iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022000

Ensembl Protein ID

ENSCPOP00000001232.2

UniProt Accession

H0UW14; H0UW14_CAVPO

Genbank Protein ID

ENSCPOP00000001232

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02031333

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000001359.3	ENSCPOT00000001378.2	ENSCPOP00000001232.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.00e-16	59.6	429	485

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ i ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 429  RVRALYDYEGQEHDELSFKAGDELTKI-EDEDEQGWCKG-RLDSGQVGLYPANYVEAIQ 485
           689************************.9**********.59*************9885 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MSVTYDDSTG VEVCSDSFWE VGNYKRTVKR IDDGHRLCSD LMNCLHERAR IEKSYALQLT 60
EWARRWRQLV EKGPQYGTVE KAWVSFMSEA EGVSELHLDV KALLMNEDFE KIKNWQKEAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGTCA CTTACGACGA TTCCACTGGA GTAGAAGTGT GCAGCGACAG CTTCTGGGAG 60
GTAATGCTCT TCTCTTCTGG AGAGCGCAGA GTCCAGGCCG AGGACGCCCG ACAGGCTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	89.71	0.00e+00	836.00
IUUC-Apl-003574	Anas platyrhynchos	83.16	0.00e+00	759.00
IUUC-Aca-004251	Anolis carolinensis	78.97	0.00e+00	729.00
IUUC-Ame-011756	Astyanax mexicanus	64.90	0.00e+00	668.00
IUUC-Bta-013193	Bos taurus	88.48	0.00e+00	798.00
IUUC-Cel-018168	Caenorhabditis elegans	31.36	4.00e-61	228.00
IUUC-Cja-018756	Callithrix jacchus	89.30	0.00e+00	799.00
IUUC-Cfa-020545	Canis familiaris	89.92	0.00e+00	863.00
IUUC-Csa-024030	Chlorocebus sabaeus	88.54	0.00e+00	717.00
IUUC-Cin-025707	Ciona intestinalis	42.30	5.00e-107	381.00
IUUC-Dre-028104	Danio rerio	61.65	4.00e-164	570.00
IUUC-Dno-029429	Dasypus novemcinctus	89.21	0.00e+00	766.00
IUUC-Dor-030122	Dipodomys ordii	83.74	0.00e+00	756.00
IUUC-Dme-032120	Drosophila melanogaster	42.39	3.00e-103	369.00
IUUC-Eca-033367	Equus caballus	87.24	0.00e+00	810.00
IUUC-Eeu-034821	Erinaceus europaeus	72.43	0.00e+00	649.00
IUUC-Fca-036079	Felis catus	89.32	0.00e+00	826.00
IUUC-Fal-036682	Ficedula albicollis	83.40	0.00e+00	752.00
IUUC-Gmo-039681	Gadus morhua	62.78	3.00e-152	531.00
IUUC-Gga-040717	Gallus gallus	83.19	0.00e+00	754.00
IUUC-Gac-042262	Gasterosteus aculeatus	63.66	2.00e-173	601.00
IUUC-Ggo-044841	Gorilla gorilla	89.09	0.00e+00	773.00
IUUC-Hsa-046411	Homo sapiens	89.30	0.00e+00	775.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	89.51	0.00e+00	795.00
IUUC-Loc-051975	Lepisosteus oculatus	68.55	0.00e+00	672.00
IUUC-Laf-053839	Loxodonta africana	85.39	0.00e+00	793.00
IUUC-Mcc-055783	Macaca mulatta	89.51	0.00e+00	778.00
IUUC-Mga-060087	Meleagris gallopavo	77.66	0.00e+00	684.00
IUUC-Mvi-060548	Microbotryum violaceum	40.74	4.00e-07	50.80
IUUC-Mmr-060827	Microcebus murinus	90.95	0.00e+00	846.00
IUUC-Mmu-064109	Mus musculus	90.12	0.00e+00	835.00
IUUC-Mpu-066591	Mustela putorius furo	89.92	0.00e+00	840.00
IUUC-Mlu-067826	Myotis lucifugus	89.51	0.00e+00	836.00
IUUC-Nle-069797	Nomascus leucogenys	89.51	0.00e+00	777.00
IUUC-Oan-073076	Ornithorhynchus anatinus	82.32	2.00e-155	541.00
IUUC-Ocu-074425	Oryctolagus cuniculus	90.12	0.00e+00	811.00
IUUC-Oba-075752	Oryza barthii	39.44	1.60e-02	36.60
IUUC-Ola-087556	Oryzias latipes	64.38	2.00e-163	568.00
IUUC-Oga-089009	Otolemur garnettii	83.91	0.00e+00	769.00
IUUC-Oar-089806	Ovis aries	88.48	0.00e+00	798.00
IUUC-Ptr-091111	Pan troglodytes	88.89	0.00e+00	770.00
IUUC-Pan-091749	Papio anubis	89.27	0.00e+00	761.00
IUUC-Psi-093704	Pelodiscus sinensis	84.47	0.00e+00	778.00
IUUC-Pfo-096680	Poecilia formosa	62.50	6.00e-170	590.00
IUUC-Pab-098584	Pongo abelii	88.33	1.00e-149	522.00
IUUC-Pva-102649	Pteropus vampyrus	87.86	0.00e+00	795.00
IUUC-Rno-105431	Rattus norvegicus	89.75	0.00e+00	858.00
IUUC-Sha-106641	Sarcophilus harrisii	87.12	0.00e+00	798.00
IUUC-Sar-113461	Sorex araneus	78.60	0.00e+00	711.00
IUUC-Ssc-115349	Sus scrofa	89.48	0.00e+00	806.00
IUUC-Tgu-116876	Taeniopygia guttata	83.19	0.00e+00	753.00
IUUC-Tru-118306	Takifugu rubripes	64.57	3.00e-174	604.00
IUUC-Tsy-118901	Tarsius syrichta	80.00	8.00e-148	516.00
IUUC-Tni-120120	Tetraodon nigroviridis	66.73	3.00e-176	611.00
IUUC-Xtr-132925	Xenopus tropicalis	78.85	0.00e+00	738.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence