iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089822

Ensembl Protein ID

ENSOARP00000017477.1

UniProt Accession

W5Q438; W5Q438_SHEEP

Genbank Protein ID

ENSOARP00000017477

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01069440

Gene Name

GNB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000016272.1	ENSOART00000017724.1	ENSOARP00000017477.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.30e-33	111.8	200	238
UBD/Beta-Prp	2.60e-46	158.3	77	286

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+++v +l++ +d +++vsG+ D +ik+WD+r+  + +
   Q: 200  GHSGDVMSLSLaPDgRTFVSGACDASIKLWDVRDSMCRQ 238
           8***********99999****************988866 PP

UBD/Beta-Prp

   S: 85   kcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl....... 166
            + +tl+gh ++++++++  ++  lvs+s+d  + +wd  t  +++     ++++v++ ++ p+gn ++ G+lD+++ +++l       
   Q: 77   RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVH-AIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLktregnv 164
           5678999999999999999999999999999999999999999999.888899999999999999999999999999999999999999 PP
   S: 167  .........................ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrf 230
                                    +tg+    + g h ++v sls+ ++g+ +vsg++d ++klwd++ + c +t++gh++ ++ v+f
   Q: 165  rvsrelpghtafpsfchlssalwdiETGQQTVGFAG-HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAF 252
           9999999999999999999999999*********99.**************************************************** PP
   S: 231  spnderlvsgssDgsiriWdlrsgdllktlqlhn 264
           +pn+  + +gs+D + r++dlr ++ l ++++ n
   Q: 253  FPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 286
           ***************************9999854 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

PLPGRASAPP LPPLPXRGPQ PPPTPPHGPG AMSELEQLRQ EAEQLRNQIR DARKACGDST 60
LTQITAGLDP VGRIQMRTRR TLRGHLAKIY AMHWGTDSRL LVSASQDGKL IIWDSYTTNK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCTTCCGG GCCGCGCTTC GGCCCCGCCT TTACCCCCGC TTCCCCNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0005925--C:focal adhesion
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0048471--C:perinuclear region of cytoplasm
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001395	Ailuropoda melanoleuca	92.57	3.00e-175	607.00
IUUC-Bta-013430	Bos taurus	93.50	3.00e-177	613.00
IUUC-Cja-019794	Callithrix jacchus	93.50	3.00e-177	613.00
IUUC-Cpo-021865	Cavia porcellus	93.84	2.00e-177	614.00
IUUC-Csa-023572	Chlorocebus sabaeus	93.50	3.00e-177	613.00
IUUC-Dno-029001	Dasypus novemcinctus	93.84	5.00e-177	613.00
IUUC-Eca-034149	Equus caballus	93.50	3.00e-177	613.00
IUUC-Fca-036537	Felis catus	93.50	3.00e-177	613.00
IUUC-Ggo-044543	Gorilla gorilla	93.50	3.00e-177	613.00
IUUC-Hsa-046432	Homo sapiens	93.50	3.00e-177	613.00
IUUC-Itr-048049	Ictidomys tridecemlineatus	93.69	0.00e+00	636.00
IUUC-Laf-053865	Loxodonta africana	93.84	2.00e-177	614.00
IUUC-Mmr-061015	Microcebus murinus	93.50	3.00e-177	613.00
IUUC-Mmu-063737	Mus musculus	93.84	4.00e-177	613.00
IUUC-Mlu-067912	Myotis lucifugus	93.19	1.00e-176	612.00
IUUC-Opr-070866	Ochotona princeps	93.50	3.00e-177	613.00
IUUC-Ocu-074344	Oryctolagus cuniculus	93.50	3.00e-177	613.00
IUUC-Oga-089046	Otolemur garnettii	93.50	3.00e-177	613.00
IUUC-Ptr-091444	Pan troglodytes	93.50	3.00e-177	613.00
IUUC-Pan-092045	Papio anubis	93.50	3.00e-177	613.00
IUUC-Pab-097601	Pongo abelii	92.57	1.00e-175	608.00
IUUC-Pca-100940	Procavia capensis	93.50	3.00e-177	613.00
IUUC-Pva-102229	Pteropus vampyrus	93.19	3.00e-175	607.00
IUUC-Rno-106104	Rattus norvegicus	93.50	3.00e-177	613.00
IUUC-Ssc-115595	Sus scrofa	93.50	3.00e-177	613.00
IUUC-Ttr-128403	Tursiops truncatus	93.50	3.00e-177	613.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence