iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Sce-106260

UUCD1 version

UUC-SaC-00078

Ensembl Protein ID

YDR255C

UniProt Accession

Q12508; D6VSN5; RMD5_YEAST

Genbank Protein ID

CAA94094.1; CAA92712.1; AAS56122.1; DAA12095.1

Protein Name

Sporulation protein RMD5; Glucose-induced degradation protein 2; Required for meiotic nuclear division protein 5

Genbank Nucleotide ID

Z70202; Z68329; AY557796; BK006938

Gene Name

RMD5; GID2; YDR255C; YD9320A.05c

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YDR255C	YDR255C	YDR255C

Annotation

mRNA Expression
GEO	FFGED
Protein-protein Interaction
iRefIndex	Mentha
Post-translational Modifications (PTMs)
BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	18508925

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	0.0021	17.0	368	404

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 8    f..kdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
              +++p++l C H++ ++ l ++   +++   +f+CP+C
   Q: 368  TttENPPYSLACHHIISKKALDRL---SKNGTITFKCPYC 404
           3557789**************999...777999******* PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Has a role in the negative regulation of gluconeogenesis. Required for proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase). Required specifically for the ubiquitination of FBPase. Also required for sporulation.

Protein Sequence
(Fasta)

MSELLDSFET EFAKFYTDSN LEETNLQKCL DHTHEFKSQL KKLKAHLNKH IQESKPEVYN 60
KLSDKEKQKF KRKRELIIEK LSKSQRQWDH SVKKQIKYVS QQSNRFNKST LNKLKEFDID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGAAT TACTAGATAG CTTTGAGACA GAGTTTGCGA AATTTTATAC CGACAGCAAT 60
CTGGAAGAGA CAAACCTTCA AAAATGTCTT GATCATACTC ATGAATTCAA GAGTCAATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0469--Meiosis
KW-1185--Reference proteome
KW-0749--Sporulation
KW-0833--Ubl conjugation pathway

Interpro

IPR024964--CTLH/CRA
IPR006595--CTLH_C
IPR027711--Rmd5
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50897--CTLH

Pfam

PF10607--CLTH

SMART

SM00668--CTLH

Gene Ontology

GO:0005829--C:cytosol
GO:0034657--C:GID complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0051321--P:meiotic cell cycle
GO:0045721--P:negative regulation of gluconeogenesis
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030435--P:sporulation resulting in formation of a cellular spore

KEGG

sce:YDR255C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000501	Aegilops tauschii	29.27	4.00e-25	107.00
IUUC-Aml-001548	Ailuropoda melanoleuca	25.60	1.00e-25	108.00
IUUC-Atr-003004	Amborella trichopoda	26.53	4.00e-24	103.00
IUUC-Apl-003644	Anas platyrhynchos	26.95	1.00e-24	104.00
IUUC-Aca-005137	Anolis carolinensis	27.02	6.00e-22	96.30
IUUC-Aly-005615	Arabidopsis lyrata	31.05	7.00e-29	119.00
IUUC-Ath-007247	Arabidopsis thaliana	28.24	4.00e-27	113.00
IUUC-Ago-007826	Ashbya gossypii	45.28	3.00e-90	323.00
IUUC-Acl-008282	Aspergillus clavatus	25.07	1.00e-27	115.00
IUUC-Afl-008705	Aspergillus flavus	26.12	1.00e-28	118.00
IUUC-Afu-009079	Aspergillus fumigatus	42.06	9.00e-27	112.00
IUUC-Ani-009387	Aspergillus nidulans	30.62	6.00e-29	119.00
IUUC-Ang-009525	Aspergillus niger	36.23	4.00e-09	53.90
IUUC-Aor-009954	Aspergillus oryzae	26.12	1.00e-28	118.00
IUUC-Ate-010352	Aspergillus terreus	30.12	4.00e-27	114.00
IUUC-Ame-011850	Astyanax mexicanus	25.42	3.00e-27	114.00
IUUC-Bgr-012198	Blumeria graminis	27.54	4.00e-28	116.00
IUUC-Bta-013363	Bos taurus	25.60	1.00e-25	108.00
IUUC-Bci-013985	Botrytis cinerea	30.70	4.00e-31	127.00
IUUC-Bdi-014918	Brachypodium distachyon	27.87	9.00e-25	105.00
IUUC-Bol-015549	Brassica oleracea	29.76	4.00e-26	110.00
IUUC-Bra-017752	Brassica rapa	29.37	5.00e-27	112.00
IUUC-Cel-018146	Caenorhabditis elegans	27.49	2.00e-14	71.20
IUUC-Cja-019683	Callithrix jacchus	25.60	6.00e-25	106.00
IUUC-Cfa-020186	Canis familiaris	25.60	1.00e-25	108.00
IUUC-Cpo-021863	Cavia porcellus	25.60	1.00e-25	108.00
IUUC-Cre-022621	Chlamydomonas reinhardtii	33.59	3.00e-21	92.00
IUUC-Csa-023778	Chlorocebus sabaeus	25.60	1.00e-25	108.00
IUUC-Cho-024394	Choloepus hoffmanni	46.88	2.00e-14	71.20
IUUC-Cin-025509	Ciona intestinalis	27.37	2.00e-26	110.00
IUUC-Csv-025906	Ciona savignyi	27.27	2.00e-31	127.00
IUUC-Cgl-026770	Colletotrichum gloeosporioides	26.77	3.00e-27	114.00
IUUC-Cne-026984	Cryptococcus neoformans	42.70	2.00e-18	84.30
IUUC-Cme-027169	Cyanidioschyzon merolae	36.52	3.00e-20	90.90
IUUC-Dre-027541	Danio rerio	27.42	1.00e-24	105.00
IUUC-Dno-028947	Dasypus novemcinctus	27.53	2.00e-24	103.00
IUUC-Dor-030778	Dipodomys ordii	27.94	2.00e-24	105.00
IUUC-Dse-031216	Dothistroma septosporum	39.67	6.00e-21	93.20
IUUC-Dme-032053	Drosophila melanogaster	26.18	1.00e-24	105.00
IUUC-Ete-033138	Echinops telfairi	30.52	1.00e-22	98.60
IUUC-Eca-034297	Equus caballus	25.60	1.00e-25	108.00
IUUC-Eeu-034733	Erinaceus europaeus	20.93	5.00e-02	32.00
IUUC-Fca-035452	Felis catus	28.23	3.00e-24	103.00
IUUC-Fal-037162	Ficedula albicollis	26.95	1.00e-24	105.00
IUUC-Fox-037791	Fusarium oxysporum	37.80	1.00e-26	111.00
IUUC-Fso-038261	Fusarium solani	29.53	3.00e-29	120.00
IUUC-Gmo-038538	Gadus morhua	28.23	6.00e-26	109.00
IUUC-Ggr-039758	Gaeumannomyces graminis	30.04	5.00e-28	116.00
IUUC-Gga-040152	Gallus gallus	26.95	1.00e-24	105.00
IUUC-Gac-042375	Gasterosteus aculeatus	28.63	4.00e-26	110.00
IUUC-Gma-043473	Glycine max	26.67	5.00e-26	109.00
IUUC-Ggo-044610	Gorilla gorilla	28.80	5.00e-24	103.00
IUUC-Hsa-046828	Homo sapiens	25.60	1.00e-25	108.00
IUUC-Hvu-047623	Hordeum vulgare	24.53	3.00e-26	110.00
IUUC-Itr-048574	Ictidomys tridecemlineatus	25.60	1.00e-25	108.00
IUUC-Kpa-049125	Komagataella pastoris	28.97	6.00e-30	122.00
IUUC-Lch-049725	Latimeria chalumnae	27.46	9.00e-25	105.00
IUUC-Lpe-051452	Leersia perrieri	27.05	1.00e-24	105.00
IUUC-Loc-052201	Lepisosteus oculatus	28.63	6.00e-25	106.00
IUUC-Lma-053061	Leptosphaeria maculans	26.75	4.00e-32	130.00
IUUC-Laf-054447	Loxodonta africana	27.53	1.00e-24	105.00
IUUC-Mcc-055378	Macaca mulatta	25.60	1.00e-25	108.00
IUUC-Meu-056571	Macropus eugenii	28.63	5.00e-25	106.00
IUUC-Mor-056969	Magnaporthe oryzae	32.31	2.00e-29	121.00
IUUC-Mpo-057427	Magnaporthe poae	30.04	6.00e-28	116.00
IUUC-Mtr-058293	Medicago truncatula	25.96	4.00e-26	110.00
IUUC-Mla-059074	Melampsora laricipopulina	36.64	5.00e-21	93.60
IUUC-Mga-059978	Meleagris gallopavo	26.95	1.00e-24	105.00
IUUC-Mvi-060298	Microbotryum violaceum	35.38	2.00e-20	91.30
IUUC-Mmr-061460	Microcebus murinus	25.72	4.00e-25	107.00
IUUC-Mdo-061921	Monodelphis domestica	28.63	1.00e-22	100.00
IUUC-Mmu-063553	Mus musculus	25.60	1.00e-25	108.00
IUUC-Mac-064452	Musa acuminata	30.77	4.00e-29	120.00
IUUC-Mpu-066545	Mustela putorius furo	25.60	1.00e-25	108.00
IUUC-Mlu-067713	Myotis lucifugus	28.92	5.00e-24	103.00
IUUC-Nfi-068340	Neosartorya fischeri	42.06	1.00e-26	112.00
IUUC-Ncr-068889	Neurospora crassa	29.70	3.00e-27	114.00
IUUC-Nle-069876	Nomascus leucogenys	27.13	5.00e-24	103.00
IUUC-Opr-070502	Ochotona princeps	25.51	2.00e-19	87.40
IUUC-Ont-072436	Oreochromis niloticus	28.23	7.00e-26	109.00
IUUC-Oan-072730	Ornithorhynchus anatinus	26.95	3.00e-24	103.00
IUUC-Ocu-073997	Oryctolagus cuniculus	25.60	1.00e-25	108.00
IUUC-Oba-075935	Oryza barthii	26.94	7.00e-24	102.00
IUUC-Ogl-077599	Oryza glaberrima	26.94	7.00e-24	102.00
IUUC-Ogu-079031	Oryza glumaepatula	26.94	7.00e-24	102.00
IUUC-Oin-079236	Oryza indica	26.94	8.00e-24	102.00
IUUC-Olo-080825	Oryza longistaminata	26.94	7.00e-24	102.00
IUUC-Ome-081998	Oryza meridionalis	26.94	7.00e-24	102.00
IUUC-Oni-082555	Oryza nivara	26.94	8.00e-24	102.00
IUUC-Opu-084156	Oryza punctata	26.94	4.00e-23	100.00
IUUC-Oru-085269	Oryza rufipogon	26.94	8.00e-24	102.00
IUUC-Osa-085795	Oryza sativa	26.94	8.00e-24	102.00
IUUC-Ola-087481	Oryzias latipes	27.71	4.00e-24	103.00
IUUC-Oga-088917	Otolemur garnettii	25.60	1.00e-25	108.00
IUUC-Oar-090104	Ovis aries	25.60	1.00e-25	108.00
IUUC-Ptr-090545	Pan troglodytes	28.80	5.00e-24	103.00
IUUC-Pan-091970	Papio anubis	25.60	1.00e-25	108.00
IUUC-Psi-093133	Pelodiscus sinensis	26.95	1.00e-24	104.00
IUUC-Pma-094313	Petromyzon marinus	23.50	8.00e-22	95.50
IUUC-Pno-094966	Phaeosphaeria nodorum	26.90	2.00e-32	131.00
IUUC-Ppa-095263	Physcomitrella patens	29.84	3.00e-26	110.00
IUUC-Pfo-096415	Poecilia formosa	27.89	3.00e-24	103.00
IUUC-Pab-098226	Pongo abelii	25.60	1.00e-25	108.00
IUUC-Pop-099161	Populus trichocarpa	27.55	7.00e-30	122.00
IUUC-Pca-100101	Procavia capensis	35.51	8.00e-18	82.80
IUUC-Ppe-101172	Prunus persica	27.11	3.00e-30	123.00
IUUC-Pva-102124	Pteropus vampyrus	28.51	9.00e-22	95.50
IUUC-Pgr-103586	Puccinia graminis	40.15	4.00e-20	90.50
IUUC-Ptt-103906	Puccinia triticina	24.26	1.00e-02	31.60
IUUC-Pte-104149	Pyrenophora teres	27.67	2.00e-31	128.00
IUUC-Pyt-104577	Pyrenophora triticirepentis	30.37	2.00e-30	124.00
IUUC-Rno-105160	Rattus norvegicus	25.60	1.00e-25	108.00
IUUC-Sha-107085	Sarcophilus harrisii	28.63	5.00e-25	106.00
IUUC-Sja-107986	Schizosaccharomyces japonicus	34.65	9.00e-20	89.00
IUUC-Spo-108054	Schizosaccharomyces pombe	40.41	9.00e-31	125.00
IUUC-Ssl-108439	Sclerotinia sclerotiorum	30.18	1.00e-29	121.00
IUUC-Smo-109084	Selaginella moellendorffii	28.51	2.00e-23	101.00
IUUC-Sit-109808	Setaria italica	28.97	4.00e-25	106.00
IUUC-Sly-111578	Solanum lycopersicum	25.57	3.00e-22	97.40
IUUC-Stu-112255	Solanum tuberosum	25.57	2.00e-22	97.80
IUUC-Sar-113433	Sorex araneus	39.81	2.00e-18	84.00
IUUC-Sbi-114206	Sorghum bicolor	28.80	1.00e-25	108.00
IUUC-Sre-115108	Sporisorium reilianum	38.27	3.00e-23	100.00
IUUC-Ssc-115466	Sus scrofa	28.63	5.00e-24	102.00
IUUC-Tgu-116744	Taeniopygia guttata	26.95	1.00e-24	105.00
IUUC-Tru-118729	Takifugu rubripes	27.82	5.00e-25	106.00
IUUC-Tsy-119164	Tarsius syrichta	28.63	4.00e-24	103.00
IUUC-Tni-119975	Tetraodon nigroviridis	27.82	6.00e-25	106.00
IUUC-Tca-121086	Theobroma cacao	28.81	2.00e-22	98.20
IUUC-Tre-122252	Trichoderma reesei	26.39	2.00e-19	87.80
IUUC-Tvi-122591	Trichoderma virens	25.65	9.00e-19	85.90
IUUC-Tae-122825	Triticum aestivum	29.27	1.00e-25	108.00
IUUC-Tur-126299	Triticum urartu	28.57	4.00e-25	107.00
IUUC-Tme-127008	Tuber melanosporum	30.68	1.00e-27	114.00
IUUC-Tbe-128119	Tupaia belangeri	25.81	3.00e-25	107.00
IUUC-Ttr-128810	Tursiops truncatus	27.53	3.00e-24	104.00
IUUC-Uma-129656	Ustilago maydis	37.04	2.00e-23	102.00
IUUC-Vda-129967	Verticillium dahliae	28.43	2.00e-29	121.00
IUUC-Vvi-131145	Vitis vinifera	29.03	5.00e-27	113.00
IUUC-Xtr-132522	Xenopus tropicalis	28.52	4.00e-23	100.00
IUUC-Xma-134046	Xiphophorus maculatus	28.23	5.00e-26	109.00
IUUC-Yli-134400	Yarrowia lipolytica	29.67	7.00e-28	115.00
IUUC-Zma-134785	Zea mays	28.80	6.00e-26	109.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence