iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026006

UUCD1 version

UUC-CiS-00482

Ensembl Protein ID

ENSCSAVP00000008061.1

UniProt Accession

H2YRV1; H2YRV1_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000004801.1	ENSCSAVT00000008168.1	ENSCSAVP00000008061.1
ENSCSAVG00000004801.1	ENSCSAVT00000008169.1	ENSCSAVP00000008062.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.00e-60	203.2	92	408
ULD/UDP/UBQ/UBQ_Other	3.10e-10	39.8	918	974

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +GlkNlg+tCY+N  LQ  ++  ++r++l +    + ++e+    +++l+ +lq +f  l ++ +k+v+p+e++k+l+ +        
   Q: 92   VGLKNLGATCYVNTYLQLWYHNVSFRNALYS---LEYKDED-LALQQSLCGQLQLIFGLLESGVSKSVDPTEFIKCLGLATD-----L 170
           6******************************...4444443.68899*******************************5555.....6 PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           qqDaqEf + +l+ le++                              + +++i+d F g+++  ++c++c++ ++r ++f++l l++
   Q: 171  QQDAQEFSKLFLSLLETTP-----------------------------SLSQVIKDQFCGEYTYVTICQSCKSATQRPSNFYELDLNI 229
           **************99988.............................7899************************************ PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
           +g++     +l++cL +f +ee+l gen+yyc+kck+kq+a +k+ lkklP++L l+L Rf ++++ +sr+ki+++++fp+ Ld   +
   Q: 230  QGNK-----DLKSCLTEFLREEKLVGENQYYCTKCKSKQNAIRKICLKKLPQTLNLQLLRFVYDRASQSRQKISTNLSFPDYLDFPMV 312
           ****.....9***************************************************************************977 PP
   S: 265  ctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdD...............skVtevkeeevleetg........ 327
            +      +++++Y+L+av++H G s+ssGH+va++ + e+g+W++f+D               +                       
   Q: 313  ESGGHLLGHDDTQYKLTAVLIHRGlSASSGHFVAHIWEpESGNWYKFNDeldldsykgednvckE-------------IIqelepapk 387
           7777777778**************************9945555******6555555555444432.............2244445555 PP
   S: 328  ...........staYvlfYkr 337
                      ++ Y+l+Y +
   Q: 388  kiklskgchssKDVYMLVYSK 408
           556666689999999999976 PP

ULD/UDP/UBQ/UBQ_Other

   S: 20   sd.tVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           s+ t ++LK +i  ++++pp +q+L++ Gk L  d  tL  +++ +g+ti ++e+++
   Q: 918  STlTLKDLKIRIMNQFSVPPFDQNLWMNGKRLmNDELTLETLHIIPGCTITVVEDTP 974
           4559****************************9********************9986 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

KNSSKSNEPL IWQWVEDIDP SKITDVEVRT AYRLNLPKCK SCRKNCQGKP TCLFGLGEAQ 60
WMSAPSDLDR DNLQQKLEKQ IEAEKRKEGE LVGLKNLGAT CYVNTYLQLW YHNVSFRNAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGAATTCAA GCAAATCAAA TGAGCCATTA ATATGGCAGT GGGTGGAGGA TATTGATCCT 60
TCCAAGATCA CTGATGTAGA AGTGAGGACT GCATATCGAT TAAACCTCCC AAAATGCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00240--ubiquitin
PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	25.41	2.00e-56	212.00
IUUC-Aml-001357	Ailuropoda melanoleuca	36.36	1.00e-168	585.00
IUUC-Atr-002976	Amborella trichopoda	25.44	7.00e-69	254.00
IUUC-Apl-003773	Anas platyrhynchos	36.40	3.00e-151	527.00
IUUC-Aca-004466	Anolis carolinensis	39.89	1.00e-102	364.00
IUUC-Aly-006249	Arabidopsis lyrata	23.73	8.00e-55	207.00
IUUC-Ath-006700	Arabidopsis thaliana	23.92	4.00e-66	245.00
IUUC-Ame-011554	Astyanax mexicanus	36.50	2.00e-157	548.00
IUUC-Bta-012573	Bos taurus	36.36	4.00e-168	583.00
IUUC-Bdi-014149	Brachypodium distachyon	26.04	2.00e-61	229.00
IUUC-Bol-016289	Brassica oleracea	24.70	7.00e-66	244.00
IUUC-Bra-017205	Brassica rapa	24.84	1.00e-59	223.00
IUUC-Cel-018662	Caenorhabditis elegans	29.58	2.00e-27	116.00
IUUC-Cja-019991	Callithrix jacchus	36.65	4.00e-168	583.00
IUUC-Cfa-020294	Canis familiaris	36.68	1.00e-172	598.00
IUUC-Cpo-021706	Cavia porcellus	36.22	4.00e-160	556.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	35.40	3.00e-32	134.00
IUUC-Csa-023931	Chlorocebus sabaeus	36.64	2.00e-170	591.00
IUUC-Cho-024566	Choloepus hoffmanni	34.15	6.00e-31	128.00
IUUC-Cin-025307	Ciona intestinalis	85.71	1.00e-150	523.00
IUUC-Cne-027065	Cryptococcus neoformans	26.91	3.00e-55	208.00
IUUC-Dre-027624	Danio rerio	35.60	1.00e-174	605.00
IUUC-Dno-029633	Dasypus novemcinctus	38.18	6.00e-114	403.00
IUUC-Dor-030809	Dipodomys ordii	44.79	3.00e-79	288.00
IUUC-Ete-032818	Echinops telfairi	39.23	3.00e-92	331.00
IUUC-Eca-033692	Equus caballus	36.49	3.00e-170	590.00
IUUC-Eeu-035185	Erinaceus europaeus	38.89	1.00e-53	203.00
IUUC-Fca-035676	Felis catus	36.79	1.00e-172	598.00
IUUC-Fal-036913	Ficedula albicollis	36.44	4.00e-171	593.00
IUUC-Gmo-038532	Gadus morhua	35.05	1.00e-170	592.00
IUUC-Gga-041041	Gallus gallus	36.22	7.00e-172	596.00
IUUC-Gac-042570	Gasterosteus aculeatus	35.71	8.00e-174	602.00
IUUC-Gma-044136	Glycine max	23.91	2.00e-61	229.00
IUUC-Ggo-045367	Gorilla gorilla	35.67	4.00e-159	553.00
IUUC-Hsa-046019	Homo sapiens	36.56	2.00e-170	591.00
IUUC-Hvu-047303	Hordeum vulgare	32.30	1.00e-48	186.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	36.70	9.00e-172	595.00
IUUC-Lch-049989	Latimeria chalumnae	34.57	1.00e-172	598.00
IUUC-Lpe-051612	Leersia perrieri	25.41	4.00e-57	214.00
IUUC-Loc-052756	Lepisosteus oculatus	35.56	3.00e-174	604.00
IUUC-Laf-054043	Loxodonta africana	36.29	2.00e-170	591.00
IUUC-Mcc-054986	Macaca mulatta	36.62	1.00e-167	582.00
IUUC-Meu-056228	Macropus eugenii	45.09	6.00e-84	304.00
IUUC-Mtr-058610	Medicago truncatula	24.44	2.00e-55	209.00
IUUC-Mga-059896	Meleagris gallopavo	36.40	4.00e-163	567.00
IUUC-Mvi-060269	Microbotryum violaceum	35.52	8.00e-56	211.00
IUUC-Mmr-060887	Microcebus murinus	36.53	6.00e-170	590.00
IUUC-Mdo-062506	Monodelphis domestica	36.44	5.00e-171	593.00
IUUC-Mmu-063642	Mus musculus	36.56	1.00e-170	592.00
IUUC-Mac-064896	Musa acuminata	24.52	2.00e-56	213.00
IUUC-Mpu-066194	Mustela putorius furo	36.49	1.00e-170	592.00
IUUC-Mlu-067233	Myotis lucifugus	36.05	6.00e-168	583.00
IUUC-Nle-069052	Nomascus leucogenys	36.52	6.00e-168	583.00
IUUC-Opr-070890	Ochotona princeps	38.97	3.00e-116	411.00
IUUC-Ont-071450	Oreochromis niloticus	35.86	5.00e-173	600.00
IUUC-Oan-073252	Ornithorhynchus anatinus	32.03	9.00e-63	233.00
IUUC-Ocu-073796	Oryctolagus cuniculus	36.99	2.00e-145	508.00
IUUC-Oba-075563	Oryza barthii	25.80	4.00e-61	228.00
IUUC-Obr-076394	Oryza brachyantha	25.58	1.00e-60	226.00
IUUC-Ogl-077339	Oryza glaberrima	36.17	9.00e-36	142.00
IUUC-Ogu-079007	Oryza glumaepatula	25.53	2.00e-57	216.00
IUUC-Oin-079997	Oryza indica	25.80	3.00e-61	229.00
IUUC-Olo-080364	Oryza longistaminata	25.80	2.00e-61	229.00
IUUC-Ome-081165	Oryza meridionalis	25.34	8.00e-56	210.00
IUUC-Oni-083026	Oryza nivara	25.80	3.00e-61	228.00
IUUC-Opu-083284	Oryza punctata	25.39	2.00e-57	215.00
IUUC-Oru-084797	Oryza rufipogon	25.80	2.00e-61	229.00
IUUC-Osa-086221	Oryza sativa	36.17	9.00e-36	142.00
IUUC-Ola-086568	Oryzias latipes	35.50	3.00e-175	607.00
IUUC-Oga-088687	Otolemur garnettii	36.51	2.00e-167	581.00
IUUC-Oar-090345	Ovis aries	36.61	4.00e-160	556.00
IUUC-Ptr-090734	Pan troglodytes	36.64	3.00e-170	591.00
IUUC-Pan-091704	Papio anubis	35.74	1.00e-160	558.00
IUUC-Psi-092937	Pelodiscus sinensis	35.28	4.00e-138	483.00
IUUC-Ppa-095808	Physcomitrella patens	23.79	4.00e-47	182.00
IUUC-Pab-098129	Pongo abelii	36.56	3.00e-170	590.00
IUUC-Pop-099494	Populus trichocarpa	25.25	1.00e-61	230.00
IUUC-Pca-100647	Procavia capensis	44.86	4.00e-79	288.00
IUUC-Ppe-102091	Prunus persica	25.00	6.00e-58	218.00
IUUC-Pva-102719	Pteropus vampyrus	36.44	2.00e-170	591.00
IUUC-Rno-105363	Rattus norvegicus	36.67	2.00e-171	594.00
IUUC-Sha-107620	Sarcophilus harrisii	35.37	2.00e-154	538.00
IUUC-Smo-109487	Selaginella moellendorffii	27.01	1.00e-70	259.00
IUUC-Sit-110683	Setaria italica	25.55	2.00e-61	229.00
IUUC-Sly-111377	Solanum lycopersicum	37.05	7.00e-51	194.00
IUUC-Stu-111969	Solanum tuberosum	36.97	7.00e-55	206.00
IUUC-Sar-113099	Sorex araneus	36.64	7.00e-146	509.00
IUUC-Sbi-113833	Sorghum bicolor	40.07	4.00e-45	173.00
IUUC-Ssc-115279	Sus scrofa	30.06	1.00e-71	263.00
IUUC-Tgu-117519	Taeniopygia guttata	35.60	2.00e-153	534.00
IUUC-Tru-117651	Takifugu rubripes	34.45	3.00e-169	587.00
IUUC-Tsy-119201	Tarsius syrichta	35.63	5.00e-149	520.00
IUUC-Tni-120840	Tetraodon nigroviridis	35.40	4.00e-178	617.00
IUUC-Tca-121674	Theobroma cacao	35.73	8.00e-57	214.00
IUUC-Tae-125814	Triticum aestivum	26.00	9.00e-60	224.00
IUUC-Tur-126599	Triticum urartu	27.57	3.00e-56	212.00
IUUC-Tbe-127782	Tupaia belangeri	33.97	3.00e-96	345.00
IUUC-Ttr-128312	Tursiops truncatus	35.65	6.00e-162	563.00
IUUC-Vpa-130348	Vicugna pacos	36.17	7.00e-159	553.00
IUUC-Vvi-131353	Vitis vinifera	25.24	1.00e-62	233.00
IUUC-Xtr-132172	Xenopus tropicalis	34.26	4.00e-131	460.00
IUUC-Xma-133263	Xiphophorus maculatus	36.33	1.00e-168	585.00
IUUC-Yli-134636	Yarrowia lipolytica	27.12	8.00e-29	119.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence