iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042261

UUCD1 version

UUC-GaA-01245

Ensembl Protein ID

ENSGACP00000019800.2

UniProt Accession

G3PQB5; G3PQB5_GASAC

Protein Name

Uncharacterized protein

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000015008.2	ENSGACT00000019838.2	ENSGACP00000019800.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-79	268.2	3	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N gN+CY+N+vLQcL ++ +l e ll+++++k        ++ ++++ + +l+ee+w ++ ++ +p e  ++++++ ++f++y+q
   Q: 3    CGLDNSGNSCYLNAVLQCLCSTVPLVEHLLHRDTRKE----LGRSQCQVAQMFVRLLEEMWLGSGTSCAPVEARSVMCSVLPQFDNYSQ 87
           7******************************433332....255789****************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeed..kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           qDaqE++ fll++l++elkk +++++ +++ ++  + + +        +++++++s+lF+gql  ++ c +c++++ ++++f+ lslp+
   Q: 88   QDAQELMLFLLNALNDELKKVRQHETRRASASRwhRVSGPVCVCGAAATESTTMVSRLFEGQLGYTTLCTHCEHQTRSTQSFTVLSLPI 176
           ******************9977766666655541044445558888999999************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           p+++   k s+qdcL+ f+ +  l+ ++++ c+ c  k+e+   ++l+k Pe+L+lhLkRf  s+++ ++ k+ ++v f  +L+lspf+
   Q: 177  PKDTI--KCSIQDCLSLFFGQTVLTAAEQVLCSACGLKRETAVHTSLDKPPEILMLHLKRF--SCKGRNQVKLRTNVFFSSRLNLSPFL 261
           **995..57****************************************************..78889999****************** PP
   S: 266  tspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
           +s+ ++ +++ +Y+L+avv+H+G l+ GHY+a++ n   + W +fdDs V+ev+ + v++    +aYvl+Y r
   Q: 262  SSSVQS-TVYSSYRLYAVVNHTGHLNMGHYTALCHNACTRcWHCFDDSAVREVRDSLVQS---PNAYVLLYSR 330
           *96655.57***************************87778*******************...********98 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

GVCGLDNSGN SCYLNAVLQC LCSTVPLVEH LLHRDTRKEL GRSQCQVAQM FVRLLEEMWL 60
GSGTSCAPVE ARSVMCSVLP QFDNYSQQDA QELMLFLLNA LNDELKKVRQ HETRRASASR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGTGTGCG GTTTGGACAA CTCGGGCAAC TCGTGCTACT TAAACGCCGT GTTACAGTGC 60
TTGTGTTCCA CTGTGCCCCT CGTGGAGCAC CTCCTTCATC GGGACACTCG CAAGGAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	43.32	6.00e-74	271.00
IUUC-Bta-012753	Bos taurus	41.54	3.00e-66	245.00
IUUC-Cfa-020054	Canis familiaris	41.86	1.00e-64	239.00
IUUC-Cpo-021375	Cavia porcellus	41.37	8.00e-73	267.00
IUUC-Cho-024755	Choloepus hoffmanni	38.11	1.00e-50	193.00
IUUC-Ete-032570	Echinops telfairi	41.18	3.00e-34	138.00
IUUC-Eca-034343	Equus caballus	43.92	9.00e-75	273.00
IUUC-Fca-035920	Felis catus	41.25	1.00e-73	269.00
IUUC-Hsa-046665	Homo sapiens	41.61	1.00e-58	220.00
IUUC-Itr-048167	Ictidomys tridecemlineatus	42.90	8.00e-76	277.00
IUUC-Loc-051880	Lepisosteus oculatus	51.04	4.00e-84	306.00
IUUC-Laf-054494	Loxodonta africana	43.32	4.00e-75	274.00
IUUC-Mcc-055507	Macaca mulatta	43.22	3.00e-70	258.00
IUUC-Mmu-063618	Mus musculus	43.03	3.00e-75	275.00
IUUC-Mpu-066699	Mustela putorius furo	42.43	2.00e-72	266.00
IUUC-Mlu-067672	Myotis lucifugus	44.21	2.00e-75	276.00
IUUC-Opr-070949	Ochotona princeps	39.86	2.00e-51	196.00
IUUC-Ont-072200	Oreochromis niloticus	72.02	8.00e-125	440.00
IUUC-Ocu-074021	Oryctolagus cuniculus	42.31	3.00e-73	268.00
IUUC-Ola-086857	Oryzias latipes	59.83	2.00e-115	408.00
IUUC-Oga-088258	Otolemur garnettii	41.86	8.00e-64	236.00
IUUC-Oar-089881	Ovis aries	40.24	1.00e-70	259.00
IUUC-Ptr-090988	Pan troglodytes	41.00	3.00e-55	208.00
IUUC-Pan-091773	Papio anubis	43.49	1.00e-74	273.00
IUUC-Pfo-096718	Poecilia formosa	58.46	2.00e-100	360.00
IUUC-Pab-097713	Pongo abelii	42.37	9.00e-67	247.00
IUUC-Pva-103172	Pteropus vampyrus	42.53	1.00e-64	239.00
IUUC-Rno-105950	Rattus norvegicus	43.92	4.00e-75	275.00
IUUC-Ssc-116383	Sus scrofa	43.32	5.00e-74	271.00
IUUC-Tru-118574	Takifugu rubripes	66.97	3.00e-122	431.00
IUUC-Tni-120385	Tetraodon nigroviridis	66.37	1.00e-113	402.00
IUUC-Vpa-130044	Vicugna pacos	42.86	3.00e-63	235.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence