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Tag Content
iUUCD ID IUUC-Fca-036142
Ensembl Protein ID ENSFCAP00000022176.1
UniProt Accession M3X6C4; M3X6C4_FELCA
Genbank Protein ID ENSFCAP00000022176
Protein Name Uncharacterized protein
Genbank Nucleotide ID AANG02061227
Gene Name LATS1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFCAG00000023857.1 ENSFCAT00000027520.1 ENSFCAP00000022176.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBA 6.70e-08 32.5 100 137
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
    + ++l+ l++ GFd++ ++qaL+ + n ++eaA+e++
   Q: 100 NPQMLQDLQAAGFDEDMVIQALQKTnNRSIEAAIEFIS 137
    789*********************99*********975 PP
   

Organism Felis catus
Protein Sequence
(Fasta)
MKRSEKPEGY RQMRPKTFPA SNYSGSSRQM LQEIRESLRN LSKPSDAAKA EHNISKMSTE 60
DPRQVRNPPK FGTHHKALLE IRNSLQPFAN ETSRSTSEVN PQMLQDLQAA GFDEDMVIQA 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Fca-036142|UBD,UBA|Felis catus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAAGAGGA GTGAAAAGCC AGAAGGATAT AGACAAATGA GGCCTAAGAC CTTTCCTGCC 60
AGTAACTACT CTGGCAGTAG CCGGCAAATG TTGCAAGAAA TTCGGGAATC CCTTAGGAAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Fca-036142|UBD,UBA|Felis catus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR028741--LATS1/Warts
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0051220--P:cytoplasmic sequestering of protein
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0001827--P:inner cell mass cell fate commitment
GO:0001828--P:inner cell mass cellular morphogenesis
GO:0030216--P:keratinocyte differentiation
GO:0060644--P:mammary gland epithelial cell differentiation
GO:0007067--P:mitotic nuclear division
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0018105--P:peptidyl-serine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0030833--P:regulation of actin filament polymerization
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:0046620--P:regulation of organ growth
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0000819--P:sister chromatid segregation

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001895 Ailuropoda melanoleuca 93.17 0.00e+00 1934.00
IUUC-Apl-003278 Anas platyrhynchos 80.23 0.00e+00 1670.00
IUUC-Aca-005319 Anolis carolinensis 83.99 0.00e+00 1275.00
IUUC-Ame-011324 Astyanax mexicanus 84.96 0.00e+00 946.00
IUUC-Bta-013438 Bos taurus 91.49 0.00e+00 1853.00
IUUC-Cel-018517 Caenorhabditis elegans 50.32 4.00e-129 455.00
IUUC-Cja-019072 Callithrix jacchus 91.93 0.00e+00 1925.00
IUUC-Cfa-021267 Canis familiaris 93.70 0.00e+00 1959.00
IUUC-Cpo-021496 Cavia porcellus 85.67 0.00e+00 1536.00
IUUC-Csa-023255 Chlorocebus sabaeus 91.95 0.00e+00 1894.00
IUUC-Cho-024461 Choloepus hoffmanni 98.40 0.00e+00 788.00
IUUC-Cin-025264 Ciona intestinalis 63.68 1.00e-140 493.00
IUUC-Dre-028034 Danio rerio 82.50 0.00e+00 933.00
IUUC-Dno-029888 Dasypus novemcinctus 89.29 0.00e+00 1896.00
IUUC-Dor-030144 Dipodomys ordii 80.50 0.00e+00 1598.00
IUUC-Dme-031656 Drosophila melanogaster 73.66 0.00e+00 659.00
IUUC-Ete-032813 Echinops telfairi 94.70 0.00e+00 1236.00
IUUC-Eca-033781 Equus caballus 92.38 0.00e+00 1889.00
IUUC-Eeu-035007 Erinaceus europaeus 89.35 0.00e+00 1858.00
IUUC-Fal-036626 Ficedula albicollis 79.44 0.00e+00 1674.00
IUUC-Gmo-038688 Gadus morhua 85.99 0.00e+00 782.00
IUUC-Gga-040553 Gallus gallus 80.30 0.00e+00 1677.00
IUUC-Gac-042031 Gasterosteus aculeatus 61.78 0.00e+00 1200.00
IUUC-Ggo-045242 Gorilla gorilla 91.87 0.00e+00 1895.00
IUUC-Hsa-046081 Homo sapiens 91.77 0.00e+00 1892.00
IUUC-Itr-048668 Ictidomys tridecemlineatus 90.91 0.00e+00 1599.00
IUUC-Lch-049425 Latimeria chalumnae 73.37 0.00e+00 1538.00
IUUC-Loc-052418 Lepisosteus oculatus 64.79 0.00e+00 1270.00
IUUC-Laf-053710 Loxodonta africana 88.96 0.00e+00 1840.00
IUUC-Mcc-055079 Macaca mulatta 91.95 0.00e+00 1890.00
IUUC-Mga-059713 Meleagris gallopavo 79.72 0.00e+00 1676.00
IUUC-Mmr-061728 Microcebus murinus 91.87 0.00e+00 1916.00
IUUC-Mdo-061942 Monodelphis domestica 83.48 0.00e+00 1713.00
IUUC-Mmu-063504 Mus musculus 88.13 0.00e+00 1799.00
IUUC-Mpu-066034 Mustela putorius furo 92.55 0.00e+00 1915.00
IUUC-Mlu-067986 Myotis lucifugus 91.13 0.00e+00 1902.00
IUUC-Nle-069202 Nomascus leucogenys 91.68 0.00e+00 1894.00
IUUC-Opr-070801 Ochotona princeps 95.50 0.00e+00 1296.00
IUUC-Ont-072487 Oreochromis niloticus 59.42 0.00e+00 1161.00
IUUC-Oan-073128 Ornithorhynchus anatinus 88.90 0.00e+00 1329.00
IUUC-Ocu-073998 Oryctolagus cuniculus 97.32 0.00e+00 1450.00
IUUC-Ola-086858 Oryzias latipes 58.84 0.00e+00 1125.00
IUUC-Oga-088874 Otolemur garnettii 89.41 0.00e+00 1826.00
IUUC-Oar-089236 Ovis aries 91.41 0.00e+00 1856.00
IUUC-Ptr-091425 Pan troglodytes 92.12 0.00e+00 1904.00
IUUC-Pan-091851 Papio anubis 92.05 0.00e+00 1894.00
IUUC-Psi-093825 Pelodiscus sinensis 79.81 0.00e+00 1373.00
IUUC-Pfo-096326 Poecilia formosa 61.27 0.00e+00 1157.00
IUUC-Pab-097815 Pongo abelii 91.86 0.00e+00 1897.00
IUUC-Pva-102836 Pteropus vampyrus 91.05 0.00e+00 1806.00
IUUC-Ptt-103762 Puccinia triticina 37.78 7.00e-93 335.00
IUUC-Rno-106053 Rattus norvegicus 88.23 0.00e+00 1825.00
IUUC-Sha-106843 Sarcophilus harrisii 83.52 0.00e+00 1761.00
IUUC-Sar-113649 Sorex araneus 93.60 0.00e+00 1437.00
IUUC-Ssc-115486 Sus scrofa 97.86 0.00e+00 864.00
IUUC-Tgu-116903 Taeniopygia guttata 79.70 0.00e+00 1657.00
IUUC-Tru-118760 Takifugu rubripes 62.00 0.00e+00 1210.00
IUUC-Tsy-119361 Tarsius syrichta 90.94 0.00e+00 1613.00
IUUC-Tni-120058 Tetraodon nigroviridis 55.63 0.00e+00 1073.00
IUUC-Tbe-127681 Tupaia belangeri 95.98 0.00e+00 1471.00
IUUC-Ttr-128652 Tursiops truncatus 91.35 0.00e+00 1575.00
IUUC-Vpa-130538 Vicugna pacos 91.31 0.00e+00 1867.00
IUUC-Xtr-132895 Xenopus tropicalis 68.81 0.00e+00 1176.00
Created Date 25-Jun-2017

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