iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088041

Ensembl Protein ID

ENSOGAP00000017572.1

UniProt Accession

H0XN81; H0XN81_OTOGA

Genbank Protein ID

ENSOGAP00000017572

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03041172

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000032054.1	ENSOGAT00000029015.1	ENSOGAP00000017572.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	92.89	2.00e-108	388.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL 60
SAEPAGTFLI RDSSDQRHFF TLSVKTQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCTTCCTC CCCGCAGCCC CCCGGGATGC AGTAGCGGCC GCTGTGAGGA GGCCGCGAAG 60
CAGCTGCAGC CGCCACCGCG CAGATCCACG CTGGCTCCGT GCGCCATGGT CACCCACAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0060670--P:branching involved in labyrinthine layer morphogenesis
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0060674--P:placenta blood vessel development
GO:0045597--P:positive regulation of cell differentiation
GO:0016567--P:protein ubiquitination
GO:0060708--P:spongiotrophoblast differentiation
GO:0060707--P:trophoblast giant cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	89.33	2.00e-105	374.00
IUUC-Apl-003607	Anas platyrhynchos	82.14	4.00e-95	340.00
IUUC-Aca-005063	Anolis carolinensis	81.50	8.00e-102	362.00
IUUC-Ath-006990	Arabidopsis thaliana	32.94	1.80e-02	35.00
IUUC-Ame-010859	Astyanax mexicanus	56.77	1.00e-67	248.00
IUUC-Bta-012817	Bos taurus	88.65	2.00e-109	387.00
IUUC-Bra-017963	Brassica rapa	30.00	9.30e-02	31.60
IUUC-Cja-019605	Callithrix jacchus	91.11	3.00e-113	400.00
IUUC-Cfa-021231	Canis familiaris	90.67	3.00e-107	380.00
IUUC-Cpo-022003	Cavia porcellus	89.47	7.00e-107	379.00
IUUC-Csa-023511	Chlorocebus sabaeus	91.11	2.00e-111	394.00
IUUC-Dre-028536	Danio rerio	58.95	4.00e-71	260.00
IUUC-Dno-029003	Dasypus novemcinctus	91.07	2.00e-109	388.00
IUUC-Eca-034205	Equus caballus	82.68	9.00e-68	248.00
IUUC-Fca-036317	Felis catus	90.13	4.00e-107	380.00
IUUC-Gmo-038777	Gadus morhua	63.89	8.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	83.04	6.00e-95	339.00
IUUC-Gac-041837	Gasterosteus aculeatus	55.70	6.00e-64	236.00
IUUC-Ggo-045620	Gorilla gorilla	91.11	2.00e-111	394.00
IUUC-Hsa-046909	Homo sapiens	91.11	2.00e-111	394.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	88.89	2.00e-113	401.00
IUUC-Lch-049510	Latimeria chalumnae	67.98	1.00e-82	298.00
IUUC-Loc-052863	Lepisosteus oculatus	61.80	5.00e-77	280.00
IUUC-Laf-054136	Loxodonta africana	89.04	8.00e-109	385.00
IUUC-Mcc-055383	Macaca mulatta	91.11	2.00e-111	394.00
IUUC-Meu-056153	Macropus eugenii	86.73	1.00e-109	388.00
IUUC-Mmr-061185	Microcebus murinus	91.15	1.00e-106	378.00
IUUC-Mdo-061819	Monodelphis domestica	88.89	1.00e-110	391.00
IUUC-Mmu-064231	Mus musculus	96.00	3.00e-113	400.00
IUUC-Mpu-066691	Mustela putorius furo	90.67	3.00e-107	380.00
IUUC-Mlu-067673	Myotis lucifugus	90.27	7.00e-113	399.00
IUUC-Ont-072406	Oreochromis niloticus	55.26	6.00e-68	249.00
IUUC-Oan-073249	Ornithorhynchus anatinus	76.79	2.00e-93	334.00
IUUC-Ocu-074935	Oryctolagus cuniculus	88.41	2.00e-32	129.00
IUUC-Ola-087373	Oryzias latipes	47.32	1.00e-47	182.00
IUUC-Oar-089646	Ovis aries	87.34	9.00e-103	365.00
IUUC-Ptr-091502	Pan troglodytes	91.11	2.00e-111	394.00
IUUC-Pan-091934	Papio anubis	91.11	2.00e-111	394.00
IUUC-Pfo-096412	Poecilia formosa	42.11	2.00e-47	181.00
IUUC-Pab-098554	Pongo abelii	91.11	2.00e-111	394.00
IUUC-Rno-105874	Rattus norvegicus	95.56	4.00e-113	400.00
IUUC-Sha-107151	Sarcophilus harrisii	86.40	4.00e-109	387.00
IUUC-Ssc-115722	Sus scrofa	87.72	8.00e-66	242.00
IUUC-Tgu-117151	Taeniopygia guttata	82.59	4.00e-94	337.00
IUUC-Tru-118428	Takifugu rubripes	54.82	1.00e-67	248.00
IUUC-Tni-120590	Tetraodon nigroviridis	54.82	2.00e-66	244.00
IUUC-Ttr-129065	Tursiops truncatus	89.52	5.00e-111	393.00
IUUC-Xtr-132167	Xenopus tropicalis	66.52	6.00e-81	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence