iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000006101.2	ENSPANT00000024008.2	ENSPANP00000010984.1
ENSPANG00000006101.2	ENSPANT00000026781.1	ENSPANP00000017403.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.20e-08	35.4	12	53
E3 activity/RING/U-box	4.20e-08	33.2	7	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle f+d p++  CgH f++ Cl   w        + f CP Cr
   Q: 12   CPICLEYFQD-PVSIECGHNFCRGCLhRSW----APGGGPFPCPECR 53
           **********.***************9999....7799********8 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk..tcPvtrqplteedlvPnltlrrliqawc 69
            ee+ CpI le ++dPv +++G+ + r ++++  a gg    cP +r+p ++  l Pn +l rl ++ +
   Q: 7    QEELTCPICLEYFQDPVSIECGHNFCRGCLHRSWAPGGGpfPCPECRHPSAPAALRPNWALARLTEKTR 75
           6899**************************98555555559********************99988765 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MEAEDLQEEL TCPICLEYFQ DPVSIECGHN FCRGCLHRSW APGGGPFPCP ECRHPSAPAA 60
LRPNWALARL TEKTRRRRLG PVPPGLCSRH WEPLRLFCED DQRPVCLVCR ESQEHQTHAM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAGCTG AGGACCTCCA GGAGGAGTTG ACCTGCCCCA TCTGCCTGGA GTATTTCCAG 60
GACCCGGTGT CCATCGAGTG CGGCCACAAC TTTTGCCGCG GCTGCCTGCA CCGCAGTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:0008270--F:zinc ion binding
GO:0070206--P:protein trimerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002308	Ailuropoda melanoleuca	63.31	2.00e-159	555.00
IUUC-Cel-018621	Caenorhabditis elegans	36.26	9.00e-09	54.70
IUUC-Cja-019204	Callithrix jacchus	84.40	0.00e+00	840.00
IUUC-Cfa-021283	Canis familiaris	74.25	0.00e+00	722.00
IUUC-Csa-023476	Chlorocebus sabaeus	95.36	0.00e+00	917.00
IUUC-Cho-024657	Choloepus hoffmanni	62.70	3.00e-160	558.00
IUUC-Cne-027043	Cryptococcus neoformans	44.74	3.00e-06	46.60
IUUC-Eca-033740	Equus caballus	75.42	2.00e-154	538.00
IUUC-Hsa-046707	Homo sapiens	93.40	0.00e+00	936.00
IUUC-Mcc-055643	Macaca mulatta	96.57	0.00e+00	941.00
IUUC-Mmr-061318	Microcebus murinus	75.25	0.00e+00	754.00
IUUC-Mpu-066377	Mustela putorius furo	71.63	0.00e+00	678.00
IUUC-Mlu-067319	Myotis lucifugus	72.96	3.00e-144	504.00
IUUC-Nle-069382	Nomascus leucogenys	72.37	0.00e+00	669.00
IUUC-Opr-070278	Ochotona princeps	64.87	2.00e-175	608.00
IUUC-Oga-088830	Otolemur garnettii	66.20	4.00e-158	550.00
IUUC-Oar-089188	Ovis aries	71.23	0.00e+00	690.00
IUUC-Pab-097648	Pongo abelii	91.94	0.00e+00	897.00
IUUC-Pva-102131	Pteropus vampyrus	72.29	0.00e+00	709.00
IUUC-Ssc-116309	Sus scrofa	66.87	3.00e-174	604.00
IUUC-Tsy-119365	Tarsius syrichta	72.62	4.00e-132	464.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence