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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Ath-007058
Ensembl Protein ID AT1G62020.1
UniProt Accession Q94A40; O80706; COPA1_ARATH
Genbank Protein ID AAC28519.1; AEE33914.1; AAK91416.1; AAN46802.1
Protein Name Coatomer subunit alpha-1; Alpha-coat protein 1
Genbank Nucleotide ID AC004392; CP002684; AY050400; BT001048
Gene Name At1g62020; F8K4.21
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT1G62020 AT1G62020.1 AT1G62020.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndexPINAHINT
Post-translational Modifications (PTMs)
dbPPTdbPTM
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.20e-39 133.4 50 86
UBD/Beta-Prp 2.00e-78 264.5 3 323
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H+++v++++f ++ +l+vsG+dD +ikvW+++ +++l
   Q: 50   HEGPVRGVHFhNSqPLFVSGGDDYKIKVWNYKNHRCL 86
           9*********9777*****************999997 PP
   

   UBD/Beta-Prp
   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsls 101
           t +++++++++ + f+p++++++++  +g i++wd+++g+l+ ++ +he++v+ v f+++++++v+g++D+ ikvw++++  c+ tl gh d++++++
   Q: 3    TKFETKSNRVKGLSFHPKRPWILASLHSGVIQLWDYRMGTLIDRFDEHEGPVRGVHFHNSQPLFVSGGDDYKIKVWNYKNHRCLFTLLGHLDYIRTVQ 100
           67889999****************************************************************************************** PP
   S: 102  fspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..........................ktgkllr 173
           f+ +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                            + +++
   Q: 101  FHHEYPWIVSASDDQTIRIWNWQSRTCVS-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgalrkktvspaddimrltqmnsdlfgGVDAIVK 197
           *****************************.********************************************999999777666666663333333 PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvis 269
              +gh++ v++ +f+++ + +vsg++d++vklw + +++   v+tl+gh +nv+sv f+ +++++vs s+D+sir+Wd ++++ l+t+ +++++++ 
   Q: 198  YVLEGHDRGVNWAAFHPTLPLIVSGADDRQVKLWRMNETKAweVDTLRGHMNNVSSVMFHAKQDIIVSNSEDKSIRVWDATKRTGLQTFRREHDRFWI 295
           33555********************************887778******************************************************* PP
   S: 270  vavlsfgdnvlvlgsedskvniwklkknep 299
            av +++ n l++g  ds   ++kl++++p
   Q: 296  LAV-HPEMNLLAAG-HDSGMIVFKLERERP 323
           ***.6766655555.689999999988765 PP
   
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
Protein Sequence
(Fasta)
MLTKFETKSN RVKGLSFHPK RPWILASLHS GVIQLWDYRM GTLIDRFDEH EGPVRGVHFH 60
NSQPLFVSGG DDYKIKVWNY KNHRCLFTLL GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ath-007058|E3,WD_repeat;UBD,Beta-Prp|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTTTTTTTA AGGATATATA GAATTCATCA CTGAATACAT GTTTTTATCC CAAATTAACG 60
CAAAAGAGAG AACTCGAGAT CTGGGCATAG CGACTCACTC AGATCTATAC ACCTTCTTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-007058|E3,WD_repeat;UBD,Beta-Prp|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR024977--Apc4_WD40_dom
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12894--ANAPC4_WD40
PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0016020--C:membrane
GO:0005886--C:plasma membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER
KEGG ath:AT1G62020
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000064 Aegilops tauschii 84.28 0.00e+00 1519.00
IUUC-Aml-001758 Ailuropoda melanoleuca 54.09 0.00e+00 1351.00
IUUC-Atr-002493 Amborella trichopoda 80.85 0.00e+00 1999.00
IUUC-Apl-003385 Anas platyrhynchos 49.40 0.00e+00 1041.00
IUUC-Aca-005154 Anolis carolinensis 79.41 2.00e-96 344.00
IUUC-Aly-006020 Arabidopsis lyrata 98.03 0.00e+00 2344.00
IUUC-Ago-007992 Ashbya gossypii 42.86 0.00e+00 963.00
IUUC-Ame-011229 Astyanax mexicanus 53.32 0.00e+00 1321.00
IUUC-Bgr-012300 Blumeria graminis 46.91 0.00e+00 1078.00
IUUC-Bta-012524 Bos taurus 54.57 0.00e+00 1344.00
IUUC-Bdi-014549 Brachypodium distachyon 77.72 0.00e+00 2005.00
IUUC-Cel-018115 Caenorhabditis elegans 54.64 0.00e+00 944.00
IUUC-Cja-019107 Callithrix jacchus 53.78 0.00e+00 1331.00
IUUC-Cfa-020675 Canis familiaris 53.75 0.00e+00 1323.00
IUUC-Cpo-021813 Cavia porcellus 54.57 0.00e+00 1362.00
IUUC-Cre-022969 Chlamydomonas reinhardtii 71.38 0.00e+00 1268.00
IUUC-Csa-023523 Chlorocebus sabaeus 54.57 0.00e+00 1362.00
IUUC-Cho-024704 Choloepus hoffmanni 41.95 8.00e-172 597.00
IUUC-Cin-025572 Ciona intestinalis 50.36 0.00e+00 1239.00
IUUC-Cme-027222 Cyanidioschyzon merolae 42.81 1.00e-145 511.00
IUUC-Dre-027421 Danio rerio 53.68 0.00e+00 1334.00
IUUC-Dno-029303 Dasypus novemcinctus 54.69 0.00e+00 1367.00
IUUC-Dor-030290 Dipodomys ordii 52.90 8.00e-165 574.00
IUUC-Dse-031543 Dothistroma septosporum 45.93 0.00e+00 1069.00
IUUC-Ete-032873 Echinops telfairi 59.74 0.00e+00 1045.00
IUUC-Eca-033773 Equus caballus 53.69 0.00e+00 1324.00
IUUC-Eeu-034874 Erinaceus europaeus 40.66 0.00e+00 650.00
IUUC-Fca-035739 Felis catus 53.46 0.00e+00 1316.00
IUUC-Fal-037263 Ficedula albicollis 51.18 0.00e+00 1206.00
IUUC-Gmo-039602 Gadus morhua 50.32 0.00e+00 1235.00
IUUC-Gga-040590 Gallus gallus 54.73 0.00e+00 1365.00
IUUC-Gac-041318 Gasterosteus aculeatus 53.90 0.00e+00 1350.00
IUUC-Ggo-045029 Gorilla gorilla 54.17 0.00e+00 1353.00
IUUC-Hsa-046078 Homo sapiens 54.17 0.00e+00 1353.00
IUUC-Hvu-047556 Hordeum vulgare 77.97 0.00e+00 2009.00
IUUC-Itr-048881 Ictidomys tridecemlineatus 45.53 0.00e+00 753.00
IUUC-Kpa-049256 Komagataella pastoris 44.87 0.00e+00 1064.00
IUUC-Lch-049706 Latimeria chalumnae 54.52 0.00e+00 1348.00
IUUC-Lpe-051316 Leersia perrieri 85.01 0.00e+00 1532.00
IUUC-Laf-053510 Loxodonta africana 55.18 0.00e+00 1389.00
IUUC-Mcc-055836 Macaca mulatta 54.50 0.00e+00 1347.00
IUUC-Meu-056238 Macropus eugenii 56.72 0.00e+00 773.00
IUUC-Mpo-057300 Magnaporthe poae 46.40 0.00e+00 1102.00
IUUC-Mla-059019 Melampsora laricipopulina 57.48 0.00e+00 1053.00
IUUC-Mga-059499 Meleagris gallopavo 54.64 0.00e+00 1362.00
IUUC-Mmr-061102 Microcebus murinus 54.01 0.00e+00 1338.00
IUUC-Mdo-062594 Monodelphis domestica 54.77 0.00e+00 1382.00
IUUC-Mmu-063736 Mus musculus 54.12 0.00e+00 1350.00
IUUC-Mac-065398 Musa acuminata 72.04 0.00e+00 1832.00
IUUC-Mpu-066701 Mustela putorius furo 54.61 0.00e+00 1364.00
IUUC-Mlu-067392 Myotis lucifugus 54.89 0.00e+00 1362.00
IUUC-Nle-069634 Nomascus leucogenys 66.07 0.00e+00 946.00
IUUC-Opr-070952 Ochotona princeps 41.45 0.00e+00 655.00
IUUC-Ont-072488 Oreochromis niloticus 53.80 0.00e+00 1330.00
IUUC-Ocu-074211 Oryctolagus cuniculus 54.65 0.00e+00 1360.00
IUUC-Oba-075761 Oryza barthii 84.76 0.00e+00 1530.00
IUUC-Obr-076429 Oryza brachyantha 78.13 0.00e+00 2003.00
IUUC-Ogl-077364 Oryza glaberrima 84.76 0.00e+00 1530.00
IUUC-Ogu-078257 Oryza glumaepatula 84.64 0.00e+00 1528.00
IUUC-Oin-079274 Oryza indica 84.64 0.00e+00 1529.00
IUUC-Olo-080466 Oryza longistaminata 84.94 0.00e+00 1514.00
IUUC-Ome-081993 Oryza meridionalis 84.08 0.00e+00 1387.00
IUUC-Oni-082874 Oryza nivara 84.64 0.00e+00 1527.00
IUUC-Opu-083885 Oryza punctata 84.52 0.00e+00 1523.00
IUUC-Oru-084274 Oryza rufipogon 84.64 0.00e+00 1528.00
IUUC-Osa-085565 Oryza sativa 84.64 0.00e+00 1528.00
IUUC-Ola-086921 Oryzias latipes 53.46 0.00e+00 1316.00
IUUC-Olu-087639 Ostreococcus lucimarinus 62.76 0.00e+00 1565.00
IUUC-Oga-087991 Otolemur garnettii 51.29 0.00e+00 1260.00
IUUC-Oar-089590 Ovis aries 54.41 0.00e+00 1359.00
IUUC-Ptr-090808 Pan troglodytes 54.25 0.00e+00 1355.00
IUUC-Pan-092475 Papio anubis 54.44 0.00e+00 1356.00
IUUC-Psi-093044 Pelodiscus sinensis 48.36 0.00e+00 984.00
IUUC-Ppa-095254 Physcomitrella patens 70.02 0.00e+00 1778.00
IUUC-Pab-098497 Pongo abelii 54.57 0.00e+00 1364.00
IUUC-Pop-099992 Populus trichocarpa 84.99 0.00e+00 2099.00
IUUC-Pca-100413 Procavia capensis 60.61 0.00e+00 694.00
IUUC-Pva-102126 Pteropus vampyrus 52.17 0.00e+00 1282.00
IUUC-Pyt-104778 Pyrenophora triticirepentis 44.83 1.00e-172 599.00
IUUC-Rno-105428 Rattus norvegicus 54.24 0.00e+00 1356.00
IUUC-Sce-106464 Saccharomyces cerevisiae 42.31 0.00e+00 949.00
IUUC-Sha-107301 Sarcophilus harrisii 53.80 0.00e+00 1339.00
IUUC-Sja-107961 Schizosaccharomyces japonicus 44.70 0.00e+00 1070.00
IUUC-Spo-108217 Schizosaccharomyces pombe 43.83 0.00e+00 1049.00
IUUC-Smo-108819 Selaginella moellendorffii 67.21 0.00e+00 1725.00
IUUC-Sit-109697 Setaria italica 85.13 0.00e+00 1534.00
IUUC-Sly-111759 Solanum lycopersicum 82.77 0.00e+00 2121.00
IUUC-Stu-112564 Solanum tuberosum 82.53 0.00e+00 2113.00
IUUC-Sar-113313 Sorex araneus 44.17 5.00e-173 600.00
IUUC-Sbi-114388 Sorghum bicolor 77.05 0.00e+00 1983.00
IUUC-Ssc-115933 Sus scrofa 54.57 0.00e+00 1360.00
IUUC-Tgu-117109 Taeniopygia guttata 43.27 6.00e-108 383.00
IUUC-Tru-117772 Takifugu rubripes 52.97 0.00e+00 1301.00
IUUC-Tsy-119105 Tarsius syrichta 52.43 0.00e+00 1048.00
IUUC-Tni-120556 Tetraodon nigroviridis 41.32 0.00e+00 877.00
IUUC-Tae-123611 Triticum aestivum 84.28 0.00e+00 1519.00
IUUC-Tur-126754 Triticum urartu 76.15 0.00e+00 1935.00
IUUC-Tbe-127882 Tupaia belangeri 69.35 2.00e-129 456.00
IUUC-Ttr-128217 Tursiops truncatus 52.25 0.00e+00 1283.00
IUUC-Vpa-130537 Vicugna pacos 54.38 0.00e+00 1332.00
IUUC-Vvi-130958 Vitis vinifera 81.79 0.00e+00 2097.00
IUUC-Xtr-132857 Xenopus tropicalis 52.85 0.00e+00 1279.00
Created Date 25-Jun-2017

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