iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090178

Ensembl Protein ID

ENSOARP00000018044.1

UniProt Accession

W5Q5Q4; W5Q5Q4_SHEEP

Genbank Protein ID

ENSOARP00000018044

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01063673

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000016804.1	ENSOART00000018296.1	ENSOARP00000018044.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	7.70e-06	26.2	21	90
E3 adaptor/Cullin RING/DCX/DWD	3.20e-17	62.1	221	254

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 71   kpkaglrseaaaapapapaptptpeegpdaglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
            p +g   + aa p+  p  +  p  gp    l  lpee+l+ i+++ld + l+r+a+vcr +++++s + lw+++
   Q: 21   GPASGA-GNVAAGPSGEP--ACRPAAGP---ALLCLPEELLLLIFSYLDMQALGRLAQVCRWLRRFTSCDLLWRRI 90
           333332.22333333333..33344454...5789********************************999**9986 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H  +v+c++  ++++vsGs+D t kvW l +g+l
   Q: 221  HVQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRL 254
           9999*****9449***************999875 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

GRPRGRSWVA RAAWGPPGTV GPASGAGNVA AGPSGEPACR PAAGPALLCL PEELLLLIFS 60
YLDMQALGRL AQVCRWLRRF TSCDLLWRRI ARASPPPPRP RAGPRPGMAS VPVKERVKVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCGGCCCC GCGGCCGCTC ATGGGTAGCC AGGGCGGCGT GGGGGCCCCC GGGAACGGTG 60
GGCCCGGCGA GGGNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	94.67	0.00e+00	717.00
IUUC-Apl-003837	Anas platyrhynchos	71.60	8.00e-142	496.00
IUUC-Aca-004776	Anolis carolinensis	65.86	3.00e-131	461.00
IUUC-Ame-010651	Astyanax mexicanus	61.49	1.00e-112	399.00
IUUC-Bta-013495	Bos taurus	96.80	0.00e+00	701.00
IUUC-Cja-018901	Callithrix jacchus	94.32	0.00e+00	673.00
IUUC-Cfa-021251	Canis familiaris	93.60	0.00e+00	709.00
IUUC-Cpo-021750	Cavia porcellus	93.54	0.00e+00	641.00
IUUC-Csa-024026	Chlorocebus sabaeus	93.51	0.00e+00	703.00
IUUC-Cho-024496	Choloepus hoffmanni	72.43	4.00e-146	510.00
IUUC-Cin-025142	Ciona intestinalis	28.98	6.00e-20	90.90
IUUC-Csv-025883	Ciona savignyi	37.80	1.00e-60	226.00
IUUC-Dre-027447	Danio rerio	58.02	5.00e-121	427.00
IUUC-Dno-029572	Dasypus novemcinctus	79.68	2.00e-167	582.00
IUUC-Dor-030982	Dipodomys ordii	85.41	2.00e-180	624.00
IUUC-Dme-031804	Drosophila melanogaster	23.01	2.00e-12	66.60
IUUC-Ete-032917	Echinops telfairi	94.77	0.00e+00	649.00
IUUC-Eca-033969	Equus caballus	94.15	0.00e+00	683.00
IUUC-Eeu-034850	Erinaceus europaeus	83.24	4.00e-176	610.00
IUUC-Fca-036182	Felis catus	90.93	0.00e+00	673.00
IUUC-Fal-037391	Ficedula albicollis	66.40	2.00e-143	502.00
IUUC-Gmo-038632	Gadus morhua	55.61	1.00e-117	416.00
IUUC-Gga-040783	Gallus gallus	69.89	3.00e-148	518.00
IUUC-Gac-042314	Gasterosteus aculeatus	54.91	3.00e-101	362.00
IUUC-Ggo-044739	Gorilla gorilla	93.51	0.00e+00	701.00
IUUC-Hsa-046705	Homo sapiens	94.05	0.00e+00	672.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	97.23	4.00e-169	587.00
IUUC-Loc-052397	Lepisosteus oculatus	65.37	2.00e-131	462.00
IUUC-Laf-054544	Loxodonta africana	96.33	0.00e+00	654.00
IUUC-Meu-056363	Macropus eugenii	58.46	5.00e-101	360.00
IUUC-Mga-059275	Meleagris gallopavo	73.04	4.00e-143	500.00
IUUC-Mmr-060906	Microcebus murinus	93.51	0.00e+00	700.00
IUUC-Mdo-062400	Monodelphis domestica	74.67	3.00e-163	567.00
IUUC-Mmu-063556	Mus musculus	89.72	0.00e+00	675.00
IUUC-Mpu-066500	Mustela putorius furo	94.40	0.00e+00	715.00
IUUC-Mlu-068074	Myotis lucifugus	97.23	0.00e+00	659.00
IUUC-Nle-069601	Nomascus leucogenys	93.78	0.00e+00	702.00
IUUC-Opr-070904	Ochotona princeps	84.81	4.00e-135	474.00
IUUC-Ont-072679	Oreochromis niloticus	54.44	3.00e-111	394.00
IUUC-Oan-073434	Ornithorhynchus anatinus	69.30	7.00e-75	273.00
IUUC-Ocu-074649	Oryctolagus cuniculus	92.70	0.00e+00	693.00
IUUC-Ola-087336	Oryzias latipes	48.13	2.00e-93	335.00
IUUC-Oga-088590	Otolemur garnettii	90.75	0.00e+00	655.00
IUUC-Pan-092881	Papio anubis	93.78	0.00e+00	702.00
IUUC-Pfo-096176	Poecilia formosa	54.55	6.00e-103	367.00
IUUC-Pab-098285	Pongo abelii	93.78	0.00e+00	703.00
IUUC-Pca-100888	Procavia capensis	87.47	0.00e+00	645.00
IUUC-Pva-102184	Pteropus vampyrus	80.27	5.00e-166	577.00
IUUC-Rno-105668	Rattus norvegicus	90.23	0.00e+00	679.00
IUUC-Sha-106629	Sarcophilus harrisii	77.33	7.00e-154	536.00
IUUC-Ssc-116183	Sus scrofa	95.20	0.00e+00	720.00
IUUC-Tgu-116630	Taeniopygia guttata	68.82	8.00e-151	526.00
IUUC-Tru-118761	Takifugu rubripes	51.34	2.00e-108	385.00
IUUC-Tni-120651	Tetraodon nigroviridis	52.48	6.00e-60	223.00
IUUC-Ttr-128582	Tursiops truncatus	93.87	0.00e+00	671.00
IUUC-Vpa-130431	Vicugna pacos	75.76	2.00e-96	345.00
IUUC-Xtr-132655	Xenopus tropicalis	65.23	2.00e-140	492.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence