iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003903

Ensembl Protein ID

ENSAPLP00000015714.1

UniProt Accession

U3J886; U3J886_ANAPL

Genbank Protein ID

ENSAPLP00000015714

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01082403

Gene Name

WSB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000015816.1	ENSAPLT00000016515.1	ENSAPLP00000015714.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.70e-14	51.2	374	419
E3 adaptor/Cullin RING/DCX/DWD	3.90e-32	108.6	168	202
UBD/Beta-Prp	4.50e-46	157.1	133	378

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
           +++w +++++ SLqhLCR+aIrr +++ ++   + LP+P++  ++L y+
   Q: 374  VYFWATPRQVSSLQHLCRMAIRRVMPTSQV---KNLPIPSKVVEFLCYQ 419
           689************************777...*************987 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Ht+ v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 168  HTEVVRDLTFaPDgsLILVSASRDKTLRVWDLKDD 202
           9**********8865668*************9987 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsf 102
            kf +d+ llatg  +g+ik+wdv tgkll  l +h++ v++++f pdg+ ilv++s+D+t++vwdl+ +g ++ +l+gh++ v+ ++f
   Q: 133  FKFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLMDHTEVVRDLTFAPDGSlILVSASRDKTLRVWDLKdDGNMMKVLRGHQNWVYGCAF 221
           68899999***********************************************************9799****************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tggh 179
           sp+++ l s ++ + + +wd+++++ ++  l+gh+  v   +++pdg ll+++s+D+ v +Wd   g +l ++             g++
   Q: 222  SPDSSILCSVGASKAVFLWDMDKYSMIR-KLEGHHNDVVACEFSPDGALLATASYDTRVYVWDPYIGVILMDFghlfppptpifaGGAN 309
           ****************************.999999999999*******************************************9888* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
           ++ v+s+sf+++g +++s ++d+ v++w + ++     + +  +n ++  fs ++  l+ g++Dgs+++W 
   Q: 310  DRWVRSVSFSHDGLHIASLADDKMVRFWRIDEE--YPVQVAPLNNGLCCTFSTDGSVLAAGTQDGSVYFWA 378
           ******************************998..68899******************************2 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

VSYWNFLSVF LPARSRTVGE LLAPTSPFDK KCGRENWTVA FAPDGSYFAW SQGHRIVKLV 60
PWSQCLNNFL LHGTKNVANS ISTRLPRQNS DSGQKNKPCE HIIDCGDIVW SLAFGSSVPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTCTTACT GGAATTTCCT CTCTGTTTTC CTTCCAGCAC GGTCCCGTAC TGTAGGAGAG 60
CTCTTAGCCC CCACTTCTCC TTTTGACAAG AAGTGTGGCC GTGAGAACTG GACTGTCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	90.66	0.00e+00	761.00
IUUC-Aca-005214	Anolis carolinensis	78.55	0.00e+00	688.00
IUUC-Ame-011740	Astyanax mexicanus	75.25	0.00e+00	657.00
IUUC-Bta-013475	Bos taurus	89.93	0.00e+00	760.00
IUUC-Cja-019053	Callithrix jacchus	90.64	0.00e+00	778.00
IUUC-Cfa-020103	Canis familiaris	90.42	0.00e+00	758.00
IUUC-Cpo-022438	Cavia porcellus	90.17	0.00e+00	776.00
IUUC-Csa-024062	Chlorocebus sabaeus	90.66	0.00e+00	781.00
IUUC-Cho-024334	Choloepus hoffmanni	78.87	0.00e+00	640.00
IUUC-Cin-025590	Ciona intestinalis	40.70	1.00e-80	293.00
IUUC-Csv-026023	Ciona savignyi	40.24	7.00e-79	287.00
IUUC-Dre-028089	Danio rerio	75.25	0.00e+00	660.00
IUUC-Dno-029436	Dasypus novemcinctus	85.40	0.00e+00	635.00
IUUC-Dor-031107	Dipodomys ordii	83.54	0.00e+00	681.00
IUUC-Ete-032326	Echinops telfairi	88.21	0.00e+00	745.00
IUUC-Eca-033401	Equus caballus	90.42	0.00e+00	760.00
IUUC-Eeu-034520	Erinaceus europaeus	87.71	0.00e+00	762.00
IUUC-Fca-036386	Felis catus	89.68	0.00e+00	756.00
IUUC-Fal-036616	Ficedula albicollis	92.91	0.00e+00	803.00
IUUC-Gmo-039335	Gadus morhua	72.97	2.00e-180	624.00
IUUC-Gga-040856	Gallus gallus	96.59	0.00e+00	827.00
IUUC-Gac-042140	Gasterosteus aculeatus	73.61	0.00e+00	645.00
IUUC-Ggo-044619	Gorilla gorilla	90.17	0.00e+00	778.00
IUUC-Hsa-046300	Homo sapiens	90.42	0.00e+00	778.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	90.42	0.00e+00	779.00
IUUC-Lch-049550	Latimeria chalumnae	81.79	8.00e-172	595.00
IUUC-Loc-051769	Lepisosteus oculatus	75.24	0.00e+00	667.00
IUUC-Laf-054576	Loxodonta africana	89.93	0.00e+00	756.00
IUUC-Mcc-054666	Macaca mulatta	89.69	6.00e-143	499.00
IUUC-Meu-055989	Macropus eugenii	87.43	0.00e+00	637.00
IUUC-Mga-059722	Meleagris gallopavo	97.30	0.00e+00	834.00
IUUC-Mmr-060970	Microcebus murinus	90.66	0.00e+00	757.00
IUUC-Mdo-062249	Monodelphis domestica	76.34	4.00e-177	613.00
IUUC-Mmu-063742	Mus musculus	85.47	0.00e+00	739.00
IUUC-Mpu-066518	Mustela putorius furo	89.68	0.00e+00	777.00
IUUC-Mlu-068063	Myotis lucifugus	89.68	0.00e+00	748.00
IUUC-Nle-069561	Nomascus leucogenys	90.42	0.00e+00	780.00
IUUC-Opr-071158	Ochotona princeps	87.68	0.00e+00	751.00
IUUC-Ont-072542	Oreochromis niloticus	72.88	0.00e+00	638.00
IUUC-Oan-073217	Ornithorhynchus anatinus	91.15	0.00e+00	776.00
IUUC-Ocu-074251	Oryctolagus cuniculus	88.73	0.00e+00	766.00
IUUC-Ola-086549	Oryzias latipes	71.91	0.00e+00	637.00
IUUC-Oga-088382	Otolemur garnettii	90.91	0.00e+00	768.00
IUUC-Oar-090263	Ovis aries	87.96	0.00e+00	757.00
IUUC-Ptr-090922	Pan troglodytes	90.66	0.00e+00	782.00
IUUC-Pan-092518	Papio anubis	90.66	0.00e+00	781.00
IUUC-Psi-093512	Pelodiscus sinensis	93.66	0.00e+00	809.00
IUUC-Pma-094324	Petromyzon marinus	58.00	2.00e-132	465.00
IUUC-Pfo-096264	Poecilia formosa	73.30	0.00e+00	642.00
IUUC-Pab-098018	Pongo abelii	88.70	0.00e+00	763.00
IUUC-Pca-101034	Procavia capensis	88.45	0.00e+00	726.00
IUUC-Pva-102862	Pteropus vampyrus	86.63	0.00e+00	694.00
IUUC-Rno-106116	Rattus norvegicus	86.73	0.00e+00	751.00
IUUC-Sha-106952	Sarcophilus harrisii	86.99	0.00e+00	744.00
IUUC-Sar-113211	Sorex araneus	80.19	6.00e-145	506.00
IUUC-Ssc-116440	Sus scrofa	90.66	0.00e+00	761.00
IUUC-Tgu-116675	Taeniopygia guttata	94.61	0.00e+00	806.00
IUUC-Tru-118295	Takifugu rubripes	71.84	1.00e-178	618.00
IUUC-Tsy-118916	Tarsius syrichta	78.62	0.00e+00	637.00
IUUC-Tni-120302	Tetraodon nigroviridis	70.87	7.00e-176	609.00
IUUC-Tbe-127416	Tupaia belangeri	78.38	0.00e+00	634.00
IUUC-Ttr-128185	Tursiops truncatus	90.17	0.00e+00	759.00
IUUC-Xtr-132465	Xenopus tropicalis	83.53	0.00e+00	736.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence