elegans	66.67	5.00e-48	182.00
IUUC-Cja-019316	Callithrix jacchus	100.00	1.00e-73	267.00
IUUC-Cre-022629	Chlamydomonas reinhardtii	48.92	4.00e-38	149.00
IUUC-Csa-024275	Chlorocebus sabaeus	100.00	2.00e-73	268.00
IUUC-Cgl-026596	Colletotrichum gloeosporioides	53.24	4.00e-37	146.00
IUUC-Cne-026817	Cryptococcus neoformans	50.00	4.00e-37	146.00
IUUC-Cme-027257	Cyanidioschyzon merolae	56.30	2.00e-28	117.00
IUUC-Dre-028019	Danio rerio	89.29	4.00e-73	266.00
IUUC-Dno-029762	Dasypus novemcinctus	100.00	3.00e-73	266.00
IUUC-Dme-031635	Drosophila melanogaster	68.12	2.00e-57	214.00
IUUC-Ete-033017	Echinops telfairi	88.97	2.00e-70	259.00
IUUC-Eca-034422	Equus caballus	100.00	1.00e-72	265.00
IUUC-Eeu-035327	Erinaceus europaeus	100.00	8.00e-74	270.00
IUUC-Fal-037350	Ficedula albicollis	99.30	1.00e-73	268.00
IUUC-Fox-037803	Fusarium oxysporum	51.80	5.00e-37	146.00
IUUC-Fso-038147	Fusarium solani	53.57	2.00e-38	150.00
IUUC-Gmo-039237	Gadus morhua	83.45	2.00e-68	250.00
IUUC-Gga-040746	Gallus gallus	97.86	7.00e-72	262.00
IUUC-Gma-043736	Glycine max	55.22	7.00e-42	162.00
IUUC-Ggo-045491	Gorilla gorilla	97.86	1.00e-69	256.00
IUUC-Hsa-045659	Homo sapiens	100.00	1.00e-73	267.00
IUUC-Hvu-047368	Hordeum vulgare	54.48	3.00e-38	150.00
IUUC-Itr-048139	Ictidomys tridecemlineatus	100.00	7.00e-75	271.00
IUUC-Kpa-049337	Komagataella pastoris	51.11	8.00e-32	129.00
IUUC-Lch-050494	Latimeria chalumnae	87.86	1.00e-72	264.00
IUUC-Lpe-050874	Leersia perrieri	54.48	2.00e-38	150.00
IUUC-Loc-052024	Lepisosteus oculatus	89.29	7.00e-73	267.00
IUUC-Laf-054176	Loxodonta africana	100.00	1.00e-73	267.00
IUUC-Mcc-055788	Macaca mulatta	100.00	2.00e-73	269.00
IUUC-Meu-056842	Macropus eugenii	85.56	3.00e-35	142.00
IUUC-Mor-056915	Magnaporthe oryzae	38.41	5.00e-21	93.60
IUUC-Mpo-057437	Magnaporthe poae	46.71	1.00e-29	122.00
IUUC-Mtr-058655	Medicago truncatula	54.68	7.00e-38	149.00
IUUC-Mga-059951	Meleagris gallopavo	96.53	4.00e-73	266.00
IUUC-Mvi-060260	Microbotryum violaceum	54.01	9.00e-37	145.00
IUUC-Mmr-061374	Microcebus murinus	93.57	1.00e-60	224.00
IUUC-Mmu-063234	Mus musculus	93.57	1.00e-68	253.00
IUUC-Mac-065351	Musa acuminata	53.62	8.00e-39	152.00
IUUC-Mpu-065775	Mustela putorius furo	100.00	1.00e-73	267.00
IUUC-Mlu-067269	Myotis lucifugus	91.67	2.00e-71	261.00
IUUC-Nfi-068400	Neosartorya fischeri	44.21	2.00e-26	110.00
IUUC-Ncr-068946	Neurospora crassa	46.36	1.00e-36	144.00
IUUC-Nle-069245	Nomascus leucogenys	100.00	1.00e-73	267.00
IUUC-Opr-070859	Ochotona princeps	87.86	3.00e-63	235.00
IUUC-Ocu-074447	Oryctolagus cuniculus	97.89	2.00e-73	267.00
IUUC-Obr-076191	Oryza brachyantha	54.01	9.00e-39	152.00
IUUC-Olu-087815	Ostreococcus lucimarinus	42.11	3.00e-20	90.90
IUUC-Oga-087972	Otolemur garnettii	100.00	7.00e-75	271.00
IUUC-Oar-090166	Ovis aries	100.00	1.00e-73	270.00
IUUC-Ptr-090866	Pan troglodytes	100.00	1.00e-73	267.00
IUUC-Pan-092804	Papio anubis	97.14	5.00e-71	259.00
IUUC-Ppa-095557	Physcomitrella patens	54.01	2.00e-39	154.00
IUUC-Pab-098403	Pongo abelii	100.00	1.00e-73	269.00
IUUC-Pop-099786	Populus trichocarpa	52.74	8.00e-39	152.00
IUUC-Pca-100723	Procavia capensis	100.00	1.00e-73	270.00
IUUC-Ppe-101725	Prunus persica	56.72	6.00e-39	152.00
IUUC-Pva-102393	Pteropus vampyrus	98.57	4.00e-79	288.00
IUUC-Rno-106065	Rattus norvegicus	93.57	5.00e-69	252.00
IUUC-Sha-107363	Sarcophilus harrisii	100.00	5.00e-74	269.00
IUUC-Sja-107722	Schizosaccharomyces japonicus	54.01	1.00e-34	138.00
IUUC-Spo-108027	Schizosaccharomyces pombe	51.09	2.00e-33	134.00
IUUC-Ssl-108493	Sclerotinia sclerotiorum	53.96	1.00e-34	138.00
IUUC-Smo-109006	Selaginella moellendorffii	46.72	2.00e-29	120.00
IUUC-Sit-110302	Setaria italica	55.80	3.00e-40	157.00
IUUC-Sly-111205	Solanum lycopersicum	53.28	4.00e-39	153.00
IUUC-Stu-112459	Solanum tuberosum	52.55	1.00e-38	152.00
IUUC-Sbi-114210	Sorghum bicolor	55.07	1.00e-39	154.00
IUUC-Sre-114909	Sporisorium reilianum	51.82	1.00e-33	135.00
IUUC-Ssc-115939	Sus scrofa	100.00	1.00e-73	267.00
IUUC-Tgu-117289	Taeniopygia guttata	100.00	1.00e-73	269.00
IUUC-Tsy-119103	Tarsius syrichta	100.00	1.00e-50	192.00
IUUC-Tca-121025	Theobroma cacao	52.60	1.00e-39	156.00
IUUC-Tre-121971	Trichoderma reesei	53.57	4.00e-37	146.00
IUUC-Tvi-122622	Trichoderma virens	54.29	2.00e-37	147.00
IUUC-Tae-123220	Triticum aestivum	54.48	3.00e-38	150.00
IUUC-Tur-126236	Triticum urartu	54.01	8.00e-39	152.00
IUUC-Tme-127171	Tuber melanosporum	48.18	6.00e-30	122.00
IUUC-Tbe-128105	Tupaia belangeri	96.40	1.00e-76	280.00
IUUC-Ttr-128790	Tursiops truncatus	100.00	1.00e-73	270.00
IUUC-Vda-129776	Verticillium dahliae	52.48	9.00e-37	145.00
IUUC-Vpa-130575	Vicugna pacos	99.28	2.00e-71	262.00
IUUC-Vvi-130831	Vitis vinifera	56.30	8.00e-40	155.00
IUUC-Xtr-132359	Xenopus tropicalis	93.75	2.00e-71	260.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence