iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054108

UUCD1 version

UUC-LoA-00581

Ensembl Protein ID

ENSLAFP00000014126.2

UniProt Accession

G3THQ5; G3THQ5_LOXAF

Protein Name

Uncharacterized protein

Gene Name

BMI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000016845.2	ENSLAFT00000016844.2	ENSLAFP00000014126.2
ENSLAFG00000016845.2	ENSLAFT00000035707.1	ENSLAFP00000022626.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.20e-06	26.6	18	57
ULD/UDP/UFD/RAWUL	3.60e-30	104.7	131	230

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +C   f d + +  C H f+++C+ ++        ++ +CP+C+
   Q: 18   CVLCGGYFIDATTIIECLHSFCKTCIVHY------LETSKYCPICD 57
           ********99999****************......**********5 PP

ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsk..............lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiw 75
           isls+e++++n+ +++ +              ++k+ylrc+a++tV+hl+kfl++k+++++++++d+++e+e+L+d++tL++i+yi++w
   Q: 131  ISLSIEFFDQNRLDRKVNkdkekskeemhpqaNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTW 219
           78999999999988877788889999*************************************************************** PP
   S: 76   kkegpLvLqYr 86
           +++gpL+L+Yr
   Q: 220  RRNGPLPLKYR 230
           **********9 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVHYLETS KYCPICDVQV 60
HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADAANGS NEDRGEVADE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCATCGAA CAACAAGAAT CAAAATCACT GAACTAAATC CCCACCTAAT GTGTGTGCTT 60
TGTGGAGGGT ACTTCATTGA TGCCACAACC ATAATAGAAT GTCTACATTC CTGTAAGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0000792--C:heterochromatin
GO:0016604--C:nuclear body
GO:0031519--C:PcG protein complex
GO:0000151--C:ubiquitin ligase complex
GO:1990841--F:promoter-specific chromatin binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0008270--F:zinc ion binding
GO:0007420--P:brain development
GO:0006306--P:DNA methylation
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0016574--P:histone ubiquitination
GO:0006959--P:humoral immune response
GO:0001701--P:in utero embryonic development
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030890--P:positive regulation of B cell proliferation
GO:0033092--P:positive regulation of immature T cell proliferation in thymus
GO:2000011--P:regulation of adaxial/abaxial pattern formation
GO:0021903--P:rostrocaudal neural tube patterning
GO:0048103--P:somatic stem cell division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001498	Ailuropoda melanoleuca	96.67	8.00e-168	582.00
IUUC-Apl-004208	Anas platyrhynchos	92.81	3.00e-133	467.00
IUUC-Aca-004661	Anolis carolinensis	82.73	9.00e-139	486.00
IUUC-Aly-006155	Arabidopsis lyrata	40.00	5.00e-12	65.90
IUUC-Ath-007649	Arabidopsis thaliana	42.50	1.00e-12	67.40
IUUC-Ame-010610	Astyanax mexicanus	71.26	2.00e-137	481.00
IUUC-Bta-012606	Bos taurus	96.97	8.00e-169	585.00
IUUC-Cja-019482	Callithrix jacchus	97.48	1.00e-178	618.00
IUUC-Cfa-020482	Canis familiaris	96.67	8.00e-168	582.00
IUUC-Cpo-022061	Cavia porcellus	97.48	9.00e-179	619.00
IUUC-Csa-024102	Chlorocebus sabaeus	97.80	4.00e-180	624.00
IUUC-Cho-025081	Choloepus hoffmanni	79.84	6.00e-110	389.00
IUUC-Cin-025612	Ciona intestinalis	48.37	2.00e-51	196.00
IUUC-Dre-027929	Danio rerio	77.27	1.00e-139	489.00
IUUC-Dno-029797	Dasypus novemcinctus	95.91	0.00e+00	633.00
IUUC-Dor-030256	Dipodomys ordii	94.85	6.00e-168	582.00
IUUC-Dme-031904	Drosophila melanogaster	43.83	1.00e-52	202.00
IUUC-Ete-033148	Echinops telfairi	62.81	3.00e-81	294.00
IUUC-Eca-033318	Equus caballus	97.27	4.00e-169	587.00
IUUC-Eeu-034547	Erinaceus europaeus	84.28	1.00e-147	515.00
IUUC-Fca-035866	Felis catus	97.27	9.00e-169	585.00
IUUC-Fal-036660	Ficedula albicollis	93.94	2.00e-158	551.00
IUUC-Gmo-039341	Gadus morhua	81.82	1.00e-125	442.00
IUUC-Gga-040611	Gallus gallus	93.40	1.00e-163	568.00
IUUC-Gac-041888	Gasterosteus aculeatus	71.55	8.00e-128	449.00
IUUC-Gma-042798	Glycine max	39.02	5.00e-12	65.50
IUUC-Ggo-045027	Gorilla gorilla	97.80	3.00e-179	620.00
IUUC-Hsa-045665	Homo sapiens	97.88	7.00e-180	623.00
IUUC-Itr-049045	Ictidomys tridecemlineatus	97.17	1.00e-177	615.00
IUUC-Lch-049714	Latimeria chalumnae	84.29	1.00e-161	561.00
IUUC-Lpe-051490	Leersia perrieri	42.03	9.00e-12	64.70
IUUC-Loc-052161	Lepisosteus oculatus	80.06	8.00e-142	496.00
IUUC-Mcc-055562	Macaca mulatta	97.88	5.00e-180	623.00
IUUC-Meu-056709	Macropus eugenii	95.76	2.00e-171	594.00
IUUC-Mga-060104	Meleagris gallopavo	90.51	2.00e-118	417.00
IUUC-Mmr-061191	Microcebus murinus	97.88	4.00e-180	624.00
IUUC-Mdo-062711	Monodelphis domestica	91.13	4.00e-151	526.00
IUUC-Mmu-064255	Mus musculus	94.03	5.00e-166	576.00
IUUC-Mpu-066466	Mustela putorius furo	96.36	1.00e-167	582.00
IUUC-Mlu-067622	Myotis lucifugus	97.17	5.00e-178	616.00
IUUC-Nle-069253	Nomascus leucogenys	97.80	3.00e-180	624.00
IUUC-Opr-070511	Ochotona princeps	96.86	5.00e-177	613.00
IUUC-Ont-072177	Oreochromis niloticus	82.20	2.00e-127	448.00
IUUC-Oan-073336	Ornithorhynchus anatinus	95.45	5.00e-169	586.00
IUUC-Ocu-074113	Oryctolagus cuniculus	96.86	1.00e-168	585.00
IUUC-Oba-075690	Oryza barthii	42.25	5.00e-12	65.50
IUUC-Ogl-077513	Oryza glaberrima	42.25	6.00e-12	65.50
IUUC-Ogu-078755	Oryza glumaepatula	42.25	7.00e-12	65.50
IUUC-Oni-082398	Oryza nivara	42.25	7.00e-12	65.50
IUUC-Oru-084965	Oryza rufipogon	42.25	6.00e-12	65.50
IUUC-Osa-086282	Oryza sativa	42.25	4.00e-12	65.90
IUUC-Ola-087057	Oryzias latipes	83.40	5.00e-122	430.00
IUUC-Oga-088346	Otolemur garnettii	97.80	3.00e-179	620.00
IUUC-Oar-089843	Ovis aries	96.97	8.00e-169	585.00
IUUC-Ptr-090486	Pan troglodytes	97.80	3.00e-179	620.00
IUUC-Pan-092667	Papio anubis	97.03	1.00e-157	548.00
IUUC-Psi-093469	Pelodiscus sinensis	93.33	1.00e-170	591.00
IUUC-Pma-094481	Petromyzon marinus	72.17	8.00e-89	319.00
IUUC-Pfo-097156	Poecilia formosa	78.33	5.00e-131	460.00
IUUC-Pab-097670	Pongo abelii	97.80	3.00e-179	620.00
IUUC-Pop-098807	Populus trichocarpa	37.65	2.00e-12	66.60
IUUC-Pva-102800	Pteropus vampyrus	97.80	3.00e-179	620.00
IUUC-Rno-105128	Rattus norvegicus	92.45	2.00e-167	581.00
IUUC-Sha-106747	Sarcophilus harrisii	95.45	4.00e-161	560.00
IUUC-Sar-113416	Sorex araneus	97.17	5.00e-178	616.00
IUUC-Ssc-115864	Sus scrofa	97.48	4.00e-179	620.00
IUUC-Tgu-116851	Taeniopygia guttata	92.81	6.00e-134	469.00
IUUC-Tru-117698	Takifugu rubripes	84.34	6.00e-123	433.00
IUUC-Tsy-119590	Tarsius syrichta	97.17	3.00e-178	617.00
IUUC-Tni-120170	Tetraodon nigroviridis	83.33	9.00e-128	449.00
IUUC-Tbe-127790	Tupaia belangeri	97.48	9.00e-179	619.00
IUUC-Ttr-129316	Tursiops truncatus	97.27	4.00e-177	613.00
IUUC-Vpa-130669	Vicugna pacos	97.58	2.00e-169	588.00
IUUC-Xtr-131912	Xenopus tropicalis	83.69	7.00e-146	509.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence