iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021800

Ensembl Protein ID

ENSCPOP00000019751.1

UniProt Accession

H0W9U1; H0W9U1_CAVPO

Genbank Protein ID

ENSCPOP00000019751

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02049845

Gene Name

RAG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000004516.3	ENSCPOT00000004565.2	ENSCPOP00000019751.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	90.48	0.00e+00	1850.00	IUUC-Hsa-045964
E3 activity/RING/RING	88.33	0.00e+00	1832.00	IUUC-Mmu-064297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MDVSLPPSLG LSSAPDEIQH PHIKFSEWKF KLFRVRSLEK APGEAQKEKD SCEGKTSLEQ 60
SPVVLDKLGG QKPVLTQPAL KPHPKFSKKS LDDGKAREKA IHLANLRHFC RICGNSFKTD 120

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Nucleotide Sequence
(Fasta)

ATGGATGTCT CTTTGCCACC CAGTTTGGGA CTCAGTTCTG CCCCTGATGA AATTCAACAT 60
CCACATATTA AATTTTCAGA GTGGAAATTT AAACTATTCA GGGTGAGATC CTTGGAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002250--P:adaptive immune response
GO:0010390--P:histone monoubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0045582--P:positive regulation of T cell differentiation
GO:0002331--P:pre-B cell allelic exclusion
GO:0051865--P:protein autoubiquitination
GO:0033077--P:T cell differentiation in thymus
GO:0043029--P:T cell homeostasis
GO:0048538--P:thymus development
GO:0033151--P:V(D)J recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001206	Ailuropoda melanoleuca	90.23	0.00e+00	1902.00
IUUC-Apl-003271	Anas platyrhynchos	76.06	0.00e+00	1631.00
IUUC-Aca-004400	Anolis carolinensis	73.60	0.00e+00	1608.00
IUUC-Ame-011295	Astyanax mexicanus	58.42	0.00e+00	1211.00
IUUC-Bta-012421	Bos taurus	90.21	0.00e+00	1902.00
IUUC-Cja-019891	Callithrix jacchus	89.18	0.00e+00	1866.00
IUUC-Cfa-020740	Canis familiaris	83.43	0.00e+00	1798.00
IUUC-Csa-024203	Chlorocebus sabaeus	89.13	0.00e+00	1669.00
IUUC-Dre-028416	Danio rerio	58.81	0.00e+00	1206.00
IUUC-Dno-029101	Dasypus novemcinctus	89.21	0.00e+00	1857.00
IUUC-Eca-033385	Equus caballus	91.56	0.00e+00	1927.00
IUUC-Fca-036545	Felis catus	89.56	0.00e+00	1895.00
IUUC-Fal-037208	Ficedula albicollis	74.98	0.00e+00	1623.00
IUUC-Gmo-039622	Gadus morhua	54.87	0.00e+00	1164.00
IUUC-Gga-041182	Gallus gallus	75.51	0.00e+00	1590.00
IUUC-Gac-041682	Gasterosteus aculeatus	57.38	0.00e+00	1193.00
IUUC-Ggo-044510	Gorilla gorilla	90.33	0.00e+00	1898.00
IUUC-Hsa-045964	Homo sapiens	90.23	0.00e+00	1898.00
IUUC-Itr-048862	Ictidomys tridecemlineatus	91.00	0.00e+00	1907.00
IUUC-Lch-050041	Latimeria chalumnae	68.95	0.00e+00	1454.00
IUUC-Loc-052464	Lepisosteus oculatus	63.49	0.00e+00	1358.00
IUUC-Laf-053544	Loxodonta africana	89.08	0.00e+00	1885.00
IUUC-Mcc-054867	Macaca mulatta	90.04	0.00e+00	1893.00
IUUC-Meu-055986	Macropus eugenii	81.00	0.00e+00	1572.00
IUUC-Mga-059262	Meleagris gallopavo	75.70	0.00e+00	1603.00
IUUC-Mdo-062686	Monodelphis domestica	81.11	0.00e+00	1766.00
IUUC-Mmu-064297	Mus musculus	87.92	0.00e+00	1909.00
IUUC-Mpu-066027	Mustela putorius furo	89.94	0.00e+00	1877.00
IUUC-Mlu-067885	Myotis lucifugus	90.90	0.00e+00	1916.00
IUUC-Nle-070073	Nomascus leucogenys	89.94	0.00e+00	1894.00
IUUC-Ont-071400	Oreochromis niloticus	60.88	0.00e+00	1263.00
IUUC-Oan-072920	Ornithorhynchus anatinus	93.91	0.00e+00	781.00
IUUC-Ocu-074616	Oryctolagus cuniculus	90.60	0.00e+00	1889.00
IUUC-Ola-086828	Oryzias latipes	60.84	0.00e+00	1246.00
IUUC-Oga-088675	Otolemur garnettii	93.36	2.00e-153	534.00
IUUC-Oar-090380	Ovis aries	89.18	0.00e+00	1891.00
IUUC-Ptr-090648	Pan troglodytes	90.42	0.00e+00	1900.00
IUUC-Pan-092036	Papio anubis	89.94	0.00e+00	1890.00
IUUC-Psi-093130	Pelodiscus sinensis	79.27	0.00e+00	1718.00
IUUC-Pfo-097273	Poecilia formosa	60.80	0.00e+00	1219.00
IUUC-Pca-100134	Procavia capensis	93.01	0.00e+00	1421.00
IUUC-Rno-105632	Rattus norvegicus	88.59	0.00e+00	1916.00
IUUC-Sha-107238	Sarcophilus harrisii	80.15	0.00e+00	1754.00
IUUC-Sar-113591	Sorex araneus	76.99	0.00e+00	1590.00
IUUC-Ssc-115720	Sus scrofa	89.08	0.00e+00	1868.00
IUUC-Tgu-117030	Taeniopygia guttata	74.47	0.00e+00	1604.00
IUUC-Tru-117669	Takifugu rubripes	57.80	0.00e+00	1140.00
IUUC-Tsy-119578	Tarsius syrichta	85.34	0.00e+00	1798.00
IUUC-Tni-120073	Tetraodon nigroviridis	59.36	0.00e+00	1184.00
IUUC-Tbe-128029	Tupaia belangeri	83.48	0.00e+00	925.00
IUUC-Ttr-128677	Tursiops truncatus	91.08	0.00e+00	789.00
IUUC-Vpa-130346	Vicugna pacos	94.36	0.00e+00	877.00
IUUC-Xtr-132442	Xenopus tropicalis	86.60	8.00e-100	355.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence