iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003434

Ensembl Protein ID

ENSAPLP00000003852.1

UniProt Accession

U3I9D1; U3I9D1_ANAPL

Genbank Protein ID

ENSAPLP00000003852

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01094419

Gene Name

TLE4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000004314.1	ENSAPLT00000004459.1	ENSAPLP00000003852.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.00e-20	70.8	588	626

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 588  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 626
           8***********999*********************998 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

NSLKLECEKL ASEKTEMQRH YVMYYEMSYG LNIEMHKQAE IVKRLNAICA QVIPFLSQET 60
SNXXXXXXXX XAKQVTMAEL NAIIGFTNSI SVFHFSQQQQ LQAQHLSHGH GLPVPLTPHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACAGTTTGA AGCTAGAATG TGAAAAACTG GCCAGTGAGA AGACAGAGAT GCAGCGACAT 60
TATGTCATGG TAAGCAAGCT GCATAACAAA TTCAAAATGT CTATTAGCTT GGTGTGCTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0003705--F:transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012646	Bos taurus	87.79	0.00e+00	1127.00
IUUC-Cja-019079	Callithrix jacchus	88.05	0.00e+00	1153.00
IUUC-Cfa-020987	Canis familiaris	87.79	0.00e+00	1150.00
IUUC-Csa-023445	Chlorocebus sabaeus	88.19	0.00e+00	1125.00
IUUC-Cho-024590	Choloepus hoffmanni	79.07	0.00e+00	1046.00
IUUC-Dno-028979	Dasypus novemcinctus	87.48	0.00e+00	1086.00
IUUC-Ete-032887	Echinops telfairi	77.94	0.00e+00	1004.00
IUUC-Eca-034397	Equus caballus	87.63	0.00e+00	1122.00
IUUC-Fca-036030	Felis catus	87.92	0.00e+00	1149.00
IUUC-Fal-037460	Ficedula albicollis	88.46	0.00e+00	1135.00
IUUC-Gga-040416	Gallus gallus	88.59	0.00e+00	1132.00
IUUC-Ggo-045633	Gorilla gorilla	84.56	0.00e+00	1126.00
IUUC-Hsa-046461	Homo sapiens	84.43	0.00e+00	1123.00
IUUC-Laf-053425	Loxodonta africana	88.05	0.00e+00	1152.00
IUUC-Mcc-055766	Macaca mulatta	84.56	0.00e+00	1125.00
IUUC-Mmu-063576	Mus musculus	87.92	0.00e+00	1119.00
IUUC-Mpu-066410	Mustela putorius furo	87.79	0.00e+00	1120.00
IUUC-Mlu-067456	Myotis lucifugus	88.05	0.00e+00	1108.00
IUUC-Nle-069495	Nomascus leucogenys	88.19	0.00e+00	1125.00
IUUC-Ocu-074453	Oryctolagus cuniculus	88.05	0.00e+00	1123.00
IUUC-Oga-087939	Otolemur garnettii	88.32	0.00e+00	1125.00
IUUC-Oar-090347	Ovis aries	87.52	0.00e+00	1103.00
IUUC-Ptr-091048	Pan troglodytes	88.19	0.00e+00	1125.00
IUUC-Pab-097539	Pongo abelii	84.36	0.00e+00	1096.00
IUUC-Rno-105314	Rattus norvegicus	87.61	0.00e+00	1059.00
IUUC-Ssc-116408	Sus scrofa	87.94	0.00e+00	1149.00
IUUC-Tgu-117068	Taeniopygia guttata	87.92	0.00e+00	1158.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence