iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067378

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02012804

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000001112.2	ENSMLUT00000001107.2	ENSMLUP00000001012.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-07	32.4	12	53
UBD/SH3	1.70e-30	104.8	385	439

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle ++   +vlpC+H+f++ Clq++    +++ k  rCP Cr
   Q: 12   CPVCLEKLDVTAKVLPCQHTFCKPCLQRI----SKAHKGLRCPECR 53
           ********88899****************....779*********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + + +l++y+a   deL l++G+ ++v+   +   gWlkgv+  +g+ G+fP+n+v 
   Q: 385  NMFVALHSYSAHGPDELDLQRGEGIRVL--GKYQDGWLKGVSLVTGRVGIFPNNYVI 439
           7889************************..555679*******************96 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MDDLTLLDLL ECPVCLEKLD VTAKVLPCQH TFCKPCLQRI SKAHKGLRCP ECRTLVFGSI 60
EALPANLLLV RLLDGVRSGP SSGRGGSFRR PGVLALQDGR KSRTHPRGLQ ASPFRLVPNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGATT TGACGTTACT TGATCTCCTG GAGTGCCCCG TGTGCTTGGA AAAGCTCGAT 60
GTCACAGCCA AAGTCCTCCC TTGCCAGCAC ACCTTCTGCA AACCATGTCT CCAGAGGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	86.69	0.00e+00	1106.00
IUUC-Apl-003443	Anas platyrhynchos	58.78	7.00e-170	590.00
IUUC-Aca-004632	Anolis carolinensis	53.49	6.00e-168	584.00
IUUC-Bta-013400	Bos taurus	89.06	0.00e+00	1097.00
IUUC-Cel-018180	Caenorhabditis elegans	26.73	1.00e-21	98.60
IUUC-Cja-019686	Callithrix jacchus	73.91	0.00e+00	911.00
IUUC-Cfa-020893	Canis familiaris	87.24	0.00e+00	1086.00
IUUC-Cpo-021638	Cavia porcellus	79.78	0.00e+00	1003.00
IUUC-Csa-023846	Chlorocebus sabaeus	85.58	0.00e+00	1075.00
IUUC-Cho-024609	Choloepus hoffmanni	84.47	1.00e-164	573.00
IUUC-Dno-028940	Dasypus novemcinctus	83.33	0.00e+00	1052.00
IUUC-Dor-030491	Dipodomys ordii	74.93	4.00e-124	438.00
IUUC-Dse-031414	Dothistroma septosporum	32.84	7.00e-08	53.10
IUUC-Ete-032513	Echinops telfairi	83.57	0.00e+00	1036.00
IUUC-Eca-034241	Equus caballus	88.05	0.00e+00	1129.00
IUUC-Eeu-034636	Erinaceus europaeus	78.98	0.00e+00	928.00
IUUC-Fca-035862	Felis catus	84.11	0.00e+00	1065.00
IUUC-Gga-040748	Gallus gallus	53.63	7.00e-139	487.00
IUUC-Ggo-045267	Gorilla gorilla	85.71	0.00e+00	1094.00
IUUC-Hsa-045761	Homo sapiens	85.30	0.00e+00	1085.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	82.69	0.00e+00	1042.00
IUUC-Lch-050498	Latimeria chalumnae	43.92	3.00e-121	429.00
IUUC-Laf-054061	Loxodonta africana	77.76	0.00e+00	826.00
IUUC-Mcc-054746	Macaca mulatta	84.88	0.00e+00	1048.00
IUUC-Meu-056390	Macropus eugenii	58.90	2.00e-91	330.00
IUUC-Mmr-061390	Microcebus murinus	81.51	0.00e+00	868.00
IUUC-Mdo-062951	Monodelphis domestica	71.64	0.00e+00	947.00
IUUC-Mmu-063840	Mus musculus	78.85	0.00e+00	1005.00
IUUC-Mpu-065840	Mustela putorius furo	85.87	0.00e+00	1106.00
IUUC-Nle-069535	Nomascus leucogenys	82.94	0.00e+00	1028.00
IUUC-Opr-070739	Ochotona princeps	79.67	0.00e+00	1004.00
IUUC-Oan-073468	Ornithorhynchus anatinus	66.53	0.00e+00	780.00
IUUC-Ocu-074343	Oryctolagus cuniculus	80.65	0.00e+00	986.00
IUUC-Oga-088276	Otolemur garnettii	78.85	0.00e+00	984.00
IUUC-Oar-090315	Ovis aries	88.12	0.00e+00	1096.00
IUUC-Ptr-091119	Pan troglodytes	85.03	0.00e+00	1083.00
IUUC-Pan-092158	Papio anubis	87.38	0.00e+00	803.00
IUUC-Psi-092959	Pelodiscus sinensis	60.70	0.00e+00	729.00
IUUC-Pab-097675	Pongo abelii	86.26	0.00e+00	1079.00
IUUC-Pca-101021	Procavia capensis	76.58	0.00e+00	924.00
IUUC-Pva-102619	Pteropus vampyrus	87.35	0.00e+00	1069.00
IUUC-Rno-105918	Rattus norvegicus	78.43	0.00e+00	1001.00
IUUC-Sha-107391	Sarcophilus harrisii	67.84	0.00e+00	905.00
IUUC-Sar-113148	Sorex araneus	80.92	0.00e+00	642.00
IUUC-Ssc-116219	Sus scrofa	78.47	6.00e-126	443.00
IUUC-Tgu-116584	Taeniopygia guttata	55.88	7.00e-106	377.00
IUUC-Tsy-118968	Tarsius syrichta	80.32	5.00e-159	554.00
IUUC-Tbe-128007	Tupaia belangeri	86.65	0.00e+00	801.00
IUUC-Ttr-128499	Tursiops truncatus	85.89	0.00e+00	1120.00
IUUC-Vpa-130075	Vicugna pacos	80.68	5.00e-77	281.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence