iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009148

Ensembl Protein ID

CADANIAP00006373

UniProt Accession

C8VA49; C8VA49_EMENI

Genbank Protein ID

CBF78212.1

Protein Name

Ubiquitin C-terminal hydrolase, putative (AFU_orthologue AFUA_6G02380)

Genbank Nucleotide ID

BN001303

Gene Name

ANIA_11102

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00006373	CADANIAT00006373	CADANIAP00006373

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.70e-57	192.8	112	565
ULD/UDP/UBQ/UBQ_Other	2.80e-09	35.8	11	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenp...........kepkgellkslqklfeelwkskkkavsprellkalkkeae 82
           Gl+NlgNtCY+NS+LQ+L ++pel e l + + +++++  ++            + + +l+++l++lf+++ +++++ + p  +l+al+++ +
   Q: 112  GLQNLGNTCYLNSTLQTLRSVPELHEELQRyRPSRNISGASNlsnlsdfglggLGASMDLTSALRDLFKQM-SETQEGFPPILFLNALRNVFP 203
           9*****************************6555555555546666666666666677*************.99999**************** PP
   S: 83   efs.......gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikc.....lecdnvs 163
           +f        gy+qqDa+E ++++++ql+++l        +               e +   + s++++ ++g+++s + c     +e +++ 
   Q: 204  QFAqqdrnghGYAQQDAEEAWSQIVSQLRQKLVI------K-------------DGEGESATEVSFVEKYMGGRFESVTECdepaaKEAGEQP 277
           **999***************************11......1.............2345667788****************9444443344444 PP
   S: 164  .sreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvef 255
            ++ + f++l +++ ++++     l+d + s   ee++e     ++++ +++   +k+ ++ +lP++L++h+ Rf ++++ +++ ki +kv+f
   Q: 278  nKTSDVFFKLDCHIDKETN----HLHDGILSGL-EEKIE----KHSPTLNRDAVYTKRSRIARLPKYLTVHFVRFFWKRDAQKKAKIMRKVTF 361
           4788889999999988886....5777664433.56777....599*********************************************** PP
   S: 256  pleLdlspfcts.............................................................peekqke............. 274
           p eLd+  fct+                                                             +     e             
   Q: 362  PAELDVLDFCTDelkkqlipvrdkvrdirkeeldierarkrqkiarqreedaktdnasslepmqkkkateerkE-----Egtnsgkdedaamt 449
           ************88888888888888888888887777777777777777777766666666666655555550.....05555555556666 PP
   S: 275  ........................................kkkYeLiavvvHsG.slssGHYvayvkn........ekgkWllfdDskVtevk 318
                                                   +  YeL +v+ H+G s++sGHY++yvk+        +++kW+ f+D+kVtev+
   Q: 450  dvfktdaeyeaekqasitaakkelaqlidpklgadsgtnkTGLYELRGVITHQGaSADSGHYTSYVKKqgsnskeeRDDKWWWFNDDKVTEVD 542
           66666666666666666666666777777777777777769***************************777666544666************* PP
   S: 319  eeevleetg....staYvlfYkr 337
            +++++  g    ++a +l+Y+ 
   Q: 543  GSKIETLAGggesHSALILLYRA 565
           ******8889***********85 PP

ULD/UDP/UBQ/UBQ_Other

   S: 9    dgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
           +g++++++++p +t  ++K ++++++g+ pe+q++++kG  L++d  L+  ++k+++t++++ + s
   Q: 11   QGKRYDVELDPNSTGETFKYQLYSLTGVEPERQKILVKGGQLKNDTLLSTINAKPNQTFMMMGTPS 76
           7889*********************************************************98865 PP

Organism

Aspergillus nidulans

Protein Sequence
(Fasta)

MASIPVIVKH QGKRYDVELD PNSTGETFKY QLYSLTGVEP ERQKILVKGG QLKNDTLLST 60
INAKPNQTFM MMGTPSGDQG AGALTRPKEV VKFLEDMTEA EAAKAAGAIP AGLQNLGNTC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTGCAAAGC ACTTTTTCAC GTCCAGAGTG ACGACAAGAC GTCAAAATGG CCTCTATACC 60
AGGTATGGCC CTAAACGATC ATGTATTGCG ACTTTGACAG CAACGTAGCT GACTCTACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00240--ubiquitin
PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005838--C:proteasome regulatory particle
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1901799--P:negative regulation of proteasomal protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	29.18	6.00e-30	124.00
IUUC-Aml-002053	Ailuropoda melanoleuca	37.03	1.00e-66	245.00
IUUC-Atr-002725	Amborella trichopoda	36.61	5.00e-74	270.00
IUUC-Apl-004031	Anas platyrhynchos	34.62	2.00e-71	261.00
IUUC-Aca-004361	Anolis carolinensis	35.91	6.00e-86	309.00
IUUC-Aly-006176	Arabidopsis lyrata	36.93	1.00e-85	308.00
IUUC-Ath-007658	Arabidopsis thaliana	35.93	5.00e-85	306.00
IUUC-Ago-007796	Ashbya gossypii	33.39	7.00e-79	286.00
IUUC-Acl-008258	Aspergillus clavatus	79.27	0.00e+00	846.00
IUUC-Afl-008732	Aspergillus flavus	81.99	0.00e+00	921.00
IUUC-Afu-008755	Aspergillus fumigatus	80.49	0.00e+00	861.00
IUUC-Ang-009878	Aspergillus niger	80.94	0.00e+00	895.00
IUUC-Aor-010239	Aspergillus oryzae	82.17	0.00e+00	924.00
IUUC-Ate-010243	Aspergillus terreus	78.63	0.00e+00	874.00
IUUC-Ame-011327	Astyanax mexicanus	28.00	5.00e-16	77.40
IUUC-Bgr-012231	Blumeria graminis	63.36	0.00e+00	720.00
IUUC-Bta-012553	Bos taurus	38.63	2.00e-68	251.00
IUUC-Bci-013606	Botrytis cinerea	65.34	0.00e+00	697.00
IUUC-Bdi-014567	Brachypodium distachyon	38.25	9.00e-81	292.00
IUUC-Bol-015565	Brassica oleracea	37.77	1.00e-86	311.00
IUUC-Bra-017297	Brassica rapa	37.59	4.00e-85	306.00
IUUC-Cel-018140	Caenorhabditis elegans	31.27	5.00e-62	229.00
IUUC-Cja-019516	Callithrix jacchus	37.41	4.00e-67	246.00
IUUC-Cfa-020808	Canis familiaris	37.74	3.00e-68	250.00
IUUC-Cpo-021688	Cavia porcellus	35.84	3.00e-77	280.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	34.28	4.00e-47	180.00
IUUC-Csa-023429	Chlorocebus sabaeus	37.03	2.00e-65	241.00
IUUC-Cho-024347	Choloepus hoffmanni	37.97	3.00e-67	248.00
IUUC-Cin-025198	Ciona intestinalis	37.34	1.00e-56	212.00
IUUC-Csv-026007	Ciona savignyi	37.31	6.00e-58	216.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	58.29	1.00e-168	584.00
IUUC-Cne-026963	Cryptococcus neoformans	35.94	5.00e-80	289.00
IUUC-Cme-027240	Cyanidioschyzon merolae	34.38	1.00e-50	192.00
IUUC-Dre-027647	Danio rerio	36.33	1.00e-88	318.00
IUUC-Dno-029967	Dasypus novemcinctus	34.66	3.00e-76	277.00
IUUC-Dor-030886	Dipodomys ordii	33.62	3.00e-41	161.00
IUUC-Dse-031466	Dothistroma septosporum	55.70	2.00e-157	547.00
IUUC-Dme-032079	Drosophila melanogaster	32.63	3.00e-75	274.00
IUUC-Ete-032351	Echinops telfairi	36.17	2.00e-60	224.00
IUUC-Eca-033461	Equus caballus	38.21	5.00e-73	266.00
IUUC-Eeu-035220	Erinaceus europaeus	33.24	2.00e-39	155.00
IUUC-Fca-036210	Felis catus	37.97	1.00e-68	252.00
IUUC-Fal-037528	Ficedula albicollis	35.02	6.00e-76	276.00
IUUC-Fox-037805	Fusarium oxysporum	59.97	0.00e+00	643.00
IUUC-Fso-038177	Fusarium solani	60.83	0.00e+00	649.00
IUUC-Gmo-038953	Gadus morhua	38.83	3.00e-71	260.00
IUUC-Ggr-039972	Gaeumannomyces graminis	58.06	5.00e-177	612.00
IUUC-Gga-040462	Gallus gallus	38.63	7.00e-66	243.00
IUUC-Gac-041312	Gasterosteus aculeatus	38.65	3.00e-69	254.00
IUUC-Gma-043255	Glycine max	38.19	5.00e-86	309.00
IUUC-Ggo-045458	Gorilla gorilla	33.42	2.00e-44	171.00
IUUC-Hsa-045706	Homo sapiens	37.03	9.00e-66	242.00
IUUC-Hvu-047821	Hordeum vulgare	43.72	3.00e-38	150.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	38.14	4.00e-69	253.00
IUUC-Lch-050464	Latimeria chalumnae	35.55	3.00e-84	303.00
IUUC-Lpe-051419	Leersia perrieri	37.97	7.00e-82	295.00
IUUC-Loc-052732	Lepisosteus oculatus	37.50	2.00e-73	268.00
IUUC-Lma-053177	Leptosphaeria maculans	64.88	0.00e+00	674.00
IUUC-Laf-053822	Loxodonta africana	37.74	3.00e-68	250.00
IUUC-Mcc-055893	Macaca mulatta	37.03	1.00e-65	242.00
IUUC-Meu-056307	Macropus eugenii	35.71	2.00e-59	221.00
IUUC-Mor-057171	Magnaporthe oryzae	58.65	0.00e+00	640.00
IUUC-Mpo-057415	Magnaporthe poae	59.07	0.00e+00	633.00
IUUC-Mtr-057901	Medicago truncatula	36.93	4.00e-84	303.00
IUUC-Mla-058897	Melampsora laricipopulina	39.83	1.00e-94	338.00
IUUC-Mga-060016	Meleagris gallopavo	38.61	1.00e-65	241.00
IUUC-Mvi-060562	Microbotryum violaceum	37.37	4.00e-87	313.00
IUUC-Mmr-060624	Microcebus murinus	38.21	2.00e-72	264.00
IUUC-Mdo-061809	Monodelphis domestica	35.75	3.00e-81	293.00
IUUC-Mmu-063869	Mus musculus	39.36	7.00e-68	249.00
IUUC-Mac-064876	Musa acuminata	34.81	1.00e-71	262.00
IUUC-Mpu-066480	Mustela putorius furo	37.97	6.00e-69	253.00
IUUC-Mlu-067866	Myotis lucifugus	35.53	4.00e-81	293.00
IUUC-Nfi-068393	Neosartorya fischeri	80.14	0.00e+00	884.00
IUUC-Ncr-068815	Neurospora crassa	60.83	0.00e+00	652.00
IUUC-Nle-070121	Nomascus leucogenys	43.10	3.00e-40	157.00
IUUC-Opr-070712	Ochotona princeps	32.76	1.00e-30	125.00
IUUC-Ont-071544	Oreochromis niloticus	39.95	4.00e-70	256.00
IUUC-Oan-073635	Ornithorhynchus anatinus	33.92	2.00e-60	224.00
IUUC-Ocu-074926	Oryctolagus cuniculus	35.24	2.00e-76	277.00
IUUC-Oba-075633	Oryza barthii	35.65	3.00e-71	260.00
IUUC-Obr-076423	Oryza brachyantha	37.61	1.00e-82	298.00
IUUC-Ogl-077913	Oryza glaberrima	37.97	4.00e-79	286.00
IUUC-Ogu-078435	Oryza glumaepatula	35.65	3.00e-71	260.00
IUUC-Oin-080072	Oryza indica	35.65	2.00e-71	261.00
IUUC-Olo-080535	Oryza longistaminata	34.22	8.00e-69	252.00
IUUC-Ome-081309	Oryza meridionalis	35.65	3.00e-71	260.00
IUUC-Oni-083113	Oryza nivara	35.65	3.00e-71	260.00
IUUC-Opu-083168	Oryza punctata	34.94	6.00e-67	246.00
IUUC-Oru-084253	Oryza rufipogon	35.65	3.00e-71	260.00
IUUC-Osa-085554	Oryza sativa	37.43	7.00e-77	279.00
IUUC-Ola-086998	Oryzias latipes	38.79	8.00e-68	249.00
IUUC-Olu-087818	Ostreococcus lucimarinus	32.05	2.00e-58	218.00
IUUC-Oga-088571	Otolemur garnettii	38.30	5.00e-67	246.00
IUUC-Oar-089526	Ovis aries	34.62	1.00e-74	272.00
IUUC-Ptr-091433	Pan troglodytes	37.03	1.00e-65	242.00
IUUC-Pan-091966	Papio anubis	37.03	2.00e-65	241.00
IUUC-Psi-093458	Pelodiscus sinensis	35.09	2.00e-73	267.00
IUUC-Pma-094343	Petromyzon marinus	37.06	1.00e-42	164.00
IUUC-Pno-095109	Phaeosphaeria nodorum	64.03	0.00e+00	677.00
IUUC-Ppa-095756	Physcomitrella patens	38.62	8.00e-94	335.00
IUUC-Pfo-096514	Poecilia formosa	39.29	1.00e-68	252.00
IUUC-Pab-098477	Pongo abelii	33.50	3.00e-53	200.00
IUUC-Pop-099221	Populus trichocarpa	36.46	7.00e-82	296.00
IUUC-Pca-100791	Procavia capensis	33.18	1.00e-26	112.00
IUUC-Ppe-101812	Prunus persica	35.10	1.00e-81	295.00
IUUC-Pva-102462	Pteropus vampyrus	35.11	1.00e-50	192.00
IUUC-Pgr-103623	Puccinia graminis	43.56	3.00e-75	274.00
IUUC-Ptt-103767	Puccinia triticina	34.90	5.00e-82	296.00
IUUC-Pte-104109	Pyrenophora teres	66.78	0.00e+00	697.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	66.61	0.00e+00	709.00
IUUC-Rno-105351	Rattus norvegicus	37.90	4.00e-65	240.00
IUUC-Sce-106168	Saccharomyces cerevisiae	33.10	1.00e-76	278.00
IUUC-Sha-107491	Sarcophilus harrisii	38.83	2.00e-67	248.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	39.40	2.00e-93	334.00
IUUC-Spo-108174	Schizosaccharomyces pombe	43.01	1.00e-112	398.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	65.29	0.00e+00	674.00
IUUC-Smo-108805	Selaginella moellendorffii	41.52	2.00e-77	281.00
IUUC-Sit-110361	Setaria italica	36.40	4.00e-78	283.00
IUUC-Sly-110965	Solanum lycopersicum	36.09	9.00e-76	275.00
IUUC-Sar-113355	Sorex araneus	37.17	7.00e-53	199.00
IUUC-Sbi-114778	Sorghum bicolor	44.01	3.00e-75	273.00
IUUC-Sre-115011	Sporisorium reilianum	45.95	3.00e-83	300.00
IUUC-Ssc-116273	Sus scrofa	38.19	4.00e-66	243.00
IUUC-Tgu-117063	Taeniopygia guttata	34.84	5.00e-76	276.00
IUUC-Tru-118381	Takifugu rubripes	34.89	7.00e-77	279.00
IUUC-Tsy-119076	Tarsius syrichta	28.36	1.00e-25	108.00
IUUC-Tni-119941	Tetraodon nigroviridis	40.05	3.00e-71	260.00
IUUC-Tca-121246	Theobroma cacao	36.99	1.00e-83	301.00
IUUC-Tre-121969	Trichoderma reesei	58.47	6.00e-170	588.00
IUUC-Tvi-122543	Trichoderma virens	58.82	0.00e+00	625.00
IUUC-Tae-125484	Triticum aestivum	44.27	8.00e-75	272.00
IUUC-Tur-126128	Triticum urartu	37.27	5.00e-21	94.00
IUUC-Tbe-128030	Tupaia belangeri	33.17	2.00e-53	201.00
IUUC-Ttr-128701	Tursiops truncatus	37.39	1.00e-51	194.00
IUUC-Uma-129657	Ustilago maydis	39.27	2.00e-100	357.00
IUUC-Vda-129723	Verticillium dahliae	57.51	0.00e+00	642.00
IUUC-Vpa-130284	Vicugna pacos	32.85	9.00e-27	112.00
IUUC-Vvi-131037	Vitis vinifera	37.88	4.00e-85	306.00
IUUC-Xtr-132235	Xenopus tropicalis	39.30	4.00e-72	263.00
IUUC-Xma-133840	Xiphophorus maculatus	39.29	1.00e-68	251.00
IUUC-Yli-134453	Yarrowia lipolytica	45.66	9.00e-119	418.00
IUUC-Zma-135791	Zea mays	36.55	5.00e-80	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence