iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050110

Ensembl Protein ID

ENSLACP00000008353.1

UniProt Accession

H3AFD2; H3AFD2_LATCH

Genbank Protein ID

ENSLACP00000008353

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01080115

Gene Name

TLE3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000007395.1	ENSLACT00000008420.1	ENSLACP00000008353.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.60e-22	76.6	605	643

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 605  GHTDGASCIDIsHDgTKLWTGGLDNTVRSWDLREGRQLQ 643
           8**********9888*********************998 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MYPQGRHPAP HQPGQPGFKF TVAESCDRIK DEFQFLQAQY HSLKVEYDKL ANEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNTILA QIMPFLSQEH QQQVAQAVER AKQVTMTELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTAACGA TGTATCCTCA AGGCAGACAT CCGGTAAGTA TAAACCCTAT TATGAGTTTA 60
CTTTTTATCC CTTTTAAATG GATAGTTGTA AAGTTGCCAG GTATCTGTAA TGAAAGCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002200	Ailuropoda melanoleuca	92.95	0.00e+00	1287.00
IUUC-Aca-005074	Anolis carolinensis	89.92	0.00e+00	992.00
IUUC-Ame-010724	Astyanax mexicanus	88.69	0.00e+00	1257.00
IUUC-Bta-013189	Bos taurus	92.86	0.00e+00	1291.00
IUUC-Cja-018781	Callithrix jacchus	92.63	0.00e+00	1288.00
IUUC-Cfa-021016	Canis familiaris	90.86	0.00e+00	1182.00
IUUC-Cpo-021793	Cavia porcellus	92.03	0.00e+00	1269.00
IUUC-Csa-023928	Chlorocebus sabaeus	92.86	0.00e+00	1292.00
IUUC-Dre-028595	Danio rerio	91.10	0.00e+00	1237.00
IUUC-Dno-029736	Dasypus novemcinctus	87.66	0.00e+00	1153.00
IUUC-Ete-032685	Echinops telfairi	89.70	0.00e+00	1198.00
IUUC-Eca-033249	Equus caballus	92.34	0.00e+00	1271.00
IUUC-Fca-036239	Felis catus	91.41	0.00e+00	1155.00
IUUC-Gmo-039000	Gadus morhua	85.27	0.00e+00	1137.00
IUUC-Gac-041924	Gasterosteus aculeatus	91.02	0.00e+00	1228.00
IUUC-Ggo-044458	Gorilla gorilla	92.38	0.00e+00	1306.00
IUUC-Hsa-046549	Homo sapiens	92.76	0.00e+00	1291.00
IUUC-Loc-052165	Lepisosteus oculatus	94.11	0.00e+00	1294.00
IUUC-Laf-053817	Loxodonta africana	91.59	0.00e+00	1295.00
IUUC-Mcc-055673	Macaca mulatta	90.42	0.00e+00	1285.00
IUUC-Meu-056601	Macropus eugenii	92.21	0.00e+00	1293.00
IUUC-Mga-059792	Meleagris gallopavo	82.64	0.00e+00	989.00
IUUC-Mmr-060904	Microcebus murinus	90.68	0.00e+00	1286.00
IUUC-Mdo-061897	Monodelphis domestica	90.37	0.00e+00	1271.00
IUUC-Mmu-063702	Mus musculus	90.31	0.00e+00	1250.00
IUUC-Mpu-066618	Mustela putorius furo	92.60	0.00e+00	1288.00
IUUC-Mlu-067934	Myotis lucifugus	92.56	0.00e+00	1283.00
IUUC-Nle-069452	Nomascus leucogenys	92.86	0.00e+00	1292.00
IUUC-Ont-071865	Oreochromis niloticus	91.53	0.00e+00	1267.00
IUUC-Ocu-074091	Oryctolagus cuniculus	92.31	0.00e+00	1249.00
IUUC-Ola-086424	Oryzias latipes	90.61	0.00e+00	1249.00
IUUC-Oga-088548	Otolemur garnettii	91.47	0.00e+00	1292.00
IUUC-Oar-089856	Ovis aries	91.64	0.00e+00	1275.00
IUUC-Ptr-090848	Pan troglodytes	92.86	0.00e+00	1291.00
IUUC-Pan-092288	Papio anubis	93.08	0.00e+00	1290.00
IUUC-Psi-093427	Pelodiscus sinensis	92.76	0.00e+00	1264.00
IUUC-Pma-094452	Petromyzon marinus	77.37	0.00e+00	1095.00
IUUC-Pfo-096613	Poecilia formosa	91.16	0.00e+00	1283.00
IUUC-Pab-098175	Pongo abelii	92.99	0.00e+00	1294.00
IUUC-Pca-100321	Procavia capensis	91.72	0.00e+00	1286.00
IUUC-Pva-102741	Pteropus vampyrus	85.79	0.00e+00	1167.00
IUUC-Rno-104864	Rattus norvegicus	92.82	0.00e+00	1276.00
IUUC-Sha-106568	Sarcophilus harrisii	92.00	0.00e+00	1280.00
IUUC-Sar-113414	Sorex araneus	92.64	5.00e-180	624.00
IUUC-Ssc-116160	Sus scrofa	91.63	0.00e+00	1274.00
IUUC-Tru-117982	Takifugu rubripes	85.21	0.00e+00	1252.00
IUUC-Tni-120823	Tetraodon nigroviridis	91.76	0.00e+00	1276.00
IUUC-Ttr-128845	Tursiops truncatus	91.98	0.00e+00	1298.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence