iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	miRNAMap	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-06	28.3	409	470

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf.................kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC+e +                 +   +++ C H+fh+ Cl ++ + + ++ ++ +CP C+
   Q: 409  CIICMEKLsvasgysdvtdskalgpMVVGRLTKCSHAFHLLCLLAM-YCNGNKDGSLQCPSCK 470
           ******998887776665443222211133577**********888.89999**********6 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAMAPSSSLP QVYPSHVVVA VWEWQDGLGI WHPYSATVCS FIEQQFIRQR GQHFGLGSLA 60
HSIPLGQADP SLAPYIIDLP SWTQFRQDTG TMRSVRRHLF SQNSAPGQGI VWEWLGDDGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGACGCCGA GTTTCACTCC GGCTGCCTCC TGCTCGGAGT CGGAGATATA CTCGGGGGTT 60
CTTCCCAGGC CGAGCCGGAG CTGAGCCCGG AGGTCGGCGC TCCTCTCAAC CTGTTCCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50918--WWE
PS50089--ZF_RING_2

Pfam

PF02825--WWE
PF00097--zf-C3HC4

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0007219--P:Notch signaling pathway

KEGG

rno:304591

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001936	Ailuropoda melanoleuca	82.74	0.00e+00	998.00
IUUC-Apl-003758	Anas platyrhynchos	56.28	3.00e-178	618.00
IUUC-Aca-004841	Anolis carolinensis	65.67	9.00e-98	350.00
IUUC-Aly-006395	Arabidopsis lyrata	28.17	1.00e-04	39.70
IUUC-Ame-011200	Astyanax mexicanus	65.45	2.00e-110	393.00
IUUC-Cja-018934	Callithrix jacchus	84.57	0.00e+00	986.00
IUUC-Cfa-020925	Canis familiaris	81.61	0.00e+00	981.00
IUUC-Cpo-021609	Cavia porcellus	84.52	0.00e+00	1013.00
IUUC-Csa-023891	Chlorocebus sabaeus	84.75	0.00e+00	1017.00
IUUC-Dno-029480	Dasypus novemcinctus	82.58	0.00e+00	974.00
IUUC-Dor-031138	Dipodomys ordii	82.42	0.00e+00	977.00
IUUC-Ete-032479	Echinops telfairi	80.08	6.00e-121	427.00
IUUC-Eca-034342	Equus caballus	82.93	0.00e+00	996.00
IUUC-Eeu-034455	Erinaceus europaeus	69.47	1.00e-98	353.00
IUUC-Fca-036373	Felis catus	83.23	0.00e+00	995.00
IUUC-Fal-037532	Ficedula albicollis	67.95	3.00e-118	419.00
IUUC-Ggo-045222	Gorilla gorilla	74.00	0.00e+00	873.00
IUUC-Hsa-045716	Homo sapiens	84.11	0.00e+00	1008.00
IUUC-Itr-048253	Ictidomys tridecemlineatus	85.16	0.00e+00	1011.00
IUUC-Lch-050520	Latimeria chalumnae	50.56	4.00e-157	548.00
IUUC-Lpe-051456	Leersia perrieri	28.89	5.00e-05	42.40
IUUC-Laf-054290	Loxodonta africana	81.94	0.00e+00	974.00
IUUC-Mcc-054636	Macaca mulatta	85.39	0.00e+00	998.00
IUUC-Meu-056652	Macropus eugenii	82.61	2.00e-113	403.00
IUUC-Mga-059841	Meleagris gallopavo	59.02	0.00e+00	651.00
IUUC-Mmr-060582	Microcebus murinus	83.23	0.00e+00	992.00
IUUC-Mdo-062910	Monodelphis domestica	65.53	0.00e+00	761.00
IUUC-Mmu-063723	Mus musculus	97.42	0.00e+00	1159.00
IUUC-Mac-065583	Musa acuminata	25.81	9.00e-05	40.00
IUUC-Mpu-066817	Mustela putorius furo	76.41	0.00e+00	914.00
IUUC-Mlu-067955	Myotis lucifugus	81.77	0.00e+00	986.00
IUUC-Nle-069055	Nomascus leucogenys	80.73	8.00e-164	570.00
IUUC-Opr-070290	Ochotona princeps	87.99	1.00e-149	523.00
IUUC-Oan-073083	Ornithorhynchus anatinus	53.53	3.00e-144	504.00
IUUC-Ocu-074325	Oryctolagus cuniculus	84.38	0.00e+00	1019.00
IUUC-Obr-076780	Oryza brachyantha	31.88	1.00e-04	41.60
IUUC-Ola-087563	Oryzias latipes	64.25	6.00e-76	278.00
IUUC-Oga-088806	Otolemur garnettii	81.64	0.00e+00	998.00
IUUC-Oar-089906	Ovis aries	76.18	0.00e+00	778.00
IUUC-Ptr-090683	Pan troglodytes	85.07	0.00e+00	1018.00
IUUC-Pan-092356	Papio anubis	85.39	0.00e+00	996.00
IUUC-Psi-093479	Pelodiscus sinensis	60.36	0.00e+00	707.00
IUUC-Pab-098412	Pongo abelii	85.07	0.00e+00	1023.00
IUUC-Pca-100995	Procavia capensis	68.64	7.00e-87	314.00
IUUC-Pva-103068	Pteropus vampyrus	72.51	0.00e+00	839.00
IUUC-Sha-107480	Sarcophilus harrisii	82.09	1.00e-142	499.00
IUUC-Sar-113689	Sorex araneus	72.03	0.00e+00	843.00
IUUC-Ssc-115373	Sus scrofa	91.22	3.00e-155	540.00
IUUC-Tgu-117036	Taeniopygia guttata	60.89	0.00e+00	697.00
IUUC-Tru-118461	Takifugu rubripes	63.49	5.00e-100	358.00
IUUC-Tsy-118930	Tarsius syrichta	83.84	2.00e-129	456.00
IUUC-Tca-121016	Theobroma cacao	40.30	1.00e-05	43.10
IUUC-Tae-125082	Triticum aestivum	28.12	4.00e-05	42.70
IUUC-Tur-126364	Triticum urartu	33.33	6.00e-05	42.40
IUUC-Tbe-127561	Tupaia belangeri	82.26	0.00e+00	957.00
IUUC-Ttr-128688	Tursiops truncatus	68.55	2.00e-144	505.00
IUUC-Xtr-132053	Xenopus tropicalis	50.32	3.00e-160	558.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence