iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091266

Ensembl Protein ID

ENSPTRP00000031388.3

UniProt Accession

H2QTA9; H2QTA9_PANTR

Genbank Protein ID

ENSPTRP00000031388

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03045945

Gene Name

PHIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000018365.6	ENSPTRT00000033966.3	ENSPTRP00000031388.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.20e-33	111.0	138	175
UBD/Beta-Prp	1.50e-64	218.0	139	355

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 138  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWATDDGRLL 175
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h s ++cv+f + ++ ++tgs+d  +k+w +++g ll++l gh ae++++  + +  +++ gs D++i+vw l+t+ ++ +l+gh++s+
   Q: 139  HLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASI 227
           5567889************************************************99******************************** PP
   S: 98   lslsfsp....sgdklvsGshdrtirvwdletgqclee......tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkl..lr 173
           +sl+fsp    s+ +l s+++d ti  w ++ g+   +      t++++ gv ++ ++ + g   l++Gs+D ++r++   +g+   + 
   Q: 228  TSLQFSPlcsgSKRYLSSTGADGTICFWLWDAGTLKINprpakfTERPRPGVQMICSSFSAGgMFLATGSTDHIIRVYFFGSGQPekIS 316
           *********877799************9888888887788************9988877777799*************99666651166 PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtge 213
           +l+  htd+v s++f+ +++++vsgs+dgt  +w++++ e
   Q: 317  ELEF-HTDKVDSIQFSNTSNRFVSGSCDGTAGIWQFKRRE 355
           7788.******************************99765 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

LLPRRTDWTG KEHPRTYQNL VKYYRHLAPD HLLQICHRLG PLLEQEIPQS VPGVQTLLGA 60
GRQSLLRTNK SCKHVVWKGS ALAALHCGRP PESPVNYGSP PSIADTLFSR KLNGKYRLER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGCTGCTG CCCCGGCGCA CCGACTGGAC CGGGAAGGAG CATCCCAGGA CCTACCAGAA 60
TCTGGTGAGA CATTCACGTC GCAGAGCAAA GAAACTTTTC CCTGAGTCGA ATAAAAATTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002299	Ailuropoda melanoleuca	96.34	0.00e+00	3192.00
IUUC-Apl-003700	Anas platyrhynchos	86.49	0.00e+00	2858.00
IUUC-Aca-004474	Anolis carolinensis	82.30	0.00e+00	2759.00
IUUC-Bta-013125	Bos taurus	95.45	0.00e+00	3100.00
IUUC-Cja-018868	Callithrix jacchus	95.84	0.00e+00	3274.00
IUUC-Cfa-021179	Canis familiaris	95.89	0.00e+00	3095.00
IUUC-Cpo-022077	Cavia porcellus	91.21	0.00e+00	3065.00
IUUC-Csa-023618	Chlorocebus sabaeus	98.54	0.00e+00	3316.00
IUUC-Cho-024794	Choloepus hoffmanni	90.54	0.00e+00	873.00
IUUC-Dre-028029	Danio rerio	80.31	0.00e+00	1280.00
IUUC-Dno-030048	Dasypus novemcinctus	96.12	0.00e+00	3173.00
IUUC-Dor-030195	Dipodomys ordii	89.58	0.00e+00	1448.00
IUUC-Ete-032748	Echinops telfairi	83.58	0.00e+00	1158.00
IUUC-Eca-034274	Equus caballus	96.99	0.00e+00	3164.00
IUUC-Eeu-034688	Erinaceus europaeus	84.79	0.00e+00	1409.00
IUUC-Fca-035451	Felis catus	95.62	0.00e+00	3047.00
IUUC-Fal-037465	Ficedula albicollis	85.85	0.00e+00	2858.00
IUUC-Gmo-039451	Gadus morhua	68.38	0.00e+00	721.00
IUUC-Gga-040798	Gallus gallus	86.06	0.00e+00	2895.00
IUUC-Hsa-046757	Homo sapiens	99.55	0.00e+00	3306.00
IUUC-Hvu-047706	Hordeum vulgare	31.56	3.00e-36	145.00
IUUC-Itr-048843	Ictidomys tridecemlineatus	93.89	0.00e+00	1185.00
IUUC-Lch-050646	Latimeria chalumnae	78.27	0.00e+00	2680.00
IUUC-Laf-054140	Loxodonta africana	95.85	0.00e+00	3197.00
IUUC-Mcc-055061	Macaca mulatta	98.71	0.00e+00	3321.00
IUUC-Mmr-060837	Microcebus murinus	96.25	0.00e+00	1632.00
IUUC-Mdo-061903	Monodelphis domestica	95.01	0.00e+00	1635.00
IUUC-Mmu-063772	Mus musculus	94.60	0.00e+00	3179.00
IUUC-Mpu-066359	Mustela putorius furo	96.18	0.00e+00	2941.00
IUUC-Mlu-067928	Myotis lucifugus	94.88	0.00e+00	3200.00
IUUC-Nle-070094	Nomascus leucogenys	99.38	0.00e+00	3306.00
IUUC-Opr-070971	Ochotona princeps	74.22	0.00e+00	947.00
IUUC-Ont-072221	Oreochromis niloticus	76.38	0.00e+00	1263.00
IUUC-Oan-073185	Ornithorhynchus anatinus	87.35	0.00e+00	2882.00
IUUC-Ocu-074033	Oryctolagus cuniculus	94.88	0.00e+00	2862.00
IUUC-Oin-079669	Oryza indica	30.82	6.00e-51	195.00
IUUC-Olo-080755	Oryza longistaminata	31.12	4.00e-53	204.00
IUUC-Oni-082991	Oryza nivara	27.34	2.00e-38	155.00
IUUC-Oga-088578	Otolemur garnettii	96.42	0.00e+00	3152.00
IUUC-Oar-090247	Ovis aries	95.85	0.00e+00	3107.00
IUUC-Pan-092734	Papio anubis	98.65	0.00e+00	3319.00
IUUC-Pfo-096191	Poecilia formosa	72.56	0.00e+00	1993.00
IUUC-Pab-098402	Pongo abelii	99.33	0.00e+00	3304.00
IUUC-Pca-101128	Procavia capensis	86.35	0.00e+00	2850.00
IUUC-Pva-103058	Pteropus vampyrus	95.23	0.00e+00	1575.00
IUUC-Rno-106013	Rattus norvegicus	93.12	0.00e+00	3117.00
IUUC-Sha-107496	Sarcophilus harrisii	90.92	0.00e+00	3081.00
IUUC-Sit-110017	Setaria italica	30.84	6.00e-54	206.00
IUUC-Sar-113520	Sorex araneus	90.80	0.00e+00	1534.00
IUUC-Ssc-115461	Sus scrofa	92.75	0.00e+00	3065.00
IUUC-Tgu-116821	Taeniopygia guttata	85.63	0.00e+00	2856.00
IUUC-Tsy-119132	Tarsius syrichta	85.10	0.00e+00	2579.00
IUUC-Tbe-127479	Tupaia belangeri	93.19	0.00e+00	1462.00
IUUC-Ttr-128427	Tursiops truncatus	91.96	0.00e+00	3022.00
IUUC-Vpa-130160	Vicugna pacos	93.14	0.00e+00	3036.00
IUUC-Xtr-132717	Xenopus tropicalis	74.30	0.00e+00	2499.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence