iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028634

UUCD1 version

UUC-DaR-01205

Ensembl Protein ID

ENSDARP00000073472.4

UniProt Accession

Q6AXK9; Q6AXK9_DANRE

Genbank Protein ID

AAH79495.1; AAI52623.1

Protein Name

THO complex 3

Genbank Nucleotide ID

BX511257; BC152622

Gene Name

thoc3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000056517.4	ENSDART00000079016.4	ENSDARP00000073472.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.50e-30	103.0	68	106
UBD/Beta-Prp	3.50e-41	142.2	20	145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvll 36
           gH dsv  l++  ++ +l+v++s+D+ti++WD+rt ++ 
   Q: 68   GHGDSVDQLCWhpTNpDLFVTASGDKTIRIWDVRTTKCM 106
           8***********8557*******************9986 PP

UBD/Beta-Prp

   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrt 174
           + + +h+++v s+++s +g++l+sGs d+t+ v+ le++  ++e   +gh ++v  +++hp++ +l+v++s D+t+r+Wd++t k++ t
   Q: 20   REFPAHSAKVHSVAWSCDGKRLASGSFDKTASVFVLEKDRLVKEnNYRGHGDSVDQLCWHPTNpDLFVTASGDKTIRIWDVRTTKCMAT 108
           56779*************************************998899***************************************** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtge 213
            +   ++    + ++++g+ ++ g +d  v++ d +t +
   Q: 109  VST--KGENINICWSPDGQTIAVGNKDDVVTFIDAKTHR 145
           *86..55555677*********************99765 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MASSYYQEMQ EVFRNNNKSR EFPAHSAKVH SVAWSCDGKR LASGSFDKTA SVFVLEKDRL 60
VKENNYRGHG DSVDQLCWHP TNPDLFVTAS GDKTIRIWDV RTTKCMATVS TKGENINICW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAAGCAGAA CTTCAAGCAT GGCGTCCTCG TACTATCAGG AGATGCAGGA GGTGTTCAGG 60
AATAACAATA AAAGCAGAGA GTTCCCGGCT CACAGTGCTA AAGTGCACTC GGTGGCCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR013979--TIF_beta_prop-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF08662--eIF2A
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000445--C:THO complex part of transcription export complex
GO:0006406--P:mRNA export from nucleus

KEGG

dre:445302

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000099	Aegilops tauschii	48.20	5.00e-87	314.00
IUUC-Aml-001264	Ailuropoda melanoleuca	91.25	1.00e-179	622.00
IUUC-Atr-003050	Amborella trichopoda	51.27	3.00e-95	341.00
IUUC-Apl-003426	Anas platyrhynchos	81.20	7.00e-125	439.00
IUUC-Aca-004931	Anolis carolinensis	90.99	3.00e-121	427.00
IUUC-Aly-006237	Arabidopsis lyrata	50.33	8.00e-92	330.00
IUUC-Ath-007581	Arabidopsis thaliana	50.66	3.00e-92	331.00
IUUC-Acl-008253	Aspergillus clavatus	27.70	8.00e-39	154.00
IUUC-Afl-008519	Aspergillus flavus	31.71	3.00e-41	162.00
IUUC-Afu-008886	Aspergillus fumigatus	26.50	4.00e-36	145.00
IUUC-Ani-009275	Aspergillus nidulans	30.00	4.00e-40	159.00
IUUC-Ang-009862	Aspergillus niger	29.93	2.00e-39	156.00
IUUC-Ate-010247	Aspergillus terreus	28.48	2.00e-38	153.00
IUUC-Ame-010828	Astyanax mexicanus	97.83	0.00e+00	663.00
IUUC-Bgr-012163	Blumeria graminis	28.74	1.00e-32	133.00
IUUC-Bta-013514	Bos taurus	78.75	4.00e-154	537.00
IUUC-Bci-013639	Botrytis cinerea	30.16	4.00e-46	178.00
IUUC-Bdi-015049	Brachypodium distachyon	48.72	2.00e-86	312.00
IUUC-Bol-015401	Brassica oleracea	50.32	1.00e-89	323.00
IUUC-Bra-017867	Brassica rapa	50.00	3.00e-89	321.00
IUUC-Cel-018699	Caenorhabditis elegans	33.75	4.00e-46	178.00
IUUC-Cja-019591	Callithrix jacchus	90.94	9.00e-179	619.00
IUUC-Cfa-020692	Canis familiaris	91.25	5.00e-180	623.00
IUUC-Cpo-022135	Cavia porcellus	77.88	3.00e-149	521.00
IUUC-Cre-022572	Chlamydomonas reinhardtii	34.39	3.00e-43	169.00
IUUC-Csa-023408	Chlorocebus sabaeus	91.25	5.00e-179	620.00
IUUC-Cho-024340	Choloepus hoffmanni	82.93	2.00e-95	341.00
IUUC-Cin-025418	Ciona intestinalis	73.19	2.00e-56	211.00
IUUC-Csv-026130	Ciona savignyi	66.67	2.00e-130	458.00
IUUC-Cgl-026744	Colletotrichum gloeosporioides	31.14	4.00e-44	171.00
IUUC-Dno-029449	Dasypus novemcinctus	91.56	2.00e-180	624.00
IUUC-Dor-030301	Dipodomys ordii	72.56	7.00e-109	386.00
IUUC-Dse-031341	Dothistroma septosporum	28.42	5.00e-33	135.00
IUUC-Dme-031674	Drosophila melanogaster	63.46	4.00e-122	431.00
IUUC-Ete-033136	Echinops telfairi	90.62	9.00e-179	619.00
IUUC-Eca-034432	Equus caballus	83.44	3.00e-163	568.00
IUUC-Fca-035694	Felis catus	91.25	5.00e-180	623.00
IUUC-Fal-037328	Ficedula albicollis	92.19	1.00e-180	625.00
IUUC-Fox-037894	Fusarium oxysporum	32.25	4.00e-47	181.00
IUUC-Fso-038266	Fusarium solani	30.35	7.00e-44	171.00
IUUC-Gmo-039617	Gadus morhua	95.34	0.00e+00	650.00
IUUC-Ggr-039819	Gaeumannomyces graminis	29.05	4.00e-40	158.00
IUUC-Gga-041164	Gallus gallus	91.48	9.00e-178	616.00
IUUC-Gac-042407	Gasterosteus aculeatus	95.65	0.00e+00	651.00
IUUC-Gma-043663	Glycine max	50.00	2.00e-92	332.00
IUUC-Ggo-044989	Gorilla gorilla	91.25	6.00e-179	619.00
IUUC-Hsa-046784	Homo sapiens	91.25	4.00e-179	620.00
IUUC-Hvu-047633	Hordeum vulgare	48.37	1.00e-60	225.00
IUUC-Itr-048184	Ictidomys tridecemlineatus	69.88	1.00e-125	442.00
IUUC-Kpa-049182	Komagataella pastoris	25.70	6.00e-19	88.60
IUUC-Lch-049894	Latimeria chalumnae	92.86	0.00e+00	635.00
IUUC-Lpe-051061	Leersia perrieri	41.83	5.00e-64	237.00
IUUC-Loc-052424	Lepisosteus oculatus	96.58	0.00e+00	655.00
IUUC-Lma-053127	Leptosphaeria maculans	31.33	1.00e-47	184.00
IUUC-Laf-053396	Loxodonta africana	91.25	1.00e-179	622.00
IUUC-Mcc-055517	Macaca mulatta	91.25	4.00e-179	620.00
IUUC-Meu-056034	Macropus eugenii	91.88	0.00e+00	626.00
IUUC-Mor-057011	Magnaporthe oryzae	26.50	9.00e-27	114.00
IUUC-Mpo-057490	Magnaporthe poae	29.05	2.00e-40	159.00
IUUC-Mtr-057927	Medicago truncatula	50.79	4.00e-94	337.00
IUUC-Mla-058945	Melampsora laricipopulina	35.25	1.00e-47	183.00
IUUC-Mga-060155	Meleagris gallopavo	90.44	1.00e-135	475.00
IUUC-Mvi-060344	Microbotryum violaceum	37.95	4.00e-53	201.00
IUUC-Mmr-060834	Microcebus murinus	91.56	2.00e-180	625.00
IUUC-Mdo-062587	Monodelphis domestica	91.82	3.00e-180	624.00
IUUC-Mmu-063395	Mus musculus	91.56	3.00e-180	624.00
IUUC-Mac-064579	Musa acuminata	50.66	3.00e-93	335.00
IUUC-Mpu-066688	Mustela putorius furo	90.44	3.00e-149	521.00
IUUC-Mlu-067299	Myotis lucifugus	91.56	2.00e-180	625.00
IUUC-Nfi-068562	Neosartorya fischeri	29.15	4.00e-38	152.00
IUUC-Ncr-068654	Neurospora crassa	29.51	5.00e-35	141.00
IUUC-Nle-069736	Nomascus leucogenys	90.31	5.00e-177	613.00
IUUC-Ont-071763	Oreochromis niloticus	94.72	0.00e+00	646.00
IUUC-Ocu-074909	Oryctolagus cuniculus	91.56	4.00e-180	623.00
IUUC-Oba-075902	Oryza barthii	42.16	1.00e-64	239.00
IUUC-Obr-076613	Oryza brachyantha	49.35	6.00e-84	303.00
IUUC-Ogl-077009	Oryza glaberrima	47.90	3.00e-82	298.00
IUUC-Ogu-078344	Oryza glumaepatula	42.16	1.00e-64	239.00
IUUC-Oin-079773	Oryza indica	47.90	3.00e-82	298.00
IUUC-Olo-080474	Oryza longistaminata	45.08	5.00e-46	177.00
IUUC-Ome-081837	Oryza meridionalis	44.72	1.00e-32	132.00
IUUC-Oni-082263	Oryza nivara	42.16	1.00e-64	239.00
IUUC-Opu-083813	Oryza punctata	47.90	4.00e-82	298.00
IUUC-Oru-084610	Oryza rufipogon	42.16	1.00e-64	239.00
IUUC-Osa-085415	Oryza sativa	47.90	3.00e-82	298.00
IUUC-Ola-086659	Oryzias latipes	95.65	0.00e+00	650.00
IUUC-Olu-087649	Ostreococcus lucimarinus	38.01	4.00e-55	208.00
IUUC-Oga-087923	Otolemur garnettii	91.25	8.00e-180	622.00
IUUC-Oar-089688	Ovis aries	88.12	3.00e-174	603.00
IUUC-Ptr-091628	Pan troglodytes	91.25	4.00e-179	620.00
IUUC-Pan-092586	Papio anubis	90.40	1.00e-177	615.00
IUUC-Psi-093701	Pelodiscus sinensis	90.20	1.00e-110	391.00
IUUC-Pma-094465	Petromyzon marinus	84.71	4.00e-166	577.00
IUUC-Pno-094767	Phaeosphaeria nodorum	33.33	3.00e-46	180.00
IUUC-Ppa-095195	Physcomitrella patens	52.94	2.00e-96	345.00
IUUC-Pfo-097383	Poecilia formosa	95.03	0.00e+00	649.00
IUUC-Pab-098669	Pongo abelii	91.25	3.00e-179	620.00
IUUC-Pop-099409	Populus trichocarpa	51.15	6.00e-93	333.00
IUUC-Pca-100769	Procavia capensis	79.69	7.00e-150	523.00
IUUC-Ppe-101321	Prunus persica	50.47	4.00e-93	334.00
IUUC-Pva-102759	Pteropus vampyrus	90.94	3.00e-179	621.00
IUUC-Pgr-103535	Puccinia graminis	35.62	1.00e-53	203.00
IUUC-Ptt-103820	Puccinia triticina	35.95	3.00e-54	205.00
IUUC-Pte-104271	Pyrenophora teres	32.12	2.00e-43	169.00
IUUC-Pyt-104500	Pyrenophora triticirepentis	30.89	4.00e-37	149.00
IUUC-Rno-106126	Rattus norvegicus	91.56	3.00e-180	624.00
IUUC-Sha-107146	Sarcophilus harrisii	91.72	4.00e-176	610.00
IUUC-Sja-107865	Schizosaccharomyces japonicus	36.92	2.00e-54	206.00
IUUC-Spo-108324	Schizosaccharomyces pombe	41.54	1.00e-60	226.00
IUUC-Smo-108990	Selaginella moellendorffii	52.10	9.00e-95	340.00
IUUC-Sit-110773	Setaria italica	49.67	1.00e-83	303.00
IUUC-Sly-111619	Solanum lycopersicum	51.48	5.00e-95	340.00
IUUC-Stu-112241	Solanum tuberosum	51.80	2.00e-95	342.00
IUUC-Sbi-114842	Sorghum bicolor	50.33	1.00e-84	306.00
IUUC-Sre-115070	Sporisorium reilianum	33.03	2.00e-49	189.00
IUUC-Ssc-115581	Sus scrofa	91.25	5.00e-180	623.00
IUUC-Tgu-117354	Taeniopygia guttata	90.73	9.00e-173	598.00
IUUC-Tru-117745	Takifugu rubripes	94.10	0.00e+00	644.00
IUUC-Tni-120050	Tetraodon nigroviridis	93.17	0.00e+00	637.00
IUUC-Tca-121279	Theobroma cacao	51.80	3.00e-93	334.00
IUUC-Tre-121952	Trichoderma reesei	30.82	1.00e-46	180.00
IUUC-Tvi-122581	Trichoderma virens	30.72	1.00e-46	180.00
IUUC-Tae-123910	Triticum aestivum	50.34	3.00e-87	315.00
IUUC-Tur-126279	Triticum urartu	48.36	5.00e-86	311.00
IUUC-Tme-127000	Tuber melanosporum	30.08	3.00e-38	152.00
IUUC-Ttr-128405	Tursiops truncatus	93.89	1.00e-150	525.00
IUUC-Uma-129547	Ustilago maydis	36.06	2.00e-49	189.00
IUUC-Vda-129689	Verticillium dahliae	28.89	4.00e-36	145.00
IUUC-Vvi-131345	Vitis vinifera	51.48	2.00e-94	338.00
IUUC-Xtr-132136	Xenopus tropicalis	86.65	5.00e-170	590.00
IUUC-Xma-133767	Xiphophorus maculatus	95.03	0.00e+00	648.00
IUUC-Yli-134522	Yarrowia lipolytica	27.14	2.00e-27	116.00
IUUC-Zma-135816	Zea mays	50.00	7.00e-84	303.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence